A Statutory Remedy for Negligent Hiring in Deafness Rehabilitation

Given the modest gains in hiring well qualified deafness rehabilitation personnel in Vocational Rehabilitation, is it time to recognize that negligent hiring in deafness rehabilitation is a subtle form of discrimination against deaf and multiply handicapped deaf VR applicants? Amendments to the Rehabilitation Act are recommended to remedy the negligent hiring practices of some VR Rehabilitation of Deaf Clients (Schein, 1980) agencies that further disable deaf clients by hiring rehabilitation personnel who lack the skills to work effectively with deaf and multiply handicapped people

Strategies for Innovation and Sustainability: Insights from Leaders of Open Source Repository Organizations

4th International Conference on Open RepositoriesThis presentation was part of the session : Conference PresentationsThis panel convenes leaders of organizations that provide the major open repository software platforms featured at OR09. This session provides an opportunity to learn about the strategic processes behind the software - both from a technical and business perspective. The panelists will each provide an overview of their strategic approach open source and open repositories. Specific attention will be paid to strategies for promoting innovation, governance and organization models, and revenue and business models. The area of sustainability and business models for open source software is active and evolving and there is no one-size-fits-all solution. The panelists will discuss their views on ensuring the health and vitality of their platforms, addressing challenges such as: ensuring stability while promoting innovation; generating revenue; enabling community process, governance, and organizational development

Do ACE inhibitors or ARBs help prevent kidney disease in patients with diabetes and normal BP?

Q: Do ACE inhibitors or ARBs help prevent kidney disease in patients with diabetes and normal BP? Evidence-based answer: Yes for angiotensin-converting enzyme (ACE) inhibitors, no for angiotensin receptor blockers (ARBs). In normotensive patients with type 1 and type 2 diabetes, ACE inhibitor therapy reduces the risk of developing diabetic kidney disease, defined as new-onset microalbuminuria or macroalbuminuria, by 18% (strength of recommendation [SOR]: C, meta-analysis of randomized controlled trials [RCTs], disease-oriented evidence). ACE inhibitor treatment improves all-cause mortality by 16% in patients with diabetes, including patients with and without hypertension. Patients on ACE inhibitor therapy are at increased risk of cough (SOR: A, meta-analysis of RCTs). ARB therapy doesn't lower the risk of developing kidney disease in normotensive patients with type 2 diabetes (SOR: C, meta-analysis of RCTs, disease-oriented evidence); nor does it reduce all-cause mortality in patients with or without hypertension (SOR: A, meta-analysis of RCTs). ARBs aren't associated with significant adverse events (SOR: A, meta-analysis of RCTs)

Functional disability and social participation restriction associated with chronic conditions in middle-aged and older adults

Abstract : Background. We examine the population impact on functional disability and social participation of physical and mental chronic conditions individually and in combination. Methods. Cross-sectional, population-based data from community-dwelling people aged 45 years and over living in the 10 Canadian provinces in 2008–2009 were used to estimate the population attributable risk (PAR) for functional disability in basic (ADL) and instrumental (IADL) activities of daily living and social participation restrictions for individual and combinations of chronic conditions, stratified by age and gender, after adjusting for confounding variables. Results. Five chronic conditions (arthritis, depression, diabetes, heart disease and eye disease) made the largest contributions to ADL-related and IADL-related functional disability and social participation restrictions, with variation in magnitude and ranking by age and gender. While arthritis was consistently associated with higher PARs across gender and most age groups, depression, alone and in combination with the physical chronic conditions, was associated with ADL and IADL disability as well as social participation restrictions in the younger age groups, especially among women. Compared to women, the combinations of conditions associated with higher PARs in men more often included heart disease and diabetes. Conclusions. Our findings suggest that in community dwelling middle-aged and older adults, the impact of combinations of mental and physical chronic conditions on functional disability and social participation restriction is substantial and differed by gender and age. Recognising the differences in the drivers of PAR by gender and age group will ultimately increase the efficiency of clinical and public health interventions

Serum Concentrations of Myostatin and Myostatin-Interacting Proteins do not differ between young and Scarcopenic elderly men

Peer reviewedPostprin

3D T2w fetal body MRI:automated organ volumetry, growth charts and population-averaged atlas

Structural fetal body MRI provides true 3D information required for volumetry of fetal organs. However, current clinical and research practice primarily relies on manual slice-wise segmentation of raw T2-weighted stacks, which is time consuming, subject to inter- and intra-observer bias and affected by motion-corruption. Furthermore, there are no existing standard guidelines defining a universal approach to parcellation of fetal organs. This work produces the first parcellation protocol of the fetal body organs for motion-corrected 3D fetal body MRI. It includes 10 organ ROIs relevant to fetal quantitative volumetry studies. We also introduce the first population-averaged T2w MRI atlas of the fetal body. The protocol was used as a basis for training of a neural network for automated organ segmentation. It showed robust performance for different gestational ages. This solution minimises the need for manual editing and significantly reduces time. The general feasibility of the proposed pipeline was also assessed by analysis of organ growth charts created from automated parcellations of 91 normal control 3T MRI datasets that showed expected increase in volumetry during 22-38 weeks gestational age range. In addition, the results of comparison between 60 normal and 12 fetal growth restriction datasets revealed significant differences in organ volumes.</p

Can forest management based on natural disturbances maintain ecological resilience?

Given the increasingly global stresses on forests, many ecologists argue that managers must maintain ecological resilience: the capacity of ecosystems to absorb disturbances without undergoing fundamental change. In this review we ask: Can the emerging paradigm of natural-disturbance-based management (NDBM) maintain ecological resilience in managed forests? Applying resilience theory requires careful articulation of the ecosystem state under consideration, the disturbances and stresses that affect the persistence of possible alternative states, and the spatial and temporal scales of management relevance. Implementing NDBM while maintaining resilience means recognizing that (i) biodiversity is important for long-term ecosystem persistence, (ii) natural disturbances play a critical role as a generator of structural and compositional heterogeneity at multiple scales, and (iii) traditional management tends to produce forests more homogeneous than those disturbed naturally and increases the likelihood of unexpected catastrophic change by constraining variation of key environmental processes. NDBM may maintain resilience if silvicultural strategies retain the structures and processes that perpetuate desired states while reducing those that enhance resilience of undesirable states. Such strategies require an understanding of harvesting impacts on slow ecosystem processes, such as seed-bank or nutrient dynamics, which in the long term can lead to ecological surprises by altering the forest's capacity to reorganize after disturbance

Measurement of Deeply Virtual Compton Scattering Off \u3csup\u3e4\u3c/sup\u3eHe with the CEBAF Large Acceptance Spectrometer at Jefferson Lab

We report on the measurement of the beam spin asymmetry in the deeply virtual Compton scattering off 4He using the CEBAF Large Acceptance Spectrometer (CLAS) at Jefferson Lab using a 6 GeV longitudinally polarized electron beam incident on a pressurized 4He gaseous target. We detail the method used to ensure the exclusivity of the measured reactions, in particular the upgrade of CLAS with a radial time projection chamber to detect the low-energy recoiling 4He nuclei and an inner calorimeter to extend the photon detection acceptance at forward angles. Our results confirm the theoretically predicted enhancement of the coherent (e4He→e′4Heγ′) beam spin asymmetries compared to those observed on the free proton, while the incoherent (e4He→ e′p′γ′X′) asymmetries exhibit a 30% suppression. From the coherent data, we were able to extract, in a model-independent way, the real and imaginary parts of the only 4He Compton form factor, HA, leading the way toward 3D imaging of the partonic structure of nuclei