A model for dynamic communicators

We develop and test an intuitively simple dynamic network model to describe the type of time-varying connectivity structure present in many technological settings. The model assumes that nodes have an inherent hierarchy governing the emergence of new connections. This idea draws on newly established concepts in online human behaviour concerning the existence of discussion catalysts, who initiate long threads, and online leaders, who trigger feedback. We show that the model captures an important property found in e-mail and voice call data – ‘dynamic communicators’ with sufficient foresight or impact to generate effective links and having an influence that is grossly underestimated by static measures based on snaphots or aggregated data

Inferring diffusion in single live cells at the single molecule level

The movement of molecules inside living cells is a fundamental feature of biological processes. The ability to both observe and analyse the details of molecular diffusion in vivo at the single molecule and single cell level can add significant insight into understanding molecular architectures of diffusing molecules and the nanoscale environment in which the molecules diffuse. The tool of choice for monitoring dynamic molecular localization in live cells is fluorescence microscopy, especially so combining total internal reflection fluorescence (TIRF) with the use of fluorescent protein (FP) reporters in offering exceptional imaging contrast for dynamic processes in the cell membrane under relatively physiological conditions compared to competing single molecule techniques. There exist several different complex modes of diffusion, and discriminating these from each other is challenging at the molecular level due to underlying stochastic behaviour. Analysis is traditionally performed using mean square displacements of tracked particles, however, this generally requires more data points than is typical for single FP tracks due to photophysical instability. Presented here is a novel approach allowing robust Bayesian ranking of diffusion processes (BARD) to discriminate multiple complex modes probabilistically. It is a computational approach which biologists can use to understand single molecule features in live cells.Comment: combined ms (1-37 pages, 8 figures) and SI (38-55, 3 figures

User benefits and funding strategies

A three-step, systematic method is described for selecting relevant and highly beneficial payloads for the Interim Upper Stage (IUS) that will be used with the space shuttle until the space tug becomes available. Viable cost-sharing strategies which would maximize the number of IUS payloads and the benefits obtainable under a limited NASA budget were also determined

Comparison of group recommendation algorithms

In recent years recommender systems have become the common tool to handle the information overload problem of educational and informative web sites, content delivery systems, and online shops. Although most recommender systems make suggestions for individual users, in many circumstances the selected items (e.g., movies) are not intended for personal usage but rather for consumption in groups. This paper investigates how effective group recommendations for movies can be generated by combining the group members' preferences (as expressed by ratings) or by combining the group members' recommendations. These two grouping strategies, which convert traditional recommendation algorithms into group recommendation algorithms, are combined with five commonly used recommendation algorithms to calculate group recommendations for different group compositions. The group recommendations are not only assessed in terms of accuracy, but also in terms of other qualitative aspects that are important for users such as diversity, coverage, and serendipity. In addition, the paper discusses the influence of the size and composition of the group on the quality of the recommendations. The results show that the grouping strategy which produces the most accurate results depends on the algorithm that is used for generating individual recommendations. Therefore, the paper proposes a combination of grouping strategies which outperforms each individual strategy in terms of accuracy. Besides, the results show that the accuracy of the group recommendations increases as the similarity between members of the group increases. Also the diversity, coverage, and serendipity of the group recommendations are to a large extent dependent on the used grouping strategy and recommendation algorithm. Consequently for (commercial) group recommender systems, the grouping strategy and algorithm have to be chosen carefully in order to optimize the desired quality metrics of the group recommendations. The conclusions of this paper can be used as guidelines for this selection process

Signed Distance-based Deep Memory Recommender

Personalized recommendation algorithms learn a user's preference for an item by measuring a distance/similarity between them. However, some of the existing recommendation models (e.g., matrix factorization) assume a linear relationship between the user and item. This approach limits the capacity of recommender systems, since the interactions between users and items in real-world applications are much more complex than the linear relationship. To overcome this limitation, in this paper, we design and propose a deep learning framework called Signed Distance-based Deep Memory Recommender, which captures non-linear relationships between users and items explicitly and implicitly, and work well in both general recommendation task and shopping basket-based recommendation task. Through an extensive empirical study on six real-world datasets in the two recommendation tasks, our proposed approach achieved significant improvement over ten state-of-the-art recommendation models

CHORUS Deliverable 2.1: State of the Art on Multimedia Search Engines

Based on the information provided by European projects and national initiatives related to multimedia search as well as domains experts that participated in the CHORUS Think-thanks and workshops, this document reports on the state of the art related to multimedia content search from, a technical, and socio-economic perspective. The technical perspective includes an up to date view on content based indexing and retrieval technologies, multimedia search in the context of mobile devices and peer-to-peer networks, and an overview of current evaluation and benchmark inititiatives to measure the performance of multimedia search engines. From a socio-economic perspective we inventorize the impact and legal consequences of these technical advances and point out future directions of research

Quality of Life, Firm Productivity, and the Value of Amenities across Canadian Cities

This paper presents the first hedonic general-equilibrium estimates of quality-of-life and firm productivity differences across Canadian cities, using data on local wages and housing costs. These estimates account for the unobservability of land rents and geographic differences in federal and provincial tax burdens. Quality of life estimates are generally higher in Canada’s larger cities: Victoria, Vancouver are the nicest overall, particularly for Anglophones, while Montreal and Ottawa are the nicest for Francophones. These estimates are positively correlated with estimates in the popular literature and may be explained by differences in climate. Toronto is Canada’s most productive city; Vancouver, the overall most valued city.quality of life, firm productivity, cost-of-living, firm productivity, compensating wage differentials

Spatial Relations and Natural-Language Semantics for Indoor Scenes

Over the past 15 years, there have been increased efforts to represent and communicate spatial information about entities within indoor environments. Automated annotation of information about indoor environments is needed for natural-language processing tasks, such as spatially anchoring events, tracking objects in motion, scene descriptions, and interpretation of thematic places in relationship to confirmed locations. Descriptions of indoor scenes often require a fine granularity of spatial information about the meaning of natural-language spatial utterances to improve human-computer interactions and applications for the retrieval of spatial information. The development needs of these systems provide a rationale as to why—despite an extensive body of research in spatial cognition and spatial linguistics—it is still necessary to investigate basic understandings of how humans conceptualize and communicate about objects and structures in indoor space. This thesis investigates the alignment of conceptual spatial relations and naturallanguage (NL) semantics in the representation of indoor space. The foundation of this work is grounded in spatial information theory as well as spatial cognition and spatial linguistics. In order to better understand how to align computational models and NL expressions about indoor space, this dissertation used an existing dataset of indoor scene descriptions to investigate patterns in entity identification, spatial relations, and spatial preposition use within vista-scale indoor settings. Three human-subject experiments were designed and conducted within virtual indoor environments. These experiments investigate alignment of human-subject NL expressions for a sub-set of conceptual spatial relations (contact, disjoint, and partof) within a controlled virtual environment. Each scene was designed to focus participant attention on a single relation depicted in the scene and elicit a spatial preposition term(s) to describe the focal relationship. The major results of this study are the identification of object and structure categories, spatial relationships, and patterns of spatial preposition use in the indoor scene descriptions that were consistent across both open response, closed response and ranking type items. There appeared to be a strong preference for describing scene objects in relation to the structural objects that bound the room depicted in the indoor scenes. Furthermore, for each of the three relations (contact, disjoint, and partof), a small set of spatial prepositions emerged that were strongly preferred by participants at statistically significant levels based on the overall frequency of response, image sorting, and ranking judgments. The use of certain spatial prepositions to describe relations between room structures suggests there may be differences in how indoor vista-scale space is understood in relation to tabletop and geographic scales. Finally, an indoor scene description corpus was developed as a product of this work, which should provide researchers with new human-subject based datasets for training NL algorithms used to generate more accurate and intuitive NL descriptions of indoor scenes