Investigation of Sparsifying Transforms in Compressed Sensing for Magnetic Resonance Imaging with Fasttestcs

The goal of this contribution is to achieve higher reduction factors for faster Magnetic Resonance Imaging (MRI) scans with better Image Quality (IQ) by using Compressed Sensing (CS). This can be accomplished by adopting and understanding better sparsifying transforms for CS in MRI. There is a tremendous number of transforms and optional settings potentially available. Additionally, the amount of research in CS is growing, with possible duplication and difficult practical evaluation and comparison. However, no in-depth analysis of the effectiveness of different redundant sparsifying transforms on MRI images with CS has been undertaken until this work. New theoretical sparsity bounds for the dictionary restricted isometry property constants in CS are presented with mathematical proof. In order to verify the sparsifying transforms in this setting, the experiments focus on several redundant transforms contrasting them with orthogonal transforms. The transforms investigated are Wavelet (WT), Cosine (CT), contourlet, curvelet, k-means singular value decomposition, and Gabor. Several variations of these transforms with corresponding filter options are developed and tested in compression and CS simulations. Translation Invariance (TI) in transforms is found to be a key contributing factor in producing good IQ because any particular translation of the signal will not effect the transform representation. Some transforms tested here are TI and many others are made TI by transforming small overlapping image patches. These transforms are tested by comparing different under-sampling patterns and reduction ratios with varying image types including MRI data. Radial, spiral, and various random patterns are implemented and demonstrate that the TIWT is very robust across all under-sampling patterns. Results of the TIWT simulations show improvements in de-noising and artifact suppression over that of individual orthogonal wavelets and total variation ell-1 minimization in CS simulations. Some of these transforms add considerable time to the CS simulations and prohibit extensive testing of large 3D MRI datasets. Therefore, the FastTestCS software simulation framework is developed and customized for testing images, under-samping patterns and sparsifying transforms. This novel software is offered as a practical, robust, universal framework for evaluating and developing simulations in order to quickly test sparsifying transforms for CS MRI

On the Effectiveness of Leukocytes Classification Methods in a Real Application Scenario

Automating the analysis of digital microscopic images to identify the cell sub-types or the presence of illness has assumed a great importance since it aids the laborious manual process of review and diagnosis. In this paper, we have focused on the analysis of white blood cells. They are the body’s main defence against infections and diseases and, therefore, their reliable classification is very important. Current systems for leukocyte analysis are mainly dedicated to: counting, sub-types classification, disease detection or classification. Although these tasks seem very different, they share many steps in the analysis process, especially those dedicated to the detection of cells in blood smears. A very accurate detection step gives accurate results in the classification of white blood cells. Conversely, when detection is not accurate, it can adversely affect classification performance. However, it is very common in real-world applications that work on inaccurate or non-accurate regions. Many problems can affect detection results. They can be related to the quality of the blood smear images, e.g., colour and lighting conditions, absence of standards, or even density and presence of overlapping cells. To this end, we performed an in-depth investigation of the above scenario, simulating the regions produced by detection-based systems. We exploit various image descriptors combined with different classifiers, including CNNs, in order to evaluate which is the most suitable in such a scenario, when performing two different tasks: Classification of WBC subtypes and Leukaemia detection. Experimental results have shown that Convolutional Neural Networks are very robust in such a scenario, outperforming common machine learning techniques combined with hand-crafted descriptors. However, when exploiting appropriate images for model training, even simpler approaches can lead to accurate results in both tasks

NASA Tech Briefs, June 2001

Topics covered include: Sensors; Electronic Components and Systems; Software Engineering; Materials; Manufacturing/Fabrication; physical Sciences; Information Sciences

Biometrics

Biometrics uses methods for unique recognition of humans based upon one or more intrinsic physical or behavioral traits. In computer science, particularly, biometrics is used as a form of identity access management and access control. It is also used to identify individuals in groups that are under surveillance. The book consists of 13 chapters, each focusing on a certain aspect of the problem. The book chapters are divided into three sections: physical biometrics, behavioral biometrics and medical biometrics. The key objective of the book is to provide comprehensive reference and text on human authentication and people identity verification from both physiological, behavioural and other points of view. It aims to publish new insights into current innovations in computer systems and technology for biometrics development and its applications. The book was reviewed by the editor Dr. Jucheng Yang, and many of the guest editors, such as Dr. Girija Chetty, Dr. Norman Poh, Dr. Loris Nanni, Dr. Jianjiang Feng, Dr. Dongsun Park, Dr. Sook Yoon and so on, who also made a significant contribution to the book

Advancements and Breakthroughs in Ultrasound Imaging

Ultrasonic imaging is a powerful diagnostic tool available to medical practitioners, engineers and researchers today. Due to the relative safety, and the non-invasive nature, ultrasonic imaging has become one of the most rapidly advancing technologies. These rapid advances are directly related to the parallel advancements in electronics, computing, and transducer technology together with sophisticated signal processing techniques. This book focuses on state of the art developments in ultrasonic imaging applications and underlying technologies presented by leading practitioners and researchers from many parts of the world

Recent Advances in Signal Processing

The signal processing task is a very critical issue in the majority of new technological inventions and challenges in a variety of applications in both science and engineering fields. Classical signal processing techniques have largely worked with mathematical models that are linear, local, stationary, and Gaussian. They have always favored closed-form tractability over real-world accuracy. These constraints were imposed by the lack of powerful computing tools. During the last few decades, signal processing theories, developments, and applications have matured rapidly and now include tools from many areas of mathematics, computer science, physics, and engineering. This book is targeted primarily toward both students and researchers who want to be exposed to a wide variety of signal processing techniques and algorithms. It includes 27 chapters that can be categorized into five different areas depending on the application at hand. These five categories are ordered to address image processing, speech processing, communication systems, time-series analysis, and educational packages respectively. The book has the advantage of providing a collection of applications that are completely independent and self-contained; thus, the interested reader can choose any chapter and skip to another without losing continuity

Implementation and validation of radiomics in lung cancer

Masteroppgave i fysikkPHYS399MAMN-PHY

Modeling and rendering for development of a virtual bone surgery system

A virtual bone surgery system is developed to provide the potential of a realistic, safe, and controllable environment for surgical education. It can be used for training in orthopedic surgery, as well as for planning and rehearsal of bone surgery procedures...Using the developed system, the user can perform virtual bone surgery by simultaneously seeing bone material removal through a graphic display device, feeling the force via a haptic deice, and hearing the sound of tool-bone interaction --Abstract, page iii

High-performance hardware accelerators for image processing in space applications

Mars is a hard place to reach. While there have been many notable success stories in getting probes to the Red Planet, the historical record is full of bad news. The success rate for actually landing on the Martian surface is even worse, roughly 30%. This low success rate must be mainly credited to the Mars environment characteristics. In the Mars atmosphere strong winds frequently breath. This phenomena usually modifies the lander descending trajectory diverging it from the target one. Moreover, the Mars surface is not the best place where performing a safe land. It is pitched by many and close craters and huge stones, and characterized by huge mountains and hills (e.g., Olympus Mons is 648 km in diameter and 27 km tall). For these reasons a mission failure due to a landing in huge craters, on big stones or on part of the surface characterized by a high slope is highly probable. In the last years, all space agencies have increased their research efforts in order to enhance the success rate of Mars missions. In particular, the two hottest research topics are: the active debris removal and the guided landing on Mars. The former aims at finding new methods to remove space debris exploiting unmanned spacecrafts. These must be able to autonomously: detect a debris, analyses it, in order to extract its characteristics in terms of weight, speed and dimension, and, eventually, rendezvous with it. In order to perform these tasks, the spacecraft must have high vision capabilities. In other words, it must be able to take pictures and process them with very complex image processing algorithms in order to detect, track and analyse the debris. The latter aims at increasing the landing point precision (i.e., landing ellipse) on Mars. Future space-missions will increasingly adopt Video Based Navigation systems to assist the entry, descent and landing (EDL) phase of space modules (e.g., spacecrafts), enhancing the precision of automatic EDL navigation systems. For instance, recent space exploration missions, e.g., Spirity, Oppurtunity, and Curiosity, made use of an EDL procedure aiming at following a fixed and precomputed descending trajectory to reach a precise landing point. This approach guarantees a maximum landing point precision of 20 km. By comparing this data with the Mars environment characteristics, it is possible to understand how the mission failure probability still remains really high. A very challenging problem is to design an autonomous-guided EDL system able to even more reduce the landing ellipse, guaranteeing to avoid the landing in dangerous area of Mars surface (e.g., huge craters or big stones) that could lead to the mission failure. The autonomous behaviour of the system is mandatory since a manual driven approach is not feasible due to the distance between Earth and Mars. Since this distance varies from 56 to 100 million of km approximately due to the orbit eccentricity, even if a signal transmission at the light speed could be possible, in the best case the transmission time would be around 31 minutes, exceeding so the overall duration of the EDL phase. In both applications, algorithms must guarantee self-adaptability to the environmental conditions. Since the Mars (and in general the space) harsh conditions are difficult to be predicted at design time, these algorithms must be able to automatically tune the internal parameters depending on the current conditions. Moreover, real-time performances are another key factor. Since a software implementation of these computational intensive tasks cannot reach the required performances, these algorithms must be accelerated via hardware. For this reasons, this thesis presents my research work done on advanced image processing algorithms for space applications and the associated hardware accelerators. My research activity has been focused on both the algorithm and their hardware implementations. Concerning the first aspect, I mainly focused my research effort to integrate self-adaptability features in the existing algorithms. While concerning the second, I studied and validated a methodology to efficiently develop, verify and validate hardware components aimed at accelerating video-based applications. This approach allowed me to develop and test high performance hardware accelerators that strongly overcome the performances of the actual state-of-the-art implementations. The thesis is organized in four main chapters. Chapter 2 starts with a brief introduction about the story of digital image processing. The main content of this chapter is the description of space missions in which digital image processing has a key role. A major effort has been spent on the missions in which my research activity has a substantial impact. In particular, for these missions, this chapter deeply analizes and evaluates the state-of-the-art approaches and algorithms. Chapter 3 analyzes and compares the two technologies used to implement high performances hardware accelerators, i.e., Application Specific Integrated Circuits (ASICs) and Field Programmable Gate Arrays (FPGAs). Thanks to this information the reader may understand the main reasons behind the decision of space agencies to exploit FPGAs instead of ASICs for high-performance hardware accelerators in space missions, even if FPGAs are more sensible to Single Event Upsets (i.e., transient error induced on hardware component by alpha particles and solar radiation in space). Moreover, this chapter deeply describes the three available space-grade FPGA technologies (i.e., One-time Programmable, Flash-based, and SRAM-based), and the main fault-mitigation techniques against SEUs that are mandatory for employing space-grade FPGAs in actual missions. Chapter 4 describes one of the main contribution of my research work: a library of high-performance hardware accelerators for image processing in space applications. The basic idea behind this library is to offer to designers a set of validated hardware components able to strongly speed up the basic image processing operations commonly used in an image processing chain. In other words, these components can be directly used as elementary building blocks to easily create a complex image processing system, without wasting time in the debug and validation phase. This library groups the proposed hardware accelerators in IP-core families. The components contained in a same family share the same provided functionality and input/output interface. This harmonization in the I/O interface enables to substitute, inside a complex image processing system, components of the same family without requiring modifications to the system communication infrastructure. In addition to the analysis of the internal architecture of the proposed components, another important aspect of this chapter is the methodology used to develop, verify and validate the proposed high performance image processing hardware accelerators. This methodology involves the usage of different programming and hardware description languages in order to support the designer from the algorithm modelling up to the hardware implementation and validation. Chapter 5 presents the proposed complex image processing systems. In particular, it exploits a set of actual case studies, associated with the most recent space agency needs, to show how the hardware accelerator components can be assembled to build a complex image processing system. In addition to the hardware accelerators contained in the library, the described complex system embeds innovative ad-hoc hardware components and software routines able to provide high performance and self-adaptable image processing functionalities. To prove the benefits of the proposed methodology, each case study is concluded with a comparison with the current state-of-the-art implementations, highlighting the benefits in terms of performances and self-adaptability to the environmental conditions