Improving chronic pain management with eHealth and mHealth: study protocol for a randomised controlled trial

INTRODUCTION: Chronic pain has become a matter of public health concern due to its high prevalence and because public costs associated with treatment and disability increase each year. Research suggests that limitations in the traditional assessment of chronic pain patients limit the effectiveness of current medical treatments. The use of technology might serve change patient traditional monitoring into ecological momentary assessments, which might be visualised by physicians live. This study describes a randomised control trial designed to test the utility of a technology-based solution for pain telemonitoring consisting of a smartphone app for patients and a web application for physicians. The goal of this study will be to explore whether this combination of eHealth and mHealth improves the effectiveness of existing pain treatments. METHODS AND ANALYSIS: Participants will be 250 patients randomly assigned to one of these two conditions: treatment-as-usual (TAU) and TAU +app+¿web. All participants will receive the usual treatment for their pain. Only the TAU +app+¿web group use Pain Monitor app, which generates alarms that are sent to the physicians in the face of previously established undesired events. Physicians will be able to monitor app reports using a web application, which might result in an adjustment of treatment. We anticipate that the use of Pain Monitor plus the therapist web will result in a reduction of pain intensity and side effects of the medication. Improvements on secondary outcomes, namely fatigue, mood, pain interference, rescue medication use and quality of life, are also expected. Mixed repeated-measure multivariate analyses of variances will be conducted to investigate whether there are differences between preassessment and postassessment scores as a function of the experimental condition. ETHICS AND DISSEMINATION: Ethical approval from the Hospital General Universitari de Castellon was obtained. The findings will be published in peer-reviewed journals

Efficacy and safety of flash glucose monitoring in patients with type 1 and type 2 diabetes: a systematic review and meta-analysis

INTRODUCTION: Flash glucose monitoring (FGM) is a factory-calibrated sensor-based technology for the measurement of interstitial glucose. We performed a systematic review and meta-analysis to assess its efficacy and safety in patients with type 1 and type 2 diabetes. RESEARCH DESIGN AND METHODS: PubMed, CENTRAL, Scopus and Web of Science were searched in July 2019. Twelve studies with a follow-up longer than 8 weeks, evaluating 2173 patients on prandial insulin, multiple daily insulin injections or continuous subcutaneous insulin infusion were included. The following data were extracted: HbA1c, time in range, time above 180 mg/dL, time below 70 mg/dL, frequency of hypoglycemic events, number of self-monitoring of blood glucose (SMBG) measurements, total daily insulin dose, patient-reported outcomes, adverse events, and discontinuation rate. A comparison with SMBG was conducted. RESULTS: FGM use was associated with a reduction in HbA1c (-0.26% (-3 mmol/mol); p=0.002) from baseline to the last available follow-up, which correlated with HbA1c levels at baseline (-0.4% (-4 mmol/mol) for each 1.0% (11 mmol/mol) of HbA1c above 7.2% (55 mmol/mol)). Also, a decrease in time below 70 mg/dL was found (-0.60 hours/day; p=0.04). Favorable findings in patient-reported outcomes and no device-related serious adverse events were reported. When compared with SMBG, FGM was characterized by no statistically different change in HbA1c (p=0.09), with lower number of SMBG measurements per day (-3.76 n/day; p<0.001) and risk of discontinuation (relative risk=0.42; p=0.001). A limited number of studies, with a heterogeneous design and usually with a short-term follow-up and without specific training, were found. CONCLUSIONS: The present review provides evidence for the use of FGM as an effective strategy for the management of diabetes

A conceptual model for semantically-based e-government portals

Issues of semantic interoperability and service integration for e-government portals are the domain of interest of the present paper. We propose a Conceptual Model for One-Stop e-Government Portals based on the Semantic Web Service technology. We describe our research into building the three basic ontologies and their integration with standard ontologies. The result is a project-independent reusable model. At the same time, we outline a simple methodology for applying the proposed conceptual model into a specific scenario

Shaping the future for primary care education & training project. Education and training needs analysis (ETNA) toolkit: a resource kit and users’ guide

The Education and Training Needs Analysis (ETNA) Toolkit that has been developed as part of an inter university collaboration in the North West of England entitled the ‘Shaping the Future for Primary Care Education and Training’ project. The tool has been developed by the University of Bolton and Lancaster University in collaboration with key stakeholders including representatives from Primary Care Trusts and Social Services across the North Wes

MODELING INFORMATION SYSTEMS FOR EVENT MANAGEMENT

Website that could help event organizer to organize and manage Event wasn’t a new thing. But today most similar portal providing services only for top-level steering committee due to the cost is quite high. This is the background of the author to conduct this research. Using the techniques of data collection, analysis, and several stages of research, it can be concluded that people required the website that could help them not only for organizing the event but also commercializing and helping them reach the customer. This research resulted in the model of event management website that dedicated for event organizers of the event from low to the middle level, where in addition to providing services and sales promotion, the portal also provides services for the evaluation for the event management

Design and implementation of a filter engine for semantic web documents

This report describes our project that addresses the challenge of changes in the semantic web. Some studies have already been done for the so-called adaptive semantic web, such as applying inferring rules. In this study, we apply the technology of Event Notification System (ENS). Treating changes as events, we developed a notification system for such events

Towards Run-Time Verification of Compositions in the Web of Things using Complex Event Processing

Following the vision of the Internet of Things, physical world entities are integrated into virtual world things. Things are expected to become active participants in business and social processes. Then, the Internet of Things could benefit from the Web Service architecture like today’s Web does, so Future ser-vice-oriented Internet things will offer their functionality via service-enabled in-terfaces. In previous work, we demonstrated the need of considering the behav-iour of things to develop applications in a more rigorous way, and we proposed a lightweight model for representing such behaviour. Our methodology relies on the service-oriented paradigm and extends the DPWS profile to specify the order with which things can receive messages. We also proposed a static verifi-cation technique to check whether a mashup of things respects the behaviour, specified at design-time, of the composed things. However, a change in the be-haviour of a thing may cause that some compositions do not fulfill its behaviour anymore. Moreover, given that a thing can receive requests from instances of different mashups at run-time, these requests could violate the behaviour of that thing, even though each mashup fulfills such behaviour, due to the change of state of the thing. To address these issues, we present a proposal based on me-diation techniques and complex event processing to detect and inhibit invalid invocations, so things only receive requests compatible with their behaviour.Work partially supported by projects TIN2008-05932, TIN2012-35669, CSD2007-0004 funded by Spanish Ministry MINECO and FEDER; P11-TIC-7659 funded by Andalusian Government; and Universidad de Málaga, Campus de Excelencia Internacional Andalucía Tec

Use-cases on evolution

This report presents a set of use cases for evolution and reactivity for data in the Web and Semantic Web. This set is organized around three different case study scenarios, each of them is related to one of the three different areas of application within Rewerse. Namely, the scenarios are: “The Rewerse Information System and Portal”, closely related to the work of A3 – Personalised Information Systems; “Organizing Travels”, that may be related to the work of A1 – Events, Time, and Locations; “Updates and evolution in bioinformatics data sources” related to the work of A2 – Towards a Bioinformatics Web