14,526 research outputs found
A First Look at QUIC in the Wild
For the first time since the establishment of TCP and UDP, the Internet
transport layer is subject to a major change by the introduction of QUIC.
Initiated by Google in 2012, QUIC provides a reliable, connection-oriented
low-latency and fully encrypted transport. In this paper, we provide the first
broad assessment of QUIC usage in the wild. We monitor the entire IPv4 address
space since August 2016 and about 46% of the DNS namespace to detected
QUIC-capable infrastructures. Our scans show that the number of QUIC-capable
IPs has more than tripled since then to over 617.59 K. We find around 161K
domains hosted on QUIC-enabled infrastructure, but only 15K of them present
valid certificates over QUIC. Second, we analyze one year of traffic traces
provided by MAWI, one day of a major European tier-1 ISP and from a large IXP
to understand the dominance of QUIC in the Internet traffic mix. We find QUIC
to account for 2.6% to 9.1% of the current Internet traffic, depending on the
vantage point. This share is dominated by Google pushing up to 42.1% of its
traffic via QUIC
Can geocomputation save urban simulation? Throw some agents into the mixture, simmer and wait ...
There are indications that the current generation of simulation models in practical,
operational uses has reached the limits of its usefulness under existing specifications.
The relative stasis in operational urban modeling contrasts with simulation efforts in
other disciplines, where techniques, theories, and ideas drawn from computation and
complexity studies are revitalizing the ways in which we conceptualize, understand,
and model real-world phenomena. Many of these concepts and methodologies are
applicable to operational urban systems simulation. Indeed, in many cases, ideas from
computation and complexity studies—often clustered under the collective term of
geocomputation, as they apply to geography—are ideally suited to the simulation of
urban dynamics. However, there exist several obstructions to their successful use in
operational urban geographic simulation, particularly as regards the capacity of these
methodologies to handle top-down dynamics in urban systems.
This paper presents a framework for developing a hybrid model for urban geographic
simulation and discusses some of the imposing barriers against innovation in this
field. The framework infuses approaches derived from geocomputation and
complexity with standard techniques that have been tried and tested in operational
land-use and transport simulation. Macro-scale dynamics that operate from the topdown
are handled by traditional land-use and transport models, while micro-scale
dynamics that work from the bottom-up are delegated to agent-based models and
cellular automata. The two methodologies are fused in a modular fashion using a
system of feedback mechanisms. As a proof-of-concept exercise, a micro-model of
residential location has been developed with a view to hybridization. The model
mixes cellular automata and multi-agent approaches and is formulated so as to
interface with meso-models at a higher scale
Systems approaches and algorithms for discovery of combinatorial therapies
Effective therapy of complex diseases requires control of highly non-linear
complex networks that remain incompletely characterized. In particular, drug
intervention can be seen as control of signaling in cellular networks.
Identification of control parameters presents an extreme challenge due to the
combinatorial explosion of control possibilities in combination therapy and to
the incomplete knowledge of the systems biology of cells. In this review paper
we describe the main current and proposed approaches to the design of
combinatorial therapies, including the empirical methods used now by clinicians
and alternative approaches suggested recently by several authors. New
approaches for designing combinations arising from systems biology are
described. We discuss in special detail the design of algorithms that identify
optimal control parameters in cellular networks based on a quantitative
characterization of control landscapes, maximizing utilization of incomplete
knowledge of the state and structure of intracellular networks. The use of new
technology for high-throughput measurements is key to these new approaches to
combination therapy and essential for the characterization of control
landscapes and implementation of the algorithms. Combinatorial optimization in
medical therapy is also compared with the combinatorial optimization of
engineering and materials science and similarities and differences are
delineated.Comment: 25 page
Goodbye, ALOHA!
©2016 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.The vision of the Internet of Things (IoT) to interconnect and Internet-connect everyday people, objects, and machines poses new challenges in the design of wireless communication networks. The design of medium access control (MAC) protocols has been traditionally an intense area of research due to their high impact on the overall performance of wireless communications. The majority of research activities in this field deal with different variations of protocols somehow based on ALOHA, either with or without listen before talk, i.e., carrier sensing multiple access. These protocols operate well under low traffic loads and low number of simultaneous devices. However, they suffer from congestion as the traffic load and the number of devices increase. For this reason, unless revisited, the MAC layer can become a bottleneck for the success of the IoT. In this paper, we provide an overview of the existing MAC solutions for the IoT, describing current limitations and envisioned challenges for the near future. Motivated by those, we identify a family of simple algorithms based on distributed queueing (DQ), which can operate for an infinite number of devices generating any traffic load and pattern. A description of the DQ mechanism is provided and most relevant existing studies of DQ applied in different scenarios are described in this paper. In addition, we provide a novel performance evaluation of DQ when applied for the IoT. Finally, a description of the very first demo of DQ for its use in the IoT is also included in this paper.Peer ReviewedPostprint (author's final draft
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