305 research outputs found
Prior distributions for objective Bayesian analysis
We provide a review of prior distributions for objective Bayesian analysis. We start by examining some foundational issues and then organize our exposition into priors for: i) estimation or prediction; ii) model selection; iii) highdimensional models. With regard to i), we present some basic notions, and then move to more recent contributions on discrete parameter space, hierarchical models, nonparametric models, and penalizing complexity priors. Point ii) is the focus of this paper: it discusses principles for objective Bayesian model comparison, and singles out some major concepts for building priors, which are subsequently illustrated in some detail for the classic problem of variable selection in normal linear models. We also present some recent contributions in the area of objective priors on model space.With regard to point iii) we only provide a short summary of some default priors for high-dimensional models, a rapidly growing area of research
Nonparametric Statistical Inference with an Emphasis on Information-Theoretic Methods
This book addresses contemporary statistical inference issues when no or minimal assumptions on the nature of studied phenomenon are imposed. Information theory methods play an important role in such scenarios. The approaches discussed include various high-dimensional regression problems, time series and dependence analyses
High Dimensional Classification with combined Adaptive Sparse PLS and Logistic Regression
Motivation: The high dimensionality of genomic data calls for the development
of specific classification methodologies, especially to prevent over-optimistic
predictions. This challenge can be tackled by compression and variable
selection, which combined constitute a powerful framework for classification,
as well as data visualization and interpretation. However, current proposed
combinations lead to instable and non convergent methods due to inappropriate
computational frameworks. We hereby propose a stable and convergent approach
for classification in high dimensional based on sparse Partial Least Squares
(sparse PLS). Results: We start by proposing a new solution for the sparse PLS
problem that is based on proximal operators for the case of univariate
responses. Then we develop an adaptive version of the sparse PLS for
classification, which combines iterative optimization of logistic regression
and sparse PLS to ensure convergence and stability. Our results are confirmed
on synthetic and experimental data. In particular we show how crucial
convergence and stability can be when cross-validation is involved for
calibration purposes. Using gene expression data we explore the prediction of
breast cancer relapse. We also propose a multicategorial version of our method
on the prediction of cell-types based on single-cell expression data.
Availability: Our approach is implemented in the plsgenomics R-package.Comment: 9 pages, 3 figures, 4 tables + Supplementary Materials 8 pages, 3
figures, 10 table
Innovations in Quantitative Risk Management
Quantitative Finance; Game Theory, Economics, Social and Behav. Sciences; Finance/Investment/Banking; Actuarial Science
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