Limfosarkom tankog crijeva mačke.

We describe a clinical case of a 4-year-old cat suspected to be suffering from a kidney disease, sent to our clinic by a private veterinarian. During the preceding two weeks the cat suffered from anorexia and in the past three days she had vomited food and water. Clinical examination revealed dehydration and abdominal palpation identified two solid, walnut-sized formations in the centre of the cat’s abdominal cavity. A blood sample was taken for biochemical examination and the abdominal cavity was examined by X-ray. On the basis of the results obtained a diagnostic laparotomy was performed, which established the presence of two tumorous formations protruding from jejunum. The affected part of the intestine was resected, intestinal ends were joined by end-to-end everted anastomosis and the laparotomic wound was closed using the common procedure. The cat was treated by infusions and antibiotics. The excised portion of the intestine was sent for histological examination, which identified a lymphosarcoma.Opisana je klinička slika u mačke u dobi 4 godine koja je na kliniku upućena pod sumnjom na bolest bubrega. Dva tjedna prije toga pokazivala je znakove anoreksije, a posljednja tri dana povraćala je hranu i vodu. Mačka je bila izrazito dehidrirana, a palpacijom abdomena ustanovljene su dvije čvrste tvorbe veličine oraha i to u središnjem području trbušne šupljine. Provedena je klinička i biokemijska pretraga krvi i rendgenografija abdomena. Na temelju dobivenih nalaza izvršena je dijagnostička laparotomija kojom su dokazane dvije tumorske tvorbe na taštom crijevu. Promijenjeni dio crijeva je reseciran nakon čega su krajnji dijelovi spojeni anastomozom. Mačka je nakon operacije bila liječena infuzijama i antibioticima. Odstranjen dio crijeva bio je dostavljen na histološku pretragu te je potvrđen limfosarkom

Mezoteliom perikarda u bernskoga planinskoga psa - prikaz slučaja

On the basis of a clinical case we describe the symptoms, development and surgical method used for a six-year-old Bernese mountain dog affected by mesothelioma growing out of the pericardium. We provide an overview of the incidence of the tumor, risk factors, pathogenesis and possibilities of therapy in this canine breed. In our clinical case we did not confifi rm any contact of the dog with asbestos or larger amount of pesticides, which are described as etiological factors of mesothelioma in the literature. The dog’s owner did not visit our clinic due to suspicion of a tumor, but because of the general weakness of the dog accompanied by hematuria. The owner later added that the dog had already been suffering from general weakness and depression for a longer time. The radiological examination showed a non-specific effusion in the thoracic cavity, and the ultrasound examination located the mass in the area of the heart with production of exudate into the thoracic cavity. As a result of cytological and histological examinations, a mesothelioma was detected. During thoracotomy a tumorous mass was diagnosed between the pericardium and the left thoracic wall, located on the right accessory pulmonary lobe. The tumor mass was connected with the diaphragm. Because of the bad prognosis and after consultation with the owner, the dog was euthanized. The incidence of mesothelioma in Bernese mountain dogs is described for the first time.Opisani su znakovi, razvoj i kirurška obrada mezotelioma osrčja u šestogodišnjega bernskoga planinskoga psa. Prikazan je pregled pojave tumora, rizični čimbenici, patogeneza i mogućnosti liječenja u te pasmine pasa. U anamnezi nije potvrđen ikakav dodir psa s azbestom ili većom količinom pesticida što je u literaturi opisano kao etiološki čimbenici mezotelioma. Vlasnik nije psa doveo na klinički pregled zbog sumnje na tumor već zbog opće slabosti praćene hematurijom. Naknadno je dodao da je u psa već duže vrijeme primjećivao opću slabost i potištenost. Radiološkom pretragom nije bio ustanovljen nespecifični izljev u prsnu šupljinu, a ultrazvučnom pretragom bila je ustanovljena masa u području srca s eksudatom u prsnoj šupljini. Mezoteliom je bio dijagnosticiran na osnovi citološke i histološke pretrage. Tijekom torakotomije tumorska je masa bila ustanovljena između perikarda i lijeve torakalne stijenke u području desnoga akcesornoga plućnoga režnja i bila je povezana s ošitom. Zbog loše prognoze te nakon savjetovanja s vlasnikom pas je bio eutanaziran. Ovo je prvi opis pojave mezotelioma u bernskoga planinskoga psa

Use of foods based on bee drone brood: Their sensory and microbiological evaluation and mineral composition

The aim of the work was to evaluate the safety of bee drone brood in terms of the risk of possible contamination with heavy metals, microbial contamination, and sensory acceptability. Bee drone brood dried at a temperature of 80 degrees C in a hot air oven (DBO) and lyophilized drone brood (DBL) were used. Sensory evaluation was performed on an oatmeal ball (O-B) and drone brood ball (DBO-B). For the determination of the minerals and other elements in DBO, spectrometric analysis was used. The content was as follows: Fe 60.87 mu g/g, Cu 54.83 mu g/g, Zn 257 mu g/g, Ag 82.7 mu g/g, Pb 2.1 mu g/g, Au 1.2 mu g/g, Ca 1336 mu g/g, Sr 3.13 mu g/g, Zr 1.67 mu g/g, Bi 3.87 mu g/g, Br 1.95 mu g/g. The detected content of lead in dry matter (2.1 mu g/g) was high above the limit set for crustaceans (0.4 mu g/g). By comparing microbial assay values, no statistically significant difference between freshly dried DBO and dried DBO after a month of storage was detected. Bee drone brood contains microbes far below the legal limits and it is a good source of calcium, iron, and zinc. Except for the juiciness, consumers rated O-B better than DBO-B. A statistically significant difference (p < 0.05) was found only in taste.FEKT-S-20-6215, IGA/FT/2022/004TBU in Zlin [IGA/FT/2022/004]; project BUT in Brno [FEKT-S-20-6215

Comparison of dietary oils with different polyunsaturated fatty acid n-3 and n-6 content in the rat model of cutaneous wound healing

Dietary supplementation with polyunsaturated fatty acids (PUFA) n-3 can affect cutaneous wound healing; however, recent findings demonstrate the variable extent of their influence on the quality of healing. Here, we compare the effect of several dietary oils, containing different levels of PUFA n-3 and PUFA n-6, on wound healing in the rat model. Rats were fed the feed mixture with 8% palm oil (P), safflower oil (S), fish oil (F) or Schizochytrium microalga extract (Sch) and compared to the animals fed by control feed mixture (C). Dorsal full-thickness cutaneous excisions were performed after 52 days of feeding and skin was left to heal for an additional 12 days. Histopathological analysis of skin wounds was performed, including immune cells immunolabeling and the determination of hydroxyproline amount as well as gene expression analyses of molecules contributing to different steps of the healing. Matrix-assisted-laser-desorption-ionization mass-spectrometry-imaging (MALDI-MSI) was used to determine the amount of collagen alpha-1(III) chain fragment in healing samples. Treatment by Schizochytrium extract resulted in decrease in the total wound area, in contrast to the safflower oil group where the size of the wound was larger when comparing to control animals. Diet with Schizochytrium extract and safflower oils displayed a tendency to increase the number of new vessels. The number of MPO-positive cells was diminished following any of oil treatment in comparison to the control, but their highest amount was found in animals with a fish oil diet. On the other hand, the number of CD68-positive macrophages was increased, with the most significant enhancement in the fish oil and safflower oil group. Hydroxyproline concentration was the highest in the safflower oil group but it was also enhanced in all other analyzed treatments in comparison to the control. MALDI-MSI signal intensity of a collagen III fragment decreased in the sequence C > S > Sch > P > F treatment. In conclusion, we observed differences in tissue response during healing between dietary oils, with the activation of inflammation observed following the treatment with oil containing high eicosapentaenoic acid (EPA) level (fish oil) and enhanced healing features were induced by the diet with high content of docosahexaenoic acid (DHA, Schizochytrium extract)

Požadavky zahraniční mateřské společnosti na výkaznictví dceřiné společnosti v České republice

Práce pojednává o požadavcích francouzské mateřské společnosti na výkaznictví dceřiné společnosti se sídlem v České republice, především v oblasti výsledovky a rozvahy. Práce je založena na výkaznictví skupiny THOMSON. Cílem diplomové práce je poskytnout ucelený náhled na formu vykazování lokální účetní jednotky. Závěr diplomové práce je věnován celosvětovému procesu harmonizace účetnictví a harmonizaci účetníctví z pohledu Evropské unie

Societal perception of children raised in infants´nursing homes and children´s homes

My diploma thesis titled Societal perception of children raised in infants nursing homes and children homes is research focused. The thesis is divided into the theoretical and practical parts. The theoretical part in its first chapter addresses infant institutes. The second chapter deals with children homes their categorization and covers the disadvantages of children{\crq}s homes. The following chapter is concentrated on the associations that provide help to the children from children's homes. Further, we mention the Instruction of the Ministry of Health for running of the infant institutes and children's homes for children under three years of age. Furthermore, attention is focused at groups of children that are placed in constitutional care, their characteristics and the arguments for their placing in the constitutional care. In the next part, the roles of representatives of children, inanition syndrome information, aims and purposes of the constitutional care, living conditions in these institutions and the volunteers providing help to children in such circumstances are mentioned. Next chapters discuss the existing care types of forsaken children and spare-family care system problems. Later, the constitutional care in the Czech Republic is compared to the Great Britain model. At the end of the theoretical part, we analyze the options of further dwelling and integration of the individuals. The target of this work was to determine the perception of the children from infant institutes and children{\crq}s homes by the society. In our hypotheses we anticipated that the society does not sufficient information regarding the children from infant institutes and the children's homes and that male and female opinion are different. We assumed in our other hypothesis that the society anticipates that these children are future delinquents and that the opinion of younger people were different from those of older people. We used a method of questionnaire to confirm or reject the determined hypotheses. The questionnaire consists of 19 questions. 120 questionnaires were distributed with a 100% return rate. Conclusion of the thesis comprises findings from both the theoretical and practical parts

Ověření odolnosti vláknobetonů a drátkobetonů při působení vysokých teplot

Import 26/09/2006Prezenční223 - Katedra stavebních hmot a hornického stavitelstv

The influence of HDL and LDL cholesterol, triacylglycerol, glucose, age and sex on myocardial infarction

Infarkt myokardu (IM) je akutní loţisková ischemická nekróza části myokardu vzniklá přerušením krevního zásobení. Více neţ v 90% je jeho příčinou koronární ateroskleróza s rupturou intimy a trombózou v místě plátu. Cílem diplomové práce bylo zjistit, který ze sledovaných rizikových faktorů aterosklerózy je nejvýznamnější v daném souboru pacientů. Dále byla provedena korelace mezi dvěma hlavními markery nekrózy myokardu- troponiny T a I (TnT a TnI). Pouţity byly hodnoty naměřené na automatických analyzátorech, které byly dále zpracovány softwary QC-EXPERT a STATISTICA. Získána byla data od 201 pacientů. Ke korelaci bylo pouţito 70 měření TnT a TnI. Ve skupině 45 pacientů trpících IM bylo odhaleno 73% (tj. 33 osob) se zvýšenou hladinou glykemie, 13% (tj. 6 osob) s vyšší hladinou triacylglycerolů, 20% (tj. 9 osob) s vysokou hladinou LDL cholesterolu a 28% (tj. 13 osob) s hladinou HDL cholesterolu pod doporučované minimum. Ve skupině 156 pacientů bez IM bylo zjištěno 53,8% (tj. 84 osob) se zvýšenou hladinou glykemie, 26,3% (tj. 41 osob) s vyšší hladinou triacylglycerolů, 32,7% (tj. 51 osob) s vysokou hladinou LDL cholesterolu a 21,2% (tj. 33 osob) s hladinou HDL cholesterolu pod doporučované minimum. Nejvýznamnějším RF aterosklerózy v našem souboru je tedy zvýšená glykemie (nad 6 mmol/l). Pearsonův korelační koeficient pro korelaci TnT vs TnI má hodnotu 0,59, coţ značí silnou pozitivní korelaci mezi těmito markery. Jejich význam při diagnostice IM je srovnatelný, avšak u TnI je výhodou jeho absolutní kardiospecifita. Součástí práce bylo vytvoření informačního materiálu pro pacienty nemocnice.A myocardial infarction (MI) is acute necrosis of myocardial cells due to prolonged ischaemia. It is caused by atherosclerosis in more than 90%. The aim of this work was to find which risk factor is the most important in our group of patiens. We performed the correlation between two main markers of myocardial necrosis- troponin T and I (TnT and TnI). Data was acquired from automatic analysator and evaluated in STATISTICA and QC- EXPERT softwares. It was acquired data from 201 pacients. For correlation we used 70 measurments TnT and TnI. In group of 46 patients with MI we discovered 73% (33 persons) with higher glycemia, 13% (6 p.) with higher triglycerides, 20% (9 p.) with high level of LDL cholesterol and 28% (13 p.) with HDL cholesterol level under recommended minimum. In group with 156 patients without MI it was founded 53,8% (84 persons) with elevated glycemia, 26,3% (41 p.) with elevated surface of triglycerides, 32,7% (51 p.) with high surface of LDL cholesterol and 21,2% (33 p.) with surface of HDL cholesterol under recommended minimum. The most significant risk factor in our group was higher glycemia (over 6 mmol/l). Pearson's correlation coeficient for TnT vs TnI was 0,59, which mean strong positive correlation. The mean of this markers is similar, but there is one advantage of TnI and it is it's absolute cardiospecifity. To create information papers for patients of the hospital was component of this work as well. It is available in waiting rooms of relevant wards.Katedra biologických a biochemických věd1. Prezentace výsledků diplomové práce. 2. Diskuze k posudkům vedoucího a oponenta diplomové práce. 3. Diplomantka zodpověděla všechny dotazy a připomínky k DP.Dokončená práce s úspěšnou obhajobo