Freeze-drying modeling and monitoring using a new neuro-evolutive technique

This paper is focused on the design of a black-box model for the process of freeze-drying of pharmaceuticals. A new methodology based on a self-adaptive differential evolution scheme is combined with a back-propagation algorithm, as local search method, for the simultaneous structural and parametric optimization of the model represented by a neural network. Using the model of the freeze-drying process, both the temperature and the residual ice content in the product vs. time can be determine off-line, given the values of the operating conditions (the temperature of the heating shelf and the pressure in the drying chamber). This makes possible to understand if the maximum temperature allowed by the product is trespassed and when the sublimation drying is complete, thus providing a valuable tool for recipe design and optimization. Besides, the black box model can be applied to monitor the freeze-drying process: in this case, the measurement of product temperature is used as input variable of the neural network in order to provide in-line estimation of the state of the product (temperature and residual amount of ice). Various examples are presented and discussed, thus pointing out the strength of the too

DIFFERENTIAL EVOLUTION FOR OPTIMIZATION OF PID GAIN IN ELECTRICAL DISCHARGE MACHINING CONTROL SYSTEM

ABSTRACT PID controller of servo control system maintains the gap between Electrode and workpiece in Electrical Dis- charge Machining (EDM). Capability of the controller is significant since machining process is a stochastic phenomenon and physical behaviour of the discharge is unpredictable. Therefore, a Proportional Integral Derivative (PID) controller using Differential Evolution (DE) algorithm is designed and applied to an EDM servo actuator system in order to find suitable gain parameters. Simulation results verify the capabilities and effectiveness of the DE algorithm to search the best configuration of PID gain to maintain the electrode position. Keywords: servo control system; electrical discharge machining; proportional integral derivative; con- troller tuning; differential evolution

Fuzzy Differential Evolution Algorithm

The Differential Evolution (DE) algorithm is a powerful search technique for solving global optimization problems over continuous space. The search initialization for this algorithm does not adequately capture vague preliminary knowledge from the problem domain. This thesis proposes a novel Fuzzy Differential Evolution (FDE) algorithm, as an alternative approach, where the vague information of the search space can be represented and used to deliver a more efficient search. The proposed FDE algorithm utilizes fuzzy set theory concepts to modify the traditional DE algorithm search initialization and mutation components. FDE, alongside other key DE features, is implemented in a convenient decision support system software package. Four benchmark functions are used to demonstrate performance of the new FDE and its practical utility. Additionally, the application of the algorithm is illustrated through a water management case study problem. The new algorithm shows faster convergence for most of the benchmark functions

Evolutionary Computation

This book presents several recent advances on Evolutionary Computation, specially evolution-based optimization methods and hybrid algorithms for several applications, from optimization and learning to pattern recognition and bioinformatics. This book also presents new algorithms based on several analogies and metafores, where one of them is based on philosophy, specifically on the philosophy of praxis and dialectics. In this book it is also presented interesting applications on bioinformatics, specially the use of particle swarms to discover gene expression patterns in DNA microarrays. Therefore, this book features representative work on the field of evolutionary computation and applied sciences. The intended audience is graduate, undergraduate, researchers, and anyone who wishes to become familiar with the latest research work on this field

Optimisation of Mobile Communication Networks - OMCO NET

The mini conference “Optimisation of Mobile Communication Networks” focuses on advanced methods for search and optimisation applied to wireless communication networks. It is sponsored by Research & Enterprise Fund Southampton Solent University. The conference strives to widen knowledge on advanced search methods capable of optimisation of wireless communications networks. The aim is to provide a forum for exchange of recent knowledge, new ideas and trends in this progressive and challenging area. The conference will popularise new successful approaches on resolving hard tasks such as minimisation of transmit power, cooperative and optimal routing