Locally rigid, vessel-based registration for laparoscopic liver surgery

Purpose: Laparoscopic liver resection has significant advantages over open surgery due to less patient trauma and faster recovery times, yet is difficult for most lesions due to the restricted field of view and lack of haptic feedback. Image guidance provides a potential solution but is challenging in a soft deforming organ such as the liver. In this paper, we therefore propose a laparoscopic ultrasound (LUS) image guidance system and study the feasibility of a locally rigid registration for laparoscopic liver surgery. Methods: We developed a real-time segmentation method to extract vessel centre points from calibrated, freehand, electromagnetically tracked, 2D LUS images. Using landmark-based initial registration and an optional iterative closest point (ICP) point-to-line registration, a vessel centre-line model extracted from preoperative computed tomography (CT) is registered to the ultrasound data during surgery. Results: Using the locally rigid ICP method, the RMS residual error when registering to a phantom was 0.7 mm, and the mean target registration error (TRE) for two in vivo porcine studies was 3.58 and 2.99 mm, respectively. Using the locally rigid landmark-based registration method gave a mean TRE of 4.23 mm using vessel centre lines derived from CT scans taken with pneumoperitoneum and 6.57 mm without pneumoperitoneum. Conclusion: In this paper we propose a practical image-guided surgery system based on locally rigid registration of a CT-derived model to vascular structures located with LUS. In a physical phantom and during porcine laparoscopic liver resection, we demonstrate accuracy of target location commensurate with surgical requirements. We conclude that locally rigid registration could be sufficient for practically useful image guidance in the near future

Medical Imaging of Microrobots: Toward In Vivo Applications

Medical microrobots (MRs) have been demonstrated for a variety of non-invasive biomedical applications, such as tissue engineering, drug delivery, and assisted fertilization, among others. However, most of these demonstrations have been carried out in in vitro settings and under optical microscopy, being significantly different from the clinical practice. Thus, medical imaging techniques are required for localizing and tracking such tiny therapeutic machines when used in medical-relevant applications. This review aims at analyzing the state of the art of microrobots imaging by critically discussing the potentialities and limitations of the techniques employed in this field. Moreover, the physics and the working principle behind each analyzed imaging strategy, the spatiotemporal resolution, and the penetration depth are thoroughly discussed. The paper deals with the suitability of each imaging technique for tracking single or swarms of MRs and discusses the scenarios where contrast or imaging agent's inclusion is required, either to absorb, emit, or reflect a determined physical signal detected by an external system. Finally, the review highlights the existing challenges and perspective solutions which could be promising for future in vivo applications

Latency and Distortion compensation in Augmented Environments using Electromagnetic trackers

Augmented reality (AR) systems are often used to superimpose virtual objects or information on a scene to improve situational awareness. Delays in the display system or inaccurate registration of objects destroy the sense of immersion a user experiences when using AR systems. AC electromagnetic trackers are ideally for these applications when combined with head orientation prediction to compensate for display system delays. Unfortunately, these trackers do not perform well in environments that contain conductive or ferrous materials due to magnetic field distortion without expensive calibration techniques. In our work we focus on both the prediction and distortion compensation aspects of this application, developing a “small footprint” predictive filter for display lag compensation and a simplified calibration system for AC magnetic trackers. In the first phase of our study we presented a novel method of tracking angular head velocity from quaternion orientation using an Extended Kalman Filter in both single model (DQEKF) and multiple model (MMDQ) implementations. In the second phase of our work we have developed a new method of mapping the magnetic field generated by the tracker without high precision measurement equipment. This method uses simple fixtures with multiple sensors in a rigid geometry to collect magnetic field data in the tracking volume. We have developed a new algorithm to process the collected data and generate a map of the magnetic field distortion that can be used to compensation distorted measurement data

Electronic and Photonic Systems WILGA 2014

Symposium Wilga 2014, in its 34th edition, was organized during the last week of May. Symposium is organized under the auspices of SPIE, IEEE, Photonics Society of Poland, WEiTI PW, and PKOpto SEP. The event gathered around 350 persons, mainly young researchers from the  whole country. There were presented around 250 speeches and communications. The main book of Symposium Proceedings is Proc. SPIE vol.9290 which contains around 130 papers. A few tens of papers were also published in technical journals. The leading topics of Wilga 2014 were gathered in key sessions: nano-materials for photonics and electronics, astronomy and space technology, biomedicine, computational intelligence, visualization and multimedia, and large research experiments. The paper presents a digest of some topical tracks, and chosen  work results presented during WILGA 2014 Symposium

Electromagnetic Tracking for Medical Imaging

This thesis explores the novel use of a wireless electromagnetic: EM) tracking device in a Computed Tomography: CT) environment. The sources of electromagnetic interference inside a Philips Brilliant Big Bore CT scanner are analyzed. A research version of the Calypso wireless tracking system was set up inside the CT suite, and a set of three Beacon transponders was bonded to a plastic fixture. The tracking system was tested under different working parameters including orientation of tracking beacons, the gain level of the frontend amplifier, the distance between the transponders and the sensor array, the rotation speed of the CT gantry, and the presence/absence of the CT X-ray source. The performance of the tracking system reveals two obvious factors which bring in electromagnetic interference: 1) metal like effect brought in by carbon fiber patient couch and 2) electromagnetic disturbance due to spinning metal inside the CT gantry. The accuracy requirements for electromagnetic tracking in the CT environment are a Root Mean Square: RMS) error of \u3c2 mm in stationary position tracking. Within a working volume of 120×120×120 mm3 centered 200 mm below the sensor array, the tracking system achieves the desired clinical goal

Calibration Methods for Head-Tracked 3D Displays

Head-tracked 3D displays can provide a compelling 3D effect, but even small inaccuracies in the calibration of the participant’s viewpoint to the display can disrupt the 3D illusion. We propose a novel interactive procedure for a participant to easily and accurately calibrate a head-tracked display by visually aligning patterns across a multi-screen display. Head-tracker measurements are then calibrated to these known viewpoints. We conducted a user study to evaluate the effectiveness of different visual patterns and different display shapes. We found that the easiest to align shape was the spherical display and the best calibration pattern was the combination of circles and lines. We performed a quantitative camera-based calibration of a cubic display and found visual calibration outperformed manual tuning and generated viewpoint calibrations accurate to within a degree. Our work removes the usual, burdensome step of manual calibration when using head-tracked displays and paves the way for wider adoption of this inexpensive and effective 3D display technology

1999 Flight Mechanics Symposium

This conference publication includes papers and abstracts presented at the Flight Mechanics Symposium held on May 18-20, 1999. Sponsored by the Guidance, Navigation and Control Center of Goddard Space Flight Center, this symposium featured technical papers on a wide range of issues related to orbit-attitude prediction, determination, and control; attitude sensor calibration; attitude determination error analysis; attitude dynamics; and orbit decay and maneuver strategy. Government, industry, and the academic community participated in the preparation and presentation of these papers