Modeling of thermally induced skew variations in clock distribution network

Clock distribution network is sensitive to large thermal gradients on the die as the performance of both clock buffers and interconnects are affected by temperature. A robust clock network design relies on the accurate analysis of clock skew subject to temperature variations. In this work, we address the problem of thermally induced clock skew modeling in nanometer CMOS technologies. The complex thermal behavior of both buffers and interconnects are taken into account. In addition, our characterization of the temperature effect on buffers and interconnects provides valuable insight to designers about the potential impact of thermal variations on clock networks. The use of industrial standard data format in the interface allows our tool to be easily integrated into existing design flow

Low-power CMOS digital-pixel Imagers for high-speed uncooled PbSe IR applications

This PhD dissertation describes the research and development of a new low-cost medium wavelength infrared MWIR monolithic imager technology for high-speed uncooled industrial applications. It takes the baton on the latest technological advances in the field of vapour phase deposition (VPD) PbSe-based medium wavelength IR (MWIR) detection accomplished by the industrial partner NIT S.L., adding fundamental knowledge on the investigation of novel VLSI analog and mixed-signal design techniques at circuit and system levels for the development of the readout integrated device attached to the detector. The work supports on the hypothesis that, by the use of the preceding design techniques, current standard inexpensive CMOS technologies fulfill all operational requirements of the VPD PbSe detector in terms of connectivity, reliability, functionality and scalability to integrate the device. The resulting monolithic PbSe-CMOS camera must consume very low power, operate at kHz frequencies, exhibit good uniformity and fit the CMOS read-out active pixels in the compact pitch of the focal plane, all while addressing the particular characteristics of the MWIR detector: high dark-to-signal ratios, large input parasitic capacitance values and remarkable mismatching in PbSe integration. In order to achieve these demands, this thesis proposes null inter-pixel crosstalk vision sensor architectures based on a digital-only focal plane array (FPA) of configurable pixel sensors. Each digital pixel sensor (DPS) cell is equipped with fast communication modules, self-biasing, offset cancellation, analog-to-digital converter (ADC) and fixed pattern noise (FPN) correction. In-pixel power consumption is minimized by the use of comprehensive MOSFET subthreshold operation. The main aim is to potentiate the integration of PbSe-based infra-red (IR)-image sensing technologies so as to widen its use, not only in distinct scenarios, but also at different stages of PbSe-CMOS integration maturity. For this purpose, we posit to investigate a comprehensive set of functional blocks distributed in two parallel approaches: • Frame-based “Smart” MWIR imaging based on new DPS circuit topologies with gain and offset FPN correction capabilities. This research line exploits the detector pitch to offer fully-digital programmability at pixel level and complete functionality with input parasitic capacitance compensation and internal frame memory. • Frame-free “Compact”-pitch MWIR vision based on a novel DPS lossless analog integrator and configurable temporal difference, combined with asynchronous communication protocols inside the focal plane. This strategy is conceived to allow extensive pitch compaction and readout speed increase by the suppression of in-pixel digital filtering, and the use of dynamic bandwidth allocation in each pixel of the FPA. In order make the electrical validation of first prototypes independent of the expensive PbSe deposition processes at wafer level, investigation is extended as well to the development of affordable sensor emulation strategies and integrated test platforms specifically oriented to image read-out integrated circuits. DPS cells, imagers and test chips have been fabricated and characterized in standard 0.15μm 1P6M, 0.35μm 2P4M and 2.5μm 2P1M CMOS technologies, all as part of research projects with industrial partnership. The research has led to the first high-speed uncooled frame-based IR quantum imager monolithically fabricated in a standard VLSI CMOS technology, and has given rise to the Tachyon series [1], a new line of commercial IR cameras used in real-time industrial, environmental and transportation control systems. The frame-free architectures investigated in this work represent a firm step forward to push further pixel pitch and system bandwidth up to the limits imposed by the evolving PbSe detector in future generations of the device.La present tesi doctoral descriu la recerca i el desenvolupament d'una nova tecnologia monolítica d'imatgeria infraroja de longitud d'ona mitja (MWIR), no refrigerada i de baix cost, per a usos industrials d'alta velocitat. El treball pren el relleu dels últims avenços assolits pel soci industrial NIT S.L. en el camp dels detectors MWIR de PbSe depositats en fase vapor (VPD), afegint-hi coneixement fonamental en la investigació de noves tècniques de disseny de circuits VLSI analògics i mixtes pel desenvolupament del dispositiu integrat de lectura unit al detector pixelat. Es parteix de la hipòtesi que, mitjançant l'ús de les esmentades tècniques de disseny, les tecnologies CMOS estàndard satisfan tots els requeriments operacionals del detector VPD PbSe respecte a connectivitat, fiabilitat, funcionalitat i escalabilitat per integrar de forma econòmica el dispositiu. La càmera PbSe-CMOS resultant ha de consumir molt baixa potència, operar a freqüències de kHz, exhibir bona uniformitat, i encabir els píxels actius CMOS de lectura en el pitch compacte del pla focal de la imatge, tot atenent a les particulars característiques del detector: altes relacions de corrent d'obscuritat a senyal, elevats valors de capacitat paràsita a l'entrada i dispersions importants en el procés de fabricació. Amb la finalitat de complir amb els requisits previs, es proposen arquitectures de sensors de visió de molt baix acoblament interpíxel basades en l'ús d'una matriu de pla focal (FPA) de píxels actius exclusivament digitals. Cada píxel sensor digital (DPS) està equipat amb mòduls de comunicació d'alta velocitat, autopolarització, cancel·lació de l'offset, conversió analògica-digital (ADC) i correcció del soroll de patró fixe (FPN). El consum en cada cel·la es minimitza fent un ús exhaustiu del MOSFET operant en subllindar. L'objectiu últim és potenciar la integració de les tecnologies de sensat d'imatge infraroja (IR) basades en PbSe per expandir-ne el seu ús, no només a diferents escenaris, sinó també en diferents estadis de maduresa de la integració PbSe-CMOS. En aquest sentit, es proposa investigar un conjunt complet de blocs funcionals distribuïts en dos enfocs paral·lels: - Dispositius d'imatgeria MWIR "Smart" basats en frames utilitzant noves topologies de circuit DPS amb correcció de l'FPN en guany i offset. Aquesta línia de recerca exprimeix el pitch del detector per oferir una programabilitat completament digital a nivell de píxel i plena funcionalitat amb compensació de la capacitat paràsita d'entrada i memòria interna de fotograma. - Dispositius de visió MWIR "Compact"-pitch "frame-free" en base a un novedós esquema d'integració analògica en el DPS i diferenciació temporal configurable, combinats amb protocols de comunicació asíncrons dins del pla focal. Aquesta estratègia es concep per permetre una alta compactació del pitch i un increment de la velocitat de lectura, mitjançant la supressió del filtrat digital intern i l'assignació dinàmica de l'ample de banda a cada píxel de l'FPA. Per tal d'independitzar la validació elèctrica dels primers prototips respecte a costosos processos de deposició del PbSe sensor a nivell d'oblia, la recerca s'amplia també al desenvolupament de noves estratègies d'emulació del detector d'IR i plataformes de test integrades especialment orientades a circuits integrats de lectura d'imatge. Cel·les DPS, dispositius d'imatge i xips de test s'han fabricat i caracteritzat, respectivament, en tecnologies CMOS estàndard 0.15 micres 1P6M, 0.35 micres 2P4M i 2.5 micres 2P1M, tots dins el marc de projectes de recerca amb socis industrials. Aquest treball ha conduït a la fabricació del primer dispositiu quàntic d'imatgeria IR d'alta velocitat, no refrigerat, basat en frames, i monolíticament fabricat en tecnologia VLSI CMOS estàndard, i ha donat lloc a Tachyon, una nova línia de càmeres IR comercials emprades en sistemes de control industrial, mediambiental i de transport en temps real.Postprint (published version

The molecular basis of circadian and seasonal rhythms in the blue mussel Mytilus edulis

Exposure to regular environmental oscillations such as day/night have allowed organisms to evolve biological mechanisms to adaptively anticipate and prepare for rhythmic environmental change. A network of gene-protein interactions between clock genes and their proteins comprise the molecular clock mechanism at the heart of regulating biological rhythms. Though this is an endogenous and self-regulating system, elements of this network can be entrained by exogenous biotic and abiotic factors. This synchronisation process between environmental cycles and endogenous rhythms is facilitated by cues like light and temperature, which influence clock gene expression patterns.Marine bivalves often inhabit intertidal habitats under the influence of numerous oscillating environmental conditions, though little is known about how they regulate their biological timekeeping. In this thesis, we investigate the molecular regulation of biological rhythms in the ecologically and commercially important blue mussel, M. edulis, over different timeframes. For the first time in this species, we isolate and characterise a number of clock genes (Clk, Cry1, ROR/HR3, Per and Rev-erb) and clock-associated genes (ARNT, Timeout-like and aaNAT). Rhythmic clock gene expression is demonstrated in the absence of light cues, indicative of endogenous clock control. Differential expression of Cry1 expression between males and females under the same conditions indicates sex-specific regulation and/or function. In addition, diurnal temperature cycles modulated the otherwise rhythmic expression of Rev-erb to constant levels demonstrating an interaction of temperature with clock function. Instances of seasonal clock mRNA expression differences were found, in addition to a number of other putative seasonal genes, indicating a possible mechanism by which seasonal cues can inform rhythmic biological processes.Understanding the influence of environmental cues on the molecular clock is essential in predicting the outcomes of future environmental change on fundamental rhythmic processes, in particular the impacts of decoupled environmental cues on the already highly dynamic and stressful intertidal zone

The Barrier Properties of the Skin of Aquatic and Semi-Aquatic Vertebrates

Vertebrate skin is a heterogeneous organ that acts as a barrier to the external environment. A crucial structure for skin barrier function is the tight junction (TJ) complex that links skin epidermal cells. TJ proteins have been examined in mammalian skin but little is known about skin TJ proteins of vertebrates residing permanently or semi-permanently in water. This thesis provides new insights into the effect of abiotic and biotic factors on skin of fishes and amphibians using rainbow trout and the Australian green tree frog as models. The effects of water ion content and photoperiod on skin barrier properties and TJ proteins of trout are reported. Additionally, the effects of a deadly amphibian fungus, Batrachochytrium dendrobatidis, on skin TJ proteins of a frog are documented for the first time. This thesis provides novel information on skin TJ proteins of aquatic and semi-aquatic vertebrates and how they respond to environmental change

Variability-Aware VLSI Design Automation For Nanoscale Technologies

As technology scaling enters the nanometer regime, design of large scale ICs gets more challenging due to shrinking feature sizes and increasing design complexity. Aggressive scaling causes significant degradation in reliability, increased susceptibility to fabrication and environmental randomness and increased dynamic and leakage power dissipation. In this work, we investigate these scaling issues in large scale integrated systems. This dissertation proposes to develop variability-aware design methodologies by proposing design analysis, design-time optimization, post-silicon tunability and runtime-adaptivity based optimization techniques for handling variability. We discuss our research in the area of variability-aware analysis, specifically focusing on the problem of statistical timing analysis. The first technique presents the concept of error budgeting that achieves significant runtime speedups during statistical timing analysis. The second work presents a general framework for non-linear non-Gaussian statistical timing analysis considering correlations. Further, we present our work on design-time optimization schemes that are applicable during physical synthesis. Firstly, we present a buffer insertion technique that considers wire-length uncertainty and proposes algorithms to perform probabilistic buffer insertion. Secondly, we present a stochastic optimization framework based on Monte-Carlo technique considering fabrication variability. This optimization framework can be applied to problems that can be modeled as linear programs without without imposing any assumptions on the nature of the variability. Subsequently, we present our work on post-silicon tunability based design optimization. This work presents a design management framework that can be used to balance the effort spent on pre-silicon (through gate sizing) and post-silicon optimization (through tunable clock-tree buffers) while maximizing the yield gains. Lastly, we present our work on variability-aware runtime optimization techniques. We look at the problem of runtime supply voltage scaling for dynamic power optimization, and propose a framework to consider the impact of variability on the reliability of such designs. We propose a probabilistic design synthesis technique where reliability of the design is a primary optimization metric

Acceleration of Bayesian model based data analysis

Inverse problems for parameter estimation often face a choice between the use of a real-time scheme with strong approximations or rigorous post-processing with explicit uncertainty handling. Plasma physics experiments set a particularly high demand of both and a solution that meets all of these requirements is missing. Standard Bayesian analysis is an excellent tool for the case at hand, with the disadvantage of extensive processing times. This work therefore presents a solution that satisfies the scientific requirements while reducing the need for a speed vs. rigorosity trade-off.Die Bestimmung von Parametern bei inversen Problemen beinhaltet eine Abwägung zwischen vereinfachenden Annahmen für Echtzeitverfahren und rigoroser Datenanalyse mit Fehlerbetrachtung. Experimente in der Plasmaphysik stellen besonders hohe Anforderungen an beide, und eine Lösung, die diese Anforderungen erfüllt, fehlt. Die Bayessche Analyse ist ein exzellentes Werkzeug für diese Problemstellung, mit dem Nachteil langer Laufzeiten. Diese Arbeit stellt eine Lösung dar, die den Anforderungen entspricht und die Notwendigkeit der Abwägung zwischen Geschwindigkeit und Rigorosität reduziert

The effect of an optical network on-chip on the performance of chip multiprocessors

Optical networks on-chip (ONoC) have been proposed to reduce power consumption and increase bandwidth density in high performance chip multiprocessors (CMP), compared to electrical NoCs. However, as buffering in an ONoC is not viable, the end-to-end message path needs to be acquired in advance during which the message is buffered at the network ingress. This waiting latency is therefore a combination of path setup latency and contention and forms a significant part of the total message latency. Many proposed ONoCs, such as Single Writer, Multiple Reader (SWMR), avoid path setup latency at the expense of increased optical components. In contrast, this thesis investigates a simple circuit-switched ONoC with lower component count where nodes need to request a channel before transmission. To hide the path setup latency, a coherence-based message predictor is proposed, to setup circuits before message arrival. Firstly, the effect of latency and bandwidth on application performance is thoroughly investigated using full-system simulations of shared memory CMPs. It is shown that the latency of an ideal NoC affects the CMP performance more than the NoC bandwidth. Increasing the number of wavelengths per channel decreases the serialisation latency and improves the performance of both ONoC types. With 2 or more wavelengths modulating at 25 Gbit=s , the ONoCs will outperform a conventional electrical mesh (maximal speedup of 20%). The SWMR ONoC outperforms the circuit-switched ONoC. Next coherence-based prediction techniques are proposed to reduce the waiting latency. The ideal coherence-based predictor reduces the waiting latency by 42%. A more streamlined predictor (smaller than a L1 cache) reduces the waiting latency by 31%. Without prediction, the message latency in the circuit-switched ONoC is 11% larger than in the SWMR ONoC. Applying the realistic predictor reverses this: the message latency in the SWMR ONoC is now 18% larger than the predictive circuitswitched ONoC

Proceedings of the 5th International Workshop on Reconfigurable Communication-centric Systems on Chip 2010 - ReCoSoC\u2710 - May 17-19, 2010 Karlsruhe, Germany. (KIT Scientific Reports ; 7551)

ReCoSoC is intended to be a periodic annual meeting to expose and discuss gathered expertise as well as state of the art research around SoC related topics through plenary invited papers and posters. The workshop aims to provide a prospective view of tomorrow\u27s challenges in the multibillion transistor era, taking into account the emerging techniques and architectures exploring the synergy between flexible on-chip communication and system reconfigurability