Analysis and Design of Multi-service Broadband Private Network Based on MSTP in Banking

为不断满足管理集中化和经营集约化发展的要求，国内大型商业银行广域网络正朝着高速化、集中化、应用多样化的综合组网方向发展。这其中，对原有网络实施接入网扁平化改造，减少网络层次结构，统一接入策略，实现汇聚扁平化、传输综合化、接入灵活化、带宽能够平滑升级的目标，成为各家商业银行面临的重大课题。 本文从大型商业银行省级分行的业务和管理需求分析出发，结合金融行业网络的专有特性，从网络承载业务的角度，根据业务数据流量的特点，对商业银行不同种类业务的数据传输需求进行分类；根据商业银行不同种类业务、不同规模营业网点的特征，对网络承载能力的功能性需求和非功能性需求进行了详细分析。比较了MSTP技术与SDH技术...In order to continue to meet development of centralized management and intensive operation, network construction of large domestic commercial banks is moving towards high-speed, centralized, diversified Wide Area Network. Among these, the access network on the original flat network is expected to reduce the network hierarchy, unify access strategy and achieve convergence flat and transmission...学位：工程硕士院系专业：软件学院_工程硕士(软件工程)学号：X200823017

Tannin dynamics during the development of propagules and adaptations to saline conditions of some mangrove species in the Jiulong River Estuary，Fujian，China

本文研究了福建九龙江口红树林自然保护区的秋茄（Kandeliacandel）﹑木榄（Bruguieragymnorrhiza）和红海榄（Rhizophorastylosa）繁殖体胎生发育过程中总酚﹑可溶缩合单宁﹑结合缩合单宁﹑总缩合单宁﹑蛋白质沉淀酚含量﹑单宁与蛋白质结合能力及缩合单宁的化学结构等的变化；同时，进行温室不同盐度梯度栽培实验，测定秋茄幼苗第二对真叶及桐花树（Aegicerascorniculatum）幼苗第一真叶张开后的各种单宁含量变化，进而探讨其抗盐适应。研究结果显示：（1）3种繁殖体发育过程中以单宁酸为标准和以纯化单宁为标准测定的总酚含量具有显著的相关性，以纯化单宁为标准的总...Changes in the total phenolics, extractable condensed tannins, protein bound condensed tannins, fibre bound condensed tannins, total condensed tannins, protein- precipitating phenolics and protein precipitation capacity were determined at different developmental stages of propagules of Kandelia candel, Bruguiera gymnorrhiza and Rhizophora stylosa in the Jiulong River Estuary, Fujian, China. In add...学位：理学硕士院系专业：生命科学学院生物学系_植物学学号：20032600

Structural Design and Optimization of Molded Pulps for Large-sized LCD

在纸浆模衬垫结构的缓冲机理研究基础上,介绍了32吋大平面液晶显示器纸浆模缓冲衬垫结构的设计方法。在充分考虑制造可行性基础上,提出了一种新型的折叠嵌套式纸浆模缓冲衬垫结构。通过仿真分析对结构进行优化,并验证所设计的衬垫结构的缓冲性能,为同类型大平面显示器纸浆模衬垫设计提供参考。Structural design method of cushions for large-sized LCD was introduced based on the study of the cushioning mechanism of molded pulp cushion structure.A new type folding and nesting molded pulp cushion structure was put forward with fully consideration of manufacturing feasibility.The structure was optimized and the cushioning performance of the cushioning structure was verified by simulation analysis.The purpose was to provide reference for structural design of cushions for large-sized LCD

Two Dimensional Ultrasonic Vibration Assisted Chemical Mechanical Grinding and Experiment on Si Wafer

为了提高材料去除率和加工通用性,本文提出了工具施加二维超声波振动辅助的化学机械磨削(CMg)复合加工方式,开发具有伸缩和弯曲两种模态的二维超声波振动子及实验装置.以单晶硅片为加工对象,进行单点切削加工轨迹特性分析,并比较不同加工模式以及加工参数对表面粗糙度和材料去除率的影响.实验结果表明,二维超声辅助下的单点切削轨迹存在更多延性加工趋势.在同样普通机床精度条件下,随着时间的增加,二维超声辅助CMg表面粗糙度明显改善,达到纳米级.较无超声情况下二维超声波辅助CMg复合加工材料去除率提高约1倍,可获得最优表面粗糙度5 nM,一维径向超声辅助加工结果次之.To improve material removal rate and machining popularity,two dimensional ultrasonic vibration assisted chemical mechanical grinding(CMG) was introduced in this paper as the combined grinding method.And two dimensional vibrators with longitudinal and bending modes and integrated experimental installation were developed.Si wafer was taken as machining material,and the experiments were carried out to examine the characteristic of machining locus using single point cutting,and the influence of different machining modes and parameters on surface roughness and material removal rate.The results show that two dimensional ultrasonic assisted single point cutting locus makes more ductile removal.When using the general-purpose machine,two dimensional ultrasonic assisted CMG can obtain better surface roughness at nanometer level as the machining time increases.Compared with conventional CMG without ultrasonic vibration the material removal rate improves by 100% and the best surface roughness is 5 nm.Two dimensional ultrasonic assisted CMG yields the best surface roughness and the largest material removal rate,and one dimensional radial ultrasonic assisted CMG is relatively backward.国家高技术研究发展计划(863计划)资助项目(2008AA042501);国家自然科学基金资助项目(50905150

基于知识图谱的药品联用建模及风险评价

目的:根据临床用药实践中的药品联用模式构建知识图谱模型,从而自动化地评价药品联用风险。方法:基于海量处方用药大数据,采用知识图谱建模方法,构建概率图模型,并利用子图搜索算法进行药品联用风险评价。结果:在某三甲医院门诊妇科的59703条真实用药处方中,随机挑选30%数据作为测试集,得到药品联用风险预测准确率达98.3%,能够有效识别合理药品联用模式。结论:基于处方大数据构建的药品联用知识图谱模型能准确地对药品联用风险进行评估,可降低人工成本,减轻药师负担,为临床药事管理提供决策依据,提高联合用药的安全性

间歇式轴向压应力对组织工程骨种子细胞的黏附增殖与成骨分化促进作用的研究

目的探究间歇式轴向压应力对组织工程骨种子细胞黏附、增殖与成骨分化能力的影响。方法构建表达绿色荧光蛋白的兔骨髓间充质干细胞(rBMSCs)作为示踪种子细胞,运用旋转细胞培养仪将松质骨支架和种子细胞共培养7 d获得组织工程骨(TEB),实验组在第7～14天施加大小10 N、频率1 Hz、4 h/d的间歇式轴向压应力刺激,对照组常规培养,14 d后胰酶消化法获取两组种子细胞并比较其黏附、增殖和成骨分化能力。采用两组独立样本t检验进行统计学分析。结果 (1)流式细胞术显示rBMSCs被成功提取分离。(2)倒置荧光显微镜及扫描电镜显示TEB中种子细胞与支架相容性良好。(3)活体荧光成像系统及扫描电镜显示应力刺激组种子细胞的生长状况要优于非应力刺激组,前者平均荧光密度及细胞数/500倍视野均大于后者,差异均具有统计学意义(平均荧光密度:(3.75±0.34)×108 vs(2.91±0.22)×108,t=2.90,P=0.04;细胞数/500倍视野:30.50±4.43 vs 21.00±5.13,t=3.14,P=0.01)。(4)细胞黏附实验显示,应力刺激组种子细胞的75﹪细胞贴壁时间短于非应力刺激组,两组时间分别为(3.00±0.41) h、(13.33±1.70)h,差异具有统计学意义(t=8.20,P <0.01),前者的最终细胞贴壁率高于后者(99.97﹪±0.34﹪vs 85.83﹪±1.18﹪),差异具有统计学意义(t=11.31,P <0.01)。(5) CCK-8检测显示,在培养第48～96 h,应力刺激组种子细胞的增殖能力优于非应力刺激组,将两者的450 nm吸光度值在第48小时(0.49±0.02、0.40±0.02)、72 h(0.76±0.07、0.64±0.04)和96 h(1.58±0.07、1.34±0.13)分别进行比较,差异均具有统计学意义(t=5.15、2.57、2.86,P均<0.01)。(6)在成骨诱导14 d后,应力刺激组种子细胞的ALP和Ca结节染色阳性率要强于非应力刺激组:两组ALP染色阳性率分别为26.73﹪±4.56﹪、16.68﹪±3.89﹪,差异具有统计学意义(t=3.33,P=0.03);两组Ca结节染色阳性率分别为41.81﹪±3.56﹪、27.40﹪±2.35﹪,差异具有统计学意义(t=3.68,P=0.02)。结论间歇性轴向压应力可促进组织工程骨种子细胞的黏附、增殖与成骨分化

Expression of the Soluble Human Fas Ligand in Dictyostelium discoideum

［中文文摘］用PCR扩增从激活的人中性粒细胞中得到的编码可溶性Fas配体胞外区中第14 1个到第2 81个氨基酸的cDNA ,将其与hCG_β信号肽片段融合到质粒MB12neo中,随后导入到盘基网柄菌AX3细胞中,得到分泌性表达hFasL的重组菌AX3_H3。为提高shFasL的表达量,对质粒pMB12neo作了改造,得到衍生质粒pMB74。利用质粒pMB74克隆表达shFasL ,得到高通量表达shFasL的重组菌AX3_pLu8。在复杂培养基HL_5C中,重组菌的细胞密度可达(1 5～2 )×10 7 mL ,AX3_H3及AX3_pLu8分泌的shFasL浓度分别为2 3 5 μg L及2 0 6 μg L。利用合成培养基SIH培养重组菌AX3_H3及AX3_pLu8,细胞密度均达到(4～5 )×10 7 mL ,shFasL浓度则分别达到111μg L和4 2 0 μg L。［英文文摘］An expression system is described for high-yield production of recombinant soluble human FasL (shFasL) in Dictyostelium discoideum cells. DNA encoding amino acids 141～281 of hFasL was PCR amplified from cDNA derived from activated human neutrophils. The resulting product was fused with a DNA fragment encoding hCG-β signal peptide and cloned in the expression vector pMB12neo. Dictyostelium strain AX3 was transfected with this plasmid, yielding a recombinant strain called AX3-pCESFL95-H3. In order to mprove the shFasL expression level , pMB12neo was optimized by replacing its transcriptional terminatorPpolyadenylation segment of the 2H3 gene with an actin8 terminatorPpolyadenylation segment , yielding derived expression vector pMB741 The recombinant Dictyostelium strain called AX3-pLu8 was generated with this new plasmid. When the recombinant cells were cultivated in a complex HL-5C medium, a cell density of (115～2) ×107PmL was reached , and the shFasL level expressed by strains AX3-pCESFL95-H3 and AX3-pLu8 was 2315 μgPL and 206μgPL , respectively. By using a newly developed synthetic medium called SIH as culture medium, higher cell density of (4～5) ×107PmL was achieved. Correspondently, 111 μgPL and 420 μgPL shFasL were secreted by recombinant strains AX3-pCESFL95-H3 and AX3-pLu8 ,respectively.国家自然科学基金资助项目(No.20306025,30370039

Study on mechanism of lead biosorption by phanerochaete chrysosporium

[中文文摘]通过电子显微镜观察和X 射线光电子能谱测定等分析手段研究了黄孢原毛平革菌 (Phanerochaetechrysosporium)对Pb2 +生物吸附的机理 .实验结果表明 ,该菌种对Pb2 + 的吸附过程是一个以表面络合反应为主要机理的物理化学吸附过程 ,同时也存在着离子交换机理,但它并非主要机理。[英文文摘]Phanerochaete chrysosporium exhibited lead adsorption capacity from aqueous solution up to 108 45 mg/g The biosorption mechanism was researched by the electron micrograph and X rays Photoelectron Spectra The experimental results showed that the main mechanism of lead biosorption was kind of physical chemical process, and metal ions were adsorbed directly on the cell surfaces In addition to surface complex reaction, ion exchange also played a role in the biosorption process, but it was not a main mechanism.国家教委留学回国人员科研启动基