Investigating context-aware clues to assist navigation for visually impaired people

It is estimated that 7.4 million people in Europe are visually impaired [1]. Limitations of traditional mobility aids (i.e. white canes and guide dogs) coupled with a proliferation of context-aware technologies (e.g. Electronic Travel Aids, Global Positioning Systems and Geographical Information Systems), have stimulated research and development into navigational systems for the visually impaired. However, current research appears very technology focused, which has led to an insufficient appreciation of Human Computer Interaction, in particular task/requirements analysis and notions of contextual interactions. The study reported here involved a smallscale investigation into how visually impaired people interact with their environmental context during micro-navigation (through immediate environment) and/or macro-navigation (through distant environment) on foot. The purpose was to demonstrate the heterogeneous nature of visually impaired people in interaction with their environmental context. Results from a previous study involving sighted participants were used for comparison. Results revealed that when describing a route, visually impaired people vary in their use of different types of navigation clues - both as a group, when compared with sighted participants, and as individuals. Usability implications and areas for further work are identified and discussed

Enhanced Accessibility for People with Disabilities Living in Urban Areas

[Excerpt] People with disabilities constitute a significant proportion of the poor in developing countries. If internationally agreed targets on reducing poverty are to be reached, it is critical that specific measures be taken to reduce the societal discrimination and isolation that people with disabilities continue to face. Transport is an important enabler of strategies to fight poverty through enhancing access to education, employment, and social services. This project aims to further the understanding of the mobility and access issues experienced by people with disabilities in developing countries, and to identify specific steps that can be taken to start addressing problems. A major objective of the project is to compile a compendium of guidelines that can be used by government authorities, advocacy groups, and donor/loan agencies to improve the access of people with disabilities to transport and other services in urban areas

Enactivism and ethnomethodological conversation analysis as tools for expanding Universal Design for Learning: the case of visually impaired mathematics students

Blind and visually impaired mathematics students must rely on accessible materials such as tactile diagrams to learn mathematics. However, these compensatory materials are frequently found to offer students inferior opportunities for engaging in mathematical practice and do not allow sensorily heterogenous students to collaborate. Such prevailing problems of access and interaction are central concerns of Universal Design for Learning (UDL), an engineering paradigm for inclusive participation in cultural praxis like mathematics. Rather than directly adapt existing artifacts for broader usage, UDL process begins by interrogating the praxis these artifacts serve and then radically re-imagining tools and ecologies to optimize usability for all learners. We argue for the utility of two additional frameworks to enhance UDL efforts: (a) enactivism, a cognitive-sciences view of learning, knowing, and reasoning as modal activity; and (b) ethnomethodological conversation analysis (EMCA), which investigates participants’ multimodal methods for coordinating action and meaning. Combined, these approaches help frame the design and evaluation of opportunities for heterogeneous students to learn mathematics collaboratively in inclusive classrooms by coordinating perceptuo-motor solutions to joint manipulation problems. We contextualize the thesis with a proposal for a pluralist design for proportions, in which a pair of students jointly operate an interactive technological device

Lighting the way through the home: development of early braille literacy

Emergent braille literacy is the earliest phase of language development where children, from infancy, are exposed to 'direct, repeated and meaningful interactions with braille literacy materials and events' (Rex, Koenig, Wormsley, & Baker, 1995, p.10). Activities such as shared reading of tactile books, scribbling on the braille machine, joint engagement in nursery rhymes, songs and chants help infants acquire cognitive concepts and develop physical skills to engage in braille. The process leads to the early development of literacy concepts including speaking, listening,reading and writing, as a foundation for braille literacy (Drezek, 1999)

Servicescapes seen by visually impaired travellers : Time-geography approach to servicescape research

Knowledge gaps remain in the study of servicescapes, since existing research on servicescapes tends to ignore major advances in the understanding of space and time as social phenomena. One aspect that particularly requires further study is how emerging constraints influence customers’ interactions with organized service places. The time-geography approach was therefore applied to the current servicescape research to help to identify various constraints that blind and visually disabled persons (VIPs) experienced in a certain service place and time. A complementary usage of the concept of tactics illustrated how constrained customers responded to the constraints. The overall research question - How do blind and visually impaired persons act and move in hospitality servicescapes? – was explored empirically through individual and focus group interviews and go-along observations of 56 blind and VIPs during 3.5 years. The study population was composed of residents of Sweden, Kazakhstan, and Germany. The analysis was organized into two themes – Competition of space-time projects and Tactical behavior: evaluating, mapping, and networking. This was followed by a discussion of the analysis under the two headings A scarcity of resources and A struggle for resources. This book concluded that emerging constraints are not only “created by” the organization of servicescapes, but are also due to the customers’ insufficient capabilities. The outcome of an individual’s action in service place depends on customer’s capability to overcome unexpected constraints and available resources, such as time and an access to service offerings. Some of the key findings that emerged were that blind and VIPs were not passive recipients of services but rather developed tactical strategies to navigate within poorly organized servicescapes. In so concluding the book suggests that servicescape is a place of dynamic interplay between emerging constraints and the tactical behaviors of the constrained customers

The Hidden Though Flourishing Justification of Intellectual Property Laws: Distributive Justice, National Versus International Approaches

Bu çalışmada, Gökkuşağı alabalıklarında enfeksiyonoluşturan Ichthyophthirius multifiliis’infarklı bölgelerden izole edilmiş saha suşlarının genotipik yapıları temelindeimmundominant özellik gösteren rekombinant immobilizan antijenlerini(i-antijen) kodlayan genlerin bakteriyel ekspresyon sistemine klonlanarakeksprese ve karakterize edilmeleri, antijenik profillerinin ortaya çıkarılmasıve aşı adayı olabilecek rekombinant antijenlerin elde edilmesi amaçlanmıştır.&nbsp;Çalışmada 2018 ve 2019 yıllarının Temmuz ve Ağustos ayları arasında Gökkuşağıalabalığı yetiştiriciliğinin yoğun yapıldığı Samsun, Rize, Kayseri, Elazığ,Burdur, Antalya ve Muğla illerinde bulunan işletmeler ziyaret edilerek balıkpopülasyonları üzerinde saha araştırmaları yürütülmüş ve I. multifiliis ile enfekte bulunan balıklardan ilgili protokolleregöre izolasyon gerçekleştirilmiştir. Laboratuvara uygun solüsyonlar ve soğukzincir altında intikal ettirilen örneklerden cDNA ve gDNA izolasyonlarıgerçekleştirilmiştir. I. multifiliis i-antijengen lokusunun amplifikasyonu amacıyla optimum primer dizaynı için ön çalışmalaryürütülmüş ve hedef gen bölgeleri uygun amplifikasyon koşullarında PCR’daçoğaltılmıştır. Elde edilen amplikonlar agaroz jel üzerinden saflaştırılmıştır.Multiple gen lokusu sekanslarının belirlenebilmesi amacıyla ilgili pürifiyeamplikonlar pJET 1.2 plazmit vektörüne CloneJET PCR cloning kit (Thermo FisherScientific) kullanılarak klonlanmış ve katı besi yerinde belirlenenkolonilerden rekombinant plazmid DNA izolasyonları gerçekleştirilmiştir. Rekombinantplazmidler spesifik primerlerle çift yönlü olarak sekanslanmış vekromotogramlar De Novo Assemble üzerinden işlenerek hedef insert sekanslarvektör plazmid DNA’sı içerisinden çıkarılmış ve konsensüs sekanslar eldeedilmiştir. İlgili primerlerin i-antijen gen lokusu içerisinde çoğalttığı fragmentlerinbelirlenebilmesi amacıyla PCR ürünleri ayrıca yeni nesil dizileme teknolojisi (NGS)kullanılarak işlenmiş ve elde edilen dizilimlerin gen veri tabanlarındakimevcut tüm i-antijen gen lokusları ile filogenetik ilişkileri araştırılmıştır.Tüm bu araştırmalar sonucu karakterize edilen i-antijen genlerinin ekspreseettiği proteinlerin rekombinant olarak eldesi için çalışmalargerçekleştirilmiştir. Aşı adayı potansiyeli olabilecek bazı lokusların bakteriyelekspresyon sistemine aktarımı için kodon optimizasyonları yapılarak pET-32a(+)ekspresyon plazmid DNA’sına (Novagen) klonlanması gerçekleştirilmiştir. Eldeedilen rekombinant plazmitler E. colikompotent BL21(DE3) hücrelerine transforme edilerek optimum koşullardaekspresyon çalışmaları yürütülmüş ve ekspresyon etkinliği SDS-PAGE ve WesternBlot analizleri ile belirlenmiştir. Eksprese edilen rekombinant i-antijenproteinleri afinite kromotografi kulanılarak saflaştırılmış ve immunreaktiflikleri Western Blot analizleri ile tespit edilmiştir.&nbsp;Çalışmada,Elazığ, Rize ve Muğla illerinde ziyaret edilen işletmelerdeki Gökkuşağıalabalıklarında deri ve solungaçlarından hazırlanan preparatların mikroskobikincelemeleri ile I. multifiliisenfeksiyonunun yaygın olduğu görülmüştür. İlgili bölgelerden elde edilen I. multifiliis suşlarına ait cDNA vegDNA izolatlarının i-antijen gen lokusunun dizayn edilen pirmerlerle PCR’daamplifiye edilmesi sonucu 1200-1300 bp büyüklüğünde amplikonlar saptanmıştır.Pürifiye amplikonların klonlanması sonucu ilgili izolatlara ait açık okumaçerçevesi (ORF) sekanslarının analizinde birbirleriyle %38,3-58,8 arasındafarklılık gösteren 4 farklı i-antijen izoformu tespit edilmiştir. Bu izoformlararasında bir antijenik lokusun (ImulTR1-iant) her üç ildeki alabalıkpopülasyonlarından izole edilen I.multifiliis suşlarında da var olduğu NGS analizlerinde görülmüştür.ImulTR1-iant ORF sekansı ayrıca Amerika Birleşik Devletleri’nde alabalıklardanizole edilmiş bir i-antijen izoformuyla %83,3 identiklik gösterirken, diğertespit edilen izoformlara ait sekansların GenBank veri tabanında mevcuti-antijen sekanslarından oldukça farklı olduğu belirlenmiştir. Araştırmadarekaombinant i-antijen eldesi için yaygın belirlenen ImulTR1-iant izolatıüzerinden analizler yürütülmüştür. Bu izoformu kodlayan gen bölgesinin 1263bpbüyüklüğünde olduğu ve ORF’nin 420 amino asitten teşekkül ettiğibelirlenmiştir. ORF amino asit sekanslarının in-slico analizlerde 42,552 kDabüyüklüğünde bir proteini eksprese ettiği, bu proteinin sitoplazmik olduğu vetransmembran bölge içermediği tespit edilmiştir. Ayrıca ilgili ORF sekansıiçerisinde uzunluğu 7-22aa arasında değişen 21 antijenik bölge olduğubelirlenmiştir. Kodon optimizasyonu yapılmış olan ImulTR1-iant izoformuna ait pET-32a(+)rekombinant plazmitinin E. colikompotent BL21(DE3) hücrelerine transformasyonu ve ekspresyonu sonrasındayapılan SDS-PAGE analizlerinde in-silico analiz sonuçlarına paralel olarakyaklaşık 43kDa’luk protein jel üzerinde görüntülenmiştir. İlgili rekombinantprotein afinite kromotografide HisTrap FF crude (GE Healthcare) kolonlarıkullanılarak saflaştırılmış ve pürifiye rekombinant antijenin immun-reaktifliğiWestern-Blot analizleriyle gösterilmiştir.&nbsp;ErciyesÜniversitesi Bilimsel Araştırma Projeleri Birimi tarafından TOA-2017-7742 kodnumarasıyla desteklenen bu çalışma ile Türkiye’de gökkuşağı alabalıklarındasorun oluşturan ve ekonomik kayıplara yol açan I. multifiliis suşlarına karşı biyoteknolojik aşı geliştirilmesinoktasında aşı adayı olabilecek immobilizan antijenler üzerine özgün veriler sağlanmıştır.Elde edilen aşı adayı rekombinant antijenlerin etkinliğini ortaya koymanoktasında laboratuvar ve saha şartlarında immunizasyon ve çelınç enfeksiyondenemeleri için yeni proje çalışmaları planlanmaktadır.</style

Helping a visually impaired student to improve her social interaction skills at Andrés Bello University, Viña del Mar, Chile : an action research

Tesis (Pedagogía en Inglés)During the last decade, inclusion that is “Something which cannot be done to people, it is something in which people are actively involved” (Norwich, 1999), has been used by different educational institutions to define or highlight their programs and as a matter of promoting a very comprehensive education. That is why an action research was conducted, whose aim is to study and improve the social interaction between a visually impaired student and her professors and peers within the English Pedagogy Program from a university in the city of Viña del Mar. In this thesis project, several people who are part of the daily life of the subject of the study contributed to this thesis project by providing relevant information. These people were professors, previous and current classmates and family members who decided to participate in a voluntarily and active form. In order to collect the information from a qualitative nature, focus groups, semi-structured interviews, questionnaires and observations were used as instruments. Moreover, more support and guidance were delivered by professionals from the educational and medical fields, i.e a psychology and a psychopedagogue. These experts provided techniques in order to reach the objective of this research. In terms of results, these were unexpected because they changed the researchers’ perspectives and helped them to understand a reality that was present but, was not taken into account. After analyzing the results obtained from the strategies applied in the action plan, the researchers came into the conclusion that the subject improved her social interaction skills thanks to the different techniques that we applied with her. However, it was found out that the context played a key role in the interaction between the classmates and the subject because the dysfunctional characteristics of the peers made the student to react different to them as she interacted with the researchers.Durante la última década, inclusión que se refiere a “Una acción la cual no puede ser realizada por personas, es algo en que las personas están activamente envueltas” (Norwich, 1999) (Traducido por Ivette Aguirre, Camila Fernández, Bárbara Melo y Bastián Mendoza), ha sido utilizado por diferentes instituciones educacionales para definir o destacar sus programas como una manera de promover una educación completa. Por esta razón se llevó a cabo una investigación acción la cual pretende investigar y mejorar la interacción social entre un estudiante con dificultades visuales y sus profesores y compañeros en un programa de pregrado de una universidad en la región de Viña del Mar. Varias personas los cuales forman parte activa en el quehacer diario del sujeto de estudio contribuyeron con información relevante para esta investigación. Estos fueron profesores, compañeros, ex compañeros y familiares, quienes aceptaron participar de forma voluntaria y activa. Para recolectar la información de naturaleza cualitativa, se utilizó focos grupales, entrevistas semi-estructuradas, cuestionarios y observaciones como instrumentos. Además, más apoyo y guía fue entregada por parte de profesionales en el área de la educación y la salud como una psicóloga y psicopedagoga. Estas personas aportaron técnicas para el desarrollo del objetivo de nuestra investigación. En tema de resultados, fueron sorprendentes porque cambiaron mucho la perspectiva de los investigadores y ayudaron a entender una realidad que estaba presente pero no se había tomado en cuenta. Después de analizar los resultados obtenidos por las estrategias aplicadas en el plan de acción, los investigadores llegaron a la conclusión de que el sujeto mejoró en sus habilidades de interacción social gracias a las diferentes técnicas que se trabajaron con ella. Aunque, se encontró que el contexto juega un rol principal en la interacción entre los compañeros y la estudiante debido a que las características disfuncionales de los compañeros hicieron que la estudiante reaccionara diferente con ellos as que como interactuó con los investigadores