Review on DNA Cryptography

Cryptography is the science that secures data and communication over the network by applying mathematics and logic to design strong encryption methods. In the modern era of e-business and e-commerce the protection of confidentiality, integrity and availability (CIA triad) of stored information as well as of transmitted data is very crucial. DNA molecules, having the capacity to store, process and transmit information, inspires the idea of DNA cryptography. This combination of the chemical characteristics of biological DNA sequences and classical cryptography ensures the non-vulnerable transmission of data. In this paper we have reviewed the present state of art of DNA cryptography.Comment: 31 pages, 12 figures, 6 table

A perceptual hash function to store and retrieve large scale DNA sequences

This paper proposes a novel approach for storing and retrieving massive DNA sequences.. The method is based on a perceptual hash function, commonly used to determine the similarity between digital images, that we adapted for DNA sequences. Perceptual hash function presented here is based on a Discrete Cosine Transform Sign Only (DCT-SO). Each nucleotide is encoded as a fixed gray level intensity pixel and the hash is calculated from its significant frequency characteristics. This results to a drastic data reduction between the sequence and the perceptual hash. Unlike cryptographic hash functions, perceptual hashes are not affected by "avalanche effect" and thus can be compared. The similarity distance between two hashes is estimated with the Hamming Distance, which is used to retrieve DNA sequences. Experiments that we conducted show that our approach is relevant for storing massive DNA sequences, and retrieving them

Improving random number generators by chaotic iterations. Application in data hiding

In this paper, a new pseudo-random number generator (PRNG) based on chaotic iterations is proposed. This method also combines the digits of two XORshifts PRNGs. The statistical properties of this new generator are improved: the generated sequences can pass all the DieHARD statistical test suite. In addition, this generator behaves chaotically, as defined by Devaney. This makes our generator suitable for cryptographic applications. An illustration in the field of data hiding is presented and the robustness of the obtained data hiding algorithm against attacks is evaluated.Comment: 6 pages, 8 figures, In ICCASM 2010, Int. Conf. on Computer Application and System Modeling, Taiyuan, China, pages ***--***, October 201

SecMon: End-to-End Quality and Security Monitoring System

The Voice over Internet Protocol (VoIP) is becoming a more available and popular way of communicating for Internet users. This also applies to Peer-to-Peer (P2P) systems and merging these two have already proven to be successful (e.g. Skype). Even the existing standards of VoIP provide an assurance of security and Quality of Service (QoS), however, these features are usually optional and supported by limited number of implementations. As a result, the lack of mandatory and widely applicable QoS and security guaranties makes the contemporary VoIP systems vulnerable to attacks and network disturbances. In this paper we are facing these issues and propose the SecMon system, which simultaneously provides a lightweight security mechanism and improves quality parameters of the call. SecMon is intended specially for VoIP service over P2P networks and its main advantage is that it provides authentication, data integrity services, adaptive QoS and (D)DoS attack detection. Moreover, the SecMon approach represents a low-bandwidth consumption solution that is transparent to the users and possesses a self-organizing capability. The above-mentioned features are accomplished mainly by utilizing two information hiding techniques: digital audio watermarking and network steganography. These techniques are used to create covert channels that serve as transport channels for lightweight QoS measurement's results. Furthermore, these metrics are aggregated in a reputation system that enables best route path selection in the P2P network. The reputation system helps also to mitigate (D)DoS attacks, maximize performance and increase transmission efficiency in the network.Comment: Paper was presented at 7th international conference IBIZA 2008: On Computer Science - Research And Applications, Poland, Kazimierz Dolny 31.01-2.02 2008; 14 pages, 5 figure

The Promising Viral Threat to Bacterial Resistance: The Uncertain Patentability of Phage Therapeutics and the Necessity of Alternative Incentives

Bacteriophages, or “phages,” are a category of highly adept and adaptable viruses that can infect and kill bacteria. With concerns over the burgeoning antibiotic-resistance crisis looming in recent years, scientists and policymakers have expressed a growing interest in developing novel treatments for bacterial infections that utilize bacteriophages. Because of the great expense associated with bringing a new drug to market, patents are usually considered the gold standard for incentivizing research and development in the pharmaceutical field. Absent such strong protection for a developer’s front end investment, pharmaceutical development remains financially risky and unattractive. Unfortunately, recent Supreme Court jurisprudence analyzing patentable subject matter under 35 U.S.C. § 101 has cast doubt on whether phage therapeutics would be eligible for strong patent protection. In order for the promise of phage therapeutics to become a reality, alternative protections or incentives are likely necessary. Such a framework would likely include trade secrecy, regulatory exclusivities, research support, alternative payment models, or some combination thereof

Systematizing Genome Privacy Research: A Privacy-Enhancing Technologies Perspective

Rapid advances in human genomics are enabling researchers to gain a better understanding of the role of the genome in our health and well-being, stimulating hope for more effective and cost efficient healthcare. However, this also prompts a number of security and privacy concerns stemming from the distinctive characteristics of genomic data. To address them, a new research community has emerged and produced a large number of publications and initiatives. In this paper, we rely on a structured methodology to contextualize and provide a critical analysis of the current knowledge on privacy-enhancing technologies used for testing, storing, and sharing genomic data, using a representative sample of the work published in the past decade. We identify and discuss limitations, technical challenges, and issues faced by the community, focusing in particular on those that are inherently tied to the nature of the problem and are harder for the community alone to address. Finally, we report on the importance and difficulty of the identified challenges based on an online survey of genome data privacy expertsComment: To appear in the Proceedings on Privacy Enhancing Technologies (PoPETs), Vol. 2019, Issue

The Promising Viral Threat to Bacterial Resistance: The Uncertain Patentability of Phage Therapeutics and the Necessity of Alternative Incentives

Bacteriophages, or “phages,” are a category of highly adept and adaptable viruses that can infect and kill bacteria. With concerns over the burgeoning antibiotic-resistance crisis looming in recent years, scientists and policymakers have expressed a growing interest in developing novel treatments for bacterial infections that utilize bacteriophages. Because of the great expense associated with bringing a new drug to market, patents are usually considered the gold standard for incentivizing research and development in the pharmaceutical field. Absent such strong protection for a developer’s front end investment, pharmaceutical development remains financially risky and unattractive. Unfortunately, recent Supreme Court jurisprudence analyzing patentable subject matter under 35 U.S.C. § 101 has cast doubt on whether phage therapeutics would be eligible for strong patent protection. In order for the promise of phage therapeutics to become a reality, alternative protections or incentives are likely necessary. Such a framework would likely include trade secrecy, regulatory exclusivities, research support, alternative payment models, or some combination thereof

A forensics software toolkit for DNA steganalysis.

Recent advances in genetic engineering have allowed the insertion of artificial DNA strands into the living cells of organisms. Several methods have been developed to insert information into a DNA sequence for the purpose of data storage, watermarking, or communication of secret messages. The ability to detect, extract, and decode messages from DNA is important for forensic data collection and for data security. We have developed a software toolkit that is able to detect the presence of a hidden message within a DNA sequence, extract that message, and then decode it. The toolkit is able to detect, extract, and decode messages that have been encoded with a variety of different coding schemes. The goal of this project is to enable our software toolkit to determine with which coding scheme a message has been encoded in DNA and then to decode it. The software package is able to decode messages that have been encoded with every variation of most of the coding schemes described in this document. The software toolkit has two different options for decoding that can be selected by the user. The first is a frequency analysis approach that is very commonly used in cryptanalysis. This approach is very fast, but is unable to decode messages shorter than 200 words accurately. The second option is using a Genetic Algorithm (GA) in combination with a Wisdom of Artificial Crowds (WoAC) technique. This approach is very time consuming, but can decode shorter messages with much higher accuracy