Designing problem-specific operators for solving the Cell Switch-Off problem in ultra-dense 5G networks with hybrid MOEAs

The massive deployment of base stations is one of the key pillars of the fifth generation (5G) of mobile communications. However, this network densification entails high energy consumption that must be addressed to enhance the sustainability of this industry. This work faces this problem from a multi-objective optimization perspective, in which both energy efficiency and quality of service criteria are taken into account. To do so, several newly problem-specific operators have been designed so as to engineer hybrid multi-objective evolutionary metaheuristics (MOEAs) that bring expert knowledge of the domain to the search of the algorithms. These hybrid approaches have been able to improve upon canonical versions of the algorithms, clearly showing the contributions of our approach. Furthermore, this paper tests the hypothesis that the hybridization using several of those problem-specific operators simultaneously can enhance the search of MOEAs that are endowed only with a single one.Spanish Ministry of Science and Innovation via grant PID2020-112545RB-C54European Union NextGenerationEU/PRTR under grants TED2021-131699BI00TED2021-129938B-I00 (MCIN/AEI/10.13039/501100011033, FEDER)Andalusian PAIDI program with grants A-TIC-608- UGR20, P18.RT.4830PYC20-RE-012-UGRSupercomputing and Bioinformatics Center of the Universidad de MálagaUniversidad de Málaga/CBU

Designing problem-specific operators for solving the Cell Switch-Off problem in ultra-dense 5G networks with hybrid MOEAs

The massive deployment of base stations is one of the key pillars of the fifth generation (5G) of mobile communications. However, this network densification entails high energy consumption that must be addressed to enhance the sustainability of this industry. This work faces this problem from a multi-objective optimization perspective, in which both energy efficiency and quality of service criteria are taken into account. To do so, several newly problem-specific operators have been designed so as to engineer hybrid multi-objective evolutionary metaheuristics (MOEAs) that bring expert knowledge of the domain to the search of the algorithms. These hybrid approaches have been able to improve upon canonical versions of the algorithms, clearly showing the contributions of our approach. Furthermore, this paper tests the hypothesis that the hybridization using several of those problem-specific operators simultaneously can enhance the search of MOEAs that are endowed only with a single one.Funding for open access charge: Universidad de Málaga / CBUA This work has been partially funded by the Spanish Ministry of Science and Innovation via grant PID2020-112545RB-C54, by the European Union NextGenerationEU/PRTR under grants TED2021-131699B-I00 and TED2021-129938B-I00 (MCIN/AEI/10.13039/501100011033, FEDER) and the Andalusian PAIDI program with grants A-TIC-608-UGR20, P18.RT.4830, and PYC20-RE-012-UGR. The authors also thank the Supercomputing and Bioinformatics Center of the Universidad de Málaga, for providing its services and the Picasso supercomputer facilities to perform the experiments (http://www.scbi.uma.es/). Funding for open access charge: Universidad de Málaga/CBUA

Computer modeling and signal analysis of cardiovascular physiology

This dissertation aims to study cardiovascular physiology from the cellular level to the whole heart level to the body level using numerical approaches. A mathematical model was developed to describe electromechanical interaction in the heart. The model integrates cardio-electrophysiology and cardiac mechanics through excitation-induced contraction and deformation-induced currents. A finite element based parallel simulation scheme was developed to investigate coupled electrical and mechanical functions. The developed model and numerical scheme were utilized to study cardiovascular dynamics at cellular, tissue and organ levels. The influence of ion channel blockade on cardiac alternans was investigated. It was found that the channel blocker may significantly change the critical pacing period corresponding to the onset of alternans as well as the alternans’ amplitude. The influence of electro-mechanical coupling on cardiac alternans was also investigated. The study supported the earlier assumptions that discordant alternans is induced by the interaction of conduction velocity and action potential duration restitution at high pacing rates. However, mechanical contraction may influence the spatial pattern and onset of discordant alternans. Computer algorithms were developed for analysis of human physiology. The 12-lead electrocardiography (ECG) is the gold standard for diagnosis of various cardiac abnormalities. However, disturbances and mistakes may modify physiological waves in ECG and lead to wrong diagnoses. This dissertation developed advanced signal analysis techniques and computer software to detect and suppress artifacts and errors in ECG. These algorithms can help to improve the quality of health care when integrated into medical devices or services. Moreover, computer algorithms were developed to predict patient mortality in intensive care units using various physiological measures. Models and analysis techniques developed here may help to improve the quality of health care

Energy Efficiency Optimization in Green Wireless Communications

The rising energy concern and the ubiquity of energy-consuming wireless applications have sparked a keen interest in the development and deployment of energy-efficient and eco-friendly wireless communication technology. Green Wireless Communications aims to find innovative solutions to improve energy efficiency, and to relieve/reduce the carbon footprint of wireless industry, while maintaining/improving performance metrics. Looking back at the wireless communications of the past decades, the air-interface design and network deployment had mainly focused on the spectral efficiency, instead of energy efficiency. From the cellular network to the personal area network, no matter what size the wireless network is, the milestones along the evolutions of wireless networks had always been higher-and-higher data rates throughout these years. Most of these throughput-oriented optimizations lead to a full-power operation to support a higher throughput or spectral efficiency, which is typically not energy-efficient. To qualify as green wireless communications, we believe that a candidate technology needs to be of high energy efficiency, reduced electromagnetic pollution, and low-complexity. In this dissertation research, towards the evolution of the green wireless communications, we have extended our efforts in two important aspects of the wireless communications system: air-interface and networking. In the first aspect of this work, we study a promising green communications technology, the time reversal system, as a novel air-interface of the future green wireless communications. We propose a concept of time reversal division multiple access (TRDMA) as a novel wireless media access scheme for wireless broadband networks, and investigate its fundamental theoretical limits. Motivated by the great energy-harvesting potential of the TRDMA, we develop an asymmetric architecture for the TRDMA based multiuser networks. The unique asymmetric architecture shifts the most complexity to the BS in both downlink and uplink schemes, facilitating very low-cost terminal users in the networks. To further enhance the system performance, a 2D parallel interference cancellation scheme is presented to explore the inherent structure of the interference signals, and therefore efficiently improve the resulting SINR and system performance. In the second aspect of this work, we explore the energy-saving potential of the cooperative networking for cellular systems. We propose a dynamic base-station switching strategy and incorporate the cooperative base-station operation to improve the energy-efficiency of the cellular networks without sacrificing the quality of service of the users. It is shown that significant energy saving potential can be achieved by the proposed scheme

Turbulence accelerates the growth of drinking water biofilms

Biofilms are found at the inner surfaces of drinking water pipes and, therefore, it is essential to understand biofilm processes to control their formation. Hydrodynamics play a crucial role in shaping biofilms. Thus, knowing how biofilms form, develop and disperse under different flow conditions is critical in the successful management of these systems. Here, the development of biofilms after 4 weeks, the initial formation of biofilms within 10 h and finally, the response of already established biofilms within 24-h intervals in which the flow regime was changed, were studied using a rotating annular reactor under three different flow regimes: turbulent, transition and laminar. Using fluorescence microscopy, information about the number of microcolonies on the reactor slides, the surface area of biofilms and of extracellular polymeric substances and the biofilm structures was acquired. Gravimetric measurements were conducted to characterise the thickness and density of biofilms, and spatial statistics were used to characterise the heterogeneity and spatial correlation of biofilm structures. Contrary to the prevailing view, it was shown that turbulent flow did not correlate with a reduction in biofilms; turbulence was found to enhance both the initial formation and the development of biofilms on the accessible surfaces. Additionally, after 24-h changes of the flow regime it was indicated that biofilms responded to the quick changes of the flow regime. Overall, this work suggests that different flow conditions can cause substantial changes in biofilm morphology and growth and specifically that turbulent flow can accelerate biofilm growth in drinking water

A Machine Learning Enhanced Scheme for Intelligent Network Management

The versatile networking services bring about huge influence on daily living styles while the amount and diversity of services cause high complexity of network systems. The network scale and complexity grow with the increasing infrastructure apparatuses, networking function, networking slices, and underlying architecture evolution. The conventional way is manual administration to maintain the large and complex platform, which makes effective and insightful management troublesome. A feasible and promising scheme is to extract insightful information from largely produced network data. The goal of this thesis is to use learning-based algorithms inspired by machine learning communities to discover valuable knowledge from substantial network data, which directly promotes intelligent management and maintenance. In the thesis, the management and maintenance focus on two schemes: network anomalies detection and root causes localization; critical traffic resource control and optimization. Firstly, the abundant network data wrap up informative messages but its heterogeneity and perplexity make diagnosis challenging. For unstructured logs, abstract and formatted log templates are extracted to regulate log records. An in-depth analysis framework based on heterogeneous data is proposed in order to detect the occurrence of faults and anomalies. It employs representation learning methods to map unstructured data into numerical features, and fuses the extracted feature for network anomaly and fault detection. The representation learning makes use of word2vec-based embedding technologies for semantic expression. Next, the fault and anomaly detection solely unveils the occurrence of events while failing to figure out the root causes for useful administration so that the fault localization opens a gate to narrow down the source of systematic anomalies. The extracted features are formed as the anomaly degree coupled with an importance ranking method to highlight the locations of anomalies in network systems. Two types of ranking modes are instantiated by PageRank and operation errors for jointly highlighting latent issue of locations. Besides the fault and anomaly detection, network traffic engineering deals with network communication and computation resource to optimize data traffic transferring efficiency. Especially when network traffic are constrained with communication conditions, a pro-active path planning scheme is helpful for efficient traffic controlling actions. Then a learning-based traffic planning algorithm is proposed based on sequence-to-sequence model to discover hidden reasonable paths from abundant traffic history data over the Software Defined Network architecture. Finally, traffic engineering merely based on empirical data is likely to result in stale and sub-optimal solutions, even ending up with worse situations. A resilient mechanism is required to adapt network flows based on context into a dynamic environment. Thus, a reinforcement learning-based scheme is put forward for dynamic data forwarding considering network resource status, which explicitly presents a promising performance improvement. In the end, the proposed anomaly processing framework strengthens the analysis and diagnosis for network system administrators through synthesized fault detection and root cause localization. The learning-based traffic engineering stimulates networking flow management via experienced data and further shows a promising direction of flexible traffic adjustment for ever-changing environments

Network Optimisation for Robotic Aerial Base Stations

One attractive application of unmanned aerial vehicles (UAVs) is to provide wireless coverage when acting as aerial base stations (ABSs). Compared to terrestrial small cells, ABSs have the benefit of flexible deployment, controllable mobility, and dominant line-of-sight channels, so they are expected to play a significant role in next-generation cellular networks. However, introducing this novel non-terrestrial communication device would also bring new challenges, such as requiring different evaluation criteria and being restricted by unexpected resource constraints. With this in mind, this thesis mainly focuses on the network optimisation problems of ABS-assisted networks.Specifically, we first investigate two contradictory metrics, i.e., the information freshness and energy consumption, when an ABS is employed to collect data from ground terminals. A novel multi-return-allowed serving mode is proposed to explore the Pareto optimal trade-off between these two metrics. Secondly, to overcome the functional endurance issue of conventional ABSs, we propose a novel prototype named robotic aerial base stations (RABSs) with grasping capabilities, which can attach autonomously in lampposts or land on other tall urban landforms to serve as small cells with prolonged endurance. By employing this novel ABS prototype, we first study the optimal deployment and operation strategy for RABSs when the mobile traffic demand shows heterogeneity in both spatial and temporal domains. Afterwards, to further explore the use of RABSs in the upcoming 6G era, we investigate two novel application scenarios, that is, an RABS-assisted integrated sensing and communication (ISAC) system and an RABS-aided millimetre-wave (mmWave) backhaul network.The proposed scenarios are formulated as various non-convex problems. By analyzing their constructions, we propose a variety of algorithms to solve them in a reasonable time. A wide set of simulation results shows that the proposed novel prototypes and serving schemes have immense potential in future cellular networks.<br/

FROM WIDE- TO SHORT-RANGE COMMUNICATIONS: USING HUMAN INTERACTIONS TO DESIGN NEW MOBILE SYSTEMS AND SERVICES

The widespread diffusion of mobile devices has radically changed the way people interact with each other and with object of their daily life. In particular, modern mobile devices are equipped with multiple radio interfaces allowing users to interact at different spatial granularities according to the various radio technology they use. The research community is progressively moving to heterogeneous network solutions which include many different wireless technologies seamlessly integrated to address a wide variety of use cases and requirements. In 5th- Generation (5G) of mobile network we can find multiple network typology such as device-to-device (D2D), vehicular networks, machine-to-machine(M2M), and more, which are integrated in the existing mobile-broadband technology such as LTE and its future evolutions. In this complex and rich scenario, many issues and challenges are still open from a technological, architectural, and mobile services and applications points of view. In this work we provide network solutions, mobile services, and applications consistent with the 5G mobile network vision by using users interactions as a common starting point. We focus on three different spatial granularities, long, medium/short, and micro mediated by cellular network, Wi-Fi, and NFC radio technologies, respectively. We deal with various kinds of issues and challenges according to the distinct spatial granularity we consider. We start with an user centric approach based on the analysis of the characteristics and the peculiarities of each kind of interaction. Following this path, we provide contributions to support the design of new network architectures, and the development of novel mobile services and applications

Regular mosaic pattern development: A study of the interplay between lateral inhibition, apoptosis and differential adhesion

<p>Abstract</p> <p>Background</p> <p>A significant body of literature is devoted to modeling developmental mechanisms that create patterns within groups of initially equivalent embryonic cells. Although it is clear that these mechanisms do not function in isolation, the timing of and interactions between these mechanisms during embryogenesis is not well known. In this work, a computational approach was taken to understand how lateral inhibition, differential adhesion and programmed cell death can interact to create a mosaic pattern of biologically realistic primary and secondary cells, such as that formed by sensory (primary) and supporting (secondary) cells of the developing chick inner ear epithelium.</p> <p>Results</p> <p>Four different models that interlaced cellular patterning mechanisms in a variety of ways were examined and their output compared to the mosaic of sensory and supporting cells that develops in the chick inner ear sensory epithelium. The results show that: 1) no single patterning mechanism can create a 2-dimensional mosaic pattern of the regularity seen in the chick inner ear; 2) cell death was essential to generate the most regular mosaics, even through extensive cell death has not been reported for the developing basilar papilla; 3) a model that includes an iterative loop of lateral inhibition, programmed cell death and cell rearrangements driven by differential adhesion created mosaics of primary and secondary cells that are more regular than the basilar papilla; 4) this same model was much more robust to changes in homo- and heterotypic cell-cell adhesive differences than models that considered either fewer patterning mechanisms or single rather than iterative use of each mechanism.</p> <p>Conclusion</p> <p>Patterning the embryo requires collaboration between multiple mechanisms that operate iteratively. Interlacing these mechanisms into feedback loops not only refines the output patterns, but also increases the robustness of patterning to varying initial cell states.</p