AES-EPO study program, volume II Final study report

Packaging, machine organization, error detection, and fabrication and test in determining solution to long-term and time-critical reliability of Apollo command module guidance-control compute

Design of a fault tolerant airborne digital computer. Volume 1: Architecture

This volume is concerned with the architecture of a fault tolerant digital computer for an advanced commercial aircraft. All of the computations of the aircraft, including those presently carried out by analogue techniques, are to be carried out in this digital computer. Among the important qualities of the computer are the following: (1) The capacity is to be matched to the aircraft environment. (2) The reliability is to be selectively matched to the criticality and deadline requirements of each of the computations. (3) The system is to be readily expandable. contractible, and (4) The design is to appropriate to post 1975 technology. Three candidate architectures are discussed and assessed in terms of the above qualities. Of the three candidates, a newly conceived architecture, Software Implemented Fault Tolerance (SIFT), provides the best match to the above qualities. In addition SIFT is particularly simple and believable. The other candidates, Bus Checker System (BUCS), also newly conceived in this project, and the Hopkins multiprocessor are potentially more efficient than SIFT in the use of redundancy, but otherwise are not as attractive

Numerical aerodynamic simulation facility feasibility study

There were three major issues examined in the feasibility study. First, the ability of the proposed system architecture to support the anticipated workload was evaluated. Second, the throughput of the computational engine (the flow model processor) was studied using real application programs. Third, the availability reliability, and maintainability of the system were modeled. The evaluations were based on the baseline systems. The results show that the implementation of the Numerical Aerodynamic Simulation Facility, in the form considered, would indeed be a feasible project with an acceptable level of risk. The technology required (both hardware and software) either already exists or, in the case of a few parts, is expected to be announced this year. Facets of the work described include the hardware configuration, software, user language, and fault tolerance

RAID Organizations for Improved Reliability and Performance: A Not Entirely Unbiased Tutorial (1st revision)

RAID proposal advocated replacing large disks with arrays of PC disks, but as the capacity of small disks increased 100-fold in 1990s the production of large disks was discontinued. Storage dependability is increased via replication or erasure coding. Cloud storage providers store multiple copies of data obviating for need for further redundancy. Varitaions of RAID based on local recovery codes, partial MDS reduce recovery cost. NAND flash Solid State Disks - SSDs have low latency and high bandwidth, are more reliable, consume less power and have a lower TCO than Hard Disk Drives, which are more viable for hyperscalers.Comment: Submitted to ACM Computing Surveys. arXiv admin note: substantial text overlap with arXiv:2306.0876

Fault-Tolerant Computing: An Overview

Coordinated Science Laboratory was formerly known as Control Systems LaboratoryNASA / NAG-1-613Semiconductor Research Corporation / 90-DP-109Joint Services Electronics Program / N00014-90-J-127

INHIBITING HEPATITIS B VIRUS GENE EXPRESSION WITH HAMMERHEAD RIBOZYMES THAT TARGET THE HBx OPEN READING FRAME

A thesis submitted to the Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, in fulfilment of the requirements for the degree of Doctor of Philosophy Johannesburg, 2002Hepatitis B virus (HBV) infection is endemic to several populous regions and is often complicated by cirrhosis and hepatocellular carcinoma (HCC). Present treatment of chronic HBV infection is usually ineffective and novel therapeutic approaches are an important medical objective. The X open reading frame (ORF) of HBV, HBx, is a conserved sequence that overlaps with the polymerase ORF and viral c/'s-elements, and is present within all viral transcripts. In addition, the HBx ORF encodes a 17 kDa transactivator protein, HBx, which is required for the establishment of viral infection and has been implicated in HBV-associated hepatocarcinogenesis. The HBx sequence thus represents a compelling target for applying nucleic acid hybridisation-based therapeutic agents for the inhibition of HBV gene expression and replication.IT201

High Availability and Scalability of Mainframe Environments using System z and z/OS as example

Mainframe computers are the backbone of industrial and commercial computing, hosting the most relevant and critical data of businesses. One of the most important mainframe environments is IBM System z with the operating system z/OS. This book introduces mainframe technology of System z and z/OS with respect to high availability and scalability. It highlights their presence on different levels within the hardware and software stack to satisfy the needs for large IT organizations

Study of spaceborne multiprocessing, phase 1

Multiprocessing computer organizations and their application to future space mission

Studies of disk arrays tolerating two disk failures and a proposal for a heterogeneous disk array

There has been an explosion in the amount of generated data in the past decade. Online access to these data is made possible by large disk arrays, especially in the RAID (Redundant Array of Independent Disks) paradigm. According to the RAID level a disk array can tolerate one or more disk failures, so that the storage subsystem can continue operating with disk failure(s). RAID 5 is a single disk failure tolerant array which dedicates the capacity of one disk to parity information. The content on the failed disk can be reconstructed on demand and written onto a spare disk. However, RAID5 does not provide enough protection for data since the data loss may occur when there is a media failure (unreadable sectors) or a second disk failure during the rebuild process. Due to the high cost of downtime in many applications, two disk failure tolerant arrays, such as RAID6 and EVENODD, have become popular. These schemes use 2/N of the capacity of the array for redundant information in order to tolerate two disk failures. RM2 is another scheme that can tolerate two disk failures, with slightly higher redundancy ratio. However, the performance of these two disk failure tolerant RAID schemes is impaired, since there are two check disks to be updated for each write request. Therefore, their performance, especially when there are disk failure(s), is of interest. In the first part of the dissertation, the operations for the RAID5, RAID6, EVENODD and RM2 schemes are described. A cost model is developed for these RAID schemes by analyzing the operations in various operating modes. This cost model offers a measure of the volume of data being transmitted, and provides adevice-independent comparison of the efficiency of these RAID schemes. Based on this cost model, the maximum throughput of a RAID scheme can be obtained given detailed disk characteristic and RAID configuration. Utilizing M/G/1 queuing model and other favorable modeling assumptions, a queuing analysis to obtain the mean read response time is described. Simulation is used to validate analytic results, as well as to evaluate the RAID systems in analytically intractable cases. The second part of this dissertation describes a new disk array architecture, namely Heterogeneous Disk Array (HDA). The HDA is motivated by a few observations of the trends in storage technology. The HDA architecture allows a disk array to have two forms of heterogeneity: (1) device heterogeneity, i.e., disks of different types can be incorporated in a single HDA; and (2) RAID level heterogeneity, i.e., various RAID schemes can coexist in the same array. The goal of this architecture is (1) utilizing the extra resource (i.e. bandwidth and capacity) introduced by new disk drives in an automated and efficient way; and (2) using appropriate RAID levels to meet the varying availability requirements for different applications. In HDA, each new object is associated with an appropriate RAID level and the allocation is carried out in a way to keep disk bandwidth and capacity utilizations balanced. Design considerations for the data structures of HDA metadata are described, followed by the actual design of the data structures and flowcharts for the most frequent operations. Then a data allocation algorithm is described in detail. Finally, the HDA architecture is prototyped based on the DASim simulation toolkit developed at NJIT and simulation results of an HDA with two RAID levels (RAID 1 and RAIDS) are presented