Data-driven methods for analyzing ballistocardiograms in longitudinal cardiovascular monitoring

Cardiovascular disease (CVD) is the leading cause of death in the US; about 48% of American adults have one or more types of CVD. The importance of continuous monitoring of the older population, for early detection of changes in health conditions, has been shown in the literature, as the key to a successful clinical intervention. We have been investigating environmentally-embedded in-home networks of non-invasive sensing modalities. This dissertation concentrates on the signal processing techniques required for the robust extraction of morphological features from the ballistocardiographs (BCG), and machine learning approaches to utilize these features in non-invasive monitoring of cardiovascular conditions. At first, enhancements in the time domain detection of the cardiac cycle are addressed due to its importance in the estimation of heart rate variability (HRV) and sleep stages. The proposed enhancements in the energy-based algorithm for BCG beat detection have shown at least 50% improvement in the root mean square error (RMSE) of the beat to beat heart rate estimations compared to the reference estimations from the electrocardiogram (ECG) R to R intervals. These results are still subject to some errors, primarily due to the contamination of noise and motion artifacts caused by floor vibration, unconstrained subject movements, or even the respiratory activities. Aging, diseases, breathing, and sleep disorders can also affect the quality of estimation as they slightly modify the morphology of the BCG waveform.Includes bibliographical reference

Performance Comparison for Ballistocardiogram Peak Detection Methods

Citation: Suliman, A., Carlson, C., Ade, C. J., Warren, S., & Thompson, D. E. (2019). Performance Comparison for Ballistocardiogram Peak Detection Methods. IEEE Access, 7, 53945–53955. https://doi.org/10.1109/ACCESS.2019.2912650A number of research groups have proposed methods for ballistocardiogram (BCG) peak detection toward the identification of individual cardiac cycles. However, objective comparisons of these proposed methods are lacking. This paper, therefore, conducts a systematic and objective performance evaluation and comparison of several of these approaches. Five peak-detection methods (three replicated from the literature and two adapted from code provided by the methods' authors) are compared using data from 30 volunteers. A basic cross-correlation approach was also included as a sixth method. Two high-performing methods were identified: the method proposed by Sadek et al. and the method proposed by Brüser et al. The first achieved the highest average peak-detection rate of 94%, the lowest average false alarm rate of 0.0552 false alarms per second, and a relatively small mean absolute error between the real and detected peaks: 0.0175 seconds. The second method achieved the lowest mean absolute error of 0.0088 seconds between the real and detected peaks, an average peak-detection success rate of 89%, and 0.0766 false alarms per second. All metrics are averaged across participants

Adaptive Heartbeat Modeling for Beat-to-Beat Heart Rate Measurement in Ballistocardiograms

Peer reviewe

A smart cushion for real-time heart rate monitoring

10.1109/BioCAS.2012.64185122012 IEEE Biomedical Circuits and Systems Conference: Intelligent Biomedical Electronics and Systems for Better Life and Better Environment, BioCAS 2012 - Conference Publications53-5

Comparison of HRV Indices of ECG and BCG Signals

Electrocardiography (ECG) plays a significant role in diagnosing heart-related issues, it provides, accurate, fast, and dependable insights into crucial parameters like QRS complex duration, the R-R interval, and the occurrence, amplitude, and duration of P, R, and T waves. However, utilizing ECG for prolonged monitoring poses challenges as it necessitates connecting multiple electrodes to the patient's body. This can be discomforting and disruptive, hampering the attainment of uninterrupted recordings. Ballistocardiography (BCG) emerges as a promising substitute for ECG, presenting a non-invasive technique for recording the heart's mechanical activity. BCG signals can be captured using sensors positioned beneath the bed, thereby providing enhanced comfort and convenience for long-term monitoring of the subject. In a recent study, researchers compared the heart rate variability (HRV) indices derived from simultaneously acquired ECG and BCG signals. Encouragingly, the BCG signal yielded satisfactory results similar to those obtained from ECG, implying that BCG holds potential as a viable alternative for prolonged monitoring. The findings of this study carry substantial implications for the advancement of innovative, non-invasive methods in monitoring heart health. BCG showcases the ability to offer a more comfortable and convenient alternative to ECG while retaining its capacity to deliver accurate and reliable cardiac information concerning a patient's condition.Comment: 8 Pages, 6 Figures, International Journal of Modern Trends in Engineering and Researc

A Hidden Markov Model for Seismocardiography

This is the author accepted manuscript. The final version is available from Institute of Electrical and Electronics Engineers (IEEE) via the DOI in this record.We propose a hidden Markov model approach for processing seismocardiograms. The seismocardiogram morphology is learned using the expectation-maximization algorithm, and the state of the heart at a given time instant is estimated by the Viterbi algorithm. From the obtained Viterbi sequence, it is then straightforward to estimate instantaneous heart rate, heart rate variability measures, and cardiac time intervals (the latter requiring a small number of manual annotations). As is shown in the conducted experimental study, the presented algorithm outperforms the state-of-the-art in seismocardiogram-based heart rate and heart rate variability estimation. Moreover, the isovolumic contraction time and the left ventricular ejection time are estimated with mean absolute errors of about 5 [ms] and 9 [ms], respectively. The proposed algorithm can be applied to any set of inertial sensors; does not require access to any additional sensor modalities; does not make any assumptions on the seismocardiogram morphology; and explicitly models sensor noise and beat-to-beat variations (both in amplitude and temporal scaling) in the seismocardiogram morphology. As such, it is well suited for low-cost implementations using off-the-shelf inertial sensors and targeting, e.g., at-home medical services

Extracting Cardiac Information From Medical Radar Using Locally Projective Adaptive Signal Separation

Electrocardiography is the gold standard for electrical heartbeat activity, but offers no direct measurement of mechanical activity. Mechanical cardiac activity can be assessed non-invasively using, e.g., ballistocardiography and recently, medical radar has emerged as a contactless alternative modality. However, all modalities for measuring the mechanical cardiac activity are affected by respiratory movements, requiring a signal separation step before higher-level analysis can be performed. This paper adapts a non-linear filter for separating the respiratory and cardiac signal components of radar recordings. In addition, we present an adaptive algorithm for estimating the parameters for the non-linear filter. The novelty of our method lies in the combination of the non-linear signal separation method with a novel, adaptive parameter estimation method specifically designed for the non-linear signal separation method, eliminating the need for manual intervention and resulting in a fully adaptive algorithm. Using the two benchmark applications of (i) cardiac template extraction from radar and (ii) peak timing analysis, we demonstrate that the non-linear filter combined with adaptive parameter estimation delivers superior results compared to linear filtering. The results show that using locally projective adaptive signal separation (LoPASS), we are able to reduce the mean standard deviation of the cardiac template by at least a factor of 2 across all subjects. In addition, using LoPASS, 9 out of 10 subjects show significant (at a confidence level of 2.5%) correlation between the R-T-interval and the R-radar-interval, while using linear filters this ratio drops to 6 out of 10. Our analysis suggests that the improvement is due to better preservation of the cardiac signal morphology by the non-linear signal separation method. Hence, we expect that the non-linear signal separation method introduced in this paper will mostly benefit analysis methods investigating the cardiac radar signal morphology on a beat-to-beat basis