Finding co-solvers on Twitter, with a little help from Linked Data

In this paper we propose a method for suggesting potential collaborators for solving innovation challenges online, based on their competence, similarity of interests and social proximity with the user. We rely on Linked Data to derive a measure of semantic relatedness that we use to enrich both user profiles and innovation problems with additional relevant topics, thereby improving the performance of co-solver recommendation. We evaluate this approach against state of the art methods for query enrichment based on the distribution of topics in user profiles, and demonstrate its usefulness in recommending collaborators that are both complementary in competence and compatible with the user. Our experiments are grounded using data from the social networking service Twitter.com

Semantic data mining and linked data for a recommender system in the AEC industry

Even though it can provide design teams with valuable performance insights and enhance decision-making, monitored building data is rarely reused in an effective feedback loop from operation to design. Data mining allows users to obtain such insights from the large datasets generated throughout the building life cycle. Furthermore, semantic web technologies allow to formally represent the built environment and retrieve knowledge in response to domain-specific requirements. Both approaches have independently established themselves as powerful aids in decision-making. Combining them can enrich data mining processes with domain knowledge and facilitate knowledge discovery, representation and reuse. In this article, we look into the available data mining techniques and investigate to what extent they can be fused with semantic web technologies to provide recommendations to the end user in performance-oriented design. We demonstrate an initial implementation of a linked data-based system for generation of recommendations

Collaborative recommendations with content-based filters for cultural activities via a scalable event distribution platform

Nowadays, most people have limited leisure time and the offer of (cultural) activities to spend this time is enormous. Consequently, picking the most appropriate events becomes increasingly difficult for end-users. This complexity of choice reinforces the necessity of filtering systems that assist users in finding and selecting relevant events. Whereas traditional filtering tools enable e.g. the use of keyword-based or filtered searches, innovative recommender systems draw on user ratings, preferences, and metadata describing the events. Existing collaborative recommendation techniques, developed for suggesting web-shop products or audio-visual content, have difficulties with sparse rating data and can not cope at all with event-specific restrictions like availability, time, and location. Moreover, aggregating, enriching, and distributing these events are additional requisites for an optimal communication channel. In this paper, we propose a highly-scalable event recommendation platform which considers event-specific characteristics. Personal suggestions are generated by an advanced collaborative filtering algorithm, which is more robust on sparse data by extending user profiles with presumable future consumptions. The events, which are described using an RDF/OWL representation of the EventsML-G2 standard, are categorized and enriched via smart indexing and open linked data sets. This metadata model enables additional content-based filters, which consider event-specific characteristics, on the recommendation list. The integration of these different functionalities is realized by a scalable and extendable bus architecture. Finally, focus group conversations were organized with external experts, cultural mediators, and potential end-users to evaluate the event distribution platform and investigate the possible added value of recommendations for cultural participation

Computerized crime linkage systems: A critical review and research agenda

Computerized crime linkage systems are meant to assist the police in determining whether crimes have been committed by the same offender. In this article, the authors assess these systems critically and identify four assumptions that affect the effectiveness of these systems. These assumptions are that (a) data in the systems can be coded reliably, (b) data in the systems are accurate, (c) violent serial offenders exhibit consistent but distinctive patterns of behavior, and (d) analysts have the ability to use the data in the systems to link crimes accurately. The authors argue that there is no compelling empirical support for any of the four assumptions, and they outline a research agenda for testing each assumption. Until evidence supporting these assumptions becomes available, the value of linkage systems will remain open to debate

Hybrid Profiling in Information Retrieval

Abstract-One of the main challenges in search engine quality of service is how to satisfy the needs and the interests of individual users. This raises the fundamental issue of how to identify and select the information that is relevant to a specific user. This concern over generic provision and the lack of search precision have provided the impetus for the research into Web Search personalisation. In this paper a hybrid user profiling system is proposed -a combination of explicit and implicit user profiles for improving the web search effectiveness in terms of precision and recall. The proposed system is content-based and implements the Vector Space Model. Experimental results, supported by significance tests, indicate that the system offers better precision and recall in comparison to traditional search engines

A multilayer network approach for guiding drug repositioning in neglected diseases

Drug development for neglected diseases has been historically hampered due to lack of market incentives. The advent of public domain resources containing chemical information from high throughput screenings is changing the landscape of drug discovery for these diseases. In this work we took advantage of data from extensively studied organisms like human, mouse, E. coli and yeast, among others, to develop a novel integrative network model to prioritize and identify candidate drug targets in neglected pathogen proteomes, and bioactive drug-like molecules. We modeled genomic (proteins) and chemical (bioactive compounds) data as a multilayer weighted network graph that takes advantage of bioactivity data across 221 species, chemical similarities between 1.7 105 compounds and several functional relations among 1.67 105 proteins. These relations comprised orthology, sharing of protein domains, and shared participation in defined biochemical pathways. We showcase the application of this network graph to the problem of prioritization of new candidate targets, based on the information available in the graph for known compound-target associations. We validated this strategy by performing a cross validation procedure for known mouse and Trypanosoma cruzi targets and showed that our approach outperforms classic alignment-based approaches. Moreover, our model provides additional flexibility as two different network definitions could be considered, finding in both cases qualitatively different but sensible candidate targets. We also showcase the application of the network to suggest targets for orphan compounds that are active against Plasmodium falciparum in high-throughput screens. In this case our approach provided a reduced prioritization list of target proteins for the query molecules and showed the ability to propose new testable hypotheses for each compound. Moreover, we found that some predictions highlighted by our network model were supported by independent experimental validations as found post-facto in the literature.Fil: Berenstein, Ariel José. Fundación Instituto Leloir; Argentina. Universidad de Buenos Aires. Facultad de Ingeniería. Departamento de Física; ArgentinaFil: Magariños, María Paula. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Biotecnológicas. Instituto de Investigaciones Biotecnológicas "Dr. Raúl Alfonsín" (sede Chascomús). Universidad Nacional de San Martín. Instituto de Investigaciones Biotecnológicas. Instituto de Investigaciones Biotecnológicas "Dr. Raúl Alfonsín" (sede Chascomús); ArgentinaFil: Chernomoretz, Ariel. Fundación Instituto Leloir; Argentina. Universidad de Buenos Aires. Facultad de Ingeniería. Departamento de Física; ArgentinaFil: Fernandez Aguero, Maria Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Biotecnológicas. Instituto de Investigaciones Biotecnológicas "Dr. Raúl Alfonsín" (sede Chascomús). Universidad Nacional de San Martín. Instituto de Investigaciones Biotecnológicas. Instituto de Investigaciones Biotecnológicas "Dr. Raúl Alfonsín" (sede Chascomús); Argentin

Integration and mining of malaria molecular, functional and pharmacological data: how far are we from a chemogenomic knowledge space?

The organization and mining of malaria genomic and post-genomic data is highly motivated by the necessity to predict and characterize new biological targets and new drugs. Biological targets are sought in a biological space designed from the genomic data from Plasmodium falciparum, but using also the millions of genomic data from other species. Drug candidates are sought in a chemical space containing the millions of small molecules stored in public and private chemolibraries. Data management should therefore be as reliable and versatile as possible. In this context, we examined five aspects of the organization and mining of malaria genomic and post-genomic data: 1) the comparison of protein sequences including compositionally atypical malaria sequences, 2) the high throughput reconstruction of molecular phylogenies, 3) the representation of biological processes particularly metabolic pathways, 4) the versatile methods to integrate genomic data, biological representations and functional profiling obtained from X-omic experiments after drug treatments and 5) the determination and prediction of protein structures and their molecular docking with drug candidate structures. Progresses toward a grid-enabled chemogenomic knowledge space are discussed.Comment: 43 pages, 4 figures, to appear in Malaria Journa

Ontology-Based Recommendation of Editorial Products

Major academic publishers need to be able to analyse their vast catalogue of products and select the best items to be marketed in scientific venues. This is a complex exercise that requires characterising with a high precision the topics of thousands of books and matching them with the interests of the relevant communities. In Springer Nature, this task has been traditionally handled manually by publishing editors. However, the rapid growth in the number of scientific publications and the dynamic nature of the Computer Science landscape has made this solution increasingly inefficient. We have addressed this issue by creating Smart Book Recommender (SBR), an ontology-based recommender system developed by The Open University (OU) in collaboration with Springer Nature, which supports their Computer Science editorial team in selecting the products to market at specific venues. SBR recommends books, journals, and conference proceedings relevant to a conference by taking advantage of a semantically enhanced representation of about 27K editorial products. This is based on the Computer Science Ontology, a very large-scale, automatically generated taxonomy of research areas. SBR also allows users to investigate why a certain publication was suggested by the system. It does so by means of an interactive graph view that displays the topic taxonomy of the recommended editorial product and compares it with the topic-centric characterization of the input conference. An evaluation carried out with seven Springer Nature editors and seven OU researchers has confirmed the effectiveness of the solution