3,509 research outputs found
The swiss army knife of job submission tools: grid-control
Grid-control is a lightweight and highly portable open source submission tool
that supports virtually all workflows in high energy physics (HEP). Since 2007
it has been used by a sizeable number of HEP analyses to process tasks that
sometimes consist of up 100k jobs. grid-control is built around a powerful
plugin and configuration system, that allows users to easily specify all
aspects of the desired workflow. Job submission to a wide range of local or
remote batch systems or grid middleware is supported. Tasks can be conveniently
specified through the parameter space that will be processed, which can consist
of any number of variables and data sources with complex dependencies on each
other. Dataset information is processed through a configurable pipeline of
dataset filters, partition plugins and partition filters. The partition plugins
can take the number of files, size of the work units, metadata or combinations
thereof into account. All changes to the input datasets or variables are
propagated through the processing pipeline and can transparently trigger
adjustments to the parameter space and the job submission. While the core
functionality is completely experiment independent, integration with the CMS
computing environment is provided by a small set of plugins.Comment: 8 pages, 7 figures, Proceedings for the 22nd International Conference
on Computing in High Energy and Nuclear Physic
NMR Study of CO2 Capture by Butylamine and Oligopeptide KDDE in Aqueous Solution: Capture Efficiency and Gibbs Free Energy of the Capture Reaction as a Function of PH**
We Have Been Interested in the Development of Rubisco-Based Biomimetic Systems for Reversible CO2 Capture from Air. Our Design of the Chemical CO2 Capture and Release (CCR) System is Informed by the Understanding of the Binding of the Activator CO2 (ACO2) in Rubisco (Ribulose-1,5-Bisphosphate Carboxylase/oxygenase). the Active Site Consists of the Tetrapeptide Sequence Lys-Asp-Asp-Glu (Or KDDE) and the Lys Sidechain Amine is Responsible for the CO2 Capture Reaction. We Are Studying the Structural Chemistry and the Thermodynamics of CO2 Capture based on the Tetrapeptide CH3CO−KDDE−NH2 ( KDDE ) in Aqueous Solution to Develop Rubisco Mimetic CCR Systems. Here, We Report the Results of 1H NMR and 13C NMR Analyses of CO2 Capture by Butylamine and by KDDE. the Carbamylation of Butylamine Was Studied to Develop the NMR Method and with the Protocol Established, We Were Able to Quantify the Oligopeptide Carbamylation at Much Lower Concentration. We Performed a PH Profile in the Multi Equilibrium System and Measured Amine Species and Carbamic Acid/carbamate Species by the Integration of 1H NMR Signals as a Function of PH in the Range 8≤pH≤11. the Determination of ΔG1(R) for the Reaction R−NH2+CO2 (Formula Presented.) R−NH−COOH Requires the Solution of a Multi-Equilibrium Equation System, Which Accounts for the Dissociation Constants K2 and K3 Controlling Carbonate and Bicarbonate Concentrations, the Acid Dissociation Constant K4 of the Conjugated Acid of the Amine, and the Acid Dissociation Constant K5 of the Alkylcarbamic Acid. We Show How the Multi-Equilibrium Equation System Can Be Solved with the Measurements of the Daughter/parent Ratio X, the Knowledge of the PH Values, and the Initial Concentrations [HCO3−]0 and [R-NH2]0. for the Reaction Energies of the Carbamylations of Butylamine and KDDE, Our Best Values Are ΔG1(Bu)=−1.57 Kcal/mol and ΔG1(KDDE)=−1.17 Kcal/mol. Both CO2 Capture Reactions Are Modestly Exergonic and Thereby Ensure Reversibility in an Energy-Efficient Manner. These Results Validate the Hypothesis that KDDE-Type Oligopeptides May Serve as Reversible CCR Systems in Aqueous Solution and Guide Designs for their Improvement
Acquired Factor X Deficiency in Light Chain Amyloidosis: A Report of 2 Korean Cases
Amyloidosis is a heterogeneous group of diseases in which misfolding of extracellular proteins is the pathogenic factor. Light chain amyloidosis (AL) is the most common form of amyloidosis, and the causative proteins in AL are the immunoglobulin light chains produced by clonal plasma cells. Hemorrhagic events, ranging from mild subcutaneous hemorrhage to life-threatening bleeding, account for a significant proportion of morbidities and mortality in AL patients. Deficiency of factor X from deposition into amyloid fibrils has been reported to be the most common acquired factor deficiency in AL. We herein report 2 patients with acquired factor X deficiency in AL. A 55-yr-old woman with AL had a prolonged prothrombin time (PT) and an activated partial thromboplastin time (aPTT) of 2.51 International Normalized Ratio (INR) and 75.1 sec, respectively, which were corrected on mixing with normal plasma. Factor X activity was markedly decreased at 5%. The other patient was a 67-yr-old man with AL with a PT of 1.63 INR and an aPTT of 50.3 sec, which were corrected on mixing with normal plasma. Factor X activity was decreased at 17%. Neither of the patients had apparent hemorrhagic manifestations. Identification of acquired factor deficiency and timely coagulation tests are needed in the diagnostic workup and management in AL
A Real Time Processing system for big data in astronomy: Applications to HERA
As current- and next-generation astronomical instruments come online, they will generate an unprecedented deluge of data. Analyzing these data in real time presents unique conceptual and computational challenges, and their long-term storage and archiving is scientifically essential for generating reliable, reproducible results. We present here the real-time processing (RTP) system for the Hydrogen Epoch of Reionization Array (HERA), a radio interferometer endeavoring to provide the first detection of the highly redshifted 21 cm signal from Cosmic Dawn and the Epoch of Reionization by an interferometer. The RTP system consists of analysis routines run on raw data shortly after they are acquired, such as calibration and detection of radio-frequency interference (RFI) events. RTP works closely with the Librarian, the HERA data storage and transfer manager which automatically ingests data and transfers copies to other clusters for post-processing analysis. Both the RTP system and the Librarian are public and open source software, which allows for them to be modified for use in other scientific collaborations. When fully constructed, HERA is projected to generate over 50 terabytes (TB) of data each night, and the RTP system enables the successful scientific analysis of these data
Search for direct pair production of supersymmetric partners to the τ lepton in proton–proton collisions at √s = 13 TeV
A search is presented for τ slepton pairs produced in proton–proton collisions at a center-of-mass energy of 13TeV. The search is carried out in events containing two τ leptons in the final state, on the assumption that each τ slepton decays primarily to a τ lepton and a neutralino. Events are considered in which each τ lepton decays to one or more hadrons and a neutrino, or in which one of the τ leptons decays instead to an electron or a muon and two neutrinos. The data, collected with the CMS detector in 2016 and 2017, correspond to an integrated luminosity of 77.2fb⁻¹. The observed data are consistent with the standard model background expectation. The results are used to set 95% confidence level upper limits on the cross section for τ slepton pair production in various models for τ slepton masses between 90 and 200GeV and neutralino masses of 1, 10, and 20GeV. In the case of purely left-handed τ slepton production and decay to a τ lepton and a neutralino with a mass of 1GeV, the strongest limit is obtained for a τ slepton mass of 125GeV at a factor of 1.14 larger than the theoretical cross section
Inclusive jet cross sections and dijet correlations in photoproduction at HERA
Inclusive jet cross sections in photoproduction for events containing a
meson have been measured with the ZEUS detector at HERA using an integrated
luminosity of . The events were required to have a
virtuality of the incoming photon, , of less than 1 GeV, and a
photon-proton centre-of-mass energy in the range . The measurements are compared with next-to-leading-order (NLO) QCD
calculations. Good agreement is found with the NLO calculations over most of
the measured kinematic region. Requiring a second jet in the event allowed a
more detailed comparison with QCD calculations. The measured dijet cross
sections are also compared to Monte Carlo (MC) models which incorporate
leading-order matrix elements followed by parton showers and hadronisation. The
NLO QCD predictions are in general agreement with the data although differences
have been isolated to regions where contributions from higher orders are
expected to be significant. The MC models give a better description than the
NLO predictions of the shape of the measured cross sections.Comment: 43 pages, 12 figures, charm jets ZEU
Measurement of the Lifetime Difference Between B_s Mass Eigenstates
We present measurements of the lifetimes and polarization amplitudes for B_s
--> J/psi phi and B_d --> J/psi K*0 decays. Lifetimes of the heavy (H) and
light (L) mass eigenstates in the B_s system are separately measured for the
first time by determining the relative contributions of amplitudes with
definite CP as a function of the decay time. Using 203 +/- 15 B_s decays, we
obtain tau_L = (1.05 +{0.16}/-{0.13} +/- 0.02) ps and tau_H = (2.07
+{0.58}/-{0.46} +/- 0.03) ps. Expressed in terms of the difference DeltaGamma_s
and average Gamma_s, of the decay rates of the two eigenstates, the results are
DeltaGamma_s/Gamma_s = (65 +{25}/-{33} +/- 1)%, and DeltaGamma_s = (0.47
+{0.19}/-{0.24} +/- 0.01) inverse ps.Comment: 8 pages, 3 figures, 2 tables; as published in Physical Review Letters
on 16 March 2005; revisions are for length and typesetting only, no changes
in results or conclusion
Measurement of B(t->Wb)/B(t->Wq) at the Collider Detector at Fermilab
We present a measurement of the ratio of top-quark branching fractions R= B(t
-> Wb)/B(t -> Wq), where q can be a b, s or a d quark, using lepton-plus-jets
and dilepton data sets with integrated luminosity of ~162 pb^{-1} collected
with the Collider Detector at Fermilab during Run II of the Tevatron. The
measurement is derived from the relative numbers of t-tbar events with
different multiplicity of identified secondary vertices. We set a lower limit
of R > 0.61 at 95% confidence level.Comment: 7 pages, 2 figures, published in Physical Review Letters; changes
made to be consistent with published versio
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