168 research outputs found
Vortices on demand in multicomponent Bose-Einstein condensates
We present a simple mechanism to produce vortices at any desired spatial
locations in harmonically trapped Bose-Einstein condensates (BEC) with
multicomponent spin states coupled to external transverse and axial magnetic
fields. The vortices appear at the spatial points where the spin-transverse
field interaction vanishes and, depending on the multipolar magnetic field
order, the vortices can acquire different predictable topological charges. We
explicitly demonstrate our findings, both numerically and analytically, by
analyzing a 2D BEC via the Gross-Pitaevskii equation for atomic systems with
either two or three internal states. We further show that, by an spontaneous
symmetry breaking mechanism, vortices can appear in any spin component, unless
symmetry is externally broken at the outset by an axial field. We suggest that
this scenario may be tested using an ultracold gas of Rb occupying all
three states in an optical trap.Comment: 11 pages, 9 figures, (Accepted in PRA
Evolution of the microstructure, texture and creep properties of the 7075 aluminium alloy during hot accumulative roll bonding
The 7075 Al alloy was severely deformed at 350 °C by a 3:1 thickness reduction per pass accumulative roll bonding (ARB) process up to six passes. It was found that discontinuous recrystallisation occurs during the inter-pass annealing stages from the third pass on, attributable to the increment of the mean particle size during processing. As a consequence, the mean crystallite size did not decrease, but remained approximately constant at 440 nm along the present ARB process and the mean boundary misorientation angle reached a maximum of 30° for the 3-passes sample. However, since nucleation of new grains takes place at the pre-existing grain boundaries, discontinuous recrystallisation results in slight changes in texture throughout the processing, being the orientations in the ARBed samples predominantly located along the typical rolling β-fibre. Uniaxial tests conducted at 300 °C and 350 °C revealed that the operating deformation mechanism in the processed alloy at such temperatures was grain boundary sliding; the optimum superplastic strain rate being 3×10−3–10−2 s−1. Boundary misorientation and thermal stability are the two main factors that contribute to high elongations to failureFinancial support from the CICYT (Projects MAT2009-14452 and MAT2012-38962)Peer reviewe
Gene Expression Integration into Pathway Modules Reveals a Pan-Cancer Metabolic Landscape
BIO2014-57291-R and SAF2017-88908-R from the Spanish Ministry of Economy and Competitivenessgrant PI15/00854 from the FIS“Plataforma de Recursos Biomoleculares y Bioinformáticos” PT17/0009/0006 from the ISCIII, cofunded with European Regional Development FundsFP7-PEOPLE-2012-ITN MLPM2012EU H2020-INFRADEV-1-2015-1 ELIXIR-EXCELERAT
Models of cell signaling uncover molecular mechanisms of high-risk neuroblastoma and predict disease outcome
Spanish Ministry of Economy and Competitiveness grant BIO2014–57291-RSpanish Ministry of Economy and Competitiveness grant SAF2017–88908-R“Plataforma de Recursos Biomoleculares y Bioinformáticos” PT13/0001/0007EU H2020-INFRADEV-1-2015-1 ELIXIR-EXCELERATE (ref. 676559)EU FP7-People ITN Marie Curie Project (ref 316861)
Hydrogenation of α,β-Unsaturated Carbonyl Compounds over Covalently Heterogenized Ru(II) Diphosphine Complexes on AlPO4-Sepiolite Supports
In this work, the covalent immobilization of two ruthenium(II) complexes, i.e., [RuIICl (bpea){(S)(-)(BINAP)}](BF4), 1, and [RuIICl(bpea)(DPPE)](BF4), 2, where BINAP = 2,2’-bis(diphenylphosphino)-1,1’-binaphthyl and DPPE = 1,2-bis(diphenylphosphino)ethane, have been obtained (AlPO4-Sepiolite@1 and AlPO4-Sepiolite@2) by using a N-tridentate ligand N,N-bis-(2-pyridylmethyl)ethylamine (bpea), linked to an amorphous AlPO4-Sepiolite (20/80) inorganic support. This AlPO4-sepiolite support is able to immobilize the double amount of ruthenium complex (1.65%) than the amorphous AlPO4 (0.89%). Both heterogenized complexes have been assessed as catalysts in the liquid phase hydrogenation of several substrates with carbonyl and/or olefinic double bonds using methanol as solvent, attaining good catalytic activity and high enantioselectivity (99%). The highest Turn Over Number (TON) value (748.6) was obtained over the [RuII Cl (bpea)(DPPE)](BF4) 2 catalyst, although the [RuIICl(bpea){(S)(-)(BINAP)}](BF4) 1 exhibits better reusability. In fact, the [RuIICl(bpea){(S)(-)(BINAP)}](BF4) immobilized on AlPO4-Sepiolite maintained the activity throughout 14 successive runs. Furthermore, some findings on hydrogenation mechanisms of the α,β-unsaturated carbonyl compounds over Ru catalysts have been also obtained
High throughput estimation of functional cell activities reveals disease mechanisms and predicts relevant clinical outcomes
This work is supported by grants BIO2014- 57291-R from the Spanish Ministry of Economy and Competitiveness and “Plataforma de Recursos Biomoleculares y Bioinformáticos” PT13/0001/0007 from the ISCIII, both co-funded with European Regional Development Funds (ERDF); PROMETEOII/2014/025 from the Generalitat Valenciana (GVA-FEDER); Fundació la Marató TV3 (ref. 20133134); and EU H2020- INFRADEV-1-2015-1 ELIXIR-EXCELERATE (ref. 676559) and EU FP7-People ITN Marie Curie Project (ref 316861)
CARMENES input catalogue of M dwarfs IV. New rotation periods from photometric time series
Aims. The main goal of this work is to measure rotation periods of the M-type
dwarf stars being observed by the CARMENES exoplanet survey to help distinguish
radial-velocity signals produced by magnetic activity from those produced by
exoplanets. Rotation periods are also fundamental for a detailed study of the
relation between activity and rotation in late-type stars. Methods. We look for
significant periodic signals in 622 photometric time series of 337 bright,
nearby M dwarfs obtained by long-time baseline, automated surveys (MEarth,
ASAS, SuperWASP, NSVS, Catalina, ASAS-SN, K2, and HATNet) and for 20 stars
which we obtained with four 0.2-0.8 m telescopes at high geographical
latitudes. Results. We present 142 rotation periods (73 new) from 0.12 d to 133
d and ten long-term activity cycles (six new) from 3.0 a to 11.5 a. We compare
our determinations with those in the existing literature; we investigate the
distribution of P rot in the CARMENES input catalogue,the amplitude of
photometric variability, and their relation to vsin i and pEW(Halfa); and we
identify three very active stars with new rotation periods between 0.34 d and
23.6 d.Comment: 34 pages, 43 figures, 2 appendix table
Holistic view of biological nitrogen fixation and phosphorus mobilization in Azotobacter chroococcum NCIMB 8003
Nitrogen (N) and phosphorus (P) deficiencies are two of the most agronomic
problems that cause significant decrease in crop yield and quality. N and P chemical
fertilizers are widely used in current agriculture, causing environmental problems and
increasing production costs. Therefore, the development of alternative strategies to
reduce the use of chemical fertilizers while maintaining N and P inputs are being
investigated. Although dinitrogen is an abundant gas in the atmosphere, it requires
biological nitrogen fixation (BNF) to be transformed into ammonium, a nitrogen
source assimilable by living organisms. This process is bioenergetically expensive
and, therefore, highly regulated. Factors like availability of other essential elements,
as phosphorus, strongly influence BNF. However, the molecular mechanisms of
these interactions are unclear. In this work, a physiological characterization of BNF
and phosphorus mobilization (PM) from an insoluble form (Ca3(PO4)2) in Azotobacter
chroococcum NCIMB 8003 was carried out. These processes were analyzed
by quantitative proteomics in order to detect their molecular requirements and
interactions. BNF led to a metabolic change beyond the proteins strictly necessary
to carry out the process, including the metabolism related to other elements, like
phosphorus. Also, changes in cell mobility, heme group synthesis and oxidative stress
responses were observed. This study also revealed two phosphatases that seem
to have the main role in PM, an exopolyphosphatase and a non-specific alkaline
phosphatase PhoX. When both BNF and PM processes take place simultaneously, the
synthesis of nitrogenous bases and L-methionine were also affected. Thus, although
the interdependence is still unknown, possible biotechnological applications of these
processes should take into account the indicated factors.Datos de investigación disponibles en: https://www.frontiersin.org/articles/10.3389/fmicb.2023.1129721/full#supplementary-materia
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