Machine Learning Methods for Image Analysis in Medical Applications, from Alzheimer\u27s Disease, Brain Tumors, to Assisted Living

Healthcare has progressed greatly nowadays owing to technological advances, where machine learning plays an important role in processing and analyzing a large amount of medical data. This thesis investigates four healthcare-related issues (Alzheimer\u27s disease detection, glioma classification, human fall detection, and obstacle avoidance in prosthetic vision), where the underlying methodologies are associated with machine learning and computer vision. For Alzheimer’s disease (AD) diagnosis, apart from symptoms of patients, Magnetic Resonance Images (MRIs) also play an important role. Inspired by the success of deep learning, a new multi-stream multi-scale Convolutional Neural Network (CNN) architecture is proposed for AD detection from MRIs, where AD features are characterized in both the tissue level and the scale level for improved feature learning. Good classification performance is obtained for AD/NC (normal control) classification with test accuracy 94.74%. In glioma subtype classification, biopsies are usually needed for determining different molecular-based glioma subtypes. We investigate non-invasive glioma subtype prediction from MRIs by using deep learning. A 2D multi-stream CNN architecture is used to learn the features of gliomas from multi-modal MRIs, where the training dataset is enlarged with synthetic brain MRIs generated by pairwise Generative Adversarial Networks (GANs). Test accuracy 88.82% has been achieved for IDH mutation (a molecular-based subtype) prediction. A new deep semi-supervised learning method is also proposed to tackle the problem of missing molecular-related labels in training datasets for improving the performance of glioma classification. In other two applications, we also address video-based human fall detection by using co-saliency-enhanced Recurrent Convolutional Networks (RCNs), as well as obstacle avoidance in prosthetic vision by characterizing obstacle-related video features using a Spiking Neural Network (SNN). These investigations can benefit future research, where artificial intelligence/deep learning may open a new way for real medical applications

Proceedings of the COST Action TU1403 : Adaptive Facades Network Final Conference

info:eu-repo/semantics/publishedVersio

Data science, analytics and artificial intelligence in e-health : trends, applications and challenges

Acknowledgments. This work has been partially supported by the Divina Pastora Seguros company.More than ever, healthcare systems can use data, predictive models, and intelligent algorithms to optimize their operations and the service they provide. This paper reviews the existing literature regarding the use of data science/analytics methods and artificial intelligence algorithms in healthcare. The paper also discusses how healthcare organizations can benefit from these tools to efficiently deal with a myriad of new possibilities and strategies. Examples of real applications are discussed to illustrate the potential of these methods. Finally, the paper highlights the main challenges regarding the use of these methods in healthcare, as well as some open research lines

Natural Language Processing in Electronic Health Records in Relation to Healthcare Decision-making: A Systematic Review

Background: Natural Language Processing (NLP) is widely used to extract clinical insights from Electronic Health Records (EHRs). However, the lack of annotated data, automated tools, and other challenges hinder the full utilisation of NLP for EHRs. Various Machine Learning (ML), Deep Learning (DL) and NLP techniques are studied and compared to understand the limitations and opportunities in this space comprehensively. Methodology: After screening 261 articles from 11 databases, we included 127 papers for full-text review covering seven categories of articles: 1) medical note classification, 2) clinical entity recognition, 3) text summarisation, 4) deep learning (DL) and transfer learning architecture, 5) information extraction, 6) Medical language translation and 7) other NLP applications. This study follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Result and Discussion: EHR was the most commonly used data type among the selected articles, and the datasets were primarily unstructured. Various ML and DL methods were used, with prediction or classification being the most common application of ML or DL. The most common use cases were: the International Classification of Diseases, Ninth Revision (ICD-9) classification, clinical note analysis, and named entity recognition (NER) for clinical descriptions and research on psychiatric disorders. Conclusion: We find that the adopted ML models were not adequately assessed. In addition, the data imbalance problem is quite important, yet we must find techniques to address this underlining problem. Future studies should address key limitations in studies, primarily identifying Lupus Nephritis, Suicide Attempts, perinatal self-harmed and ICD-9 classification

Privacy-preserving human mobility and activity modelling

The exponential proliferation of digital trends and worldwide responses to the COVID-19 pandemic thrust the world into digitalization and interconnectedness, pushing increasingly new technologies/devices/applications into the market. More and more intimate data of users are collected for positive analysis purposes of improving living well-being but shared with/without the user's consent, emphasizing the importance of making human mobility and activity models inclusive, private, and fair. In this thesis, I develop and implement advanced methods/algorithms to model human mobility and activity in terms of temporal-context dynamics, multi-occupancy impacts, privacy protection, and fair analysis. The following research questions have been thoroughly investigated: i) whether the temporal information integrated into the deep learning networks can improve the prediction accuracy in both predicting the next activity and its timing; ii) how is the trade-off between cost and performance when optimizing the sensor network for multiple-occupancy smart homes; iii) whether the malicious purposes such as user re-identification in human mobility modelling could be mitigated by adversarial learning; iv) whether the fairness implications of mobility models and whether privacy-preserving techniques perform equally for different groups of users. To answer these research questions, I develop different architectures to model human activity and mobility. I first clarify the temporal-context dynamics in human activity modelling and achieve better prediction accuracy by appropriately using the temporal information. I then design a framework MoSen to simulate the interaction dynamics among residents and intelligent environments and generate an effective sensor network strategy. To relieve users' privacy concerns, I design Mo-PAE and show that the privacy of mobility traces attains decent protection at the marginal utility cost. Last but not least, I investigate the relations between fairness and privacy and conclude that while the privacy-aware model guarantees group fairness, it violates the individual fairness criteria.Open Acces

Becoming Human with Humanoid

Nowadays, our expectations of robots have been significantly increases. The robot, which was initially only doing simple jobs, is now expected to be smarter and more dynamic. People want a robot that resembles a human (humanoid) has and has emotional intelligence that can perform action-reaction interactions. This book consists of two sections. The first section focuses on emotional intelligence, while the second section discusses the control of robotics. The contents of the book reveal the outcomes of research conducted by scholars in robotics fields to accommodate needs of society and industry

Front-Line Physicians' Satisfaction with Information Systems in Hospitals

Day-to-day operations management in hospital units is difficult due to continuously varying situations, several actors involved and a vast number of information systems in use. The aim of this study was to describe front-line physicians' satisfaction with existing information systems needed to support the day-to-day operations management in hospitals. A cross-sectional survey was used and data chosen with stratified random sampling were collected in nine hospitals. Data were analyzed with descriptive and inferential statistical methods. The response rate was 65 % (n = 111). The physicians reported that information systems support their decision making to some extent, but they do not improve access to information nor are they tailored for physicians. The respondents also reported that they need to use several information systems to support decision making and that they would prefer one information system to access important information. Improved information access would better support physicians' decision making and has the potential to improve the quality of decisions and speed up the decision making process.Peer reviewe