Diavideos: a Diabetes Health Video Portal

Diavideos1 is a web platform that collects trustworthy diabetes health videos from YouTube and offers them in a easy way. YouTube is a big repository of health videos, but good content is sometimes mixed with misleading and harmful videos such as promoting anorexia [1].Diavideos is a web portal that provides easy access to a repository of trustworthy diabetes videos. This poster describes Diavideos and explains the crawling method used to retrieve these videos from trusted channels

Radiation heat savings in polysilicon production: validation of results through a CVD laboratory prototype

This work aims at a deeper understanding of the energy loss phenomenon in polysilicon production reactors by the so-called Siemens process. Contributions to the energy consumption of the polysilicon deposition step are studied in this paper, focusing on the radiation heat loss phenomenon. A theoretical model for radiation heat loss calculations is experimentally validated with the help of a laboratory CVD prototype. Following the results of the model, relevant parameters that directly affect the amount of radiation heat losses are put forward. Numerical results of the model applied to a state-of-the-art industrial reactor show the influence of these parameters on energy consumption due to radiation per kilogram of silicon produced; the radiation heat loss can be reduced by 3.8% when the reactor inner wall radius is reduced from 0.78 to 0.70 m, by 25% when the wall emissivity is reduced from 0.5 to 0.3, and by 12% when the final rod diameter is increased from 12 to 15 cm

Withdrawal of dietary phytoestrogens in adult male rats affects hypothalamic regulation of food intake, induces obesity and alters glucose metabolism

The absence of phytoestrogens in the diet during pregnancy has been reported to result in obesity later in adulthood. We investigated whether phytoestrogen withdrawal in adult life could alter the hypothalamic signals that regulate food intake and affect body weight and glucose homeostasis. Male Wistar rats fed from conception to adulthood with a high phytoestrogen diet were submitted to phytoestrogen withdrawal by feeding a low phytoestrogen diet, or a high phytoestrogen-high fat diet. Withdrawal of dietary phytoestrogens increased body weight, adiposity and energy intake through an orexigenic hypothalamic response characterized by upregulation of AGRP and downregulation of POMC. This was associated with elevated leptin and T4, reduced TSH, testosterone and estradiol, and diminished hypothalamic ERα expression, concomitant with alterations in glucose tolerance. Removing dietary phytoestrogens caused manifestations of obesity and diabetes that were more pronounced than those induced by the high phytoestrogen-high fat diet intake

Guinea-pig interpubic joint (symphysis pubica) relaxation at parturition: Underlying cellular processes that resemble an inflammatory response

BACKGROUND: At term, cervical ripening in coordination with uterine contractions becomes a prerequisite for a normal vaginal delivery. Currently, cervical ripening is considered to occur independently from uterine contractions. Many evidences suggest that cervical ripening resembles an inflammatory process. Comparatively little attention has been paid to the increased flexibility of the pelvic symphysis that occurs in many species to enable safe delivery. The aim of this study was to investigate whether the guinea-pig interpubic joint relaxation process observed during late pregnancy and parturition resembles an inflammatory process. METHODS: Samples of pubic symphysis were taken from pregnant guinea-pigs sacrificed along gestation, parturition and postpartum. Serial sections of paraffin-embedded tissues were used to measure the interpubic distance on digitalized images, stained with Giemsa to quantify leukocyte infiltration and to describe the vascular area changes, or studied by the picrosirius-polarization method to evaluate collagen remodeling. P4 and E2 serum levels were measured by a sequential immunometric assay. RESULTS: Data showed that the pubic relaxation is associated with an increase in collagen remodeling. In addition, a positive correlation between E2 serum levels and the increase in the interpubic distance was found. On the other hand, a leukocyte infiltration in the interpubic tissue around parturition was described, with the presence of almost all inflammatory cells types. At the same time, histological images show an increase in vascular area (angiogenesis). Eosinophils reached their highest level immediately before parturition; whereas for the neutrophilic and mononuclear infiltration higher values were recorded one day after parturition. Correlation analysis showed that eosinophils and mononuclear cells were positively correlated with E2 levels, but only eosinophilic infiltration was associated with collagen remodeling. Additionally, we observed typical histological images of dissolution of the connective tissue matrix around eosinophils. CONCLUSION: The present study shows that a timely regulated influx of infiltrating leukocytes is associated with an extensive collagen remodeling process that allows the pubic separation for a normal delivery in guinea-pig. Thus, the findings in this study support the hypothesis that the guinea-pig pubic symphyseal relaxation at parturition resembles an inflammatory process

Heart rate variability to assess ventilatory thresholds in professional basketball players

AbstractPurposeThe aim of this study was to determine if heart rate variability (HRV) during incremental test could be used to estimate ventilatory threshold (VT) in professional basketball players, with sufficient precision to be used in their training. Furthermore, the second aim was to analyse the association between HRV and three methods of VT determination by gas analysis.MethodsTwenty-four professional basketball players (age: 23.4 ± 4.9 years; height: 195.4 ± 9.8 cm; body mass: 92.2 ± 11.9 kg) performed an incremental running test to exhaustion. First ventilatory threshold (VT1) was determined by ventilatory equivalent (VE) and HRV and second ventilatory threshold (VT2) was determined by three methods of gases analysis (V-slope, VE and gas exchange ratio (R), and HRV). Pearson's coefficient (r) was used to detect differences between data and the strength of each relationship. The mean of absolute differences and Bland–Altman analysis were used to evaluate whether there was agreement.ResultsThe results showed no significant differences in HR and oxygen consumption (VO2) at VT1 between the two methods. Furthermore, no significant differences among the methods of gases analysis and HRV were observed in speed, HR, and VO2 at VT2. Moreover, VTs estimated using HRV and gas methods were significantly correlated. Correlation was higher between R and HRV (r = 0.96) and VE and HRV (r = 0.96) than V-slope and HRV (r = 0.90).ConclusionThese findings provide a practical, inexpensive approach for evaluating specific training loads when determining VT2 in basketball players. Therefore, HRV is an alternative method to determine VT2 without the application of expensive technology that limits its use to laboratories

Dietary Intervention Modulates the Expression of Splicing Machinery in Cardiovascular Patients at High Risk of Type 2 Diabetes Development: From the CORDIOPREV Study

Type-2 diabetes mellitus (T2DM) has become a major health problem worldwide. T2DM risk can be reduced with healthy dietary interventions, but the precise molecular underpinnings behind this association are still incompletely understood. We recently discovered that the expression profile of the splicing machinery is associated with the risk of T2DM development. Thus, the aim of this work was to evaluate the influence of 3-year dietary intervention in the expression pattern of the splicing machinery components in peripheral blood mononuclear cells (PBMCs) from patients within the CORDIOPREV study. Expression of splicing machinery components was determined in PBMCs, at baseline and after 3 years of follow-up, from all patients who developed T2DM (Incident-T2DM, n = 107) and 108 randomly selected non-T2DM subjects, who were randomly enrolled in two healthy dietary patterns (Mediterranean or low-fat diets). Dietary intervention modulated the expression of key splicing machinery components (i.e., up-regulation of SPFQ/RMB45/RNU6, etc., down-regulation of RNU2/SRSF6) after three years, independently of the type of healthy diet. Some of these changes (SPFQ/RMB45/SRSF6) were associated with key clinical features and were differentially induced in Incident-T2DM patients and non-T2DM subjects. This study reveals that splicing machinery can be modulated by long-term dietary intervention, and could become a valuable tool to screen the progression of T2DM

Spatio temporal and climatic analysis of the high Andean wetland of Chalhuanca (Peru) during the period 1986-2016

[ES] Los humedales altoandinos son considerados ecosistemas frágiles que proporcionan servicios ecosistémicos para el mantenimiento de la biodiversidad y economía andina, sin embargo, actualmente la amenaza global del cambio climático los pone en grave riesgo, es por ello que el objetivo de este estudio es determinar la variación espacio temporal y climática del humedal altoandino de Chalhuanca (Perú), durante el periodo 1986-2016. Se obtuvieron escenas Landsat de la temporada seca de los años 1986, 1991, 1996, 2001, 2006, 2011, 2016 y mediante técnicas de teledetección se calculó el área y el índice de vegetación (NDVI) de los humedales. Para la precipitación, temperatura máxima y temperatura mínima, se realizó un análisis de medias móviles, tendencias lineales y se aplicó la prueba estadística no paramétrica de Mann-Kendall, finalmente mediante correlación y regresión se evaluó la interacción entre las variables. Los resultados muestran que el área de humedal se ha incrementado en razón de 12 ha/año. En cuanto al NDVI, se ha detectado un incremento de los valores promedio para el periodo evaluado, siendo 0,26 el umbral (promedio de valores mínimos). El análisis de los datos climáticos muestra que la precipitación, temperatura máxima y mínima se han incrementado en 32  mm/dec, 0,3  °C/dec y 0,6  °C/dec respectivamente, siendo significativos (α<0,05) la temperatura máxima y mínima. Por último, los análisis de correlación y regresión muestran que la relación área de humedal-precipitación, NDVI-precipitación y área de humedal-NDVI son significativas para α<0,01, en cambio, la relación área de humedal-temperatura y NDVI-temperatura fueron significativos para α<0,05.[EN] The high Andean wetlands are considered fragile ecosystems that provide ecosystem services for the maintenance of Andean biodiversity and economy. However, currently the global threat of climate change puts them at serious risk, which is why the objective of this study is to determine the spatial-temporal and climatic variation of the high Andean wetlands of Chalhuanca (Peru), during the period 1986-2016. Landsat scenes were obtained during dry season in the years 1986, 1991, 1996, 2001, 2006, 2011, 2016, and using remote sensing techniques the area and vegetation index (NDVI) of the wetlands were calculated. For precipitation, maximum and minimum temperature, an analysis of moving averages, linear trends and the Mann-Kendall non-parametric statistical test was carried out, and finally the interaction between the variables was evaluated by using correlation and regression. The results show that the wetland area has increased by 12 ha/year. As for the NDVI, an increase of the average values for the evaluated period has been detected, being 0.26 the average of minimum values. Analysis of climate data shows that precipitation, maximum and minimum temperature have increased by 32 mm/dec, 0.3 °C/dec and 0.6 °C/dec respectively, with the maximum and minimum temperature being significant (α<0.05). Finally, correlation and regression analyses show that the wetland area-precipitation, NDVI-precipitation and wetland-NDVI relationships are significant for α<0.01, while the wetland-temperature and NDVI-temperature relationships were significant for α<0.05.Esta investigación fue financiada por la Universidad Nacional de San Agustín de Arequipa (UNSA) por contrato N° 047-2016-UNSA dentro del proyecto: “Servicios ecosistémicos de los humedales altoandinos y su contribución en la mitigación de los efectos del cambio climático: estudio de caso”, según contrato de subvención, también, se agradece al Tambo Chalhuanca (Programa Nacional PAIS – Midis), a los pobladores de la localidad de Chalhuanca y a la jefatura de la Reserva Nacional de Salinas y Aguada Blanca (Res. Jef. RNSyAB 002-2018-SERNANP-DGANP-JEF).Pauca-Tanco, A.; Ramos-Mamani, C.; Luque-Fernández, CR.; Talavera-Delgado, C.; Villasante-Benavides, JF.; Quispe-Turpo, JP.; Villegas-Paredes, L. (2020). Análisis espacio temporal y climático del humedal altoandino de Chalhuanca (Perú) durante el periodo 1986-2016. Revista de Teledetección. 0(55):105-118. https://doi.org/10.4995/raet.2020.13325OJS105118055Aguilar, H., Mora, R., Vargas, C. 2014. Metodología para la corrección atmosférica de imágenes Aster, Rapideye, Spot 2 y Landsat 8 con el módulo Flaash del software ENVI. Revista Geográfica de América Central, 53, 39-59. https://doi.org/10.15359/rgac.2-53.2Anderson, E., Marengo, J., Villalba, R., Halloy, S., Young, B., Cordero, D., Gast, F., Jaimes, E., Ruiz, D. 2011. Consecuencias del cambio climático en los ecosistemas y servicios ecosistémicos de los Andes tropicales. En Herzog, S., Martínez, R., Jorgensen, P. y Tiessen, H. 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Recuperado en septiembre de 2019, disponible en: http://www.aet.org.es/ revistas/revista38/Numero38_09.pdfGarcía, E., Otto, M. 2015. Caracterización ecohidrológica de humedales alto andinos usando imágenes de satélite multitemporales en la cabecera de Cuenca del Río Santa, Ancash, Perú. Ecología Aplicada, 14(2), 115-125. https://doi.org/10.21704/rea.v14i1-2.88Guerra, V., Ochoa, S. 2006. Evaluación espacio-temporal de la vegetación y uso del suelo en la Reserva de la Biosfera Pantanos de Centla, Tabasco (1990-2000). Investigaciones Geográficas, 59, 7-25.Haylock, M., Peterson, T., Alves, L., Ambrizzi, T., Anunciacao, M., Baez J., ... Vincent, L. 2006. Trends in total and extreme South American rainfall in 1960-2000 and links with sea surface temperature. Journal of Climate, 19, 1490-1512. https://doi.org/10.1175/JCLI3695.1IBM Corp. Released 2015. IBM SPSS Statistics for Windows, v23.0. Armonk, NY: IBM Corp.Jara, C., Delegido, J., Ayala, J., Lozano, P., Armas, A., Flores, V. 2019. Estudio de bofedales en los Andes ecuatorianos a través de la comparación de imágenes Landsat-8 y Sentinel-2. Revista de teledetección, 53, 45-57. https://doi.org/10.4995/raet.2019.11715Jaramillo, U., Cortés, J., Flórez, C. 2015. Colombia Anfibia. Un país de humedales. Bogotá: Instituto de Investigación de Recursos Biológicos Alexander von Humbolt.Kendall, M.G. 1975. Kendall Rank Correlation Methods. London: Griffin.Larsen, T., Brehm, G., Navarrete, H., Franco, P., Gómez, H., Mena, J., Morales, V., Argollo, J., Blacutt, L., Canhos, V. 2011. Desplazamientos de los rangos de distribución y extinciones impulsados por el cambio climático en los Andes tropicales: síntesis y orientaciones. En Herzog, S., Martínez, R., Jorgensen, P. y Tiessen, H. (Eds.), Cambio climático y biodiversidad en los Andes tropicales (pp. 57-82). Inter-American Institute for Global Change Research (IAI) and Scientific Committee on Problems of the Environment (SCOPE).Mann, H.B. 1945. Non parametric test against trend. Econometrica, 13, 245-259. https://doi.org/10.2307/1907187Maldonado-Fonkén, M. 2014. An introduction to the bofedales of the peruvian high Andes. Mires and Peat, 15(4), 1-13.Marengo, J., Pabón, J., Díaz, A., Rosas, G., Avalos, G., Montealegre, E., Villacís M., Solman S. M., Rojas, M. 2011. Cambio climático: evidencias y futuros escenarios en la región andina. En Herzog, S., Martínez, R., Jorgensen, P. y Tiessen, H. (Eds.), Cambio climático y biodiversidad en los Andes tropicales (pp. 131-150). Inter-American Institute for Global Change Research (IAI) and Scientific Committee on Problems of the Environment (SCOPE).Martínez, A., Rodríguez, J., Cabrera, A. 2014. Los paisajes de humedales, marco conceptual y aspectos metodológicos para su estudio y ordenamiento. Mercator (Fortaleza), 13(2), 169- 161. https://doi.org/10.4215/RM2014.1302.0012Mazzarino, M., Finn, J. T. 2015. An NDVI analysis of vegetation trends in an Andean watershed. Wetlands Ecology and Management, 24, 623-640. https://doi.org/10.1007/s11273-016-9492-0Medina, G., Mejía, A. 2014. Análisis multitemporal y multifractal de la desglaciación de la cordillera Parón en los Andes de Perú. Ecología Aplicada, 13(1), 35-42. https://doi.org/10.21704/rea.v13i1-2.452Mitsch, W., Gosselink, J. 2015. Wetlands. New Jersey: John Wiley y Sons, Inc.Mwita, E., Menz, G., Misana, S., Becker, M., Kisanga, D., Boehme, B. 2013. Mapping small wetlands of Kenya and Tanzania using remote sensing techniques. International Journal of Applied Earth Observation and Geoinformation, 21, 173-183. https://doi.org/10.1016/j.jag.2012.08.010Oñate-Valdivieso, F., Bosque, J. 2011. Estudio de tendencias climáticas y generación de escenarios regionales de cambio climático en una cuenca hidrográfica binacional en América del Sur. Estudios Geográficos, 270(27), 147-172. https://doi.org/10.3989/estgeogr.201107Otto, M., Schreder, D., Richters, J. 2011. Hydrology differentiation and spatial distribution of high altitude wetlands in a semi-arid Andean region derived from satellite data. Hydrology Earth System Science, 15, 1713-1727. https://doi.org/10.5194/hess-15-1713-2011Ozesmi, S.L., Bauer, M.E. 2002. Satellite remote sensing of wetlands. Wetland Ecology and Management, 10(5), 381-402. https://doi.org/10.1023/A:1020908432489Parra, A. Hernández, T., Francisco, L. 2010. Identificación y delimitación de humedales lénticos en el valle alto del río cauca mediante el procesamiento digital de imágenes de satélite. Ingeniería de Recursos Naturales y del Ambiente, 9, 78-88.Pekel, J.F., Cottam, A., Gorelick, N., Belward, A.S. 2016. High-resolution mapping of global surface water and its long-term changes. Nature, 540, 418- 422. https://doi.org/10.1038/nature20584Pérez, M., Llorca, J., Sanz, J. 2007. Evolución de la temperatura superficial desde el siglo XVIII. Nimbus, 19-20, 233-272.Polk, M., Young, K., Baraer, M., Mark, B., McKenzie, J., Bury, J., Carey, M. 2017. Exploring hydrologic connections between tropical mountain wetlands and glacier recession in Peru's Cordillera Blanca. Applied Geography, 78, 94-103. https://doi.org/10.1016/j.apgeog.2016.11.004Ponce, B. 2010. Detección y análisis del cambio de uso del suelo en la zona centro - norte de la provincia de Capitán Prat, XI Región período 1984-2003 (Tesis de grado). Universidad Austral de Chile, Valdivia.Rabatel, A., Francou, B., Soruco, A., Gomez, J., Cáceres, B., Ceballos, J., … Wagnon, P. 2013. Current state of glaciers in the tropical Andes: a multi-century perspective on glacier evolution and climate change. Cryosphere, 7, 81-102. https://doi.org/10.5194/tc-7-81-2013Robinson, A. B., Robinson, N. E., Soon, W. 2007. Environmental Effects of Increased Atmospheric Carbon Dioxide. Journal of American Physicians and Surgeons, 12, 79-90.Salvador, F., Monerris, J., Rochefort, L. 2014. Peatlands of the Peruvian Puna ecoregion: types, characteristics and disturbance. Mires and Peat, 15(3), 1-17.Salvador, M. 2017. Climap-aplicativo para análise de dados climáticos-versão 3.0. Revista Brasileira de Climatologia, 13(20), 349-374. https://doi.org/10.5380/abclima.v20i0.46351Skansi, M.M., Brunet, J., Sigró, E., Aguilar, J., Groening, O., Bentancur, Y., … Jones, P. 2013. Warming and wetting signals emerging from analysis of changes in climate extreme indices over South America. Global and Planetary Change, 100, 295-307. https://doi.org/10.1016/j.gloplacha.2012.11.004Solman, S., Nunez, M., Cabre, M.F. 2008. Regional climate change experiments over southern South America. I: Present Climate. Climate Dynamics, 30, 533-552. https://doi.org/10.1007/s00382-007-0304-3Seehaus, T., Malz, P., Sommer, C., Lipp, S., Cochachin, A., Braun, M. 2019. Changes of the tropical glaciers throughout Peru between 2000 and 2016 - mass balance and area fluctuations. 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Un nuevo grupo de manos paleolíticas pintadas en el sur de la Península Ibérica. La cueva de las Estrellas (Castellar de la Frontera, Cádiz)

Presentamos en este trabajo la revisión de las manifestaciones de arte rupestre conservadas en una estación localizada en la comunidad autónoma de Andalucía, conocida en la literatura precedente como cueva de Las Estrellas (Castellar de la Frontera, Cádiz). Se trata de un abrigo rocoso de grandes dimensiones, abierto al aire libre, en el que ya se había constatado, en los primeros años del presente siglo, la presencia de diversas pictografías de estilo esquemático. Durante una visita reciente al enclave se ha advertido, además, la existencia de un importante conjunto figurativo de cronología paleolítica que incluye representaciones de fauna y una pequeña serie de improntas de manos en negativo. Este artículo aborda el análisis genérico de las grafías catalogadas hasta el momento en la cavidad, atendiendo con especial detalle al conjunto de las citadas huellas de manos paleolíticas, que han sido documentadas usando tecnología digital 3d. De igual modo, se tendrán en cuenta su contextualización en el arte paleolítico andaluz y una primera aproximación cronológica a este interesante y variado complejo figurativo

Patient Selection in One Anastomosis/Mini Gastric Bypass—an Expert Modified Delphi Consensus

Purpose: One anastomosis/mini gastric bypass (OAGB/MGB) is up to date the third most performed obesity and metabolic procedure worldwide, which recently has been endorsed by ASMBS. The main criticisms are the risk of bile reflux, esophageal cancer, and malnutrition. Although IFSO has recognized this procedure, guidance is needed regarding selection criteria. To give clinicians a daily support in performing the right patient selection in OAGB/MGB, the aim of this paper is to generate clinical guidelines based on an expert modified Delphi consensus. Methods: A committee of 57 recognized bariatric surgeons from 24 countries created 69 statements. Modified Delphi consensus voting was performed in two rounds. An agreement/disagreement among ≥ 70.0% of the experts was considered to indicate a consensus. Results: Consensus was achieved for 56 statements. Remarkably, ≥ 90.0% of the experts felt that OAGB/MGB is an acceptable and suitable option "in patients with Body mass index (BMI) > 70, BMI > 60, BMI > 50 kg/m2 as a one-stage procedure," "as the second stage of a two-stage bariatric surgery after Sleeve Gastrectomy for BMI > 50 kg/m2 (instead of BPD/DS)," and "in patients with weight regain after restrictive procedures. No consensus was reached on the statement that OAGB/MGB is a suitable option in case of resistant Helicobacter pylori. This is likely as there is a concern that this procedure is associated with reflux and its related long-term complications including risk of cancer in the esophagus or stomach. Also no consensus reached on OAGB/MGB as conversional surgery in patients with GERD after restrictive procedures. Consensus for disagreement was predominantly achieved "in case of intestinal metaplasia of the stomach" (74.55%), "in patients with severe Gastro Esophageal Reflux Disease (GERD)(C,D)" (75.44%), "in patients with Barrett's metaplasia" (89.29%), and "in documented insulinoma" (89.47%). Conclusion: Patient selection in OAGB/MGB is still a point of discussion among experts. There was consensus that OAGB/MGB is a suitable option in elderly patients, patients with low BMI (30-35 kg/m2) with associated metabolic problems, and patients with BMIs more than 50 kg/m2 as one-stage procedure. OAGB/MGB can also be a safe procedure in vegetarian and vegan patients. Although OAGB/MGB can be a suitable procedure in patients with large hiatal hernia with concurrent hiatal hernia, it should not be offered to patients with grade C or D esophagitis or Barrett's metaplasia.info:eu-repo/semantics/publishedVersio