Service quality measurements for IPv6 inter-networks

Measurement-based performance evaluation of network traffic is becoming very important, especially for networks trying to provide differentiated levels of service quality to the different application flows. The non-identical response of flows to the different types of network-imposed performance degradation raises the need for ubiquitous measurement mechanisms, able to measure numerous performance properties, and being equally applicable to different applications and transports. This paper presents a new measurement mechanism, facilitated by the steady introduction of IPv6 in network nodes and hosts, which exploits native features of the protocol to provide support for performance measurements at the network (IP) layer. IPv6 Extension Headers have been used to carry the triggers involving the measurement activity and the measurement data in-line with the payload data itself, providing a high level of probability that the behaviour of the real user traffic flows is observed. End-to-end one-way delay, jitter, loss, and throughput have been measured for applications operating on top of both reliable and unreliable transports, over different-capacity IPv6 network configurations. We conclude that this technique could form the basis for future Internet measurements that can be dynamically deployed where and when required in a multi-service IP environment

Inference of single-cell phylogenies from lineage tracing data using Cassiopeia.

The pairing of CRISPR/Cas9-based gene editing with massively parallel single-cell readouts now enables large-scale lineage tracing. However, the rapid growth in complexity of data from these assays has outpaced our ability to accurately infer phylogenetic relationships. First, we introduce Cassiopeia-a suite of scalable maximum parsimony approaches for tree reconstruction. Second, we provide a simulation framework for evaluating algorithms and exploring lineage tracer design principles. Finally, we generate the most complex experimental lineage tracing dataset to date, 34,557 human cells continuously traced over 15 generations, and use it for benchmarking phylogenetic inference approaches. We show that Cassiopeia outperforms traditional methods by several metrics and under a wide variety of parameter regimes, and provide insight into the principles for the design of improved Cas9-enabled recorders. Together, these should broadly enable large-scale mammalian lineage tracing efforts. Cassiopeia and its benchmarking resources are publicly available at www.github.com/YosefLab/Cassiopeia

Economic Evidence on the Effects of the Indian Gaming Regulatory Act on Indians and Non-Indians

When Congress passed the Indian Gaming Regulatory Act (IGRA) in 1988, some tribal leaders perceived the state compacting provision required for casino-style gaming on tribal lands as an erosion of tribal sovereignty that could undermine their early economic development successes and disrupt a precariously successful federal-tribal relationship with regard to tribal self-determination. In hindsight, however, the substantial growth and myriad positive impacts of the first twenty years of tribal gaming under IGRA reveal the ways that the federal regulatory framework laid out in the law resolved numerous legal dilemmas that had plagued tribal gaming expansion. It is now clear that the predictability provided by successful tribal- state compact negotiations allowed the necessary capital investments to produce a robust tribal government gaming industry across much of Indian Country. Therefore, an analysis of tribal government gaming’s impacts on tribal communities and neighboring localities is best framed in the context of the federal law that continues to shape the industry today

Governing culture: legislators, interpreters and accountants

Cultural policy has become dominated by questions of how to account for the intangible value of government investments. This is as a result of longstanding developments within government’s approaches to policy making, most notably those influenced by practices of audit and accounting. This paper will outline these developments with reference to Peter Miller’s concept of calculative practices, and will argue two central points: first, that there are practical solutions to the problem of measuring the value of culture that connect central government discourses with the discourses of the cultural sector; and second, the paper will demonstrate how academic work has been central to this area of policy making. As a result of the centrality of accounting academics in cultural policy, for example in providing advice on the appropriate measurement tools and techniques, questions are raised about the role academia might take vis-à-vis public policy. Accounting professionals and academics not only provide technical expertise that informs state calculative practices, but also play a surveillance role through the audit and evaluation of government programmes, and act as interpreters in defining terms of performance measurement, success and failure. The paper therefore concludes by reflecting on recent work by Phillip Schlesinger to preserve academic integrity whilst allowing accounting scholars and academics influence and partnership in policy

Defining And Measuring Green FDI: An Exploratory Review Of Existing Work And Evidence

This paper was developed at the request of the OECD Working Party of the Investment Committee to document efforts to date to define and measure green FDI and to investigate the practicability of various possible definitions, as well as to identify investment policy restrictions to green FDI. It does so by reviewing the literature and existing work on the contributions of FDI to the environment; by providing a two-part definition of green FDI; and by discussing various assumptions necessary to estimate the magnitude of \u27green\u27 FDI

Spatial networks with wireless applications

Many networks have nodes located in physical space, with links more common between closely spaced pairs of nodes. For example, the nodes could be wireless devices and links communication channels in a wireless mesh network. We describe recent work involving such networks, considering effects due to the geometry (convex,non-convex, and fractal), node distribution, distance-dependent link probability, mobility, directivity and interference.Comment: Review article- an amended version with a new title from the origina