475 research outputs found

    Extended Apriori for association rule mining: Diminution based utility weightage measuring approach

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    The field of Association rule mining is a dynamic area for innovation of knowledge through which uncountable procedures have been expounded. Recently, by including significant components viz. value (utility), volume of items (weight) etc, the researchers have enhanced the quality of association rule mining for industry by bringing out the association designs. In this note, a proficient methodology has been put forward based on weight factor and utility for effective digging out of important association rules. At the very beginning, a traditional Apriori algorithm has been utilized that make use of the anti-monotone property which states that if n items are recurring continuously then n-1 items should also recur by which the scores of weightage(W-Gain), utility(U-Gain) and diminution(D-sum), are derived at. Eventually, we derive a subset of important association rules through which EUW-Score is generated. The tentative outcome demonstrates the effectiveness of the methodology in generating high utility association rules that is profitably used for the business improvement

    Engaging scientists through institutional histories

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    An institutional history is a narrative that records key points about how institutional arrangements – new ways of working – evolve over time creating more effective ways to achieve goals. It can be used to document institutional innovations in projects and to highlight barriers to change. An institutional history draws out and synthesizes lessons for research organizations and partners as well as for others in similar circumstances

    Urea and ascorbic acid as ameliorators of cement dust toxicity in Oryza Sativa Var. B.P.T.5204

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    The present study is an attempt to find out the amelioration of urea and ascorbic acid on the inhibitory effect of cement dust on Oryza Sativa (Var. B.P.T.5204). The observations have shown that rice was quite sensitive to cement dust when applied at 3g/m2 daily from three leaf stage until harvest of the crop. The response was analysed in terms of number of leaves, total height, biomass and panicle characters. Urea and ascorbic acid were observed to be quite potent in reverting the inhibitory effect of cement dust. Urea could bring the maximum recovery in shoot and root biomass. These two substances were very useful in reverting the effect of cement dust in terms of height of the plant. Urea increased seed weight upto 35% while ascorbic acid upto 13.4%

    Cytokinin Interplay with Ethylene, Auxin, and Glucose Signaling Controls Arabidopsis Seedling Root Directional Growth

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    Optimal root architecture is established by multiple intrinsic (e.g. hormones) and extrinsic (e.g. gravity and touch) signals and is established, in part, by directed root growth. We show that asymmetrical exposure of cytokinin (CK) at the root tip in Arabidopsis (Arabidopsis thaliana) promotes cell elongation that is potentiated by glucose in a hexokinase-influenced, G protein-independent manner. This mode of CK signaling requires the CK receptor, ARABIDOPSIS HISTIDINE KINASE4 and, at a minimum, its cognate type B ARABIDOPSIS RESPONSE REGULATORS ARR1, ARR10, and ARR11 for full responsiveness, while type A response regulators act redundantly to attenuate this CK response. Ethylene signaling through the ethylene receptor ETHYLENE RESISTANT1 and its downstream signaling element ETHYLENE INSENSITIVE2 are required for CK-induced root cell elongation. Negative and positive feedback loops are reinforced by CK regulation of the expression of the genes encoding these elements in both the CK and ethylene signaling pathways. Auxin transport facilitated by PIN-FORMED2 as well as auxin signaling through control of the steady-state level of transcriptional repressors INDOLE-3-ACETIC ACID7 (IAA7), IAA14, and IAA17 via TRANSPORT INHIBITOR RESPONSE1/AUXIN SIGNALING F-BOX PROTEIN are involved in CK-induced root cell elongation. This action lies downstream of ethylene and CK induction. Intrinsic signaling in this response operates independently of the extrinsic signal touch, although actin filament organization, which is important in the touch response, may be important for this response, since latrunculin B can induce similar growth. This root growth response may have adaptive significance, since CK responsiveness is inversely related to root coiling and waving, two root behaviors known to be important for fitness

    Hypocotyl Directional Growth in Arabidopsis: A Complex Trait

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    The growth direction of the Arabidopsis (Arabidopsis thaliana) etiolated-seedling hypocotyl is a complex trait that is controlled by extrinsic signals such as gravity and touch as well as intrinsic signals such as hormones (brassinosteroid [BR], auxin, cytokinin, ethylene) and nutrient status (glucose [Glc], sucrose). We used a genetic approach to identify the signaling elements and their relationship underlying hypocotyl growth direction. BR randomizes etiolated-seedling growth by inhibiting negative gravitropism of the hypocotyls via modulating auxin homeostasis for which we designate as reset, not to be confused with the gravity set point angle. Cytokinin signaling antagonizes this BR reset of gravity sensing and/or tropism by affecting ethylene biosynthesis/signaling. Glc also antagonizes BR reset but acts independently of cytokinin and ethylene signaling pathways via inhibiting BR-regulated gene expression quantitatively and spatially, by altering protein degradation, and by antagonizing BR-induced changes in microtubule organization and cell patterning associated with hypocotyl agravitropism. This BR reset is reduced in the presence of the microtubule organization inhibitor oryzalin, suggesting a central role for cytoskeleton reorganization. A unifying and hierarchical model of Glc and hormone signaling interplay is proposed. The biological significance of BR-mediated changes in hypocotyl graviresponse lies in the fact that BR signaling sensitizes the dark-grown seedling hypocotyl to the presence of obstacles, overriding gravitropism, to enable efficient circumnavigation through soil

    Maternal vitamin D deficiency associated with neonatal hypocalcaemic convulsions

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    Maternal vitamin D insufficiency is not uncommon. Infants born to mothers who are deficient in vitamin D and or calcium, usually due to cultural modifications in their diets or clothing habits, and in addition are breastfed, are at risk of developing vitamin D deficiency and hypocalcaemia. We present a case of neonatal hypocalcaemic seizures secondary to vitamin D deficiency
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