79 research outputs found
Clinical Data Reuse or Secondary Use: Current Status and Potential Future Progress
Objective: To perform a review of recent research in clinical data reuse or secondary use, and envision future advances in this field. Methods: The review is based on a large literature search in MEDLINE (through PubMed), conference proceedings, and the ACM Digital Library, focusing only on research published between 2005 and early 2016. Each selected publication was reviewed by the authors, and a structured analysis and summarization of its content was developed. Results: The initial search produced 359 publications, reduced after a manual examination of abstracts and full publications. The following aspects of clinical data reuse are discussed: motivations and challenges, privacy and ethical concerns, data integration and interoperability, data models and terminologies, unstructured data reuse, structured data mining, clinical practice and research integration, and examples of clinical data reuse (quality measurement and learning healthcare systems). Conclusion: Reuse of clinical data is a fast-growing field recognized as essential to realize the potentials for high quality healthcare, improved healthcare management, reduced healthcare costs, population health management, and effective clinical research
Big data and diabetes: the applications of big data for diabetes care now and in the future
Aims: Review the current applications of Big Data in diabetes care and consider the future potential.
Methods: Scoping study of the academic literature on Big Data and diabetes care.
Results: Healthcare data are being produced at ever-increasing rates, and this information has the potential to transform the provision of diabetes care. Big Data is beginning to have an impact on diabetes care through data research. The use of Big Data for routine clinical care is still a future application.
Conclusions: Vast amounts of healthcare data are already being produced, and the key is harnessing these to produce actionable insights. Considerable development work is required to achieve these goals
Social analytics for health integration, intelligence, and monitoring
Nowadays, patient-generated social health data are abundant and Healthcare is changing from the authoritative provider-centric model to collaborative and patient-oriented care. The aim of this dissertation is to provide a Social Health Analytics framework to utilize social data to solve the interdisciplinary research challenges of Big Data Science and Health Informatics. Specific research issues and objectives are described below.
The first objective is semantic integration of heterogeneous health data sources, which can vary from structured to unstructured and include patient-generated social data as well as authoritative data. An information seeker has to spend time selecting information from many websites and integrating it into a coherent mental model. An integrated health data model is designed to allow accommodating data features from different sources. The model utilizes semantic linked data for lightweight integration and allows a set of analytics and inferences over data sources. A prototype analytical and reasoning tool called “Social InfoButtons” that can be linked from existing EHR systems is developed to allow doctors to understand and take into consideration the behaviors, patterns or trends of patients’ healthcare practices during a patient’s care. The tool can also shed insights for public health officials to make better-informed policy decisions.
The second objective is near-real time monitoring of disease outbreaks using social media. The research for epidemics detection based on search query terms entered by millions of users is limited by the fact that query terms are not easily accessible by non-affiliated researchers. Publically available Twitter data is exploited to develop the Epidemics Outbreak and Spread Detection System (EOSDS). EOSDS provides four visual analytics tools for monitoring epidemics, i.e., Instance Map, Distribution Map, Filter Map, and Sentiment Trend to investigate public health threats in space and time.
The third objective is to capture, analyze and quantify public health concerns through sentiment classifications on Twitter data. For traditional public health surveillance systems, it is hard to detect and monitor health related concerns and changes in public attitudes to health-related issues, due to their expenses and significant time delays. A two-step sentiment classification model is built to measure the concern. In the first step, Personal tweets are distinguished from Non-Personal tweets. In the second step, Personal Negative tweets are further separated from Personal Non-Negative tweets. In the proposed classification, training data is labeled by an emotion-oriented, clue-based method, and three Machine Learning models are trained and tested. Measure of Concern (MOC) is computed based on the number of Personal Negative sentiment tweets. A timeline trend of the MOC is also generated to monitor public concern levels, which is important for health emergency resource allocations and policy making.
The fourth objective is predicting medical condition incidence and progression trajectories by using patients’ self-reported data on PatientsLikeMe. Some medical conditions are correlated with each other to a measureable degree (“comorbidities”). A prediction model is provided to predict the comorbidities and rank future conditions by their likelihood and to predict the possible progression trajectories given an observed medical condition. The novel models for trajectory prediction of medical conditions are validated to cover the comorbidities reported in the medical literature
Social and behavioral determinants of health in the era of artificial intelligence with electronic health records: A scoping review
Background: There is growing evidence that social and behavioral determinants
of health (SBDH) play a substantial effect in a wide range of health outcomes.
Electronic health records (EHRs) have been widely employed to conduct
observational studies in the age of artificial intelligence (AI). However,
there has been little research into how to make the most of SBDH information
from EHRs. Methods: A systematic search was conducted in six databases to find
relevant peer-reviewed publications that had recently been published. Relevance
was determined by screening and evaluating the articles. Based on selected
relevant studies, a methodological analysis of AI algorithms leveraging SBDH
information in EHR data was provided. Results: Our synthesis was driven by an
analysis of SBDH categories, the relationship between SBDH and
healthcare-related statuses, and several NLP approaches for extracting SDOH
from clinical literature. Discussion: The associations between SBDH and health
outcomes are complicated and diverse; several pathways may be involved. Using
Natural Language Processing (NLP) technology to support the extraction of SBDH
and other clinical ideas simplifies the identification and extraction of
essential concepts from clinical data, efficiently unlocks unstructured data,
and aids in the resolution of unstructured data-related issues. Conclusion:
Despite known associations between SBDH and disease, SBDH factors are rarely
investigated as interventions to improve patient outcomes. Gaining knowledge
about SBDH and how SBDH data can be collected from EHRs using NLP approaches
and predictive models improves the chances of influencing health policy change
for patient wellness, and ultimately promoting health and health equity.
Keywords: Social and Behavioral Determinants of Health, Artificial
Intelligence, Electronic Health Records, Natural Language Processing,
Predictive ModelComment: 32 pages, 5 figure
System for monitoring and supporting the treatment of sleep apnea using IoT and big data
[EN] Sleep apnea has become in the sleep disorder that causes greater concern in recent years due to its morbidity and mortality, higher medical care costs and poor people quality of life. Some proposals have addressed sleep apnea disease in elderly people, but they have still some technical limitations. For these reasons, this paper presents an innovative system based on fog and cloud computing technologies which in combination with IoT and big data platforms offers new opportunities to build novel and innovative services for supporting the sleep apnea and to overcome the current limitations. Particularly, the system is built on several low-power wireless networks with heterogeneous smart devices (i.e, sensors and actuators). In the fog, an edge node (Smart IoT Gateway) provides IoT connection and interoperability and pre-processing IoT data to detect events in real-time that might endanger the elderly's health and to act accordingly. In the cloud, a Generic Enabler Context Broker manages, stores and injects data into the big data analyzer for further processing and analyzing. The system's performance and subjective applicability are evaluated using over 30 GB size datasets and a questionnaire fulfilled by medicals specialist, respectively. Results show that the system data analytics improve the health professionals' decision making to monitor and guide sleep apnea treatment, as well as improving elderly people's quality of life. (C) 2018 Elsevier B.V. All rights reserved.This research was supported by the Ecuadorian Government through the Secretary of Higher Education, Science, Technology, and Innovation (SENESCYT) and has received funding from the European Union's "Horizon 2020'' research and innovation program as part of the ACTIVAGE project under Grant 732679 and the Interoperability of Heterogeneous IoT Platforms project (INTER-IoT) under Grant 687283.Yacchirema-Vargas, DC.; Sarabia-Jácome, DF.; Palau Salvador, CE.; Esteve Domingo, M. (2018). System for monitoring and supporting the treatment of sleep apnea using IoT and big data. Pervasive and Mobile Computing. 50:25-40. https://doi.org/10.1016/j.pmcj.2018.07.007S25405
American Family Cohort, a data resource description
This manuscript is a research resource description and presents a large and
novel Electronic Health Records (EHR) data resource, American Family Cohort
(AFC). The AFC data is derived from Centers for Medicare and Medicaid Services
(CMS) certified American Board of Family Medicine (ABFM) PRIME registry. The
PRIME registry is the largest national Qualified Clinical Data Registry (QCDR)
for Primary Care. The data is converted to a popular common data model, the
Observational Health Data Sciences and Informatics (OHDSI) Observational
Medical Outcomes Partnership (OMOP) Common Data Model (CDM).
The resource presents approximately 90 million encounters for 7.5 million
patients. All 100% of the patients present age, gender, and address
information, and 73% report race. Nealy 93% of patients have lab data in LOINC,
86% have medication data in RxNorm, 93% have diagnosis in SNOWMED and ICD, 81%
have procedures in HCPCS or CPT, and 61% have insurance information. The
richness, breadth, and diversity of this research accessible and research ready
data is expected to accelerate observational studies in many diverse areas. We
expect this resource to facilitate research in many years to come
Enhancing health risk prediction with deep learning on big data and revised fusion node paradigm
With recent advances in health systems, the amount of health data is expanding rapidly in various formats. This data originates from many new sources including digital records, mobile devices, and wearable health devices. Big health data offers more opportunities for health data analysis and enhancement of health services via innovative approaches. The objective of this research is to develop a framework to enhance health prediction with the revised fusion node and deep learning paradigms. Fusion node is an information fusion model for constructing prediction systems. Deep learning involves the complex application of machine-learning algorithms, such as Bayesian fusions and neural network, for data extraction and logical inference. Deep learning, combined with information fusion paradigms, can be utilized to provide more comprehensive and reliable predictions from big health data. Based on the proposed framework, an experimental system is developed as an illustration for the framework implementatio
Front-Line Physicians' Satisfaction with Information Systems in Hospitals
Day-to-day operations management in hospital units is difficult due to continuously varying situations, several actors involved and a vast number of information systems in use. The aim of this study was to describe front-line physicians' satisfaction with existing information systems needed to support the day-to-day operations management in hospitals. A cross-sectional survey was used and data chosen with stratified random sampling were collected in nine hospitals. Data were analyzed with descriptive and inferential statistical methods. The response rate was 65 % (n = 111). The physicians reported that information systems support their decision making to some extent, but they do not improve access to information nor are they tailored for physicians. The respondents also reported that they need to use several information systems to support decision making and that they would prefer one information system to access important information. Improved information access would better support physicians' decision making and has the potential to improve the quality of decisions and speed up the decision making process.Peer reviewe
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