6,146 research outputs found
Real time unsupervised learning of visual stimuli in neuromorphic VLSI systems
Neuromorphic chips embody computational principles operating in the nervous
system, into microelectronic devices. In this domain it is important to
identify computational primitives that theory and experiments suggest as
generic and reusable cognitive elements. One such element is provided by
attractor dynamics in recurrent networks. Point attractors are equilibrium
states of the dynamics (up to fluctuations), determined by the synaptic
structure of the network; a `basin' of attraction comprises all initial states
leading to a given attractor upon relaxation, hence making attractor dynamics
suitable to implement robust associative memory. The initial network state is
dictated by the stimulus, and relaxation to the attractor state implements the
retrieval of the corresponding memorized prototypical pattern. In a previous
work we demonstrated that a neuromorphic recurrent network of spiking neurons
and suitably chosen, fixed synapses supports attractor dynamics. Here we focus
on learning: activating on-chip synaptic plasticity and using a theory-driven
strategy for choosing network parameters, we show that autonomous learning,
following repeated presentation of simple visual stimuli, shapes a synaptic
connectivity supporting stimulus-selective attractors. Associative memory
develops on chip as the result of the coupled stimulus-driven neural activity
and ensuing synaptic dynamics, with no artificial separation between learning
and retrieval phases.Comment: submitted to Scientific Repor
Roadmap on semiconductor-cell biointerfaces.
This roadmap outlines the role semiconductor-based materials play in understanding the complex biophysical dynamics at multiple length scales, as well as the design and implementation of next-generation electronic, optoelectronic, and mechanical devices for biointerfaces. The roadmap emphasizes the advantages of semiconductor building blocks in interfacing, monitoring, and manipulating the activity of biological components, and discusses the possibility of using active semiconductor-cell interfaces for discovering new signaling processes in the biological world
The potential of microelectrode arrays and microelectronics for biomedical research and diagnostics
Planar microelectrode arrays (MEAs) are devices that can be used in biomedical and basic in vitro research to provide extracellular electrophysiological information about biological systems at high spatial and temporal resolution. Complementary metal oxide semiconductor (CMOS) is a technology with which MEAs can be produced on a microscale featuring high spatial resolution and excellent signal-to-noise characteristics. CMOS MEAs are specialized for the analysis of complete electrogenic cellular networks at the cellular or subcellular level in dissociated cultures, organotypic cultures, and acute tissue slices; they can also function as biosensors to detect biochemical events. Models of disease or the response of cellular networks to pharmacological compounds can be studied in vitro, allowing one to investigate pathologies, such as cardiac arrhythmias, memory impairment due to Alzheimer's disease, or vision impairment caused by ganglion cell degeneration in the retin
A Construction Kit for Efficient Low Power Neural Network Accelerator Designs
Implementing embedded neural network processing at the edge requires
efficient hardware acceleration that couples high computational performance
with low power consumption. Driven by the rapid evolution of network
architectures and their algorithmic features, accelerator designs are
constantly updated and improved. To evaluate and compare hardware design
choices, designers can refer to a myriad of accelerator implementations in the
literature. Surveys provide an overview of these works but are often limited to
system-level and benchmark-specific performance metrics, making it difficult to
quantitatively compare the individual effect of each utilized optimization
technique. This complicates the evaluation of optimizations for new accelerator
designs, slowing-down the research progress. This work provides a survey of
neural network accelerator optimization approaches that have been used in
recent works and reports their individual effects on edge processing
performance. It presents the list of optimizations and their quantitative
effects as a construction kit, allowing to assess the design choices for each
building block separately. Reported optimizations range from up to 10'000x
memory savings to 33x energy reductions, providing chip designers an overview
of design choices for implementing efficient low power neural network
accelerators
A proposal for a coordinated effort for the determination of brainwide neuroanatomical connectivity in model organisms at a mesoscopic scale
In this era of complete genomes, our knowledge of neuroanatomical circuitry
remains surprisingly sparse. Such knowledge is however critical both for basic
and clinical research into brain function. Here we advocate for a concerted
effort to fill this gap, through systematic, experimental mapping of neural
circuits at a mesoscopic scale of resolution suitable for comprehensive,
brain-wide coverage, using injections of tracers or viral vectors. We detail
the scientific and medical rationale and briefly review existing knowledge and
experimental techniques. We define a set of desiderata, including brain-wide
coverage; validated and extensible experimental techniques suitable for
standardization and automation; centralized, open access data repository;
compatibility with existing resources, and tractability with current
informatics technology. We discuss a hypothetical but tractable plan for mouse,
additional efforts for the macaque, and technique development for human. We
estimate that the mouse connectivity project could be completed within five
years with a comparatively modest budget.Comment: 41 page
A half century of progress towards a unified neural theory of mind and brain with applications to autonomous adaptive agents and mental disorders
Invited article for the book
Artificial Intelligence in the Age of
Neural Networks and Brain Computing
R. Kozma, C. Alippi, Y. Choe, and F. C. Morabito, Eds.
Cambridge, MA: Academic PressThis article surveys some of the main design principles, mechanisms, circuits, and architectures that have been discovered during a half century of systematic research aimed at developing a unified theory that links mind and brain, and shows how psychological functions arise as emergent properties of brain mechanisms. The article describes a theoretical method that has enabled such a theory to be developed in stages by carrying out a kind of conceptual evolution. It also describes revolutionary computational paradigms like Complementary Computing and Laminar Computing that constrain the kind of unified theory that can describe the autonomous adaptive intelligence that emerges from advanced brains. Adaptive Resonance Theory, or ART, is one of the core models that has been discovered in this way. ART proposes how advanced brains learn to attend, recognize, and predict objects and events in a changing world that is filled with unexpected events. ART is not, however, a “theory of everything” if only because, due to Complementary Computing, different matching and learning laws tend to support perception and cognition on the one hand, and spatial representation and action on the other. The article mentions why a theory of this kind may be useful in the design of autonomous adaptive agents in engineering and technology. It also notes how the theory has led to new mechanistic insights about mental disorders such as autism, medial temporal amnesia, Alzheimer’s disease, and schizophrenia, along with mechanistically informed proposals about how their symptoms may be ameliorated
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