Changes in salivary analytes in canine parvovirus : A high-resolution quantitative proteomic study

The present study evaluated the changes in salivary proteome in parvoviral enteritis (PVE) in dogs through a high-throughput quantitative proteomic analysis. Saliva samples from healthy dogs and dogs with severe parvovirosis that survived or perished due to the disease were analysed and compared by Tandem Mass Tags (TMT) analysis. Proteomic analysis quantified 1516 peptides, and 287 (corresponding to 190 proteins) showed significantly different abundances between studied groups. Ten proteins were observed to change significantly between dogs that survived or perished due to PVE. Bioinformatics' analysis revealed that saliva reflects the involvement of different pathways in PVE such as catalytic activity and binding, and indicates antimicrobial humoral response as a pathway with a major role in the development of the disease. These results indicate that saliva proteins reflect physiopathological changes that occur in PVE and could be a potential source of biomarkers for this disease

The double-edged sword - abused womens experiences of digital technology : Det Tveeggade Svärdet – Teknologins Betydelse för Kvinnor som Utsätts för Våld i Nära Relation

Technology has become a vital part of peoples lives. Mobile phones, smart phones, social media platforms, apps and other internet-connected devices and software have changed our way of interacting with each other, as well as managing everyday tasks. In this article, the use of such technology is discussed in relation to its integration in the lives of women who are victims of domestic violence. The study is based on interviews with 21 Swedish women, all abused by their former husband or boyfriend. The empirical data demonstrates how technology is used by the perpetrators as a means of coercive control. The analysis shows that the accessibility of digital media enables the abuser to be constantly present in the womans life, even after she has left him. However, the same technology is also important to the women, enabling them to manage victimisation, monitor the perpetrators, store evidence, obtain information, gain support and keep in touch with family and friends. This article reveals the use of technology in IPV as a double-edged sword; providing the capacity to protect and even to use as a counter-strike by victims, as well as enhancing perpetrators capacity to harm.I denna artikel diskuteras hur digital teknik används då kvinnor utsätts förvåld i en nära relation. Studien baseras på kvalitativa intervjuer med 21 svenska kvinnor som lämnat sina män efter att de blivit utsatta för våld. Analysen visar att förövarna använder digital teknik, bland annat smartatelefoner, digitala övervakningssystem, sociala medier och plattformar, för att kontrollera, hota, förfölja och övervaka kvinnorna. Även efter separation möjliggör tekniken för våldsutövare att vara närvarande iden våldsutsattas liv utan något krav på fysisk närvaro. Samtidigt gav samma teknologi de våldsutsatta kvinnorna verktyg för att hantera situationen genom att i viss mån övervaka förövaren, samla information,spara bevis, söka stöd och i akuta situationer be om hjälp. Sammantaget kan digital teknik både förlänga och underlätta kontroll och övervakning från den manliga partnern men samtidigt ge kvinnorna en viss möjlighet till kontroll. I den meningen utgör teknikenett tveeggat svärd.Funding Agencies|FORTE, The Swedish Research Council for Health, Working Life and Welfare [2016-00987]</p