178 research outputs found

    Ontologies for increasing the FAIRness of plant research data

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    The importance of improving the FAIRness (findability, accessibility, interoperability, reusability) of research data is undeniable, especially in the face of large, complex datasets currently being produced by omics technologies. Facilitating the integration of a dataset with other types of data increases the likelihood of reuse, and the potential of answering novel research questions. Ontologies are a useful tool for semantically tagging datasets as adding relevant metadata increases the understanding of how data was produced and increases its interoperability. Ontologies provide concepts for a particular domain as well as the relationships between concepts. By tagging data with ontology terms, data becomes both human and machine interpretable, allowing for increased reuse and interoperability. However, the task of identifying ontologies relevant to a particular research domain or technology is challenging, especially within the diverse realm of fundamental plant research. In this review, we outline the ontologies most relevant to the fundamental plant sciences and how they can be used to annotate data related to plant-specific experiments within metadata frameworks, such as Investigation-Study-Assay (ISA). We also outline repositories and platforms most useful for identifying applicable ontologies or finding ontology terms.Comment: 34 pages, 4 figures, 1 table, 1 supplementary tabl

    AgroPortal: a vocabulary and ontology repository for agronomy

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    Many vocabularies and ontologies are produced to represent and annotate agronomic data. However, those ontologies are spread out, in different formats, of different size, with different structures and from overlapping domains. Therefore, there is need for a common platform to receive and host them, align them, and enabling their use in agro-informatics applications. By reusing the National Center for Biomedical Ontologies (NCBO) BioPortal technology, we have designed AgroPortal, an ontology repository for the agronomy domain. The AgroPortal project re-uses the biomedical domain’s semantic tools and insights to serve agronomy, but also food, plant, and biodiversity sciences. We offer a portal that features ontology hosting, search, versioning, visualization, comment, and recommendation; enables semantic annotation; stores and exploits ontology alignments; and enables interoperation with the semantic web. The AgroPortal specifically satisfies requirements of the agronomy community in terms of ontology formats (e.g., SKOS vocabularies and trait dictionaries) and supported features (offering detailed metadata and advanced annotation capabilities). In this paper, we present our platform’s content and features, including the additions to the original technology, as well as preliminary outputs of five driving agronomic use cases that participated in the design and orientation of the project to anchor it in the community. By building on the experience and existing technology acquired from the biomedical domain, we can present in AgroPortal a robust and feature-rich repository of great value for the agronomic domain. Keyword

    Ontology Repositories and Semantic Artefact Catalogues with the OntoPortal Technology

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    Il y a une explosion dans le nombre d’ontologies et d’artefacts sémantiques. Cet article traite de la nécessité pour les plateformes communes de recevoir, héberger, servir, aligner et activer leur réutilisation. Les catalogues sont nécessaires pour répondre à ce besoin et faire des ontologies FAIR (Findable, Accessible, interopérable et réutilisable)

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    Harnessing the power of unified metadata in an ontology repository: The case of AgroPortal

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    As any resources, ontologies, thesaurus, vocabularies and terminologies need to be described with relevant metadata to facilitate their identification, selection and reuse. For ontologies to be FAIR, there is a need for metadata authoring guidelines and for harmonization of existing metadata vocabularies—taken independently none of them can completely describe an ontology. Ontology libraries and repositories also have to play an important role. Indeed, some metadata properties are intrinsic to the ontology (name, license, description); other information, such as community feedbacks or relations to other ontologies are typically information that an ontology library shall capture, populate and consolidate to facilitate the processes of identifying and selecting the right ontology(ies) to use. We have studied ontology metadata practices by: (1) analyzing metadata annotations of 805 ontologies; (2) reviewing the most standard and relevant vocabularies (23 totals) currently available to describe metadata for ontologies (such as Dublin Core, Ontology Metadata Vocabulary, VoID, etc.); (3) comparing different metadata implementation in multiple ontology libraries or repositories. We have then built a new metadata model for our AgroPortal vocabulary and ontology repository, a platform dedicated to agronomy based on the NCBO BioPortal technology. AgroPortal now recognizes 346 properties from existing metadata vocabularies that could be used to describe different aspects of ontologies: intrinsic descriptions, people, date, relations, content, metrics, community, administration, and access. We use them to populate an internal model of 127 properties implemented in the portal and harmonized for all the ontologies. We—and AgroPortal's users—have spent a significant amount of time to edit and curate the metadata of the ontologies to offer a better synthetized and harmonized information and enable new ontology identification features. Our goal was also to facilitate the comprehension of the agronomical ontology landscape by displaying diagrams and charts about all the ontologies on the portal. We have evaluated our work with a user appreciation survey which confirms the new features are indeed relevant and helpful to ease the processes of identification and selection of ontologies. This paper presents how to harness the potential of a complete and unified metadata model with dedicated features in an ontology repository; however, the new AgroPortal's model is not a new vocabulary as it relies on preexisting ones. A generalization of this work is studied in a community-driven standardization effort in the context of the RDA Vocabulary and Semantic Services Interest Group

    A machine learning taxonomic classifier for science publications

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    Dissertação de mestrado integrado em Engineering and Management of Information SystemsThe evolution in scientific production, associated with the growing interdomain collaboration of knowledge and the increasing co-authorship of scientific works remains supported by processes of manual, highly subjective classification, subject to misinterpretation. The very taxonomy on which this same classification process is based is not consensual, with governmental organizations resorting to taxonomies that do not keep up with changes in scientific areas, and indexers / repositories that seek to keep up with those changes. We find a reality distinct from what is expected and that the domains where scientific work is recorded can easily be misrepresentative of the work itself. The taxonomy applied today by governmental bodies, such as the one that regulates scientific production in Portugal, is not enough, is limiting, and promotes classification in areas close to the desired, therefore with great potential for error. An automatic classification process based on machine learning algorithms presents itself as a possible solution to the subjectivity problem in classification, and while it does not solve the issue of taxonomy mismatch this work shows this possibility with proved results. In this work, we propose a classification taxonomy, as well as we develop a process based on machine learning algorithms to solve the classification problem. We also present a set of directions for future work for an increasingly representative classification of evolution in science, which is not intended as airtight, but flexible and perhaps increasingly based on phenomena and not just disciplines.A evolução na produção de ciência, associada à crescente colaboração interdomínios do conhecimento e à também crescente coautoria de trabalhos permanece suportada por processos de classificação manual, subjetiva e sujeita a interpretações erradas. A própria taxonomia na qual assenta esse mesmo processo de classificação não é consensual, com organismos estatais a recorrerem a taxonomias que não acompanham as alterações nas áreas científicas, e indexadores/repositórios que procuram acompanhar essas mesmas alterações. Verificamos uma realidade distinta do espectável e que os domínios onde são registados os trabalhos científicos podem facilmente estar desenquadrados. A taxonomia hoje aplicada pelos organismos governamentais, como o caso do organismo que regulamenta a produção científica em Portugal, não é suficiente, é limitadora, e promove a classificação em domínios aproximados do desejado, logo com grande potencial para erro. Um processo de classificação automática com base em algoritmos de machine learning apresenta-se como uma possível solução para o problema da subjetividade na classificação, e embora não resolva a questão do desenquadramento da taxonomia utilizada, é apresentada neste trabalho como uma possibilidade comprovada. Neste trabalho propomos uma taxonomia de classificação, bem como nós desenvolvemos um processo baseado em machine learning algoritmos para resolver o problema de classificação. Apresentamos ainda um conjunto de direções para trabalhos futuros para uma classificação cada vez mais representativa da evolução nas ciências, que não pretende ser hermética, mas flexível e talvez cada vez mais baseada em fenómenos e não apenas em disciplinas

    AgBioData consortium recommendations for sustainable genomics and genetics databases for agriculture

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    The future of agricultural research depends on data. The sheer volume of agricultural biological data being produced today makes excellent data management essential. Governmental agencies, publishers and science funders require data management plans for publicly funded research. Furthermore, the value of data increases exponentially when they are properly stored, described, integrated and shared, so that they can be easily utilized in future analyses. AgBioData (https://www.agbiodata.org) is a consortium of people working at agricultural biological databases, data archives and knowledgbases who strive to identify common issues in database development, curation and management, with the goal of creating database products that are more Findable, Accessible, Interoperable and Reusable. We strive to promote authentic, detailed, accurate and explicit communication between all parties involved in scientific data. As a step toward this goal, we present the current state of biocuration, ontologies, metadata and persistence, database platforms, programmatic (machine) access to data, communication and sustainability with regard to data curation. Each section describes challenges and opportunities for these topics, along with recommendations and best practices

    Ontology Repositories and Semantic Artefact Catalogues with the OntoPortal Technology

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    Dans tous les domaines de la science, de nombreuses ontologies (ou plus largement des artefacts sémantiques 1 ) sont utilisées pour représenter et annoter les données de manière standardisée. Les artefacts sémantiques sont devenus un élément maître pour atteindre les principes FAIR en matière de données

    Proteomics of Plant Pathogenic Fungi

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    Plant pathogenic fungi cause important yield losses in crops. In order to develop efficient and environmental friendly crop protection strategies, molecular studies of the fungal biological cycle, virulence factors, and interaction with its host are necessary. For that reason, several approaches have been performed using both classical genetic, cell biology, and biochemistry and the modern, holistic, and high-throughput, omic techniques. This work briefly overviews the tools available for studying Plant Pathogenic Fungi and is amply focused on MS-based Proteomics analysis, based on original papers published up to December 2009. At a methodological level, different steps in a proteomic workflow experiment are discussed. Separate sections are devoted to fungal descriptive (intracellular, subcellular, extracellular) and differential expression proteomics and interactomics. From the work published we can conclude that Proteomics, in combination with other techniques, constitutes a powerful tool for providing important information about pathogenicity and virulence factors, thus opening up new possibilities for crop disease diagnosis and crop protection
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