446 research outputs found
Self consistent kinetic simulations of SPT and HEMP thrusters including the near-field plume region
The Particle-in-Cell (PIC) method was used to study two different ion
thruster concepts - Stationary Plasma Thrusters (SPT) and High Efficiency
Multistage Plasma Thrusters (HEMP-T), in particular the plasma properties in
the discharge chamber due to the different magnetic field configurations.
Special attention was paid to the simulation of plasma particle fluxes on the
thrusters channel surfaces. In both cases, PIC proved itself as a powerful
tool, delivering important insight into the basic physics of the different
thruster concepts. The simulations demonstrated that the new HEMP thruster
concept allows for a high thermal efficiency due to both minimal energy
dissipation and high acceleration efficiency. In the HEMP thruster the plasma
contact to the wall is limited only to very small areas of the magnetic field
cusps, which results in much smaller ion energy flux to the thruster channel
surface as compared to SPT. The erosion yields for dielectric discharge channel
walls of SPT and HEMP thrusters were calculated with the binary collision code
SDTrimSP. For SPT, an erosion rate on the level of 1 mm of sputtered material
per hour was observed. For HEMP, thruster simulations have shown that there is
no erosion inside the dielectric discharge channel.Comment: 14 pages, 11 figures This work was presented at 21st International
Conference on Numerical Simulation of Plasmas (ICNSP'09
Radio-frequency discharges in Oxygen. Part 1: Modeling
In this series of three papers we present results from a combined
experimental and theoretical effort to quantitatively describe capacitively
coupled radio-frequency discharges in oxygen. The particle-in-cell Monte-Carlo
model on which the theoretical description is based will be described in the
present paper. It treats space charge fields and transport processes on an
equal footing with the most important plasma-chemical reactions. For given
external voltage and pressure, the model determines the electric potential
within the discharge and the distribution functions for electrons, negatively
charged atomic oxygen, and positively charged molecular oxygen. Previously used
scattering and reaction cross section data are critically assessed and in some
cases modified. To validate our model, we compare the densities in the bulk of
the discharge with experimental data and find good agreement, indicating that
essential aspects of an oxygen discharge are captured.Comment: 11 pages, 10 figure
Comparative study of semiclassical approaches to quantum dynamics
Quantum states can be described equivalently by density matrices, Wigner
functions or quantum tomograms. We analyze the accuracy and performance of
three related semiclassical approaches to quantum dynamics, in particular with
respect to their numerical implementation. As test cases, we consider the time
evolution of Gaussian wave packets in different one-dimensional geometries,
whereby tunneling, resonance and anharmonicity effects are taken into account.
The results and methods are benchmarked against an exact quantum mechanical
treatment of the system, which is based on a highly efficient Chebyshev
expansion technique of the time evolution operator.Comment: 32 pages, 8 figures, corrected typos and added references; version as
publishe
On the Wake Structure in Streaming Complex Plasmas
The theoretical description of complex (dusty) plasmas requires multiscale
concepts that adequately incorporate the correlated interplay of streaming
electrons and ions, neutrals, and dust grains. Knowing the effective dust-dust
interaction, the multiscale problem can be effectively reduced to a
one-component plasma model of the dust subsystem. The goal of the present
publication is a systematic evaluation of the electrostatic potential
distribution around a dust grain in the presence of a streaming plasma
environment by means of two complementary approaches: (i) a high precision
computation of the dynamically screened Coulomb potential from the dynamic
dielectric function, and (ii) full 3D particle-in-cell simulations, which
self-consistently include dynamical grain charging and non-linear effects. The
applicability of these two approaches is addressed
Детектирование индуцированных тепловым потоком напряжений в твердом теле с помощью фотоупругого микроскопа
Мета цієї статті полягає в представленні переваг практичного та ефективного методу модуляційної поляриметрії (МПМ), застосованого до зразка кварцового скла у вигляді пластини для виявлення його найменших внутрішніх термонапружень, викликаних поширення теплової хвилі. Описаний МПМ дозволив провести точні вимірювання двопроменезаломлення, яке супроводжує динаміку термопружності, що зробило можливим обчислення значення розподілу напружень вздовж і поперек напрямку теплового потоку в певні моменти часу, а також їх залежність від часу в певних координатах теплового потоку. Основна мета даної роботи є не тільки вирішення обернених задач нестаціонарної термопружності, що дозволяє отримати просторово-часові температурні функції графічним інтегруванням експериментальних характеристик, але й дослідження динаміки точки максимуму кривизни температурної функції T(t), що є характеристикою теплового фронту в процесі встановлення теплового потоку. Окрім того, було показано, що завдяки високій виявній здатності МПМ застосованої у фотопружному мікроскопі, стало можливим спостерігати радіаційну складову теплопереносу.The aim of this paper is to present adventures of practical and effective modulation polarimetry method (MPM) applied to the plate sample of quartz glass for detection of its minute internal thermoelastic stresses induced by heat wave propagation. Described MPM allowed to make accurate measuring of birefringence that accompany the dynamics of thermoelasticity and made possible to calculate the value of stress distribution along and crosswise to the direction of heat flow at certain moments of time, as well as its dependence on time in defined heat flux coordinates. The main goal of this paper is not only the solution of inverse problems of nonstationary thermoelasticity that allowed obtaining spatio-temporal temperature functions by graphical integration of the experimental characteristics but researching the dynamics of the maximum curvature point of the temperature function T(t) that is a characteristic of the thermal front in the process of heat flow establishment. In addition, it is shown that due to the high detectability of MPM applied in photoelastic microscope became possible to observe the radiation component of the heat transfer process.Цель этой статьи заключается в представлении преимуществ практического и эффективного метода модуляционной поляриметрии (МПМ), примененного к образцу кварцевого стекла в виде пластины для выявления его самых малых внутренних термонапряжений, вызванных распространением тепловой волны. Описанный МПМ позволил провести точные измерения двулучепреломления, которое сопровождает динамику термоупругости, что сделало возможным вычисление значения распределения напряжений вдоль и поперек направления теплового потока в определенные моменты времени, а также их зависимость от времени в определенных координатах теплового потока. Основная цель данной работы является не только решение обратной задачи нестационарной термоупругости, что позволяет получить пространственно-временные температурные функции графическим интегрированием экспериментальных характеристик, но и исследование динамики точки максимума кривизны температурной функции T(t), что является характеристикой теплового фронта в процессе установления теплового потока. Кроме того, было показано, что благодаря применению высокой обнаружительной способности МПМ в фотоупругом микроскопе сделало возможным наблюдать радиационную составляющую теплопереноса
Computation of dust charge and potential on a static spherical dust grain immersed in rf discharges
Employing an open-source tool to assess astrocyte tridimensional structure
Astrocytes display important features that allow them to maintain a close dialog with neurons, ultimately impacting brain function. The complex morphological structure of astrocytes is crucial to the role of astrocytes in brain networks. Therefore, assessing morphologic features of astrocytes will help provide insights into their physiological relevance in healthy and pathological conditions. Currently available tools that allow the tridimensional reconstruction of astrocytes present a number of disadvantages, including the need for advanced computational skills and powerful hardware, and are either time-consuming or costly. In this study, we optimized and validated the FIJI-ImageJ, Simple Neurite Tracer (SNT) plugin, an open-source software that aids in the reconstruction of GFAP-stained structure of astrocytes. We describe (1) the loading of confocal microscopy Z-stacks, (2) the selection criteria, (3) the reconstruction process, and (4) the post-reconstruction analysis of morphological features (process length, number, thickness, and arbor complexity). SNT allows the quantification of astrocyte morphometric parameters in a simple, efficient, and semi-automated manner. While SNT is simple to learn, and does not require advanced computational skills, it provides reproducible results, in different brain regions or pathophysiological states.The authors acknowledge funding from national funds through the FCT—Foundation for Science and Technology—project (PTDC/SAU-NSC/118194/2010) to G.T., V.M.S., S.G.G. and J.F.O., and fellowships (SFRH/BD/89714/2012 to V.M.S., SFRH/BPD/97281/2013 to J.F.O., SFRH/BD/101298/2014 to S.G.G., PD/BD/114120/2015 to S.P.N, and PD/BD/127822/2016 to G.T.); Marie Curie Fellowship FP7-PEOPLE-2010-IEF 273936 and BIAL Foundation Grants and 207/14 to J.F.O.; QREN and FEDER funds through Operational program for competitiveness factors—COMPETE, “ON.2 SR&TD Integrated Program—NORTE-07-0124-FEDER-000021”; National and European funds through FCT, and FEDER through COMPETE (PEst-C/SAU/LA0026/2011 and FCOMP-01-0124-FEDER-022724; PEst-C/SAU/LA0026/2013 and FCOMP-01-0124-FEDER-037298, respectively)info:eu-repo/semantics/publishedVersio
The role of thermal energy accommodation and atomic recombination probabilities in low pressure oxygen plasmas
International audienceSurface interaction probabilities are critical parameters that determine the behaviour of low pressure plasmas and so are crucial input parameters for plasma simulations that play a key role in determining their accuracy. However, these parameters are difficult to estimate without in situ measurements. In this work, the role of two prominent surface interaction probabilities, the atomic oxygen recombination coefficient ? O and the thermal energy accommodation coefficient ? E in determining the plasma properties of low pressure inductively coupled oxygen plasmas are investigated using two-dimensional fluid-kinetic simulations. These plasmas are the type used for semiconductor processing. It was found that ? E plays a crucial role in determining the neutral gas temperature and neutral gas density. Through this dependency, the value of ? E also determines a range of other plasma properties such as the atomic oxygen density, the plasma potential, the electron temperature, and ion bombardment energy and neutral-to-ion flux ratio at the wafer holder. The main role of ? O is in determining the atomic oxygen density and flux to the wafer holder along with the neutral-to-ion flux ratio. It was found that the plasma properties are most sensitive to each coefficient when the value of the coefficient is small causing the losses of atomic oxygen and thermal energy to be surface interaction limited rather than transport limited
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Investigating mechanisms underpinning the detrimental impact of a high-fat diet in the developing and adult hypermuscular myostatin null mouse
Background: Obese adults are prone to develop metabolic and cardiovascular diseases. Furthermore, over-weight expectant mothers give birth to large babies who also have increased likelihood of developing metabolic and cardiovascular diseases. Fundamental advancements to better understand the pathophysiology of obesity are critical in the development of anti-obesity therapies not only for this but also future generations. Skeletal muscle plays a major role in fat metabolism and much work has focused in promoting this activity in order to control the development of obesity. Research has evaluated myostatin inhibition as a strategy to prevent the development of obesity and concluded in some cases that it offers a protective mechanism against a high-fat diet.
Results: We hypothesised that myostatin inhibition should protect not only the mother but also its developing foetus from the detrimental effects of a high-fat diet. Unexpectedly, we found muscle development was attenuated in the foetus of myostatin null mice raised on a high-fat diet. We therefore re-examined the effect of the high-fat diet on adults and found myostatin null mice were more susceptible to diet-induced obesity through a mechanism involving impairment of inter-organ fat utilization.
Conclusions: Loss of myostatin alters fatty acid uptake and oxidation in skeletal muscle and liver. We show that abnormally high metabolic activity of fat in myostatin null mice is decreased by a high-fat diet resulting in excessive adipose deposition and lipotoxicity. Collectively, our genetic loss-of-function studies offer an explanation of the lean phenotype displayed by a host of animals lacking myostatin signalling.
Keywords: Muscle, Obesity, High-fat diet, Metabolism, Myostati
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