Impaired Postural Control Reduces Sit-to-Stand-to-Sit Performance in Individuals with Chronic Obstructive Pulmonary Disease

Abstract Background: Functional activities, such as the sit-to-stand-to-sit (STSTS) task, are often impaired in individuals with chronic obstructive pulmonary disease (COPD). The STSTS task places a high demand on the postural control system, which has been shown to be impaired in individuals with COPD. It remains unknown whether postural control deficits contribute to the decreased STSTS performance in individuals with COPD. Methods: Center of pressure displacement was determined in 18 individuals with COPD and 18 age/gender-matched controls during five consecutive STSTS movements with vision occluded. The total duration, as well as the duration of each sit, sit-to-stand, stand and stand-to-sit phase was recorded. Results: Individuals with COPD needed significantly more time to perform five consecutive STSTS movements compared to healthy controls (1966 vs. 1364 seconds, respectively; p = 0.001). The COPD group exhibited a significantly longer stand phase (p = 0.028) and stand-to-sit phase (p = 0.001) compared to the control group. In contrast, the duration of the sit phase (p = 0.766) and sit-to-stand phase (p = 0.999) was not different between groups. Conclusions: Compared to healthy individuals, individuals with COPD needed significantly more time to complete those phases of the STSTS task that require the greatest postural control. These findings support the proposition that suboptimal postural control is an important contributor to the decreased STSTS performance in individuals with COPD

Proprioceptive changes impair balance control in individuals with chronic obstructive pulmonary disease

Copyright @ 2013 Janssens et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Introduction: Balance deficits are identified as important risk factors for falling in individuals with chronic obstructive pulmonary disease (COPD). However, the specific use of proprioception, which is of primary importance during balance control, has not been studied in individuals with COPD. The objective was to determine the specific proprioceptive control strategy during postural balance in individuals with COPD and healthy controls, and to assess whether this was related to inspiratory muscle weakness. Methods: Center of pressure displacement was determined in 20 individuals with COPD and 20 age/gender-matched controls during upright stance on an unstable support surface without vision. Ankle and back muscle vibration were applied to evaluate the relative contribution of different proprioceptive signals used in postural control. Results: Individuals with COPD showed an increased anterior-posterior body sway during upright stance (p=0.037). Compared to controls, individuals with COPD showed an increased posterior body sway during ankle muscle vibration (p=0.047), decreased anterior body sway during back muscle vibration (p=0.025), and increased posterior body sway during simultaneous ankle-muscle vibration (p=0.002). Individuals with COPD with the weakest inspiratory muscles showed the greatest reliance on ankle muscle input when compared to the stronger individuals with COPD (p=0.037). Conclusions: Individuals with COPD, especially those with inspiratory muscle weakness, increased their reliance on ankle muscle proprioceptive signals and decreased their reliance on back muscle proprioceptive signals during balance control, resulting in a decreased postural stability compared to healthy controls. These proprioceptive changes may be due to an impaired postural contribution of the inspiratory muscles to trunk stability. Further research is required to determine whether interventions such as proprioceptive training and inspiratory muscle training improve postural balance and reduce the fall risk in individuals with COPD.This work was supported by the Research Foundation – Flanders (FWO) grants 1.5.104.03, G.0674.09, G.0598.09N and G.0871.13N

Associations between gait coordination, variability and motor cortex inhibition in young and older adults

2018 Summer.Includes bibliographical references.Interlimb coordination and mobility (postural sway and turning) diminish with age, posing a risk for gait-related injuries. Further, levels of inhibition within the motor cortex are significantly associated with coordination of the upper extremities in healthy aging, however, it is unknown if this same association exists for lower extremity control. To investigate the relationship between gait coordination and cortical inhibition we measured gait coordination via the phase coordination index and motor cortex inhibition via the cortical silent period in 14 young and 15 older adults. Gait coordination was reduced in older adults across a variety of walking conditions, as was cortical inhibition, solely in the non-dominant motor cortex. Furthermore, young adults were better able to maintain lower extremity coordination and variability with reduced cortical inhibition, whereas older adults with increased cortical inhibition demonstrated better walking performance. These findings suggest a fundamental shift in the relationship between motor cortex inhibition and lower extremity control with age, similar to previous work demonstrating an age-related difference in the association between motor cortex inhibition with bimanual control

PGC-1α affects aging-related changes in muscle and motor function by modulating specific exercise-mediated changes in old mice

The age-related impairment in muscle function results in a drastic decline in motor coordination and mobility in elderly individuals. Regular physical activity is the only efficient intervention to prevent and treat this age-associated degeneration. However, the mechanisms that underlie the therapeutic effect of exercise in this context remain unclear. We assessed whether endurance exercise training in old age is sufficient to affect muscle and motor function. Moreover, as muscle peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) is a key regulatory hub in endurance exercise adaptation with decreased expression in old muscle, we studied the involvement of PGC-1α in the therapeutic effect of exercise in aging. Intriguingly, PGC-1α muscle-specific knockout and overexpression, respectively, precipitated and alleviated specific aspects of aging-related deterioration of muscle function in old mice, while other muscle dysfunctions remained unchanged upon PGC-1α modulation. Surprisingly, we discovered that muscle PGC-1α was not only involved in improving muscle endurance and mitochondrial remodeling, but also phenocopied endurance exercise training in advanced age by contributing to maintaining balance and motor coordination in old animals. Our data therefore suggest that the benefits of exercise, even when performed at old age, extend beyond skeletal muscle and are at least in part mediated by PGC-1α

A Comprehensive Aquatics Program for Spinal Cord Injuries

Water provides a new challenge in the rehabilitation of those with spinal cord injuries. An aquatics program specific to the individual can give invaluable physical, psychological, and therapeutic effects. The inherent properties of water, such as its buoyancy, turbulence, and resistance, give the spinal cord injured person a new freedom of movement and an ideal environment for increasing confidence and learning skills which can be carried over to daily activities. Spinal cord injury aquatics programs in the past have proved successful in several aspects. Goals which are attainable through an aquatics program include increasing respiratory function, range of motion, and muscle strength and improving coordination and mobility while at the same time decreasing spasticity and pain. Social benefits, such as a sense of achievement, self-respect, and self-confidence arise from the experience as the water provides the spinal cord patient with a higher functioning level which is physically and economically beneficial to the individual and ultimately to society. A comprehensive aquatics program for spinal cord injured patients is necessary for outlining components which will enable the physical therapist to design a treatment program which will provide for the optimal independence of the patient. This program can then be tailored to the individual to meet the specific functional needs and goals of the patient

Program for correctional and development work "Development of auditory-zoro-tactile perception of speech and formation of pronunciation in deaf children" for 11-12 cl of general educational institutions (special and inclusive education),training and rehab

Програма з розвитку слухо-зоро-тактильного сприймання мовленнята формування вимови спрямована на формування й удосконалення умінь і навичок слухо-зоро-тактильного сприймання мовлення та формування вимови на індивідуальних заняттях з глухими молодшими учнями. У програмі виокремлено напрями педагогічної діяльності під час занять, що спрямовані на: розвиток слухо-зоро-тактильного сприймання, розвиток слухозорової уваги й пам’яті, формування вимови, координацію та мобільність, власне сенсорну інтеграцію молодших школярів зі зниженим слухом. Це забезпечується застосуванням низки специфічних вправ та завдань. Програма розраховано на сурдопедагогів навчальних закладів зі спеціальною та інклюзивною формами навчання, фахівців навчально-реабілітаційних центрів, які обізнані зі специфікою психофізичного розвитку та особливими освітніми потребами молодших глухих школярів.The program for the development of auditory-tactile perception Zoro-forming pronunciation movlennyata aimed at creating and improving skills and auditory-tactile perception Zoro-speech pronunciation and forming in individual lessons with deaf younger students.The program singled out areas of educational activities during lessons aimed at: the development of auditory-tactile perception, Zoro, development sluhozorovoyi attention and memory formation pronunciation, coordination and mobility, sensory integration own primary school children with reduced hearing. This is achieved by using a series of specific exercises and tasks

Live Prefetching for Mobile Computation Offloading

The conventional designs of mobile computation offloading fetch user-specific data to the cloud prior to computing, called offline prefetching. However, this approach can potentially result in excessive fetching of large volumes of data and cause heavy loads on radio-access networks. To solve this problem, the novel technique of live prefetching is proposed in this paper that seamlessly integrates the task-level computation prediction and prefetching within the cloud-computing process of a large program with numerous tasks. The technique avoids excessive fetching but retains the feature of leveraging prediction to reduce the program runtime and mobile transmission energy. By modeling the tasks in an offloaded program as a stochastic sequence, stochastic optimization is applied to design fetching policies to minimize mobile energy consumption under a deadline constraint. The policies enable real-time control of the prefetched-data sizes of candidates for future tasks. For slow fading, the optimal policy is derived and shown to have a threshold-based structure, selecting candidate tasks for prefetching and controlling their prefetched data based on their likelihoods. The result is extended to design close-to-optimal prefetching policies to fast fading channels. Compared with fetching without prediction, live prefetching is shown theoretically to always achieve reduction on mobile energy consumption.Comment: To appear in IEEE Trans. on Wireless Communicatio

Using the Medication Cabinet to Predict Fall Risk In Elderly Adults

Background: In the United States, 30-60% of older adults fall each year; 10-20% of these falls result in injury, hospitalization, or even death. Better prevention of falls in this population may be facilitated by broader identification of risk factors. The use of statins has emerged as a potential risk factor, but the data provide conflicted results. Purpose: To examine the relationship between statin use and falls among community-dwelling older adults. Methods: We evaluated the patient registry of a Level 1 trauma center. All patients aged \u3e 50 years who were admitted for falls in 2015 were included (n=615). Many of these patients had been previously admitted for falls and many were later readmitted for falls. We analyzed predictors of both prior admission and readmission with linear regressions. Independent variables were self-reported balance problems, diagnosis of dementia, and the use of statins. Results: On average, patients admitted for falls were 79.9 + 9.3 years old and 28% (n=173) were taking statins. Our collection of predictors explained 14.2% of the variance in the number of prior admissions (p\u3c0.001). In this model, the use of statins significantly predicted the number of previous fall-related admissions (95% CI: 0.07–0.50, p=0.010). This same model maintained its significance when predicting admissions for future falls (p\u3c0.001) and the use of statins continued to predict a greater number of readmissions (95% CI: 0.04–0.36, p=0.015). Conclusion: More than 25% of all Americans age \u3e 40 years are taking cholesterol-lowering medication; 93% of those medications are statins. Although evidence is conflicted, these data support the finding that statin therapy increases the risk of falls in older adults. Incorporating exercise training as a prophylactic measure: enhancing lipid profiles and decreasing the need for statins while also improving balance, coordination, and mobility, may reduce fall-related injuries

Determinants of university participation in EU R & D cooperative projects

Abstract not availableresearch and development ;

Impacts of Mobility Management and Human Service Transportation Coordination Efforts and End-User Quality of Life

This study developed an evaluation method to examine the effectiveness of mobility management and coordination programs in a community. A series of surveys were conducted of both transit users and stakeholders in communities across the country. Results from these surveys suggest improvements have occurred in efficiencies, ease of access, and quality of service. Most respondents to the stakeholder survey reported benefits that have been realized. Results from an ordered probit model demonstrate the positive impacts that improved mobility has on life satisfaction