15,988 research outputs found
Communication channel analysis and real time compressed sensing for high density neural recording devices
Next generation neural recording and Brain-
Machine Interface (BMI) devices call for high density or distributed
systems with more than 1000 recording sites. As the
recording site density grows, the device generates data on the
scale of several hundred megabits per second (Mbps). Transmitting
such large amounts of data induces significant power
consumption and heat dissipation for the implanted electronics.
Facing these constraints, efficient on-chip compression techniques
become essential to the reduction of implanted systems power
consumption. This paper analyzes the communication channel
constraints for high density neural recording devices. This paper
then quantifies the improvement on communication channel
using efficient on-chip compression methods. Finally, This paper
describes a Compressed Sensing (CS) based system that can
reduce the data rate by > 10x times while using power on
the order of a few hundred nW per recording channel
QuASeR -- Quantum Accelerated De Novo DNA Sequence Reconstruction
In this article, we present QuASeR, a reference-free DNA sequence
reconstruction implementation via de novo assembly on both gate-based and
quantum annealing platforms. Each one of the four steps of the implementation
(TSP, QUBO, Hamiltonians and QAOA) is explained with simple proof-of-concept
examples to target both the genomics research community and quantum application
developers in a self-contained manner. The details of the implementation are
discussed for the various layers of the quantum full-stack accelerator design.
We also highlight the limitations of current classical simulation and available
quantum hardware systems. The implementation is open-source and can be found on
https://github.com/prince-ph0en1x/QuASeR.Comment: 24 page
Spiking Neural Networks for Inference and Learning: A Memristor-based Design Perspective
On metrics of density and power efficiency, neuromorphic technologies have
the potential to surpass mainstream computing technologies in tasks where
real-time functionality, adaptability, and autonomy are essential. While
algorithmic advances in neuromorphic computing are proceeding successfully, the
potential of memristors to improve neuromorphic computing have not yet born
fruit, primarily because they are often used as a drop-in replacement to
conventional memory. However, interdisciplinary approaches anchored in machine
learning theory suggest that multifactor plasticity rules matching neural and
synaptic dynamics to the device capabilities can take better advantage of
memristor dynamics and its stochasticity. Furthermore, such plasticity rules
generally show much higher performance than that of classical Spike Time
Dependent Plasticity (STDP) rules. This chapter reviews the recent development
in learning with spiking neural network models and their possible
implementation with memristor-based hardware
Focused Proofreading: Efficiently Extracting Connectomes from Segmented EM Images
Identifying complex neural circuitry from electron microscopic (EM) images
may help unlock the mysteries of the brain. However, identifying this circuitry
requires time-consuming, manual tracing (proofreading) due to the size and
intricacy of these image datasets, thus limiting state-of-the-art analysis to
very small brain regions. Potential avenues to improve scalability include
automatic image segmentation and crowd sourcing, but current efforts have had
limited success. In this paper, we propose a new strategy, focused
proofreading, that works with automatic segmentation and aims to limit
proofreading to the regions of a dataset that are most impactful to the
resulting circuit. We then introduce a novel workflow, which exploits
biological information such as synapses, and apply it to a large dataset in the
fly optic lobe. With our techniques, we achieve significant tracing speedups of
3-5x without sacrificing the quality of the resulting circuit. Furthermore, our
methodology makes the task of proofreading much more accessible and hence
potentially enhances the effectiveness of crowd sourcing
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