真空調理とスチームコンベクションオーブン調理の検討[令和2年度中間報告]

令和2年度学術研究所助成研究中間報告・自由課題研

継続看護が必要な患者の在宅移行を円滑にする要因及び困難にする要因 訪問看護ステーションにおける退院時連携の実態調査から

継続看護が必要な患者の在宅移行を円滑にする要因、および困難にする要因を明らかにすることを目的に、宮崎県内の全訪問看護事業所を対象に、医療機関との退院時連携により在宅支援が円滑であった事例と困難であった事例を各1事例挙げてもらう自由記述を含むアンケート調査を行い、37施設より回答を得た(回収率35.2%)。自由記述の内容分析から、在宅移行を円滑に行うための要因として、記述数の多い順に、【退院前カンファレンスや関係者より、入院中および訪問開始までの状況について多くの事前情報を得たり、支援の方向性を共有すること】【病棟や医師、在宅医との話し合いを重ね、病状や起こりうるリスクの予測ができること】【訪問開始までに時間的な余裕があること】【在宅療養に必要な物品がスムーズに準備できること】の4つのカテゴリーが、また、在宅移行を困難にする要因として、記述数の多い順に、【在宅までの支援体制が不十分なまま退院】【医師からの家族や本人への病状説明が不十分なままの退院】【重篤な状態での、急な訪問看護の依頼】【介護力が乏しい】の4つのカテゴリーが、それぞれ抽出された

Analysis of the Vascular Configuration in 111 Hemifacial Spasm Patients ?Vascular common stem anomaly as a pathophysiological cause of hemifacial spasm?

One hundred and fifteen patients with hemifacial spasm were treated by micro vascular decompression surgery. 73 patients out of all patients were studied by the bilateral vertebral angiograms which were obtained by means of stereotactic straight antero?posterior roentgenograms with subtraction, and 38 patients were examined by unilateral vertebral angiograms of the affected side. 4 patients were not examined. According to detail study of these angiograms, of 111 patients, many variations of posterior inferior cerebellar artery ( PICA ) and anterior interior cerebellar artery ( AICA ) were found, The characteristic configuration of the vessels in posterior fossa of the hemifacial spasm patients were common stem anomaly ( common stem AICA and common stem PICA). The incidence of common stem artery which compressed the exit zone of facial nerve in right facial spasm patiens was 75.4 %, and 57.4 % in left facial spasm patients. The frequency of bilateraly common stem vessels which means high grade of anomaly was 45.0 % in right affected patients, and 27.3 % in left ill patients. In young female patients, the high incidence and high degree of common stem anomaly of the vessels was observed more frequently. These findings might suggest that the developmental anomaly of vessels in posterior fossa might be one of the factors of hemifacial spasm, and high frequency rate of hemifacial spasm in female

Preparation and Characterization of a Hybrid Complex of Cyclodextrin-Based Metal—Organic Frameworks-1 and Ascorbic Acid Derivatives

Cyclodextrin-based metal–organic frameworks-1 (CD-MOF-1) prepared using potassium hydroxide, ethanol, and γ-cyclodextrin (γ-CD) has been reported as a new type of MOF for the development of pharmaceutical formulations. The present study aimed to investigate the physicochemical properties of ascorbic acid derivatives (L-ascorbyl 6-palmitate (ASCP); L-ascorbyl 2,6-palmitate (ASCDP)) complexed with CD-MOF-1 by a solvent evaporation method. Powder X-ray diffraction revealed that the crystal diffraction pattern of CD-MOF-1 changed from α-type to β-type when prepared by a solvent evaporation method. For ASCP/CD-MOF-1 = 1/2 and ASCDP/CD-MOF-1 = 1/4 evaporated samples, the crystal diffraction peaks derived from ASCP and ASCDP disappeared, indicating a β-like behavior. Differential scanning calorimetry results revealed that the endothermic peaks of evaporated samples (ASCP/CD-MOF-1 = 1/2 and ASCDP/CD-MOF-1 = 1/4) were not detected due to melting. Furthermore, intermolecular interactions were observed in the hydrogen bonds between the CH groups of the side chains of ASCP and ASCDP and the OH group of CD-MOF-1 in (ASCP/CD-MOF-1 = 1/2) and EVP (ASCDP/CD-MOF-1 = 1/4), based on the near-infrared absorption spectroscopy analysis. CD-MOF-1 did not form inclusion complexes with the lactone rings of ASCP and ASCDP, but with the lipophilic side chains. These results suggested that CD-MOF-1 may be useful in preparing novel drug carriers for ASCP and ASCDP.Article No.7309 This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cite