Auditory Streaming: Behavior, Physiology, and Modeling

Auditory streaming is a fundamental aspect of auditory perception. It refers to the ability to parse mixed acoustic events into meaningful streams where each stream is assumed to originate from a separate source. Despite wide interest and increasing scientific investigations over the last decade, the neural mechanisms underlying streaming still remain largely unknown. A simple example of this mystery concerns the streaming of simple tone sequences, and the general assumption that separation along the tonotopic axis is sufficient for stream segregation. However, this dissertation research casts doubt on the validity of this assumption. First, behavioral measures of auditory streaming in ferrets prove that they can be used as an animal model to study auditory streaming. Second, responses from neurons in the primary auditory cortex (A1) of ferrets show that spectral components that are well-separated in frequency produce comparably segregated responses along the tonotopic axis, no matter whether presented synchronously or consecutively, despite the substantial differences in their streaming percepts when measured psychoacoustically in humans. These results argue against the notion that tonotopic separation per se is a sufficient neural correlate of stream segregation. Thirdly, comparing responses during behavior to those during the passive condition, the temporal correlations of spiking activity between neurons belonging to the same stream display an increased correlation, while responses among neurons belonging to different streams become less correlated. Rapid task-related plasticity of neural receptive fields shows a pattern that is consistent with the changes in correlation. Taken together these results indicate that temporal coherence is a plausible neural correlate of auditory streaming. Finally, inspired by the above biological findings, we propose a computational model of auditory scene analysis, which uses temporal coherence as the primary criterion for predicting stream formation. The promising results of this dissertation research significantly advance our understanding of auditory streaming and perception

Biophysical modeling of a cochlear implant system: progress on closed-loop design using a novel patient-specific evaluation platform

The modern cochlear implant is one of the most successful neural stimulation devices, which partially mimics the workings of the auditory periphery. In the last few decades it has created a paradigm shift in hearing restoration of the deaf population, which has led to more than 324,000 cochlear implant users today. Despite its great success there is great disparity in patient outcomes without clear understanding of the aetiology of this variance in implant performance. Furthermore speech recognition in adverse conditions or music appreciation is still not attainable with today's commercial technology. This motivates the research for the next generation of cochlear implants that takes advantage of recent developments in electronics, neuroscience, nanotechnology, micro-mechanics, polymer chemistry and molecular biology to deliver high fidelity sound. The main difficulties in determining the root of the problem in the cases where the cochlear implant does not perform well are two fold: first there is not a clear paradigm on how the electrical stimulation is perceived as sound by the brain, and second there is limited understanding on the plasticity effects, or learning, of the brain in response to electrical stimulation. These significant knowledge limitations impede the design of novel cochlear implant technologies, as the technical specifications that can lead to better performing implants remain undefined. The motivation of the work presented in this thesis is to compare and contrast the cochlear implant neural stimulation with the operation of the physiological healthy auditory periphery up to the level of the auditory nerve. As such design of novel cochlear implant systems can become feasible by gaining insight on the question `how well does a specific cochlear implant system approximate the healthy auditory periphery?' circumventing the necessity of complete understanding of the brain's comprehension of patterned electrical stimulation delivered from a generic cochlear implant device. A computational model, termed Digital Cochlea Stimulation and Evaluation Tool (‘DiCoStET’) has been developed to provide an objective estimate of cochlear implant performance based on neuronal activation measures, such as vector strength and average activation. A patient-specific cochlea 3D geometry is generated using a model derived by a single anatomical measurement from a patient, using non-invasive high resolution computed tomography (HRCT), and anatomically invariant human metrics and relations. Human measurements of the neuron route within the inner ear enable an innervation pattern to be modelled which joins the space from the organ of Corti to the spiral ganglion subsequently descending into the auditory nerve bundle. An electrode is inserted in the cochlea at a depth that is determined by the user of the tool. The geometric relation between the stimulation sites on the electrode and the spiral ganglion are used to estimate an activating function that will be unique for the specific patient's cochlear shape and electrode placement. This `transfer function', so to speak, between electrode and spiral ganglion serves as a `digital patient' for validating novel cochlear implant systems. The novel computational tool is intended for use by bioengineers, surgeons, audiologists and neuroscientists alike. In addition to ‘DiCoStET’ a second computational model is presented in this thesis aiming at enhancing the understanding of the physiological mechanisms of hearing, specifically the workings of the auditory synapse. The purpose of this model is to provide insight on the sound encoding mechanisms of the synapse. A hypothetical mechanism is suggested in the release of neurotransmitter vesicles that permits the auditory synapse to encode temporal patterns of sound separately from sound intensity. DiCoStET was used to examine the performance of two different types of filters used for spectral analysis in the cochlear implant system, the Gammatone type filter and the Butterworth type filter. The model outputs suggest that the Gammatone type filter performs better than the Butterworth type filter. Furthermore two stimulation strategies, the Continuous Interleaved Stimulation (CIS) and Asynchronous Interleaved Stimulation (AIS) have been compared. The estimated neuronal stimulation spatiotemporal patterns for each strategy suggest that the overall stimulation pattern is not greatly affected by the temporal sequence change. However the finer detail of neuronal activation is different between the two strategies, and when compared to healthy neuronal activation patterns the conjecture is made that the sequential stimulation of CIS hinders the transmission of sound fine structure information to the brain. The effect of the two models developed is the feasibility of collaborative work emanating from various disciplines; especially electrical engineering, auditory physiology and neuroscience for the development of novel cochlear implant systems. This is achieved by using the concept of a `digital patient' whose artificial neuronal activation is compared to a healthy scenario in a computationally efficient manner to allow practical simulation times.Open Acces

Ultra-Wideband Secure Communications and Direct RF Sampling Transceivers

Larger wireless device bandwidth results in new capabilities in terms of higher data rates and security. The 5G evolution is focus on exploiting larger bandwidths for higher though-puts. Interference and co-existence issues can also be addressed by the larger bandwidth in the 5G and 6G evolution. This dissertation introduces of a novel Ultra-wideband (UWB) Code Division Multiple Access (CDMA) technique to exploit the largest bandwidth available in the upcoming wireless connectivity scenarios. The dissertation addresses interference immunity, secure communication at the physical layer and longer distance communication due to increased receiver sensitivity. The dissertation presents the design, workflow, simulations, hardware prototypes and experimental measurements to demonstrate the benefits of wideband Code-Division-Multiple-Access. Specifically, a description of each of the hardware and software stages is presented along with simulations of different scenarios using a test-bench and open-field measurements. The measurements provided experimental validation carried out to demonstrate the interference mitigation capabilities. In addition, Direct RF sampling techniques are employed to handle the larger bandwidth and avoid analog components. Additionally, a transmit and receive chain is designed and implemented at 28 GHz to provide a proof-of-concept for future 5G applications. The proposed wideband transceiver is also used to demonstrate higher accuracy direction finding, as much as 10 times improvement

Adaptive OFDM Radar for Target Detection and Tracking

We develop algorithms to detect and track targets by employing a wideband orthogonal frequency division multiplexing: OFDM) radar signal. The frequency diversity of the OFDM signal improves the sensing performance since the scattering centers of a target resonate variably at different frequencies. In addition, being a wideband signal, OFDM improves the range resolution and provides spectral efficiency. We first design the spectrum of the OFDM signal to improve the radar\u27s wideband ambiguity function. Our designed waveform enhances the range resolution and motivates us to use adaptive OFDM waveform in specific problems, such as the detection and tracking of targets. We develop methods for detecting a moving target in the presence of multipath, which exist, for example, in urban environments. We exploit the multipath reflections by utilizing different Doppler shifts. We analytically evaluate the asymptotic performance of the detector and adaptively design the OFDM waveform, by maximizing the noncentrality-parameter expression, to further improve the detection performance. Next, we transform the detection problem into the task of a sparse-signal estimation by making use of the sparsity of multiple paths. We propose an efficient sparse-recovery algorithm by employing a collection of multiple small Dantzig selectors, and analytically compute the reconstruction performance in terms of the $ell_1$-constrained minimal singular value. We solve a constrained multi-objective optimization algorithm to design the OFDM waveform and infer that the resultant signal-energy distribution is in proportion to the distribution of the target energy across different subcarriers. Then, we develop tracking methods for both a single and multiple targets. We propose an tracking method for a low-grazing angle target by realistically modeling different physical and statistical effects, such as the meteorological conditions in the troposphere, curved surface of the earth, and roughness of the sea-surface. To further enhance the tracking performance, we integrate a maximum mutual information based waveform design technique into the tracker. To track multiple targets, we exploit the inherent sparsity on the delay-Doppler plane to develop an computationally efficient procedure. For computational efficiency, we use more prior information to dynamically partition a small portion of the delay-Doppler plane. We utilize the block-sparsity property to propose a block version of the CoSaMP algorithm in the tracking filter

Monitoring system for long-distance pipelines subject to destructive attack

In an era of terrorism, it is important to protect critical pipeline infrastructure, especially in countries where life is strongly dependent on water and the economy on oil and gas. Structural health monitoring (SHM) using acoustic waves is one of the common solutions. However, considerable prior work has shown that pipes are cylindrical acoustic waveguides that support many dispersive, lossy modes; only the torsional T(0, 1) mode has zero dispersion. Although suitable transducers have been developed, these typically excite several modes, and even if they do not, bends and supports induce mode conversion. Moreover, the high-power transducers that could in principle be used to overcome noise and attenuation in long distance pipes present an obvious safety hazard with volatile products, making it difficult to distinguish signals and extract pipeline status information. The problem worsens as the pipe diameter increases or as the frequency rises (due to the increasing number of modes), if the pipe is buried (due to rising attenuation), or if the pipe carries a flowing product (because of additional acoustic noise). Any system is therefore likely to be short-range. This research proposes the use of distributed active sensor network to monitor long-range pipelines, by verifying continuity and sensing small disturbances. A 4-element cuboid Electromagnetic Acoustic Transducer (EMAT) is used to excite the longitudinal L(0,1) mode. Although the EMAT also excites other slower modes, long distance propagation allows their effects to be separated. Correlation detection is exploited to enhance signal-to-noise ratio (SNR), and code division multiplexing access (CDMA) is used to distinguish between nodes in a multi-node system. An extensive numerical search for multiphase quasi-orthogonal codes for different user numbers is conducted. The results suggest that side lobes degrade performance even with the highest possible discrimination factor. Golay complementary pairs (which can eliminate the side lobes completely, albeit at the price of a considerable reduction in speed) are therefore investigated as an alternative. Pipeline systems are first reviewed. Acoustic wave propagation is described using standard theory and a freeware modeling package. EMAT modeling is carried out by numerical calculation of electromagnetic fields. Signal propagation is investigated theoretically using a full system simulator that allows frequency-domain description of transducers, dispersion, multi-mode propagation, mode conversion and multiple reflections. Known codes for multiplexing are constructed using standard algorithms, and novel codes are discovered by an efficient directed search. Propagation of these codes in a dispersive system is simulated. Experiments are carried out using small, unburied air-filled copper pipes in a frequency range where the number of modes is small, and the attenuation and noise are low. Excellent agreement is obtained between theory and experiment. The propagation of pulses and multiplexed codes over distances up to 200 m are successfully demonstrated, and status changes introduced by removable reflectors are detected.Open Acces

Low pressure pneumatic servomechanisms

Tests on a continuous action low pressure electro-pneumatic linear motion servomechanism are described. Data from individual tests on the components of this system, including the servo valve and the actuator, is used for analogue computer simulations. The simulations are shown to model the experimental system over a wide range of conditions. A simple linear equation is shown to model many aspects of the behaviour of the system. This equation is presented in a form which enables the importance of many system parameters to be easily assessed. An all pneumatic linear-motion servo using discrete fluidic components is described. This system uses pulse-width modulated signals to control on/off valves. Tests on components of the system, including beam deflection proportional amplifiers, Schmitt triggers, valves and a fluidic displacement sensor and also on the complete servo are described. Shortcomings in currently available components are shown to limit the performance of both systems, and modifications necessary to improve their closed loop behaviour are proposed

Compassion without compensation :the novelists and Baron Bramwell

PhD ThesisMy purpose in this thesis is to explore the work of Nineteenth Century Condition of England novelists and to identify how and to what extent they addressed issues of industrial safety and used their skills to identify problems. I looked at the developing law of negligence over the period 1830-1880 with particular reference to compensation for injured workpeople and to the role played by the common law judiciary. My researches revealed that one judge, Baron Bramwell, carried great influence but used the common law as a tool to prevent injured employees from recovering damages. I identified Charles Dickens, who was acquainted with Bramwell, as the novelist who had the skills and outlets to make the greatest impression in the fight for reform. I consider whether there was any common ground between Dickens and Bramwell and thus seek to use Literature as a comfortable adjunct to Legal History in telling the story of the law’s development over the period in the field of industrial safety and of the search for an humane compensation system

The 1991 International Aerospace and Ground Conference on Lightning and Static Electricity, volume 2

The proceedings of the conference are reported. The conference focussed on lightning protection, detection, and forecasting. The conference was divided into 26 sessions based on research in lightning, static electricity, modeling, and mapping. These sessions spanned the spectrum from basic science to engineering, concentrating on lightning prediction and detection and on safety for ground facilities, aircraft, and aerospace vehicles