Norleucine, a natural occurrence in a novel ergot alkaloid γ-ergokryptinine

A novel natural peptide ergot alkaloid γ-ergokryptinine containing norleucine has been isolated from ergot sclerotia of the field-growing parasitic fungus Claviceps purpurea CCM 8059. Its structure was deduced from the NMR and mass spectral data. The final structural proof was provided by the crystal structure determination, which is the first X-ray structure of a natural Nle-containing secondary metabolite. The conformations of three ergopeptinines: γ-ergokryptinine, ergoladinine, and α-ergokryptinine were compared. © Springer-Verlag 2005

Cyclické peptidy a depsipeptidy jako markery houbových infekcí

Fungi produce cyclic peptides and depsipeptides by multifunctional synthetases

Application of the conservative averaging for the filtration problem with large velocity

In this paper we consider a filtration problem in a rectangle or a perturbed rectangle region with an essential nonlinearity and high values of velocity. The conservative averaging method with quadratic or rational approximation over the rectangle thickness gives us 1D problem instead of the original 2D problem. This ID solution can be used as an initial approximation for the original 2D problem. The conservative averaging method is considered and results of some numerical experiments are presented. Filtracijos uždavinio su dideliaias greičiais sprendimas konservatyviu vidurkinimo metodu Santrauka Straipsnyje sprendžiamas dvimatis filtracijos uždavinys. Sritis yra stačiakampe arba deformuota stačiakampe. Nagrinejamas atvejis, kai skysčio tekejimo greitis yra didelis ir būtina naudoti netiesini matematini modeli. Panaudojant vidurkinimo metoda y koordinates kryptimi sprendinys aproksimuojamas parabole, o lygtis yra vidurkinama. Gautoji vienmate difuzijos‐konvekcijos lygtis yra sprendžiama skaitiškai. Taip sudarytas sprendinys ne visada yra monotoniškas, todel nagrinejamas ir dar vienas artinys, kuris aprašomas racionalia trupmena. Pateikti skaičiavimo eksperimento rezultatai, gauti sprendžiant uždavini dviem atvejais, kai vyrauja konvekcijos procesas arba difuzijos procesas. Algoritmo ir iteracinio proceso konvergavimas nera ištirtas. First Published online: 14 Oct 201

Detection of lipophorin as the major cyclosporin-binding protein in the hemolymph of the greater wax moth Galleria mellonella

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