Radiation therapy calculations using an on-demand virtual cluster via cloud computing

Computer hardware costs are the limiting factor in producing highly accurate radiation dose calculations on convenient time scales. Because of this, large-scale, full Monte Carlo simulations and other resource intensive algorithms are often considered infeasible for clinical settings. The emerging cloud computing paradigm promises to fundamentally alter the economics of such calculations by providing relatively cheap, on-demand, pay-as-you-go computing resources over the Internet. We believe that cloud computing will usher in a new era, in which very large scale calculations will be routinely performed by clinics and researchers using cloud-based resources. In this research, several proof-of-concept radiation therapy calculations were successfully performed on a cloud-based virtual Monte Carlo cluster. Performance evaluations were made of a distributed processing framework developed specifically for this project. The expected 1/n performance was observed with some caveats. The economics of cloud-based virtual computing clusters versus traditional in-house hardware is also discussed. For most situations, cloud computing can provide a substantial cost savings for distributed calculations.Comment: 12 pages, 4 figure

Transparent Orchestration of Task-based Parallel Applications in Containers Platforms

This paper presents a framework to easily build and execute parallel applications in container-based distributed computing platforms in a user-transparent way. The proposed framework is a combination of the COMP Superscalar (COMPSs) programming model and runtime, which provides a straightforward way to develop task-based parallel applications from sequential codes, and containers management platforms that ease the deployment of applications in computing environments (as Docker, Mesos or Singularity). This framework provides scientists and developers with an easy way to implement parallel distributed applications and deploy them in a one-click fashion. We have built a prototype which integrates COMPSs with different containers engines in different scenarios: i) a Docker cluster, ii) a Mesos cluster, and iii) Singularity in an HPC cluster. We have evaluated the overhead in the building phase, deployment and execution of two benchmark applications compared to a Cloud testbed based on KVM and OpenStack and to the usage of bare metal nodes. We have observed an important gain in comparison to cloud environments during the building and deployment phases. This enables better adaptation of resources with respect to the computational load. In contrast, we detected an extra overhead during the execution, which is mainly due to the multi-host Docker networking.This work is partly supported by the Spanish Government through Programa Severo Ochoa (SEV-2015-0493), by the Spanish Ministry of Science and Technology through TIN2015-65316 project, by the Generalitat de Catalunya under contracts 2014-SGR-1051 and 2014-SGR-1272, and by the European Union through the Horizon 2020 research and innovation program under grant 690116 (EUBra-BIGSEA Project). Results presented in this paper were obtained using the Chameleon testbed supported by the National Science Foundation.Peer ReviewedPostprint (author's final draft

Checkpointing as a Service in Heterogeneous Cloud Environments

A non-invasive, cloud-agnostic approach is demonstrated for extending existing cloud platforms to include checkpoint-restart capability. Most cloud platforms currently rely on each application to provide its own fault tolerance. A uniform mechanism within the cloud itself serves two purposes: (a) direct support for long-running jobs, which would otherwise require a custom fault-tolerant mechanism for each application; and (b) the administrative capability to manage an over-subscribed cloud by temporarily swapping out jobs when higher priority jobs arrive. An advantage of this uniform approach is that it also supports parallel and distributed computations, over both TCP and InfiniBand, thus allowing traditional HPC applications to take advantage of an existing cloud infrastructure. Additionally, an integrated health-monitoring mechanism detects when long-running jobs either fail or incur exceptionally low performance, perhaps due to resource starvation, and proactively suspends the job. The cloud-agnostic feature is demonstrated by applying the implementation to two very different cloud platforms: Snooze and OpenStack. The use of a cloud-agnostic architecture also enables, for the first time, migration of applications from one cloud platform to another.Comment: 20 pages, 11 figures, appears in CCGrid, 201

High-Performance Cloud Computing: A View of Scientific Applications

Scientific computing often requires the availability of a massive number of computers for performing large scale experiments. Traditionally, these needs have been addressed by using high-performance computing solutions and installed facilities such as clusters and super computers, which are difficult to setup, maintain, and operate. Cloud computing provides scientists with a completely new model of utilizing the computing infrastructure. Compute resources, storage resources, as well as applications, can be dynamically provisioned (and integrated within the existing infrastructure) on a pay per use basis. These resources can be released when they are no more needed. Such services are often offered within the context of a Service Level Agreement (SLA), which ensure the desired Quality of Service (QoS). Aneka, an enterprise Cloud computing solution, harnesses the power of compute resources by relying on private and public Clouds and delivers to users the desired QoS. Its flexible and service based infrastructure supports multiple programming paradigms that make Aneka address a variety of different scenarios: from finance applications to computational science. As examples of scientific computing in the Cloud, we present a preliminary case study on using Aneka for the classification of gene expression data and the execution of fMRI brain imaging workflow.Comment: 13 pages, 9 figures, conference pape

funcX: A Federated Function Serving Fabric for Science

Exploding data volumes and velocities, new computational methods and platforms, and ubiquitous connectivity demand new approaches to computation in the sciences. These new approaches must enable computation to be mobile, so that, for example, it can occur near data, be triggered by events (e.g., arrival of new data), be offloaded to specialized accelerators, or run remotely where resources are available. They also require new design approaches in which monolithic applications can be decomposed into smaller components, that may in turn be executed separately and on the most suitable resources. To address these needs we present funcX---a distributed function as a service (FaaS) platform that enables flexible, scalable, and high performance remote function execution. funcX's endpoint software can transform existing clouds, clusters, and supercomputers into function serving systems, while funcX's cloud-hosted service provides transparent, secure, and reliable function execution across a federated ecosystem of endpoints. We motivate the need for funcX with several scientific case studies, present our prototype design and implementation, show optimizations that deliver throughput in excess of 1 million functions per second, and demonstrate, via experiments on two supercomputers, that funcX can scale to more than more than 130000 concurrent workers.Comment: Accepted to ACM Symposium on High-Performance Parallel and Distributed Computing (HPDC 2020). arXiv admin note: substantial text overlap with arXiv:1908.0490

Virtual Machine Image Management for Elastic Resource Usage in Grid Computing

Grid Computing has evolved from an academic concept to a powerful paradigm in the area of high performance computing (HPC). Over the last few years, powerful Grid computing solutions were developed that allow the execution of computational tasks on distributed computing resources. Grid computing has recently attracted many commercial customers. To enable commercial customers to be able to execute sensitive data in the Grid, strong security mechanisms must be put in place to secure the customers' data. In contrast, the development of Cloud Computing, which entered the scene in 2006, was driven by industry: it was designed with respect to security from the beginning. Virtualization technology is used to separate the users e.g., by putting the different users of a system inside a virtual machine, which prevents them from accessing other users' data. The use of virtualization in the context of Grid computing has been examined early and was found to be a promising approach to counter the security threats that have appeared with commercial customers. One main part of the work presented in this thesis is the Image Creation Station (ICS), a component which allows users to administer their virtual execution environments (virtual machines) themselves and which is responsible for managing and distributing the virtual machines in the entire system. In contrast to Cloud computing, which was designed to allow even inexperienced users to execute their computational tasks in the Cloud easily, Grid computing is much more complex to use. The ICS makes it easier to use the Grid by overcoming traditional limitations like installing needed software on the compute nodes that users use to execute the computational tasks. This allows users to bring commercial software to the Grid for the first time, without the need for local administrators to install the software to computing nodes that are accessible by all users. Moreover, the administrative burden is shifted from the local Grid site's administrator to the users or experienced software providers that allow the provision of individually tailored virtual machines to each user. But the ICS is not only responsible for enabling users to manage their virtual machines themselves, it also ensures that the virtual machines are available on every site that is part of the distributed Grid system. A second aspect of the presented solution focuses on the elasticity of the system by automatically acquiring free external resources depending on the system's current workload. In contrast to existing systems, the presented approach allows the system's administrator to add or remove resource sets during runtime without needing to restart the entire system. Moreover, the presented solution allows users to not only use existing Grid resources but allows them to scale out to Cloud resources and use these resources on-demand. By ensuring that unused resources are shut down as soon as possible, the computational costs of a given task are minimized. In addition, the presented solution allows each user to specify which resources can be used to execute a particular job. This is useful when a job processes sensitive data e.g., that is not allowed to leave the company. To obtain a comparable function in today's systems, a user must submit her computational task to a particular resource set, losing the ability to automatically schedule if more than one set of resources can be used. In addition, the proposed solution prioritizes each set of resources by taking different metrics into account (e.g. the level of trust or computational costs) and tries to schedule the job to resources with the highest priority first. It is notable that the priority often mimics the physical distance from the resources to the user: a locally available Cluster usually has a higher priority due to the high level of trust and the computational costs, that are usually lower than the costs of using Cloud resources. Therefore, this scheduling strategy minimizes the costs of job execution by improving security at the same time since data is not necessarily transferred to remote resources and the probability of attacks by malicious external users is minimized. Bringing both components together results in a system that adapts automatically to the current workload by using external (e.g., Cloud) resources together with existing locally available resources or Grid sites and provides individually tailored virtual execution environments to the system's users