Machine Learning and Integrative Analysis of Biomedical Big Data.

Recent developments in high-throughput technologies have accelerated the accumulation of massive amounts of omics data from multiple sources: genome, epigenome, transcriptome, proteome, metabolome, etc. Traditionally, data from each source (e.g., genome) is analyzed in isolation using statistical and machine learning (ML) methods. Integrative analysis of multi-omics and clinical data is key to new biomedical discoveries and advancements in precision medicine. However, data integration poses new computational challenges as well as exacerbates the ones associated with single-omics studies. Specialized computational approaches are required to effectively and efficiently perform integrative analysis of biomedical data acquired from diverse modalities. In this review, we discuss state-of-the-art ML-based approaches for tackling five specific computational challenges associated with integrative analysis: curse of dimensionality, data heterogeneity, missing data, class imbalance and scalability issues

Human Action Recognition and Monitoring in Ambient Assisted Living Environments

Population ageing is set to become one of the most significant challenges of the 21st century, with implications for almost all sectors of society. Especially in developed countries, governments should immediately implement policies and solutions to facilitate the needs of an increasingly older population. Ambient Intelligence (AmI) and in particular the area of Ambient Assisted Living (AAL) offer a feasible response, allowing the creation of human-centric smart environments that are sensitive and responsive to the needs and behaviours of the user. In such a scenario, understand what a human being is doing, if and how he/she is interacting with specific objects, or whether abnormal situations are occurring is critical. This thesis is focused on two related research areas of AAL: the development of innovative vision-based techniques for human action recognition and the remote monitoring of users behaviour in smart environments. The former topic is addressed through different approaches based on data extracted from RGB-D sensors. A first algorithm exploiting skeleton joints orientations is proposed. This approach is extended through a multi-modal strategy that includes the RGB channel to define a number of temporal images, capable of describing the time evolution of actions. Finally, the concept of template co-updating concerning action recognition is introduced. Indeed, exploiting different data categories (e.g., skeleton and RGB information) improve the effectiveness of template updating through co-updating techniques. The action recognition algorithms have been evaluated on CAD-60 and CAD-120, achieving results comparable with the state-of-the-art. Moreover, due to the lack of datasets including skeleton joints orientations, a new benchmark named Office Activity Dataset has been internally acquired and released. Regarding the second topic addressed, the goal is to provide a detailed implementation strategy concerning a generic Internet of Things monitoring platform that could be used for checking users' behaviour in AmI/AAL contexts

CHORUS Deliverable 2.2: Second report - identification of multi-disciplinary key issues for gap analysis toward EU multimedia search engines roadmap

After addressing the state-of-the-art during the first year of Chorus and establishing the existing landscape in multimedia search engines, we have identified and analyzed gaps within European research effort during our second year. In this period we focused on three directions, notably technological issues, user-centred issues and use-cases and socio- economic and legal aspects. These were assessed by two central studies: firstly, a concerted vision of functional breakdown of generic multimedia search engine, and secondly, a representative use-cases descriptions with the related discussion on requirement for technological challenges. Both studies have been carried out in cooperation and consultation with the community at large through EC concertation meetings (multimedia search engines cluster), several meetings with our Think-Tank, presentations in international conferences, and surveys addressed to EU projects coordinators as well as National initiatives coordinators. Based on the obtained feedback we identified two types of gaps, namely core technological gaps that involve research challenges, and “enablers”, which are not necessarily technical research challenges, but have impact on innovation progress. New socio-economic trends are presented as well as emerging legal challenges

An Outlook into the Future of Egocentric Vision

What will the future be? We wonder! In this survey, we explore the gap between current research in egocentric vision and the ever-anticipated future, where wearable computing, with outward facing cameras and digital overlays, is expected to be integrated in our every day lives. To understand this gap, the article starts by envisaging the future through character-based stories, showcasing through examples the limitations of current technology. We then provide a mapping between this future and previously defined research tasks. For each task, we survey its seminal works, current state-of-the-art methodologies and available datasets, then reflect on shortcomings that limit its applicability to future research. Note that this survey focuses on software models for egocentric vision, independent of any specific hardware. The paper concludes with recommendations for areas of immediate explorations so as to unlock our path to the future always-on, personalised and life-enhancing egocentric vision.Comment: We invite comments, suggestions and corrections here: https://openreview.net/forum?id=V3974SUk1

Privacy Intelligence: A Survey on Image Sharing on Online Social Networks

Image sharing on online social networks (OSNs) has become an indispensable part of daily social activities, but it has also led to an increased risk of privacy invasion. The recent image leaks from popular OSN services and the abuse of personal photos using advanced algorithms (e.g. DeepFake) have prompted the public to rethink individual privacy needs when sharing images on OSNs. However, OSN image sharing itself is relatively complicated, and systems currently in place to manage privacy in practice are labor-intensive yet fail to provide personalized, accurate and flexible privacy protection. As a result, an more intelligent environment for privacy-friendly OSN image sharing is in demand. To fill the gap, we contribute a systematic survey of 'privacy intelligence' solutions that target modern privacy issues related to OSN image sharing. Specifically, we present a high-level analysis framework based on the entire lifecycle of OSN image sharing to address the various privacy issues and solutions facing this interdisciplinary field. The framework is divided into three main stages: local management, online management and social experience. At each stage, we identify typical sharing-related user behaviors, the privacy issues generated by those behaviors, and review representative intelligent solutions. The resulting analysis describes an intelligent privacy-enhancing chain for closed-loop privacy management. We also discuss the challenges and future directions existing at each stage, as well as in publicly available datasets.Comment: 32 pages, 9 figures. Under revie

Deep Learning for Sensor-based Human Activity Recognition: Overview, Challenges and Opportunities

The vast proliferation of sensor devices and Internet of Things enables the applications of sensor-based activity recognition. However, there exist substantial challenges that could influence the performance of the recognition system in practical scenarios. Recently, as deep learning has demonstrated its effectiveness in many areas, plenty of deep methods have been investigated to address the challenges in activity recognition. In this study, we present a survey of the state-of-the-art deep learning methods for sensor-based human activity recognition. We first introduce the multi-modality of the sensory data and provide information for public datasets that can be used for evaluation in different challenge tasks. We then propose a new taxonomy to structure the deep methods by challenges. Challenges and challenge-related deep methods are summarized and analyzed to form an overview of the current research progress. At the end of this work, we discuss the open issues and provide some insights for future directions

Bridging the gap between emotion and joint action

Our daily human life is filled with a myriad of joint action moments, be it children playing, adults working together (i.e., team sports), or strangers navigating through a crowd. Joint action brings individuals (and embodiment of their emotions) together, in space and in time. Yet little is known about how individual emotions propagate through embodied presence in a group, and how joint action changes individual emotion. In fact, the multi-agent component is largely missing from neuroscience-based approaches to emotion, and reversely joint action research has not found a way yet to include emotion as one of the key parameters to model socio-motor interaction. In this review, we first identify the gap and then stockpile evidence showing strong entanglement between emotion and acting together from various branches of sciences. We propose an integrative approach to bridge the gap, highlight five research avenues to do so in behavioral neuroscience and digital sciences, and address some of the key challenges in the area faced by modern societies

Data fusion strategies for energy efficiency in buildings: Overview, challenges and novel orientations

Recently, tremendous interest has been devoted to develop data fusion strategies for energy efficiency in buildings, where various kinds of information can be processed. However, applying the appropriate data fusion strategy to design an efficient energy efficiency system is not straightforward; it requires a priori knowledge of existing fusion strategies, their applications and their properties. To this regard, seeking to provide the energy research community with a better understanding of data fusion strategies in building energy saving systems, their principles, advantages, and potential applications, this paper proposes an extensive survey of existing data fusion mechanisms deployed to reduce excessive consumption and promote sustainability. We investigate their conceptualizations, advantages, challenges and drawbacks, as well as performing a taxonomy of existing data fusion strategies and other contributing factors. Following, a comprehensive comparison of the state-of-the-art data fusion based energy efficiency frameworks is conducted using various parameters, including data fusion level, data fusion techniques, behavioral change influencer, behavioral change incentive, recorded data, platform architecture, IoT technology and application scenario. Moreover, a novel method for electrical appliance identification is proposed based on the fusion of 2D local texture descriptors, where 1D power signals are transformed into 2D space and treated as images. The empirical evaluation, conducted on three real datasets, shows promising performance, in which up to 99.68% accuracy and 99.52% F1 score have been attained. In addition, various open research challenges and future orientations to improve data fusion based energy efficiency ecosystems are explored