Ecological comparison of the risks of mother-to-child transmission and clinical manifestations of congenital toxoplasmosis according to prenatal treatment protocol

We compared the relative risks of mother-to-child transmission of Toxoplasma gondii and clinical manifestations due to congenital toxoplasmosis associated with intensive prenatal treatment in Lyon and Austria, short term treatment in 51% of Dutch women, and no treatment in Danish women. For each cohort, relative risks were standardized for gestation at seroconversion. In total, 856 mother–child pairs were studied: 549 in Lyon, 133 in Austria, 123 in Denmark and 51 in The Netherlands. The relative risk for mother-to-child transmission compared to Lyon was 1·24 (95% CI: 0·88, 1·59) in Austria; 0·59 (0·41, 0·81) in Denmark; and 0·65 (0·37, 1·01) in The Netherlands. Relative risks for clinical manifestations compared with Lyon (adjusted for follow-up to age 3 years) were: Austria 0·19 (0·04, 0·51); Denmark 0·60 (0·13, 1·08); and The Netherlands 1·46 (0·51, 2·72). There was no clear evidence that the risk of transmission or of clinical manifestations was lowest in centres with the most intensive prenatal treatment

Ben Barakat 'Ali

’Ali Ben Barakat, ou ’Ali Ou-Barka sous sa forme berbère, est un personnage historique, bien que quelque peu énigmatique. C’est surtout par le biais de l’hagiographie locale que l’on a pu réunir les quelques documents dont on dispose à son sujet (Drouin, 1975). Caïd makhzen des Ayt Yoummour sous Moulay Ismaïl, ’Ali Ou-Barka fit peser l’influence du pouvoir central de façon déterminante sur le pays des imaziγen à une époque où, entre la fin des Dilaïtes et l’émergence des Imhiwaš, la pression ..

Corrigendum to “Pollen-based paleoenvironmental and paleoclimatic change at Lake Ohrid (south-eastern Europe) during the past 500 ka” published in Biogeosciences, 13, 1423–1437, 2016

In this corrigendum we report an updated pollen record from the Lake Ohrid DEEP site spanning the past 500 ka whereby we have reprocessed and re-analyzed 104 samples affected by chemical procedure problems that occurred in one palynological laboratory. Firstly, these samples were affected by the use of wrong containers, causing in- adequate settling of particles at the set centrifuging speed. Secondly, HCl and HF treatments were combined without the prescribed intermediate centrifuging and decanting steps. The inaccuracy in the protocol resulted in the loss of smaller pollen grains and in the overrepresentation of bisaccate ones in most of the re-analyzed samples. We therefore provide an updated set of figures with the new data and have revised the description of the results, discussion and conclusions re- ported in Sadori et al. (2016) where necessary. We stress that the majority of the original results and conclusions remain valid, while the records’ reliability and resolution have improved as 12 samples that had been omitted in the original study because of low count sums are now included in the revised dataset (Sadori et al., 2018)

La valeur économique totale de la forêt méditerranéenne française.

À partir d'une importante collecte de données, cet article fournit une analyse étendue et une comparaison des valeurs économiques liées aux forêts françaises et méditerranéennes, incluant non seulement les valeurs aisément et traditionnellement mesurées comme la production de bois, mais aussi les biens publics et les externalités qu'elles engendrent. Ces valeurs estimées, placées dans le contexte institutionnel et politique qui régit la gestion forestière, peuvent contribuer à une meilleure prise en compte des différents enjeux et défis auxquels font face les forêts, dessinant de nouvelles approches de politique publique permettant d'accroître la provision de biens publics tout en réduisant les effets négatifs concomitants

Pollen-based temperature and precipitation changes in the Ohrid Basin (western Balkans) between 160 and 70 ka

Our study aims to reconstruct climate changes that occurred at Lake Ohrid (south-western Balkan Peninsula), the oldest extant lake in Europe, between 160 and 70&thinsp;ka (covering part of marine isotope stage 6, MIS 6; all of MIS 5; and the beginning of MIS 4). A multi-method approach, including the “Modern Analog Technique” and the “Weighted Averaging Partial Least-Squares Regression”, is applied to the high-resolution pollen sequence of the DEEP site, collected from the central part of Lake Ohrid, to provide quantitative estimates of climate and bioclimate parameters. This allows us to document climatic change during the key periods of MIS 6 and MIS 5 in southern Europe, a region where accurate climate reconstructions are still lacking for this time interval. Our results for the penultimate glacial show cold and dry conditions, while the onset of the “last interglacial” is characterized by wet and warm conditions, with temperatures higher than today (by ca. 2&thinsp;∘C). The Eemian also shows the well-known climatic tri-partition in the Balkans, with an initial pre-temperate phase of abrupt warming (128–121&thinsp;ka), a central temperate phase with decreasing temperatures associated with wet conditions (121–118&thinsp;ka), followed by a post-temperate phase of progressive change towards cold and dry conditions (118–112&thinsp;ka). After the Eemian, an alternation of four warm/wet periods with cold/dry ones, likely related to the succession of Greenland stadials and cold events known from the North Atlantic, occurred. The observed pattern is also consistent with hydrological and isotopic data from the central Mediterranean. The Lake Ohrid climate reconstruction shows greater similarity with climate patterns inferred from northern European pollen records than with southern European ones, which is probably due to its intermediate position and the mountainous setting. However, this hypothesis needs further testing as very few climate reconstructions are available for southern Europe for this key time period.</p

Quantitative reconstruction of climatic variations during the Bronze and early Iron ages based on pollen and lake-level data in the NW Alps, France

International audienceVegetation and lake-level data from the archaeological site of Tresserve, on the eastern shore of Lake Le Bourget (Savoie, France), are used to provide quantitative estimates of climatic variables over the period 4000-2300 cal BP in the northern French Pre-Alps, and to examine the possible impact of climatic changes on societies of the Bronze and early Iron Ages. The results obtained indicate that phases of higher lake level at 3500-3100 and 2750-2350 cal BP coincided with major climate reversals in the North Atlantic area. In west-central Europe, they were marked by cooler and wetter conditions. These two successive events may have affected ancient agricultural communities in west-central Europe by provoking harvest failures, more particularly due to increasing precipitation during the growing season. However, archaeological data in the region of Franche-Comté (Jura Mountains, eastern France) show a general expansion of population density from the middle Bronze Age to the early Iron Age. This suggests a relative emancipation of proto-historic societies from climatic conditions, probably in relation to the spread of new modes of social and economic organisation

Determining Sex in Golden Eagle (AQUILA CHRYSAETOS) Nestling

Incorporating sex ratios of nestlings into population viability studies increases knowledge of overall health of endangered populations. Currently, a reliable non-invasive method to identify the sex of golden eagle nestlings is not available; however, claims are commonly made based on morphology. Ten biometric measurements from 43 Scottish golden eagles aged 2–7.5 weeks were assessed to see if sex could actually be determined using this non-invasive methodology. Sex was confirmed via molecular analysis of blood samples. Discrete and principal component analyses of the different biometrics could not correctly determine individual nestling sex. Therefore, despite being more invasive, molecular sexing remains the recommended tool of choice for accurate sex identification of Scottish golden eagle nestlings younger than 7.5 weeks of age. This has important implications for golden eagle field studies where empirical morphological measurements are frequently and typically taken, but we have shown are not reliable in determining the sex of such young nestlings

Mid Holocene vegetation reconstruction from Vanevan peat (south-eastern shore of Lake Sevan, Armenia)

International audienceA sediment core has been retrieved from Vanevan peat (south-eastern shore of Lake Sevan, Armenia), which is today disconnected from Lake Sevan thanks to an artificial shallowing of the lake. Based on 5 radiocarbon dates, Vanevan record covers the Mid Holocene (from ca. 7800 to ca. 5100 cal. BP). The Late Holocene is today absent in the peat stratigraphy due to modern peat exploitation by surface mining. This study focuses on a multi-proxy approach including pollen, charcoals, and pollen-inferred climate reconstruction. An open-land, steppic vegetation is recorded up to ca. 7700 cal. BP, followed by a more forested landscape during the Mid Holocene (up to ca. 5700 cal. BP), and ending again with an open-land vegetation (to the end of record, 5100 cal. BP). This vegetation dynamics responds to general climate changes documented in the Near East. Whether human activities are documented since ca. 7500 cal. BP (Late Neolithic) in Vanevan, they remain marginal and probably did not affect the area. Early Holocene dry climate, which caused the steppic environment to be widespread through the Near East, is strongly related to low late spring precipitation (PMay–Jun = 180 mm). Mid Holocene forested landscape and increasing lake-level seem related to late spring precipitation (+28%), which is the main change in estimated climate parameters. This has to be linked with reinforcement of the Westerlies and less active Siberian High, which are inversely involved in the following, dry phase starting at ca. 5700 cal. B