血管内皮生长因子表达与肝癌患者临床病理特征及预后的关系研究

目的:研究肝细胞肝癌(HCC)组织中血管内皮生长因子(VEGF)表达与患者临床病理特征及预后的关系。方法:采用免疫组织化学染色法检测79例在广西医科大学附属肿瘤医院行肝癌根治性切除术的HCC患者癌组织中VEGF的表达情况,分析VEGF表达与树突状细胞(DC)浸润程度、肿瘤大小、癌栓、包膜、血清AFP水平及术后肝外转移的关系,随访患者术后生存情况及肿瘤复发情况。结果:79例HCC患者中,VEGF低表达43例(54.4%),高表达36例(45.6%)。VEGF表达与DC浸润程度、肿瘤直径及血清AFP水平有关(P0.05)。VEGF高表达组2年内复发率为83.3%(30/36),明显高于VEGF低表达组的60.5%(26/43),差异有统计学意义(P0.05)。结论:VEGF与癌组织DC浸润程度、肿瘤直径及血清AFP水平有关,其在HCC组织中高表达可能增加肝癌术后短期复发风险,可作为肝癌早期复发预警指标

Transurethral balloon dilatation of the prostate: initial results, indication and complication

BPHに起因した排尿障害を有する40症例に対しlarge prostaic dilation catheterを使用した尿道拡張術を施行した.最長観察期間は22ヵ月, 平均観察期間は9.5ヵ月であった.1)術中の愁訴として, 尿意切迫感が32例にみられた.術後肉眼的血尿はほとんど全例でみられたが, 輸血などを必要とした例はなかった.2)拡張後, 残尿量は減少し, 平均尿流率, 最大尿流率も5.7から8.2 ml/sec, 10.4から15.6 ml/secへと改善していた.3) IT typeとIF typeに分類し検討すると, IF typeのBPHの方が高い臨床効果を示していた.尿閉21例中12例に留置カテーテルの抜去が可能であった.無効の症例はいずれも膀胱内に突出する中葉肥大を伴うのBPHであったTransurethral balloon dilatation therapy was performed on 40 patients with benign prostatic hypertrophy (BPH) under local anesthesia. During the procedure, urinary urgency occurred in 80% of the patients. After prostatic dilatation, macrohematuria was observed in almost all patients. The longest follow-up period after dilatation was now 22 months, and the average was 9.5 months. After treatment, residual urine volume decreased, and average flow rate and maximal flow rate improved from 5.7 and 10.4 ml/sec to 8.2 and 15.6 ml/sec, respectively. Overall clinical efficacy was 67.5%. Urethral dilatation therapy was thought to be an effective and non-invasive therapy for BPH

阿克苏河灌区棉花耐盐指标的确定/Indexes of Salt Tolerance of Cotton in Akesu River Irrigation District[J]

[目的]通过建立阿克苏河灌区棉花产量与其相应的土壤含盐量的响应关系,即棉花盐分生产函数模型:分段式线性函数模型和非线性-S型函数模型,确定该地区棉花的耐盐指标.[方法]根据3年4地大田定位观测的棉花产量和土壤盐分数据,通过线性回归分析法和非线性最小二乘法分别得出O-20 cm和O-40 cm土层的2种模型,对比分析函数模型的适用性,依据适用性更强的土层模型计算棉花的耐盐指标.[结果]分别拟合出O-20 cm和O-40cm土层的分段线性函数模型和非线性-s型函数模型,其中非线性-S型盐分生产函数模型拟合精度较高.[结论]阿克苏河灌区(0-20 cm土层)棉花的耐盐临界值、时盐极限值、减产速率最大时的土壤盐分含量、减产50%时的土壤盐分含量分别为O.302%、1.119%、O.558%、O.581%

JUNO Sensitivity on Proton Decay p→νˉK+p\to \bar\nu K^+ Searches

The Jiangmen Underground Neutrino Observatory (JUNO) is a large liquid scintillator detector designed to explore many topics in fundamental physics. In this paper, the potential on searching for proton decay in $p\to \bar\nu K^+$ mode with JUNO is investigated.The kaon and its decay particles feature a clear three-fold coincidence signature that results in a high efficiency for identification. Moreover, the excellent energy resolution of JUNO permits to suppress the sizable background caused by other delayed signals. Based on these advantages, the detection efficiency for the proton decay via $p\to \bar\nu K^+$ is 36.9% with a background level of 0.2 events after 10 years of data taking. The estimated sensitivity based on 200 kton-years exposure is $9.6 \times 10^{33}$ years, competitive with the current best limits on the proton lifetime in this channel

JUNO sensitivity on proton decay p → ν K + searches*

The Jiangmen Underground Neutrino Observatory (JUNO) is a large liquid scintillator detector designed to explore many topics in fundamental physics. In this study, the potential of searching for proton decay in the $p\to \bar{\nu} K^+$ mode with JUNO is investigated. The kaon and its decay particles feature a clear three-fold coincidence signature that results in a high efficiency for identification. Moreover, the excellent energy resolution of JUNO permits suppression of the sizable background caused by other delayed signals. Based on these advantages, the detection efficiency for the proton decay via $p\to \bar{\nu} K^+$ is 36.9% ± 4.9% with a background level of $0.2\pm 0.05({\rm syst})\pm$$0.2({\rm stat})$ events after 10 years of data collection. The estimated sensitivity based on 200 kton-years of exposure is $9.6 \times 10^{33}$ years, which is competitive with the current best limits on the proton lifetime in this channel and complements the use of different detection technologies