895 research outputs found

    Anelastic deformation of boron fibers

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    The flexural deformation behavior of vapor-deposited boron fibers was examined from 100 to 1100 K by stress-relaxation and internal friction techniques. Only strong thermally-activated anelasticity was observed with no evidence of plasticity up to surface strains of 0.006. The parameters governing the relaxation processes within the anelastic spectra of as-received and annealed fibers were determined. These parameters were correlated with X-ray structure studies to develop preliminary models for the sources of boron's anelasticity. The large relaxation strengths of the dominant Ia processes coupled with their relaxation times and energies suggest a sliding mechanism between certain basic structural subunits common to both the beta-rhombohedral and vapor-deposited boron structures

    General Modified Friedmann Equations in Rainbow Flat Universe, by Thermodynamics

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    We investigate the derivation of Friedmann equations in Rainbow gravity following Jacobson thermodynamic approach. We do not restrict the rainbow functions to be constant as is customarily used, and show that the first law of thermodynamics with a corresponding `classical' proportionality between entropy and surface area, supplemented eventually by a `quantum' logarithmic correction, are not in general sufficient to obtain the equations in flat FRW metrics.Comment: 7 pages, to appear in EPJ

    Molecular Genetic Characterization of the Biosynthesis Cluster of a Prenylated Isoindolinone Alkaloid Aspernidine A in Aspergillus nidulans

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    Aspernidine A is a prenylated isoindolinone alkaloid isolated from the model fungus Aspergillus nidulans. A genome-wide kinase knock out library of A. nidulans was examined and it was found that a mitogen-activated protein kinase gene, mpkA, deletion strain produces aspernidine A. Targeted gene deletions were performed in the kinase deletion background to identify the gene cluster for aspernidine A biosynthesis. Intermediates were isolated from mutant strains which provided information about the aspernidine A biosynthesis pathway

    Patterns of management of patients with dual disorder (psychosis) in Italy: a survey of psychiatrists and other physicians focusing on clinical practice

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    © 2018 Clerici, de Bartolomeis, De Filippis, Ducci, Maremmani, Martinotti and Schifano. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).Patients with severe psychotic disorders such as schizophrenia, schizoaffective and bipolar disorders frequently suffer from concomitant substance use disorders (SUDs) – Dual Disorder (DD) patients. In order to better understand current practices for management of patients with psychotic episodes and concomitant SUD in Italy, we carried out a survey of psychiatrists on current routine practice among prescribers. These aspects can help to identify at-risk patients, improve current prescribing practices, and favor early intervention. An ad hoc survey of 17 questions was administered to psychiatrists via electronic polling and on-line distribution; 448 completed questionnaires were collected. Comorbid substance abuse was most frequently diagnosed within the context of anxiety disorder (46%), followed by bipolar disorder (25%), and schizophrenia/schizoaffective disorder (12%). The vast majority of respondents felt that patient management was becoming more complex due to substance abuse. The areas reported to be most affected in patients with SUD were functioning, interpersonal relations, and impulsivity, while sensory perception disorders, ideation, agitation, and impulsivity were the most frequently reported symptoms. In the acute setting, haloperidol was used as the first-line agent of choice followed by aripiprazole and olanzapine. In the maintenance phase, aripiprazole was the dominantly used first-line agent, followed by olanzapine. Almost half of respondents used long-acting agents, while about one-third did not. Among those prescribing long-acting agents, efficacy, control of impulsivity, and control of specific symptoms were cited as motivators, while in the maintenance phase, better adherence and tolerability were mainly cited. From the responses to the present survey, it is clear that the respondents are aware of the problem of SUD in psychotic patients. While treatment be optimized in terms of the choice and formulation of antipsychotics, greater emphasis should be placed on efficacy, tolerability and the negative metabolic consequences of some antipsychotics. When considering the ideal antipsychotic, long-acting agents were considered to be superior in reducing relapse, even if current treatment guidelines often give preference to oral formulations.Peer reviewe

    How to Keep Schools Open

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    Date unknownhttps://egrove.olemiss.edu/citizens_pamph/1038/thumbnail.jp

    Enty, Exit and Productivitry - Empirical Results for German Manufacturing Industries

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    Using panel data from Spain Farinas and Ruano (IJIO 2005) test three hypotheses from a model by Hopenhayn (Econometrica 1992): (H1) Firms that exit in year t were in t-1 less productive than firms that continue to produce in t. (H2) Firms that enter in year t are less productive than incumbent firms in year t. (H3) Surviving firms from an entry cohort were more productive than non-surviving firms from this cohort in the start year. Results for Spain support all three hypotheses. This paper replicates the study using a unique newly available panel data sets for all manufacturing plants from Germany (1995 – 2002). Again, all three hypotheses are supported empirically.Exports, Entry, exit, productivity
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