Individual differences in human path integration abilities correlate with gray matter volume in retrosplenial cortex, hippocampus, and medial prefrontal cortex

Humans differ in their individual navigational abilities. These individual differences may exist in part because successful navigation relies on several disparate abilities, which rely on different brain structures. One such navigational capability is path integration, the updating of position and orientation, in which navigators track distances, directions, and locations in space during movement. Although structural differences related to landmark-based navigation have been examined, gray matter volume related to path integration ability has not yet been tested. Here, we examined individual differences in two path integration paradigms: (1) a location tracking task and (2) a task tracking translational and rotational self-motion. Using voxel-based morphometry, we related differences in performance in these path integration tasks to variation in brain morphology in 26 healthy young adults. Performance in the location tracking task positively correlated with individual differences in gray matter volume in three areas critical for path integration: the hippocampus, the retrosplenial cortex, and the medial prefrontal cortex. These regions are consistent with the path integration system known from computational and animal models and provide novel evidence that morphological variability in retrosplenial and medial prefrontal cortices underlies individual differences in human path integration ability. The results for tracking rotational self-motion-but not translation or location-demonstrated that cerebellum gray matter volume correlated with individual performance. Our findings also suggest that these three aspects of path integration are largely independent. Together, the results of this study provide a link between individual abilities and the functional correlates, computational models, and animal models of path integration

Novel Correspondence-based Approach for Consistent Human Skeleton Extraction

This paper presents a novel base-points-driven shape correspondence (BSC) approach to extract skeletons of articulated objects from 3D mesh shapes. The skeleton extraction based on BSC approach is more accurate than the traditional direct skeleton extraction methods. Since 3D shapes provide more geometric information, BSC offers the consistent information between the source shape and the target shapes. In this paper, we first extract the skeleton from a template shape such as the source shape automatically. Then, the skeletons of the target shapes of different poses are generated based on the correspondence relationship with source shape. The accuracy of the proposed method is demonstrated by presenting a comprehensive performance evaluation on multiple benchmark datasets. The results of the proposed approach can be applied to various applications such as skeleton-driven animation, shape segmentation and human motion analysis

Automatic Landmarking for Non-cooperative 3D Face Recognition

This thesis describes a new framework for 3D surface landmarking and evaluates its performance for feature localisation on human faces. This framework has two main parts that can be designed and optimised independently. The first one is a keypoint detection system that returns positions of interest for a given mesh surface by using a learnt dictionary of local shapes. The second one is a labelling system, using model fitting approaches that establish a one-to-one correspondence between the set of unlabelled input points and a learnt representation of the class of object to detect. Our keypoint detection system returns local maxima over score maps that are generated from an arbitrarily large set of local shape descriptors. The distributions of these descriptors (scalars or histograms) are learnt for known landmark positions on a training dataset in order to generate a model. The similarity between the input descriptor value for a given vertex and a model shape is used as a descriptor-related score. Our labelling system can make use of both hypergraph matching techniques and rigid registration techniques to reduce the ambiguity attached to unlabelled input keypoints for which a list of model landmark candidates have been seeded. The soft matching techniques use multi-attributed hyperedges to reduce ambiguity, while the registration techniques use scale-adapted rigid transformation computed from 3 or more points in order to obtain one-to-one correspondences. Our final system achieves better or comparable (depending on the metric) results than the state-of-the-art while being more generic. It does not require pre-processing such as cropping, spike removal and hole filling and is more robust to occlusion of salient local regions, such as those near the nose tip and inner eye corners. It is also fully pose invariant and can be used with kinds of objects other than faces, provided that labelled training data is available

Computational processing and analysis of ear images

Tese de mestrado. Engenharia Biomédica. Faculdade de Engenharia. Universidade do Porto. 201

Development of an Atlas-Based Segmentation of Cranial Nerves Using Shape-Aware Discrete Deformable Models for Neurosurgical Planning and Simulation

Twelve pairs of cranial nerves arise from the brain or brainstem and control our sensory functions such as vision, hearing, smell and taste as well as several motor functions to the head and neck including facial expressions and eye movement. Often, these cranial nerves are difficult to detect in MRI data, and thus represent problems in neurosurgery planning and simulation, due to their thin anatomical structure, in the face of low imaging resolution as well as image artifacts. As a result, they may be at risk in neurosurgical procedures around the skull base, which might have dire consequences such as the loss of eyesight or hearing and facial paralysis. Consequently, it is of great importance to clearly delineate cranial nerves in medical images for avoidance in the planning of neurosurgical procedures and for targeting in the treatment of cranial nerve disorders. In this research, we propose to develop a digital atlas methodology that will be used to segment the cranial nerves from patient image data. The atlas will be created from high-resolution MRI data based on a discrete deformable contour model called 1-Simplex mesh. Each of the cranial nerves will be modeled using its centerline and radius information where the centerline is estimated in a semi-automatic approach by finding a shortest path between two user-defined end points. The cranial nerve atlas is then made more robust by integrating a Statistical Shape Model so that the atlas can identify and segment nerves from images characterized by artifacts or low resolution. To the best of our knowledge, no such digital atlas methodology exists for segmenting nerves cranial nerves from MRI data. Therefore, our proposed system has important benefits to the neurosurgical community

Visually Guided Control of Movement

The papers given at an intensive, three-week workshop on visually guided control of movement are presented. The participants were researchers from academia, industry, and government, with backgrounds in visual perception, control theory, and rotorcraft operations. The papers included invited lectures and preliminary reports of research initiated during the workshop. Three major topics are addressed: extraction of environmental structure from motion; perception and control of self motion; and spatial orientation. Each topic is considered from both theoretical and applied perspectives. Implications for control and display are suggested

Learning cognitive maps: Finding useful structure in an uncertain world

In this chapter we will describe the central mechanisms that influence how people learn about large-scale space. We will focus particularly on how these mechanisms enable people to effectively cope with both the uncertainty inherent in a constantly changing world and also with the high information content of natural environments. The major lessons are that humans get by with a less is more approach to building structure, and that they are able to quickly adapt to environmental changes thanks to a range of general purpose mechanisms. By looking at abstract principles, instead of concrete implementation details, it is shown that the study of human learning can provide valuable lessons for robotics. Finally, these issues are discussed in the context of an implementation on a mobile robot. © 2007 Springer-Verlag Berlin Heidelberg