Design and Implementation of Scientific Research Files Management System Based on ASP.NET

科研档案管理是高等院校和科研机构管理系统中最主要的组成部分，建立一个功能齐全的科研档案管理系统不仅可以为单位领导的计划提供参考，还可以提高科研档案管理的效率。随着互联网与通信技术的不断融合发展，企业内部网络互联互通和构建完成，因此，建立一个具有可维护性、可重用性、可扩充性和安全可靠性，并适应需求变化的网络科研档案管理系统是科研机构迫切需要的。 本文在.Net环境下对软件开发的分层设计思想进行了介绍，并借助SQLServer2005、C#语言、AJAX技术构建了一个界面友好、层次清晰的科研档案管理系统。在此系统的开发过程中，本人主要负责用户个人信息管理、用户角色管理、数据库转换、成果鉴定和专家...Research Archives Management in institutions of higher learning and research institutions management system, the most important part of establishing a fully functional research archives management system can not only provide a reference for unit leaders plan also largely improve the efficiency of research and archives management. With the convergence of Internet and communications technology, inte...学位：工程硕士院系专业：软件学院_工程硕士(软件工程)学号：X201323190

自动复位通配型安全手术刀柄的设计

目的克服普通手术刀柄所装载的刀片裸露易误刺、术中必须采取被动防护措施等缺欠,并提高依从性、适配性及经济性。方法参照并遵从国标,借鉴课题组昔研的滑移护刃鞘、卡簧定位钮及闭式自动复位等相关专利设计了安全便捷的\"内藏式自动复位捷卸式通配型并置刀架\",益于直接安全传递。结果通过外科医生及手术室护士实际装卸刀片并进行问卷调查统计,结果显示自动刀柄装卸用时更短(P<0.05),医护的使用满意率更高(P<0.05)。结论自动刀柄保险御刺、舒握抗损、简骤增效、降耗环保、以一代多、人机和谐、便携易储。福建省医学创新课题(2017-CXB-21

Application of Fuzzy Control in Intelligent Traffic Lights Monitoring System

为了解决拥挤的城市交通问题,针对交通灯监控系统中可变的交通状况,提出一种基于模糊算法的监控系统。应用模糊算法,通过模糊控制实现交通灯的控制,使道路通畅。对监控系统进行分析,合理选择模糊控制器的结构,根据动态的车流量,通过模糊算法分配当前车道的通行时间,并全面考虑同时通行的各种车道组合。该监控系统提高了车辆通行效率,使道路更为通畅。与传统的固定配时系统相比,它更适于当前纷繁复杂的交通状况。In order to solve the crowded transportation problem of cities,in view of the variable traffic condition in the traffic lights monitoring system,proposed to use the fuzzy algorithm and the fuzzy control to realize the control of the traffic lights.Making the analysis to the monitoring system,selected the fuzzy controller structure in reason.It assigned the pass time of each traffic lane through the fuzzy algorithm according to the dynamic volume of vehicle.In the paper it has considered all kinds of traffic lanes combination pass through in the same time.The monitoring system enhanced the efficiency of vehicles traffic,caused the path to be more unobstructed.Compared with the traditional fixed timing systems,it is more suitable to the complexity of current traffic conditions

Algorithm design and application research of Josephus problem

Josephus问题是组合数学的发展源头之一。关于Josephus问题的描述形式甚多。文章通过实验和分析,总结了一个通用性的描述形式,并给出了基于循环链表的算法设计。算法的数据源从文本文件中获取,增强了算法的实用性;根据数据元素值的递增顺序建立循环链表,能够有效地分类数据,使Josephus数据序列均匀分布且不重复。文章还给出了Josephus问题的若干个应用实例,包括将Josephus问题应用于通用试题库的组卷算法和找出一组数据中某个指定范围的数据序列等。Josephus problem is one of the headstreams of combinatorics.There are so many methods to descript the Josephus problem now.In this paper,after so many experiments and analysis,a common method is summarized and an algorithm is designed,which is based on circular linked list.The data source of the algorithm is from text file,so the practicability is enhanced.And since the circular linked list is created based on the ascendant sequence of the data list,so the data can be classified effectively to make the Josephus data list to be distributed symmetrically and no duplicate.Some applications of Josephus problem is offered,which include the test paper combination algorithm in common test questions database,and finding a list of data,which belongs to certain range,from a set of data,etc.福建省科技重大专项(2004HZ02);; 厦门大学科学研究基金资助项目(Y07002)

Graduate Students Participate in Physical Chemistry Experiment Teaching Process

物理化学实验是一门理论性、实践性和技术性较强的基础化学实验课程之一。研究生助教参与实验教学是高校教学改革的一个重要组成部分。本文就我校近几年研究生助教参与物理化学实验教学浅谈一点感想。Physical chemistry experiment is one of basic course of chemical experiment with theoretical,practical and highly technical qualities.Graduate students participate in experiment teaching process is an important part of teaching reform in colleges and universities.In this paper,some reflections were given on graduate students participate in physical chemistry experiment teaching process in our university in recent years.国家基础科学人才培养基金J1210014项目资

Studying Thermodynamics of the Saponification of Ethyl Acetate

介绍基于量热法的热动力学原理。利用该方法测定了乙酸乙酯皂化反应的速率常数,并比较了该方法与电导法的优缺点。Micro-calorimetric method for studying thermodynamics of the saponification of ethyl acetate has been introduced.The reaction rate constant can be calculated easily from the related dates measured.Studies have also been carried out to compare the micro-calorimetric method with the electrical conductivity detection.国家基础科学人才培养基金(No.J1210014

Introducing New Ideas in the Traditional Experiment Teaching

以一个经典的基础物理化学实验——“酸催化蔗糖水解反应“为例,浅谈如何通过丰富实验内容,帮助学生辩证区分在传统实验方法中,近似处理的合理性及限制条件;设计新实验方法,提高实验的效率;引入新的广谱性实验技术,使学生进一步理解化学热力学和动力学之间的联系,拓展学习思路、强化实验技术、培养创新意识,开发并引导学生了解和利用新的实验技术更好地进行科学研究。在传统实验教学中突出“新意“,激发学生追求、尝试创新的兴趣与热情,鼓舞学生自己动手设计、改进实验,引入“新“内容,从而培养其创新意识与能力。Taking a classic physical chemistry experiment "the hydrolysis of sucrose catalyzed by acid "as an example,the paper discusses how to enrich experiment contents,help students dialectical distinguish in traditional experiment method,the rationality of the approximate treatment and constraints.It designs a new experimental method to improve the efficiency of the experiment; By introducing a new broad spectrum experiment technology,the students are more interesting in experiment and can further understand the relationship between chemical thermodynamics and kinetics,expand the study thinking,strengthen experiment technology,cultivate creative consciousness,develop and guide students to understand and take advantage of new experimental technology for scientific research better.Highlighting the"new" in the traditional experimental teaching can inspire students ' interest and enthusiasm to pursuit,and to innovation,encourage students to oneself start work design,improvement of the experiment,the introduction of "new"content also cultivate students' innovation consciousness and ability.国家基础科学人才培养基金项目资助(J1210014

MEMS Infrared Emitter Based on SOI Wafer

提出了一种利用微机电系统(MEMS)制造工艺技术制备的硅基微型红外光源。该光源使用绝缘体上硅(SOI)晶片作为基底材料,其上沉积多晶硅材料并通过离子注入工艺实现材料的电阻加热发光特性,SOI晶片上的单晶硅层通过重掺杂实现辐射光背向吸收自加热效应。利用SOI晶片中的掩埋二氧化硅层为刻蚀停止层,通过背面深反应离子刻蚀(drIE)技术制备微米量级的薄膜发光层结构。光源表面工作温度和辐射光谱分别通过红外热像仪和光谱辐射计测量得到。实验结果表明,该光源在表面温度约700 k时,1.3--14.5μM波长内的能量转换效率约为5.58%,光源的调制频率在50%的调制深度下接近40 Hz。A micro-electro-mechanical systems(MEMS) infrared(IR) emitter is presented.The IR emitters are fabricated on silicon-on-insulator(SOI) wafer,and the resistance heating film on the SOI wafer used boron-doped polysilicon by ion implantation technology.The single crystal silicon on SOI wafer is designed as a heavily-doped infrared absorption layer for realizing the self-heating effect.The light-emitting layer is fabricated by using deep reactive ion etching(DRIE)process on the backside of SOI wafer,and the buried SiO2 layer of the SOI wafer is used as etching stop layer to control the thickness of light-emitting layer.The surface temperature and emission spectrum of IR emitter are measured by thermal imaging system and spectroradiometer.The experimental results show that in the case of surface temperature of about 700 K,the energy conversion efficiency is about 5.58% in the spectrum range of 1.3--14.5 μm.The experiments also show that the modulation frequency can reach to 40 Hz at 50% modulation depth.航空科学基金(20080868011;20080868009)资助课

Apoptosis of Human Esophageal Carcinoma Cell Line EC9706 Induced by Curcumin

目的:应用姜黄素处理人食管癌EC9706细胞,研究姜黄素对人食管癌EC9706细胞凋亡的诱导作用。方法:应用细胞计数、流式细胞仪、琼脂糖凝胶电泳、Hoechst染色、H.E染色和透射电镜检测经姜黄素诱导处理后人食管癌EC9706细胞的凋亡。结果:经姜黄素诱导处理后,人食管癌EC9706细胞生长抑制率达69.9%;细胞周期检测出现亚二倍体(亚G1期)细胞峰值,细胞凋亡率达23%;琼脂糖凝胶电泳显示出细胞凋亡典型的180-200 bp及其倍体的DNA"梯状"条带;Hoechst染色显示细胞核内出现浓染致密的固缩形态或颗粒状荧光;光镜和电镜下可见典型的细胞凋亡特征:细胞体积缩小,染色体凝集,可见有成群或单独存在的凋亡细胞,电镜下可见凋亡小体存在。结论:姜黄素能够有效诱导人食管癌EC9706细胞的凋亡,从而进一步为食管癌等恶性肿瘤疾病的治疗和凋亡机理的研究提供重要基础和科学依据.Objective: To study the apoptosis effects of the human esophageal carcinoma cell line EC9706 cells induced by curcumin(Cur). Methods: The apoptosis effects of EC9706 cells induced by curcumin were detected by cell count, flow cytometry analysis, light microscope and electron microscope. Results: After treated with curcumin, the proliferation of EC9706 cells was inhibited, and the inhibitory rate was 69.9%. The results of flow cytometry analysis showed that curcumin could induce the emergence of the phase of apoptosis, and the rate was 23%. Agarose gel electrophoresis revealed that cell DNA fragment exhibited characteristic "DNA ladder".Cell nucleus concentrated and appeared granular fluorescence by Hoechst33258 staining. Light microscope and electron microscope showed that the morphology of the cells treated with curcumin appeared shrinked, cell nucleus concerntrated, chromatin agglutinated, mitochondria swelled, and apoptosis body formed. Conclusion: This study suggested that curcumin could induce apoptosis of the human esophageal carcinoma cell line EC9706 effectively, and provided important foundation and research proofs to study more about the therapy of esophageal carcinoma, the malignant tumor and apoptosis mechanisms.国家自然科学基金项目(30470877

Expression and Localization of Nucleophosmin During Curcumin-induced Apoptosis in the Immortalized Human Epithelial HaCaT Cells

该文以姜黄素诱导处理前后的人永生化表皮HACAT细胞为研究对象,对核仁磷酸蛋白(nuClEOPHOSMIn,nPM)在核基质中存在、分布及其与凋亡相关基因产物在姜黄素处理前后HACAT细胞中的共定位关系进行观察研究。WESTErn blOT结果显示,nPM存在于人永生化表皮HACAT细胞核基质蛋白组分中,并在姜黄素处理后的细胞核基质中表达下调,免疫荧光显微镜观察显示,nPM定位在核基质上,经姜黄素处理后出现分布位置与表达水平的变化,激光共聚焦显微镜观察可见nPM与HACAT细胞中凋亡相关基因bAX、bCl-2、MTP53和rb基因产物均存在共定位关系,但在姜黄素处理后细胞中其共定位分布区域出现变化。研究结果证实nPM是一种核基质蛋白,定位于核基质上,nPM在HACAT细胞诱导凋亡过程中的表达分布及其与凋亡相关基因产物的共定位现象值得进一步探索和研究。To explore the existence and distribution of nucleophosmin(NPM) in the nuclear matrix and its colocalization with the other apoptosis-related gene products following curcumin treatment in the human epithelial HaCaT cells,the nuclear matrix of HaCaT cells was extracted pre/post curcumin induced apoptosis.Western blot analysis showed that NPM existed in the fractions of nuclear matrix proteins and was down-regulated after curcumin treatment.The immunofluorescence observation revealed that NPM located in the nuclear matrix,curcumin treatment altered its expression level and distribution profile.The colocalization of NPM with the products of apoptosis-related repression genes,including Bax,Bcl-2,mtP53 and Rb,using laser scanning confocal microscopy,were evaluated,and substantial differences were observed following curcumin treatment.The results implied that NPM is a nuclear matrix protein,and the level of its expression and the colocalization with apoptosis-related gene products may play an important role during the apoptosis of HaCaT cells.国家自然科学基金(批准号:30871241)资助的课题~