Models and Analysis of Vocal Emissions for Biomedical Applications

The MAVEBA Workshop proceedings, held on a biannual basis, collect the scientific papers presented both as oral and poster contributions, during the conference. The main subjects are: development of theoretical and mechanical models as an aid to the study of main phonatory dysfunctions, as well as the biomedical engineering methods for the analysis of voice signals and images, as a support to clinical diagnosis and classification of vocal pathologies

Models and analysis of vocal emissions for biomedical applications: 5th International Workshop: December 13-15, 2007, Firenze, Italy

The MAVEBA Workshop proceedings, held on a biannual basis, collect the scientific papers presented both as oral and poster contributions, during the conference. The main subjects are: development of theoretical and mechanical models as an aid to the study of main phonatory dysfunctions, as well as the biomedical engineering methods for the analysis of voice signals and images, as a support to clinical diagnosis and classification of vocal pathologies. The Workshop has the sponsorship of: Ente Cassa Risparmio di Firenze, COST Action 2103, Biomedical Signal Processing and Control Journal (Elsevier Eds.), IEEE Biomedical Engineering Soc. Special Issues of International Journals have been, and will be, published, collecting selected papers from the conference

Cepstral peak prominence: a comprehensive analysis

An analytical study of cepstral peak prominence (CPP) is presented, intended to provide an insight into its meaning and relation with voice perturbation parameters. To carry out this analysis, a parametric approach is adopted in which voice production is modelled using the traditional source-filter model and the first cepstral peak is assumed to have Gaussian shape. It is concluded that the meaning of CPP is very similar to that of the first rahmonic and some insights are provided on its dependence with fundamental frequency and vocal tract resonances. It is further shown that CPP integrates measures of voice waveform and periodicity perturbations, be them either amplitude, frequency or noise

Models and Analysis of Vocal Emissions for Biomedical Applications

The MAVEBA Workshop proceedings, held on a biannual basis, collect the scientific papers presented both as oral and poster contributions, during the conference. The main subjects are: development of theoretical and mechanical models as an aid to the study of main phonatory dysfunctions, as well as the biomedical engineering methods for the analysis of voice signals and images, as a support to clinical diagnosis and classification of vocal pathologies

Models and analysis of vocal emissions for biomedical applications

This book of Proceedings collects the papers presented at the 4th International Workshop on Models and Analysis of Vocal Emissions for Biomedical Applications, MAVEBA 2005, held 29-31 October 2005, Firenze, Italy. The workshop is organised every two years, and aims to stimulate contacts between specialists active in research and industrial developments, in the area of voice analysis for biomedical applications. The scope of the Workshop includes all aspects of voice modelling and analysis, ranging from fundamental research to all kinds of biomedical applications and related established and advanced technologies

Artificial Intelligence Procedure for the Screening of Genetic Syndromes Based on Voice Characteristics

: Perceptual and statistical evidence has highlighted voice characteristics of individuals affected by genetic syndromes that differ from those of normophonic subjects. In this paper, we propose a procedure for systematically collecting such pathological voices and developing AI-based automated tools to support differential diagnosis. Guidelines on the most appropriate recording devices, vocal tasks, and acoustical parameters are provided to simplify, speed up, and make the whole procedure homogeneous and reproducible. The proposed procedure was applied to a group of 56 subjects affected by Costello syndrome (CS), Down syndrome (DS), Noonan syndrome (NS), and Smith-Magenis syndrome (SMS). The entire database was divided into three groups: pediatric subjects (PS; individuals < 12 years of age), female adults (FA), and male adults (MA). In line with the literature results, the Kruskal-Wallis test and post hoc analysis with Dunn-Bonferroni test revealed several significant differences in the acoustical features not only between healthy subjects and patients but also between syndromes within the PS, FA, and MA groups. Machine learning provided a k-nearest-neighbor classifier with 86% accuracy for the PS group, a support vector machine (SVM) model with 77% accuracy for the FA group, and an SVM model with 84% accuracy for the MA group. These preliminary results suggest that the proposed method based on acoustical analysis and AI could be useful for an effective, non-invasive automatic characterization of genetic syndromes. In addition, clinicians could benefit in the case of genetic syndromes that are extremely rare or present multiple variants and facial phenotypes

Acoustic measurement of overall voice quality in sustained vowels and continuous speech

Measurement of dysphonia severity involves auditory-perceptual evaluations and acoustic analyses of sound waves. Meta-analysis of proportional associations between these two methods showed that many popular perturbation metrics and noise-to-harmonics and others ratios do not yield reasonable results. However, this meta-analysis demonstrated that the validity of specific autocorrelation- and cepstrum-based measures was much more convincing, and appointed ‘smoothed cepstral peak prominence’ as the most promising metric of dysphonia severity. Original research confirmed this inferiority of perturbation measures and superiority of cepstral indices in dysphonia measurement of laryngeal-vocal and tracheoesophageal voice samples. However, to be truly representative for daily voice use patterns, measurement of overall voice quality is ideally founded on the analysis of sustained vowels ánd continuous speech. A customized method for including both sample types and calculating the multivariate Acoustic Voice Quality Index (i.e., AVQI), was constructed for this purpose. Original study of the AVQI revealed acceptable results in terms of initial concurrent validity, diagnostic precision, internal and external cross-validity and responsiveness to change. It thus was concluded that the AVQI can track changes in dysphonia severity across the voice therapy process. There are many freely and commercially available computer programs and systems for acoustic metrics of dysphonia severity. We investigated agreements and differences between two commonly available programs (i.e., Praat and Multi-Dimensional Voice Program) and systems. The results indicated that clinicians better not compare frequency perturbation data across systems and programs and amplitude perturbation data across systems. Finally, acoustic information can also be utilized as a biofeedback modality during voice exercises. Based on a systematic literature review, it was cautiously concluded that acoustic biofeedback can be a valuable tool in the treatment of phonatory disorders. When applied with caution, acoustic algorithms (particularly cepstrum-based measures and AVQI) have merited a special role in assessment and/or treatment of dysphonia severity

Multi-band dysperiodicity analyses of disordered connected speech

The objective is to analyse vocal dysperiodicities in connected speech produced by dysphonic speakers. The analysis involves a variogram-based method that enables tracking instantaneous vocal dysperiodicities. The dysperiodicity trace is summarized by means of the signal-to-dysperiodicity ratio, which has been shown to correlate strongly with the perceived degree of hoarseness of the speaker. Previously, this method has been evaluated on small corpora only. In this article, analyses have been carried out on two corpora comprising over 250 and 700 speakers. This has enabled carrying out multi-frequency band and multi-cue analyses without risking overfitting. The analysis results are compared to the cepstral peak prominence, which is a popular cue that indirectly summarizes vocal dysperiodicities frame-wise. A perceptual rating has been available for the first corpus whereas speakers in the second corpus have been categorized as normal or pathological only. For the first corpus, results show that the correlation with perceptual scores increases statistically significantly for multi-band analysis compared to conventional full-band analysis. Also, combining the cepstral peak prominence with the low-frequency band signal-to-dysperiodicity ratio statistically significantly increases their combined correlation with perceptual scores. The signal-to-dysperiodicity ratios of the two corpora have been separately submitted to principal component analysis. The results show that the first two principal components are interpretable in terms of the degree of dysphonia and the spectral slope, respectively. The clinical relevance of the principal components has been confirmed by linear discriminant analysis. © 2010 Elsevier B.V. All rights reserved.SCOPUS: ar.jinfo:eu-repo/semantics/publishe