Spectrum of the Relativistic Particles in Various Potentials

We extend the notion of Dirac oscillator in two dimensions, to construct a set of potentials. These potentials becomes exactly and quasi-exactly solvable potentials of non-relativistic quantum mechanics when they are transformed into a Schr\"{o}dinger-like equation. For the exactly solvable potentials, eigenvalues are calculated and eigenfunctions are given by confluent hypergeometric functions. It is shown that, our formulation also leads to the study of those potentials in the framework of the supersymmetric quantum mechanics

Identificación Automática de Idioma en Lenguaje Hablado

La identificación automática de idioma (LID) es la tarea por la cual se ha de reconocer en qué idioma se está hablando en una conversación. Podemos encontrar dos problemas típicos: identificación, donde decidiremos el idioma de entre un conjunto conocido de posibilidades; o detección, donde decidiremos si la conversación se habla o no en un idioma objetivo. Las utilidades principales son el enrutamiento de llamadas en call-centers, audiodescripción, y seguridad militar. Las principales técnicas utilizadas se dividen en tres grupos: a) técnicas acústicas: se extraen las características frecuenciales a corto plazo de la señal, principalmente mediante los mel frequency cepstral coefficients (MFCC); b) técnicas basadas en tokens: se particiona la señal en grupos preestablecidos (tokens) y se estudian las frecuencias y el orden de aparición de los mismos, como en el reconocimiento de fonemas seguido de modelo de lenguaje (PRLM), donde los tokens son fonemas; c) técnicas prosódicas: se extraen características suprasegmentales de la señal a largo plazo, como el pitch, la energía, la duración o los formantes. Una vez extraídos uno o varios de estos parámetros, se utilizan técnicas de reconocimiento de patrones para formar modelos de cada idioma, con los que realizaremos la clasificación. Nuestro grupo está investigando principalmente técnicas acústicas y prosódicas, utilizando clasificadores basados en iVectors, basados a su vez en factor analysis. Para comparar las prestaciones entre diferentes grupos de investigación se realizan evaluaciones a nivel nacional e internacional, con idiomas muy variados, donde nuestro grupo ha obtenido muy buenos resultados en las últimas ediciones

Asignación de docentes a establecimientos educativos: un enfoque multi-objetivo

Contar con una adecuada planificación logística contribuye a mejorar el funcionamiento del sistema educativo, impactando positivamente las condiciones asociadas al aprendizaje. Este trabajo propone una nueva formulación matemática del problema de Asignación de Docentes a Establecimientos Educativos (ADEE), con un enfoque multi-objetivo para: (1) minimizar la distancia entre la residencia del docente y el establecimiento educativo, (2) maximizar la cantidad de docentes asignados al mismo establecimiento educativo y (3) maximizar la cantidad de clases dictadas por un docente en diferentes turnos. Para resolver la formulación propuesta se presenta un Algoritmo Evolutivo Multi-Objetivo (MOEA) basado en el NSGA-II. Resultados experimentales con datos reales del Departamento de Alto Paraná del Ministerio de Educación y Ciencias (MEC) de Paraguay con 457 establecimientos educativos, 2995 clases y 1808 docentes, indican mejoras significativas en la asignación.XXI Workshop Tecnología Informática aplicada en Educación (WTIAE)Red de Universidades con Carreras en Informátic

Intradermal and virosomal influenza vaccines for preventing influenza hospitalization in the elderly during the 2011–2012 influenza season: A comparative effectiveness study using the Valencia health care information system

AbstractBackgroundThe use of intradermal vaccination or virosomal vaccines could increase protection against influenza among the vulnerable population of older adults. Studies assessing the comparative effectiveness of these two influenza vaccine types in this age group are lacking.MethodsWe conducted a retrospective cohort study to estimate the comparative effectiveness of intradermal seasonal trivalent-influenza vaccine (TIV) delivered by a microneedle injection system and a virosomal-TIV intramuscularly delivered for prevention of influenza hospitalization in non-institutionalized adults aged ≥65 years. We obtained administrative data on immunization status and influenza hospitalization for the 2011–2012 influenza season, and used Cox regression models to assess comparative effectiveness. We estimated crude and adjusted (age, sex, comorbidity, pharmaceutical claims, recent pneumococcal vaccination and number of hospitalizations for all causes other than influenza between the previous and current influenza seasons) hazard ratios (HR).ResultsOverall, 164,021 vaccinated subjects were evaluated. There were 127 hospitalizations for influenza among 62,058 subjects, contributing 914,740 person-weeks at risk in the virosomal-TIV group, and 133 hospitalizations for influenza among 101,963 subjects, contributing 1,504,570 person-weeks at risk in the intradermal-TIV group. The crude HR of intradermal-TIV relative to virosomal-TIV was 0.64 (95% confidence interval (CI): 0.50–0.81), and the adjusted Cox estimated HR was 0.67 (95% CI: 0.52–0.85).ConclusionsDuring the 2011–2012 influenza season the risk of hospitalization for influenza was reduced by 33% in non-institutionalized elderly adults who were vaccinated with intradermal-TIV compared with virosomal-TIV

Evolución de las licencias federativas de pádel en Andalucía (2009-2016)

The last years of sport in Spain show a high growth in the practice of paddle (Gómez-Chacón, Pascua-Barón and Fernández-Martínez, 2017). The paddle, is the sport of racket more practiced weekly by the Spanish population (Superior Council of Sports, 2015). Likewise, and following the line of other authors, paddle is the sport that has most developed in the last 23 years with a growth of 1,947.41% (López, 2017). The objective of this study is to know the evolution of the federative paddle licenses in Andalusia in absolute category during the years 2009-2016 in order to certify that all the data found coincide with what various authors and public bodies have affirmed. The database of the Andalusian federation of Paddle was consulted. All the data extracted in the consulted bibliography do not do more than indicate that the paddle is one of the most emergent sports and with greater growth of the XXI century.Los últimos años del deporte en España muestran un alto crecimiento en la práctica del pádel (Gómez-Chacón, Pascua-Barón y Fernández–Martínez, 2017). El pádel, es el deporte de raqueta más practicado semanalmente por la población Española(Consejo Superior de Deportes, 2015).Asimismo, y siguiendo la línea de otros autores, el pádel, es el deporte que más se ha desarrollado en los últimos 23 años con un crecimiento del 1.947,41% (López, 2017).El objetivo de este estudio es conocer la evolución de las licencias federativas de pádel en Andalucía durante los años 2009-2016, para poder certificar que todos los datos encontrados coinciden con lo que han afirmado diversos autores y organismos públicos. Se consultó la base de datos de la federación Andaluza de Pádel. Todos los datos extraídos en la bibliografía consultada no hacen más que indicar que el pádel es uno de los deportes más emergentes y con mayor crecimiento y evolución del siglo XXI

Genetic markers associated with divergent selection against the parasite Marteilia cochillia in common cockle (Cerastoderma edule) using transcriptomics and population genomics data

The common cockle (Cerastoderma edule) plays an important role in marine ecosystems and represents a valuable socioeconomic resource for coastal communities. In 2012, the cockle beds from Rı́a de Arousa (Galicia, NW Spain) were seriously decimated by the protozoan Marteilia cochillia responsible for marteiliosis. We aimed to identify single nucleotide polymorphisms (SNP) markers potentially associated with resilience to marteiliosis to be used in marker-assisted selection programs for restoring affected cockle beds and recovering their production. For this, we carried out a population genomics approach using 2b-RADseq, where 38 naive samples (before the first detection of M. cochillia in 2012) from two beds of Rı́a de Arousa were compared with 39 affected samples collected in 2018/2019 (after several years of marteiliosis occurring in the area), collected either before (15 non-exposed samples) or during (24 exposed samples) the marteiliosis outbreak. Additionally, 767 differentially expressed genes (DEG) from a previous transcriptomic study addressed during the aforementioned 2018/19 marteiliosis outbreak, were evaluated to identify SNPs showing signals of selection. Using 2b-RADseq, 9,154 SNPs were genotyped and among them, 110 consistent outliers for divergent selection were identified. This set of SNPs was able to discriminate the samples according to their marteiliosis status (naive vs affected; exposed vs non-exposed), while another 123 SNPs were identified linked to DEGs associated with the level of infection across a temporal series. Finally, combining the population genomics and transcriptomics information, we selected the 60 most reliable SNPs associated with marteiliosis resilience. These SNPs were close to or within DEGs, and many of them were related to immune response (phagocytosis and cell adhesion), defence, such as apoptosis, stress, and cellular cycle, among other functions. This set of SNPs will eventually be validated to develop a cost-effective genotyping tool for their application for obtaining cockle-resilient strains for marteiliosis

Lecciones aprendidas del terremoto de Lorca de 2011.

El terremoto de Lorca del 11 de mayo de 2011, de magnitud Mw=5,2, causó un enorme impacto en la ciudad y una gran alarma social, provocando 9 víctimas mortales, centenares de heridos y cuantiosos daños materiales. Este trabajo recoge las opiniones de varios expertos que tuvieron un papel destacado en la gestión y análisis del suceso, y la de 627 lorquinos a través de una encuesta llevada a cabo por estudiantes del I.E.S. Ramón Arcas de Lorca. Aunque cada uno de los expertos y los ciudadanos inciden en aspectos diferentes, el análisis de sus opiniones nos permite concluir, como principal lección aprendida, que terremotos futuros como el de Lorca pueden producir muchos menos daños si se trabaja conjuntamente en mejorar: (1) la investigación sísmica, (2) la calidad de las construcciones, (3) la gestión de las catástrofes naturales y (4) la formación de la ciudadanía. Esta aproximación multidisciplinar al terremoto de Lorca puede resultar interesante para los estudiantes, y puede aportar ideas a los docentes para el análisis de futuros terremotos

V2X-d: a Vehicular Density Estimation System that combines V2V and V2I Communications

© 2013 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.Road traffic is experiencing a drastic increase, and vehicular traffic congestion is becoming a major problem, especially in metropolitan environments throughout the world. Additionally, in modern Intelligent Transportation Systems (ITS) communications, the high amount of information that can be generated and processed by vehicles will significantly increase message redundancy, channel contention, and message collisions, thus reducing the efficiency of message dissemination processes. In this work, we present a V2X architecture to estimate traffic density on the road that relies on the advantages of combining V2V and V2I communications. Our proposal uses both the number of beacons received per vehicle (V2V) and per RSU (V2I), as well as the roadmap topology features to estimate the vehicle density. By using our approach, modern Intelligent Transportation Systems will be able to reduce traffic congestion and also to adopt more efficient message dissemination protocols.This work was partially supported by the Ministerio de Ciencia e Innovación, Spain, under Grant TIN2011-27543-C03-01, by the Fundación Universitaria Antonio Gargallo and the Obra Social de Ibercaja, under Grant 2013/B010, as well as the Government of Aragón and the European Social Fund (T91 Research Group).Barrachina Villalba, J.; Sangüesa, JA.; Fogue, M.; Garrido, P.; Martínez, FJ.; Cano Escribá, JC.; Tavares De Araujo Cesariny Calafate, CM.... (2013). V2X-d: a Vehicular Density Estimation System that combines V2V and V2I Communications. IEEE. https://doi.org/10.1109/WD.2013.6686518

Mutations in the ND2 subunit of mitochondrial complex I are sufficient to confer increased tumorigenic and metastatic potential to cancer cells

Multiprotein complexes of the mitochondrial electron transport chain form associations to generate supercomplexes. The relationship between tumor cell ability to assemble mitochondrial supercomplexes, tumorigenesis and metastasis has not been studied thoroughly. The mitochondrial and metabolic differences between L929dt cells, which lost matrix attachment and MHC-I expression, and their parental cell line L929, were analyzed. L929dt cells have lower capacity to generate energy through OXPHOS and lower respiratory capacity than parental L929 cells. Most importantly, L929dt cells show defects in mitochondrial supercomplex assembly, especially in those that contain complex I. These defects correlate with mtDNA mutations in L929dt cells at the ND2 subunit of complex I and are accompanied by a glycolytic shift. In addition, L929dt cells show higher in vivo tumorigenic and metastatic potential than the parental cell line. Cybrids with L929dt mitochondria in L929 nuclear background reproduce all L929dt properties, demonstrating that mitochondrial mutations are responsible for the aggressive tumor phenotype. In spite of their higher tumorigenic potential, L929dt or mitochondrial L929dt cybrid cells are sensitive both in vitro and in vivo to the PDK1 inhibitor dichloroacetate, which favors OXPHOS, suggesting benefits for the use of metabolic inhibitors in the treatment of especially aggressive tumors