Lymphocele Management: A Pictorial Review of Lymphocele Treatment

Lymphocele represents a quite frequent complication of surgical treatments that involve kidneys, lymphadenectomy, and pelvic organs. It can also arise after pelvic trauma, or due to infectious diseases. Aim of this review is to give a pictorial evaluation on current epidemiology, pathophysiology, clinical presentation, diagnosis of lymphocele, with particular attention to possible treatments, considering the standard management, but also the new available alternatives, which arose in the last years. All studies were identified by searching from electronic databases of Pubmed. We used the following keywords to search the database: lymphocele, symptoms, pathophysiology, infection, treatment. All the articles chosen were in English

Multispecies Discrimination of Seals (Pinnipeds) using Hidden Markov Models (HMMs)

Hidden Markov Models (HMMs) were developed and implemented for the discrimination of 5 available Seals (Pinnipeds), namely the Bearded Seal (Erignathus barbatus), Harp Seal (Pagophilus groenlandicus), Leopard Seal (Hydrurga leptonyx), Ross Seal (Ommatophoca rossii), and Weddell Seal (Leptonychotes weddellii). The main objectives of the experiments were to study the impact of the frame size and step size and number of states for feature extraction and acoustic models on classification accuracy. Based on the experiments using Mel-Frequency Cepstral Coefficients (MFCCs) extracted from the vocalizations (15 ms frame size and 4 ms step size), HMMs containing 20 states with single underlying Gaussian Mixture Model (GMM) produced discrimination of 95.77%. From the results, the framework could be applied to analysis for other marine mammals for both classification and detection of vocalizations and species

The The Frigging Kinship Between Prostate Carcinogenesis and the Genomic Landscape of Indian Males

Prostate Cancer (PCa) is a major global health issue in men over 50 years of age, arising due to complex and often population-specific interactions between genes, environment, and lifestyle. According to GLOBOCAN, PCa incidence in India is on the rise, albeit at a slower rate than that of the global average. This review delves deep into the nuanced relationship between PCa and the genomic landscape of Indian males. The study thoroughly reviews the epidemiology of PCa and examines the contribution of the genetic determinants like polymorphisms, mutations, and methylation patterns; microbial infections as well as the influence of lifestyle habits like diet, smoking, and drinking on the progress and manifestation of cancer among Indian males, thus intending to provide a holistic understanding of the complex interplay driving the malady. This knowledge would not only help us understand the disease mechanisms but also provide a basis for personalized diagnostic, therapeutic, and preventive strategies tailored to India's unique genetic and environmental landscape

Nonlinear Curve Fitting to Measurement Points with WTLS Method Using Approximation of Linear Model

The paper presents an approximate method of fitting measurement points to parameterized arbitrary nonlinear curves described by complex equations, even implicit ones, the most commonly used method of least squares in general WTLS. An approximation of a linear model is used here, in which the laws of propagation of error and propagation of uncertainty are true, so that only the first derivative of the transforming function is relevant. The effectiveness of the method has been demonstrated in several numerical examples. The method was verified on several nonlinear functions using the iterative algorithm by Monte Carlo propagation of distribution and the classical method based on the Levenberg-Marquardt algorithm for nonlinear optimization

Does Dolutegravir-Based Treatment in HIV-Infected Diabetic Individuals Require More Intensive Cardiovascular Health Monitoring: A Point of Concern for Developing Nations

We are all aware that obesity is a growing health problem globally. An estimated 600 million adults are affected with some form of obesity-related metabolic complications worldwide. It increases cardiovascular disease, diabetes mellitus, chronic kidney disease, nonalcoholic fatty liver disease, and cancer in the long run. Human immunodeficiency virus (HIV) infection is a common occurrence throughout the World. Developed countries can access early diagnosis, standardized treatment protocols, and close monitoring. It not only prevents incidences of opportunistic infections but also takes care of non-infective complications. On the contrary, lack of education, awareness, and access to good healthcare facilities are often responsible for delayed diagnosis and advanced disease at presentation. Even those who are initiated on therapy also have persistent modifiable risk factors for cardiovascular events. The Importance of regular exercise, a healthy diet, and tight control of blood sugar, hypertension, and dyslipidemia are often under-practiced and must be stressed

HUBO & QUBO and Prime Factorization

This document details the methodology and steps taken to convert Higher Order Unconstrained Binary Optimization (HUBO) models into Quadratic Unconstrained Binary Optimization (QUBO) models. The focus is primarily on prime factorization problems; a critical and computationally intensive task relevant in various domains including cryptography, optimization, and number theory. The conversion from Higher-Order Binary Optimization (HUBO) to Quadratic Unconstrained Binary Optimization (QUBO) models is crucial for harnessing the capabilities of advanced computing methodologies, particularly quantum computing and DYNEX neuromorphic computing. Quantum computing offers potential exponential speedups for specific problems through its intrinsic parallelism capabilities. Conversely, DYNEX neuromorphic computing enhances efficiency and accelerates the resolution of intricate, pattern-oriented tasks by simulating memristors in GPUs, employing a highly decentralized approach, via Blockchain technology. This transformation enables the exploitation of these cutting-edge computing paradigms to address complex optimization challenges effectively. Through detailed explanations, mathematical formulations, and algorithmic strategies, this document aims to provide a comprehensive guide to understanding and implementing the conversion process from HUBO to QUBO. It underscores the importance of such transformations in making prime factorization computationally feasible on both existing classical computers and emerging computing technologies

A Comparative Genomic Analysis of Georgenia sps. for Mining of LysR Transcriptional Regulator Sequences

Georgenia is a genus belonging to the actinomycetes group. The genera comprise only 33 poorly characterized species with reference genomes of 10 distinct species. However, none of the species is well characterized for their genome characteristics. Our laboratory isolate from tomato plant leaf was identified and sequenced for identification and found to be Georgenia sp. Later genomic analysis revealed many functional genes having characteristic functions to be analysed. The source of isolation raised the possibility of having functional genes to enhance senescence or having plant pathogenic activity by Georgenia sp. SUBG003. To explore in silico presence of these genes or gene pools genomic islands were identified and analysed for our isolate and other 10 reference genomes of the Georgenia genus. Genomic islands were further explored for transcription regulators and finally, LysR transcriptional regulator sequences were extracted and a phylogeny among sequences was built from multiple sequence alignment

Toward the Development of a Hybrid Active and Measuring Exoskeleton for Upper Limbs of Heavy-duty Harbor Workers

The paper presents the study of a novel exoskeleton designed for the upper limbs of heavy-duty port operators responsible for lashing containers. This exoskeleton is designed to measure initially its configuration and operational times, once positioned on the workers, to pass to a partial activeness introducing motors for the shoulder, the intra-extra rotation of the forearm, and the elbow. The key concept revolves around the shoulder joint, with particular emphasis on the scapula and its motion. The scapula plays a fundamental role in moving the center of rotation of the humerus, contributing to its exceptional mobility. The fundamental objective is to develop a system that provides support for the vertical motion of the operator's arms, with a specific focus on allowing initially the vertical motion of the scapula to remain unrestricted. This approach aims to collect essential data, which, in a subsequent phase, will likely enable the addition of vertical support to the scapula, possibly with the assistance of AI. Meanwhile, the horizontal motion will consistently be left unrestricted. This exoskeleton design is inspired by previous work that conceptualized a fully measuring exoskeleton, and a corresponding patent application has been presented

Unveiling a Novel Frontier: Exploring Creatine Applications in Diabetes Management

In the dynamic realm of diabetes management, the quest for innovative strategies continually evolves. This article embarks on an exploration of a groundbreaking frontier, introducing a new approach that extends beyond conventional paradigms. We delve into the intriguing intersection of creatine applications and diabetes care, unveiling a novel perspective that holds potential to redefine how we approach the multifaceted challenges posed by this metabolic condition. Traditionally renowned for its role in enhancing muscular energy metabolism, creatine has emerged from the realms of sports nutrition to captivate the attention of researchers and practitioners alike in the field of diabetes management. This paradigm shift invites us to reconsider the scope of creatine supplementation, moving beyond its established association with athletic performance to explore its nuanced impact on glucose regulation and insulin sensitivity in individuals grappling with diabetes. As we navigate this uncharted territory, this article aims to provide a comprehensive overview of the intricate interplay between creatine and diabetes, weaving together current research findings, emerging treatment trends, and the potential synergies that could shape the future of diabetes care. From the molecular intricacies of energy metabolism to the broader landscape of contemporary diabetes treatments, our exploration seeks to illuminate a path towards a more holistic and personalized approach to diabetes management

Inferior Trapezius Muscle Agenesis and Scapular Dyskinesis in a 58 Year-Old Black Male Donor: A Cadaveric Case Report

A functionally significant abnormality was observed in a 58 year-old Black male donor with a cause of death of thyroid cancer. He exhibited left inferior trapezius muscle agenesis as well as scapular dyskinesis. The left scapula is shown pressing into the adjacent vertebral bodies of C7 and T1, which resulted in deviations in the location of the left semispinalis capitis, semispinalis cervicis, and splenius cervicis muscles.  This resulted in compromise of the left levator scapulae muscle. It is suspected that these abnormalities would have resulted in functional limitations in arm movement, particularly in adduction. A literature review was completed to understand the significance of these abnormalities