Support for Elementary School Students' University Exploration by the Department of Chemistry and Life Sciences, Faculty of Science

地域教育実践報告 / Report

Community-based Experiential Learning in Seminar and its Outcomes : Exploring Ogawa Town’s Historical Sites as Active Learning of the Murakoshi Seminar

地域教育実践報告 / Report

Educational and Social Effects of Student Volunteering : A University-Based Mutual Aid Model for Community Regeneration

This study reconceptualizes university student volunteer activities not merely as educational programs or supplementary community support, but as a core social structure that reproduces local communities through mutual aid mechanisms. Based on comparative analysis of four community-based practices, the study empirically demonstrates the structural processes and ripple effects through which student participation simultaneously generates educational and social outcomes. The analysis reveals three interrelated structural mechanisms. First, university-community collaboration is not primarily established through formal institutional design, but through the accumulation of relational trust developed in continuous field-based engagement. Second, student participation functions not simply as supplementary labor, but as a catalyst that reorganizes local relational structures and facilitates the reproduction of mutual aid networks. Third, students’ educational development particularly the formation of self-efficacy and civic engagement and community transformation such as revitalization of social relationships and expansion of participatory structures are mutually reinforcing processes that constitute a cyclical mechanism. The findings indicate that educational and social effects are not produced in parallel, but are simultaneously generated within a single structural cycle. This study therefore redefines universities not only as educational institutions, but also as social infrastructures that enable continuous circulation of human relationships, learning, and community participation. Furthermore, the proposed mutual-aid-based community regeneration model presents a new structural principle for designing sustainable local societies in the context of population decline. It suggests repositioning universities as core hubs of regional human-resource circulation systems, and reconceptualizing students as cyclical community actors rather than temporary supporters. This model provides a foundational framework for sustainable community regeneration and has potential applicability at the national level.論文 / Article

Pharmaceutical Workshop on the Drug Safety for 6th Grade Elementary School Pupils Organized by 4th Grade Undergraduates Student in Experimental Communication Practice

地域活動ノート / Note

Journal of Josai Community Liaison Center No.6 JU 60th Anniversary Issue

編集：城西大学・城西短期大学地域連携センター紀要編集委員

How Does Social Capital Contribute to Cultural Heritage Transmission? : A Preliminary Survey for the Development of a Regional Plan for the Preservation and Utilization of CulturalProperties in Higashichichibu Village

地域調査報告 / Report

An Attempt at the Transmission of Intangible Cultural Heritage Through Japan-Mongolia Regional Collaboration : A Case Study of Collaborative Practices between Hosokawa-shi Papermaking Techniques and Morin Khuur Production

地域調査報告 / Report

Intracellular Signaling Pathways for Erythropoietin-Induced Cell Proliferation in Primary Cultured Hepatocytes

The mechanisms by which erythropoietin (EPO) promotes hepatocyte proliferation in primary cultures of adult rat hepatocytes were studied. EPO stimulated cell proliferation in a time- and dose-dependent manner, significantly increasing the number of hepatocyte nuclei and DNA synthesis. EPO-induced hepatocyte proliferation was completely suppressed by specific inhibitors targeting Janus kinase 2 (JAK 2), phospholipase C (PLC), protein kinase C (PKC), intracellular Ca2+ mobilization, mitogen-activated protein kinase (MAPK)/ extracellular signal-regulated kinase (ERK) kinase (MEK), and mammalian target of rapamycin (mTOR). In contrast, inhibition of signal transducer and activator of transcription 3/5 (STAT 3/5) or granule secretion had no effect, indicating that EPO acts through a pathway distinct from the classical JAK2–STAT signaling pathway. Western blot analysis showed rapid phosphorylation of ERK 2, but not ERK 1, following EPO stimulation. In addition, EPO induced phosphorylation of PLC and C-rapidly accelerated fibrosarcoma (C-Raf), with PKC acting downstream of PLC and upstream of C-Raf. In contrast, intracellular Ca2+ concentration and activated Ras were transiently increased in hepatocytes after EPO stimulation, and EPO-induced activated Ras was significantly suppressed by the specific PKC inhibitor GF109203X. These results indicate that EPO engages the JAK2/PLC/PKC-Ca2+ signaling cascade, leading to the sequential activation of Ras, C-Raf, and ERK2, ultimately promoting hepatocyte proliferation in vitro.This is an open access article distributed under the terms of Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/). Published by The Pharmaceutical Society of Japan

Collaborative Bread Development Project by Students in the Registered Dietitian Training Program : Regional revitalization using ingredients from Saitama Prefecture and the superfood "Moringa"

地域活動ノート / Note

Development of a relative educational performance index on the National Examination for Pharmacists

薬学生が薬剤師として大学教育の成果を生かした活動をするには薬剤師国家試験合格は必須であるが，その合格率は大学間で差が大きい．入学時の学力や大学での教育成果その他の要因が影響していると考えられる．薬剤師国家試験合格率と 入学時試験学力の関連を解析し，薬剤師国家試験成績に対する大学教育の効果を定量する簡便な指標の算出を試みた．薬剤師国家試験合格率は入学時試験学力と強い相関を示した．入学時試験学力から予測される合格率と実際の合格率の差を 大学在学期間の成長度の指標（大学教育効果，REPP）として算出し，その性質を解析したところ，REPP は入学時試験学力とは相関がなく，薬剤師国家試験成績や進級率と緩やかな相関を示した．また，薬剤師国家試験合格率予測精度を高め る作用を示した．REPP は入学時試験学力とは弁別的な薬剤師国家試験成績の指標であり，薬系大学における教育の効果を測る指標として有用と考えられる