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Supervised Classification: Quite a Brief Overview
The original problem of supervised classification considers the task of
automatically assigning objects to their respective classes on the basis of
numerical measurements derived from these objects. Classifiers are the tools
that implement the actual functional mapping from these measurements---also
called features or inputs---to the so-called class label---or output. The
fields of pattern recognition and machine learning study ways of constructing
such classifiers. The main idea behind supervised methods is that of learning
from examples: given a number of example input-output relations, to what extent
can the general mapping be learned that takes any new and unseen feature vector
to its correct class? This chapter provides a basic introduction to the
underlying ideas of how to come to a supervised classification problem. In
addition, it provides an overview of some specific classification techniques,
delves into the issues of object representation and classifier evaluation, and
(very) briefly covers some variations on the basic supervised classification
task that may also be of interest to the practitioner
Innate immunity and neuroinflammation
Copyright © 2013 Abhishek Shastri et al. This is an open access article distributed under the Creative Commons Attribution
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Inflammation of central nervous system (CNS) is usually associated with trauma and infection. Neuroinflammation occurs in close relation to trauma, infection, and neurodegenerative diseases. Low-level neuroinflammation is considered to have beneficial effects whereas chronic neuroinflammation can be harmful. Innate immune system consisting of pattern-recognition receptors, macrophages, and complement system plays a key role in CNS homeostasis following injury and infection. Here, we discuss how innate immune components can also contribute to neuroinflammation and neurodegeneration
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