Multimodal information spaces for content-based image retrieval

Abstract. Image collections today are increasingly larger in size, and they continue to grow constantly. Without the help of image search systems these abundant visual records collected in many different fields and domains may remain unused and inaccessible. Many available image databases often contain complementary modalities, such as attached text resources, which can be used to build an index for querying with keywords. However, sometimes users do not have or do not know the right words to express what they need, and, in addition, keywords do not express all the visual variations that an image may contain. Using example images as queries can be viewed as an alternative in different scenarios such as searching images using a mobile phone with a coupled camera, or supporting medical diagnosis by searching a large medical image collection. Still, matching only visual features between the query and image databases may lead to undesirable results from the user's perspective. These conditions make the process of finding relevant images for a specific information need very challenging, time consuming or even frustrating. Instead of considering only a single data modality to build image search indexes, the simultaneous use of both, visual and text data modalities, has been suggested. Non-visual information modalities may provide complementary information to enrich the image representation. The goal of this research work is to study the relationships between visual contents and text terms to build useful indexes for image search. A family of algorithms based on matrix factorization are proposed for extracting the multimodal aspects from an image collection. Using this knowledge about how visual features and text terms correlate, a search index is constructed, which can be searched using keywords, example images or combinations of both. Systematic experiments were conducted on different data sets to evaluate the proposed indexing algorithms. The experimental results showed that multimodal indexing is an effective strategy for designing image search systems.Las colecciones de imágenes hoy en día son muy grandes y crecen constantemente. Sin la ayuda de sistemas para la búsqueda de imágenes esos abundantes registros visuales que han sido recolectados en diferentes areas del conocimiento pueden permanecer aislados sin uso. Muchas bases de datos de imágenes contienen modalidades de datos complementarias, como los recursos textuales que pueden ser utilizados para crear índices de búsqueda. Sin embargo, algunas veces los usuarios no tienen o no saben qué palabras utilizar para encontrar lo que necesitan, y adicionalmente, las palabras clave no expresan todas las variaciones visuales que una imagen puede tener. Utilizar imágenes de ejemplo para expresar la consulta puede ser visto como una alternativa, por ejemplo buscar imágenes con teléfonos móviles, o dar soporte al diagnóstico médico con las imágenes de los pacientes. Aún así, emparejar correctamente las características visuales de la consulta y las imágenes en la base de datos puede llevar a resultados semánticamente incorrectos. Estas condiciones hacen que el proceso de buscar imágenes relevantes para una necesidad de información particular sea una tarea difícil, que consume mucho tiempo o que incluso puede ser frustrante. En lugar de considerar solo una modalidad de datos para construir índices de búsqueda para imágenes, el uso simultáneo de las modalidades visual y textual ha sido sugerido. Las modalidades no visuales pueden proporcionar información complementaria para enriquecer la representación de las imágenes. El objetivo de este trabajo de investigación es estudiar las relaciones entre los contenidos visuales y los términos textuales, para construir índices de búsqueda útiles. Este trabajo propone una familia de algoritmos basados en factorización de matrices para extraer los aspectos multimodales de una colección de imágenes. Utilizando este conocimiento acerca de cómo las características visuales se correlacionan con los términos textuales, se construye un índice que puede ser consultado con palabras clave, imágenes de ejemplo o por combinaciones de estas dos. Se realizaron experimentos sistemáticos en diferentes conjuntos de datos para evaluar los algoritmos de indexamiento propuestos. Los resultados muestran que el indexamiento multimodal es una estrategia efectiva para diseñar sistemas de búsqueda de imágenes.Doctorad

Image similarity in medical images

Recent experiments have indicated a strong influence of the substrate grain orientation on the self-ordering in anodic porous alumina. Anodic porous alumina with straight pore channels grown in a stable, self-ordered manner is formed on (001) oriented Al grain, while disordered porous pattern is formed on (101) oriented Al grain with tilted pore channels growing in an unstable manner. In this work, numerical simulation of the pore growth process is carried out to understand this phenomenon. The rate-determining step of the oxide growth is assumed to be the Cabrera-Mott barrier at the oxide/electrolyte (o/e) interface, while the substrate is assumed to determine the ratio β between the ionization and oxidation reactions at the metal/oxide (m/o) interface. By numerically solving the electric field inside a growing porous alumina during anodization, the migration rates of the ions and hence the evolution of the o/e and m/o interfaces are computed. The simulated results show that pore growth is more stable when β is higher. A higher β corresponds to more Al ionized and migrating away from the m/o interface rather than being oxidized, and hence a higher retained O:Al ratio in the oxide. Experimentally measured oxygen content in the self-ordered porous alumina on (001) Al is indeed found to be about 3% higher than that in the disordered alumina on (101) Al, in agreement with the theoretical prediction. The results, therefore, suggest that ionization on (001) Al substrate is relatively easier than on (101) Al, and this leads to the more stable growth of the pore channels on (001) Al

Effective Features and Machine Learning Methods for Document Classification

Document classification has been involved in a variety of applications, such as phishing and fraud detection, news categorisation, and information retrieval. This thesis aims to provide novel solutions to several important problems presented by document classification. First, an improved Principal Components Analysis (PCA), based on similarity and correlation criteria instead of covariance, is proposed, which aims to capture low-dimensional feature subset that facilitates improved performance in text classification. The experimental results have demonstrated the advantages and usefulness of the proposed method for text classification in high-dimensional feature space in terms of the number of features required to achieve the best classification accuracy. Second, two hybrid feature-subset selection methods are proposed based on the combination (via either union or intersection) of the results of both supervised (in one method) and unsupervised (in the other method) filter approaches prior to the use of a wrapper, leading to low-dimensional feature subset that can achieve both high classification accuracy and good interpretability, and spend less processing time than most current methods. The experimental results have demonstrated the effectiveness of the proposed methods for feature subset selection in high-dimensional feature space in terms of the number of selected features and the processing time spent to achieve the best classification accuracy. Third, a class-specific (supervised) pre-trained approach based on a sparse autoencoder is proposed for acquiring low-dimensional interesting structure of relevant features, which can be used for high-performance document classification. The experimental results have demonstrated the merit of this proposed method for document classification in high-dimensional feature space, in terms of the limited number of features required to achieve good classification accuracy. Finally, deep classifier structures associated with a stacked autoencoder (SAE) for higher-level feature extraction are investigated, aiming to overcome the difficulties experienced in training deep neural networks with limited training data in high-dimensional feature space, such as overfitting and vanishing/exploding gradients. This investigation has resulted in a three-stage learning algorithm for training deep neural networks. In comparison with support vector machines (SVMs) combined with SAE and Deep Multilayer Perceptron (DMLP) with random weight initialisation, the experimental results have shown the advantages and effectiveness of the proposed three-stage learning algorithm

Use Case Oriented Medical Visual Information Retrieval & System Evaluation

Large amounts of medical visual data are produced daily in hospitals, while new imaging techniques continue to emerge. In addition, many images are made available continuously via publications in the scientific literature and can also be valuable for clinical routine, research and education. Information retrieval systems are useful tools to provide access to the biomedical literature and fulfil the information needs of medical professionals. The tools developed in this thesis can potentially help clinicians make decisions about difficult diagnoses via a case-based retrieval system based on a use case associated with a specific evaluation task. This system retrieves articles from the biomedical literature when querying with a case description and attached images. This thesis proposes a multimodal approach for medical case-based retrieval with focus on the integration of visual information connected to text. Furthermore, the ImageCLEFmed evaluation campaign was organised during this thesis promoting medical retrieval system evaluation

Added benefits of computer-assisted analysis of Hematoxylin-Eosin stained breast histopathological digital slides

This thesis aims at determining if computer-assisted analysis can be used to better understand pathologists’ perception of mitotic figures on Hematoxylin-Eosin (HE) stained breast histopathological digital slides. It also explores the feasibility of reproducible histologic nuclear atypia scoring by incorporating computer-assisted analysis to cytological scores given by a pathologist. In addition, this thesis investigates the possibility of computer-assisted diagnosis for categorizing HE breast images into different subtypes of cancer or benign masses. In the first study, a data set of 453 mitoses and 265 miscounted non-mitoses within breast cancer digital slides were considered. Different features were extracted from the objects in different channels of eight colour spaces. The findings from the first research study suggested that computer-aided image analysis can provide a better understanding of image-related features related to discrepancies among pathologists in recognition of mitoses. Two tasks done routinely by the pathologists are making diagnosis and grading the breast cancer. In the second study, a new tool for reproducible nuclear atypia scoring in breast cancer histological images was proposed. The third study proposed and tested MuDeRN (MUlti-category classification of breast histopathological image using DEep Residual Networks), which is a framework for classifying hematoxylin-eosin stained breast digital slides either as benign or cancer, and then categorizing cancer and benign cases into four different subtypes each. The studies indicated that computer-assisted analysis can aid in both nuclear grading (COMPASS) and breast cancer diagnosis (MuDeRN). The results could be used to improve current status of breast cancer prognosis estimation through reducing the inter-pathologist disagreement in counting mitotic figures and reproducible nuclear grading. It can also improve providing a second opinion to the pathologist for making a diagnosis