Nanoinformatics: developing new computing applications for nanomedicine

Nanoinformatics has recently emerged to address the need of computing applications at the nano level. In this regard, the authors have participated in various initiatives to identify its concepts, foundations and challenges. While nanomaterials open up the possibility for developing new devices in many industrial and scientific areas, they also offer breakthrough perspectives for the prevention, diagnosis and treatment of diseases. In this paper, we analyze the different aspects of nanoinformatics and suggest five research topics to help catalyze new research and development in the area, particularly focused on nanomedicine. We also encompass the use of informatics to further the biological and clinical applications of basic research in nanoscience and nanotechnology, and the related concept of an extended ?nanotype? to coalesce information related to nanoparticles. We suggest how nanoinformatics could accelerate developments in nanomedicine, similarly to what happened with the Human Genome and other -omics projects, on issues like exchanging modeling and simulation methods and tools, linking toxicity information to clinical and personal databases or developing new approaches for scientific ontologies, among many others

Fog computing, applications , security and challenges, review

The internet of things originates a world where on daily basis objects can join the internet and interchange information and in addition process, store, gather them from the nearby environment, and effectively mediate on it. A remarkable number of services might be imagined by abusing the internet of things. Fog computing which is otherwise called edge computing was introduced in 2012 as a considered is a prioritized choice for the internet of things applications. As fog computing extend services of cloud near to the edge of the network and make possible computations, communications, and storage services in proximity to the end user. Fog computing cannot only provide low latency, location awareness but also enhance real-time applications, quality of services, mobility, security and privacy in the internet of things applications scenarios. In this paper, we will summarize and overview fog computing model architecture, characteristic, similar paradigm and various applications in real-time scenarios such as smart grid, traffic control system and augmented reality. Finally, security challenges are presented

Advances in GPU architecture for deep learning and scientific computing

The talk will cover the recent NVIDIA product announcements made at the GTC'16 conference, and how the Pascal GPU and NVLink interconnect technologies greatly improve multi-GPU performance and efficiency in deep learning and scientific computing applications

Towards a Tool-based Development Methodology for Pervasive Computing Applications

Despite much progress, developing a pervasive computing application remains a challenge because of a lack of conceptual frameworks and supporting tools. This challenge involves coping with heterogeneous devices, overcoming the intricacies of distributed systems technologies, working out an architecture for the application, encoding it in a program, writing specific code to test the application, and finally deploying it. This paper presents a design language and a tool suite covering the development life-cycle of a pervasive computing application. The design language allows to define a taxonomy of area-specific building-blocks, abstracting over their heterogeneity. This language also includes a layer to define the architecture of an application, following an architectural pattern commonly used in the pervasive computing domain. Our underlying methodology assigns roles to the stakeholders, providing separation of concerns. Our tool suite includes a compiler that takes design artifacts written in our language as input and generates a programming framework that supports the subsequent development stages, namely implementation, testing, and deployment. Our methodology has been applied on a wide spectrum of areas. Based on these experiments, we assess our approach through three criteria: expressiveness, usability, and productivity

A multi-pronged empirical approach to mobile privacy investigation

We describe the design of three empirical studies planned as part of an investigation into privacy when mobile. The studies exemplify complementary investigation strands, whose aim is to uncover the multi-faceted nature of privacy for mobile computing applications

Belousov-Zhabotinsky droplet mixing on-chip for chemical computing applications

Without an imposed physical structure, even the most complex chemistries are limited in their ability to process information. For example, the Belousov-Zhabotinsky (BZ) oscillating reaction has been shown to have information procession potential, but only if structure is imposed e.g. using physical barriers or light-sensitive catalysts. Recently, separated BZ droplets in oil have been investigated. Another option for aqueous/oil systems is to add lipid into the oil, which self-assembles into a monolayer at the phase boundary. If the lipid-stabilised droplets are brought into contact, a bilayer is formed, separating the BZ droplets into compartments. This technique is more flexible than other methods of imparting structure, allowing for the creation of droplet arrays inspired by biological neuronal networks

String Matching with Multicore CPUs: Performing Better with the Aho-Corasick Algorithm

Multiple string matching is known as locating all the occurrences of a given number of patterns in an arbitrary string. It is used in bio-computing applications where the algorithms are commonly used for retrieval of information such as sequence analysis and gene/protein identification. Extremely large amount of data in the form of strings has to be processed in such bio-computing applications. Therefore, improving the performance of multiple string matching algorithms is always desirable. Multicore architectures are capable of providing better performance by parallelizing the multiple string matching algorithms. The Aho-Corasick algorithm is the one that is commonly used in exact multiple string matching algorithms. The focus of this paper is the acceleration of Aho-Corasick algorithm through a multicore CPU based software implementation. Through our implementation and evaluation of results, we prove that our method performs better compared to the state of the art

Towards ad-hoc situation determination

Toolkits such as PlaceLab [1] have been successful in making location information freely available for use in experimental ubiquitous computing applications. As users' expectations of ubiquitous computing applications grow, we envisage a need for tools that can deliver a much richer set of contextual information. The high-level situation of the current environment is a key contextual element, and this position paper focuses on a method to provide this information for an ad-hoc group of people and devices. The contributions of this paper are i) a demonstration of how information retrieval (IR) techniques can be applied to situation determination in context-aware systems, ii) a proposal of a novel approach to situation determination that combines these adapted IR techniques with a process of cooperative interaction, and iii) a report of preliminary results. The approach offers a high level of utility and accuracy, with a greater level of automation than other contemporary approaches

Soft computing applications in dynamic model identification of polymer extrusion process

This paper proposes the application of soft computing to deal with the constraints in conventional modelling techniques of the dynamic extrusion process. The proposed technique increases the efficiency in utilising the available information during the model identification. The resultant model can be classified as a ‘grey-box model’ or has been termed as a ‘semi-physical model’ in the context. The extrusion process contains a number of parameters that are sensitive to the operating environment. Fuzzy ruled-based system is introduced into the analytical model of the extrusion by means of sub-models to approximate those operational-sensitive parameters. In drawing the optimal structure for the sub-models, a hybrid algorithm of genetic algorithm with fuzzy system (GA-Fuzzy) has been implemented. The sub-models obtained show advantages such as linguistic interpretability, simpler rule-base and less membership functions. The developed model is adaptive with its learning ability through the steepest decent error back-propagation algorithm. This ability might help to minimise the deviation of the model prediction when the operational-sensitive parameters adapt to the changing operating environment in the real situation. The model is first evaluated through simulations on the consistency of model prediction to the theoretical analysis. Then, the effectiveness of adaptive sub-models in approximating the operational-sensitive parameters during the operation is further investigated