An Implantable Low Pressure Biosensor Transponder

The human body’s intracranial pressure (ICP) is a critical element in sustaining healthy blood flow to the brain while allowing adequate volume for brain tissue within the relatively rigid structure of the cranium. Disruptions in the body’s maintenance of intracranial pressure are often caused by hemorrhage, tumors, edema, or excess cerebral spinal fluid resulting in treatments that are estimated to globally cost up to approximately five billion dollars annually. A critical element in the contemporary management of acute head injury, intracranial hemorrhage, stroke, or other conditions resulting in intracranial hypertension, is the real-time monitoring of ICP. Currently such monitoring can only take place short-term within an acute care hospital, is prone to measurement drift, and is comprised of externally tethered pressure sensors that are temporarily implanted into the brain, thus carrying a significant risk of infection. To date, reliable, low drift, completely internalized, long-term ICP monitoring devices remain elusive. In addition to being safer and more reliable in the short-term, such a device would expand the use of ICP monitoring for the management of chronic diseases involving ICP hypertension and further expand research into these disorders. This research studies the current challenges of existing ICP monitoring systems and investigates opportunities for potentially allowing long-term implantable bio-pressure sensing, facilitating possible improvements in treatment strategies. Based upon the research, this thesis evaluates piezo-resistive strain sensing for low power, sub-millimeter of mercury resolution, in application to implantable intracranial pressure sensing

Advanced sensors technology survey

This project assesses the state-of-the-art in advanced or 'smart' sensors technology for NASA Life Sciences research applications with an emphasis on those sensors with potential applications on the space station freedom (SSF). The objectives are: (1) to conduct literature reviews on relevant advanced sensor technology; (2) to interview various scientists and engineers in industry, academia, and government who are knowledgeable on this topic; (3) to provide viewpoints and opinions regarding the potential applications of this technology on the SSF; and (4) to provide summary charts of relevant technologies and centers where these technologies are being developed

Design of a five-axis ultra-precision micro-milling machine—UltraMill. Part 1: Holistic design approach, design considerations and specifications

High-accuracy three-dimensional miniature components and microstructures are increasingly in demand in the sector of electro-optics, automotive, biotechnology, aerospace and information-technology industries. A rational approach to mechanical micro machining is to develop ultra-precision machines with small footprints. In part 1 of this two-part paper, the-state-of-the-art of ultra-precision machines with micro-machining capability is critically reviewed. The design considerations and specifications of a five-axis ultra-precision micro-milling machine—UltraMill—are discussed. Three prioritised design issues: motion accuracy, dynamic stiffness and thermal stability, formulate the holistic design approach for UltraMill. This approach has been applied to the development of key machine components and their integration so as to achieve high accuracy and nanometer surface finish

Optically controlled phased-array antenna technology for space communication systems

Using MMICs in phased-array applications above 20 GHz requires complex RF and control signal distribution systems. Conventional waveguide, coaxial cable, and microstrip methods are undesirable due to their high weight, high loss, limited mechanical flexibility and large volume. An attractive alternative to these transmission media, for RF and control signal distribution in MMIC phased-array antennas, is optical fiber. Presented are potential system architectures and their associated characteristics. The status of high frequency opto-electronic components needed to realize the potential system architectures is also discussed. It is concluded that an optical fiber network will reduce weight and complexity, and increase reliability and performance, but may require higher power

Technology Independent Synthesis of CMOS Operational Amplifiers

Analog circuit design does not enjoy as much automation as its digital counterpart. Analog sizing is inherently knowledge intensive and requires accurate modeling of the different parametric effects of the devices. Besides, the set of constraints in a typical analog design problem is large, involving complex tradeoffs. For these reasons, the task of modeling an analog design problem in a form viable for automation is much more tedious than the digital design. Consequently, analog blocks are still handcrafted intuitively and often become a bottleneck in the integrated circuit design, thereby increasing the time to market. In this work, we address the problem of automatically solving an analog circuit design problem. Specifically, we propose methods to automate the transistor-level sizing of OpAmps. Given the specifications and the netlist of the OpAmp, our methodology produces a design that has the accuracy of the BSIM models used for simulation and the advantage of a quick design time. The approach is based on generating an initial first-order design and then refining it. In principle, the refining approach is a simulated-annealing scheme that uses (i) localized simulations and (ii) convex optimization scheme (COS). The optimal set of input variables for localized simulations has been selected by using techniques from Design of Experiments (DOE). To formulate the design problem as a COS problem, we have used monomial circuit models that are fitted from simulation data. These models accurately predict the performance of the circuit in the proximity of the initial guess. The models can also be used to gain valuable insight into the behavior of the circuit and understand the interrelations between the different performance constraints. A software framework that implements this methodology has been coded in SKILL language of Cadence. The methodology can be applied to design different OpAmp topologies across different technologies. In other words, the framework is both technology independent and topology independent. In addition, we develop a scheme to empirically model the small signal parameters like \u27gm\u27 and \u27gds\u27 of CMOS transistors. The monomial device models are reusable for a given technology and can be used to formulate the OpAmp design problem as a COS problem. The efficacy of the framework has been demonstrated by automatically designing different OpAmp topologies across different technologies. We designed a two-stage OpAmp and a telescopic OpAmp in TSMC025 and AMI016 technologies. Our results show significant (10–15%) improvement in the performance of both the OpAmps in both the technologies. While the methodology has shown encouraging results in the sub-micrometer regime, the effectiveness of the tool has to be investigated in the deep-sub-micron technologies

Linear Operation of Switch-Mode Outphasing Power Amplifiers

Radio transceivers are playing an increasingly important role in modern society. The ”connected” lifestyle has been enabled by modern wireless communications. The demand that has been placed on current wireless and cellular infrastructure requires increased spectral efficiency however this has come at the cost of power efficiency. This work investigates methods of improving wireless transceiver efficiency by enabling more efficient power amplifier architectures, specifically examining the role of switch-mode power amplifiers in macro cell scenarios. Our research focuses on the mechanisms within outphasing power amplifiers which prevent linear amplification. From the analysis it was clear that high power non-linear effects are correctable with currently available techniques however non-linear effects around the zero crossing point are not. As a result signal processing techniques for suppressing and avoiding non-linear operation in low power regions are explored. A novel method of digital pre-distortion is presented, and conventional techniques for linearisation are adapted for the particular needs of the outphasing power amplifier. More unconventional signal processing techniques are presented to aid linearisation of the outphasing power amplifier, both zero crossing and bandwidth expansion reduction methods are designed to avoid operation in nonlinear regions of the amplifiers. In combination with digital pre-distortion the techniques will improve linearisation efforts on outphasing systems with dynamic range and bandwidth constraints respectively. Our collaboration with NXP provided access to a digital outphasing power amplifier, enabling empirical analysis of non-linear behaviour and comparative analysis of behavioural modelling and linearisation efforts. The collaboration resulted in a bench mark for linear wideband operation of a digital outphasing power amplifier. The complimentary linearisation techniques, bandwidth expansion reduction and zero crossing reduction have been evaluated in both simulated and practical outphasing test benches. Initial results are promising and indicate that the benefits they provide are not limited to the outphasing amplifier architecture alone. Overall this thesis presents innovative analysis of the distortion mechanisms of the outphasing power amplifier, highlighting the sensitivity of the system to environmental effects. Practical and novel linearisation techniques are presented, with a focus on enabling wide band operation for modern communications standards

Digital predistortion of RF amplifiers using baseband injection for mobile broadband communications

Radio frequency (RF) power amplifiers (PAs) represent the most challenging design parts of wireless transmitters. In order to be more energy efficient, PAs should operate in nonlinear region where they produce distortion that significantly degrades the quality of signal at transmitter’s output. With the aim of reducing this distortion and improve signal quality, digital predistortion (DPD) techniques are widely used. This work focuses on improving the performances of DPDs in modern, next-generation wireless transmitters. A new adaptive DPD based on an iterative injection approach is developed and experimentally verified using a 4G signal. The signal performances at transmitter output are notably improved, while the proposed DPD does not require large digital signal processing memory resources and computational complexity. Moreover, the injection-based DPD theory is extended to be applicable in concurrent dual-band wireless transmitters. A cross-modulation problem specific to concurrent dual-band transmitters is investigated in detail and novel DPD based on simultaneous injection of intermodulation and cross-modulation distortion products is proposed. In order to mitigate distortion compensation limit phenomena and memory effects in highly nonlinear RF PAs, this DPD is further extended and complete generalised DPD system for concurrent dual-band transmitters is developed. It is clearly proved in experiments that the proposed predistorter remarkably improves the in-band and out-of-band performances of both signals. Furthermore, it does not depend on frequency separation between frequency bands and has significantly lower complexity in comparison with previously reported concurrent dual-band DPDs

Radiation pyrometer for gas turbine blades

A turbine blade temperature measuring system for liquid oxygen turbopumps is reported. The system includes a three mode, two-input optical signal processor, interconnecting cable, and four sensor heads. Two of the heads are aperture type, while the other two are lens type. This system is applicable to a temperature range of 1400 to 2200 F

Design and demonstration of digital pre-distortion using software defined radio

Abstract. High data rates for large number of users set tight requirements for signal quality measured in terms of error vector magnitude (EVM). In radio transmitters, nonlinear distortion dominated by power amplifiers (PAs) often limits the achievable EVM. However, the linearity can be improved by linearization techniques. Digital pre-distortion (DPD) is one of these widely used linearization techniques for an effective distortion reduction over a wide bandwidth. In DPD, the nonlinearity of the transmitter is pre-compensated in the digital domain to achieve linear output. Moreover, DPD is used to enable PAs to operate in the power-efficient region with a decent linearity. As we are moving towards millimetre-wave frequencies to enable the wideband communications, the design of the DPD algorithm must be optimized in terms of performance and power consumption. Moreover, continuous development of wireless infrastructure motivates to make research on programmable and reconfigurable platforms in order to decrease the demonstration cost and time, especially for the demonstration purposes. This thesis illustrates and presents how software defined radio (SDR) platforms can be used to demonstrate DPD. Universal software defined peripheral (USRP) X300 is a commercial software defined radio (SDR) platform. The chosen model, X300, has two independent channels equipped with individual transceiver cards. SIMULINK is used to communicate with the device and the two channels of X300 are used as transmitter and receiver simultaneously in full-duplex mode. Hence, a single USRP device is acting as an operational transmitter and feedback receiver, simultaneously. The implemented USRP design consists of SIMULINK based transceiver design and lookup table based DPD in which the coefficients are calculated in MATLAB offline. An external PA, i.e. ZFL-2000+ together with a directional coupler and attenuator are connected between the TX/RX port and RX2 port to measure the nonlinearity. The nonlinearity transceiver is measured with and without the external PA. The experimental results show decent performance for linearization by using the USRP platform. However, the results differ widely due to the used USRP transceiver parameterization and PA operational point. The 16 QAM test signal with 500 kHz bandwidth is fed to the USRP transmit chain. As an example, the DPD algorithm improves the EVM from 7.6% to 2.1% and also the ACPR is reduced around 10 dB with the 16 QAM input signal where approximately + 2.2 dBm input power applied to the external PA