Prospective teachers of physical education and sport schools and faculty of education student teachers scientific epistemological beliefs in terms of different variables comparison of ( example of Firat University)

Epistemoloji, bilgiyi araştıran bir felsefi akımdır. Epistemolojik inanç ise bireyin, bilgiyi nasıl öğrendiği ve öğrettiğine yönelik kendi kişisel yorumlarıdır. Öyle ki epistemolojik inanç, bireylerin yaşamları süresince aldığı bütün kararları ve bu kararları uygularken sergilemiş oldukları davranışların sebeplerini oluşturmaktadır. Epistemolojik inancın kendine has özellikleri bulunurken oluşumunu ve gelişimini çeşitli değişkenler etkilemektedir. Bu değişkenler aile yapısı, içinde yaşanılan çevre, yaş faktörü ve eğitim düzeyi olarak sıralandırabiliriz. Bu araştırma, 2012-2013 eğitim öğretim yılında Fırat Üniversitesi Eğitim Fakültesi 4. sınıf öğretmen adayları ile Beden Eğitimi ve Spor Yüksekokulu 3. ve 4. sınıf öğretmen adaylarının bilimsel epistemolojik inançlarının düzeyini çeşitli değişkenler açısından incelemek amacıyla yapılan, tarama modelli bir çalışmadır.Araştırmanın çalışma grubunu Fırat Üniversitesi Beben Eğitimi ve Spor Yüksekokulu 3. ve 4. sınıf öğretmen adayları ile Eğitim Fakültesi 4.sınıf öğretmen adayları oluşturmaktadır. Araştırmada Pomeroy (1993) tarafından geliştirilen ve Deryakulu ve Bıkmaz (2003) tarafından Türkçeye uyarlanan “Bilimsel Epistemolojik İnançlar Ölçeği” kullanılmıştır. Araştırmada elde edilen verilerin analizinde SPSS 15 istatistik programı kullanılmış, değişkenler arasındaki farkta 0.05 önem düzeyi dikkate alınmıştır. Sonuç olarak; öğretmen adaylarının bölüm, cinsiyet, yaş, bölümü kendi istekleri ile seçmiş olmaları ve araştırma yapmayı sevmeleri gibi değişkenler ile “bilimsel epistemolojik inançlar” arasında anlamlı ilişki tespit edilmekle beraber, bilimsel epistemolojik inanç düzeyinin, Beden Eğitimi ve Spor Yüksekokulu öğretmen adaylarının Eğitim Fakültesi öğretmen adaylarından daha yüksek olduğu görülmüştür.Epistemology is philosophical movement that searches for the knowledge. Epistemological belief is the person’s own comments about how one learns and teaches the knowledge. So, the epistemological beliefs demonstrate all decisions taken during the lives of individuals and the causes of their behaviors exhibited when implementing these decisions. While the epistemological belief has its own characteristics, several variables affect the formation and development of it. These variables can be listed as family structure, the environment in which individuals live, age factor and level of education. This survey examines 2012-2013 acadamic year Fırat University both Faculty of Education 4th grade prospective teacher and school of physical education and sport 3rd and 4th grade prospective teacher’s scientific epistemological belief level in terms of variable variances. This survey’s work group is consisted of Fırat University Faculty of Education 4th grade prospective teachers and school of physical education and sport 3rd and 4th grade prospective teachers. In this study, “Bilimsel Epistemolojik İnançlar Ölçeği” is used. It is developed by Pomeroy (1993) and adaptated to Turkish by Deryakulu and Bıkmaz. For the analysis of the datas in that study, the SPSS 15 statistic program is used. Also, 0.05 importance level is considered for the differences among the variances. As a result, prospective teachers have selected that department voluntarily and they like searching. There are meaningful relationships between these variances and scientific epistemological beliefs. Moreover, it is observed that school of physical education prospective teachers’ level of scientific epistemological belief is higher than Faculty of Education prospective teachers

Psychosocial predictors of the fear of childbirth in Turkish pregnant women

Introduction Fear of childbirth (FOC) affects women’s emotional health, preparation for birth, and outcomes of birth. Identifying the predictors of FOC can aid in identifying strategies for reducing women’s FOC. Objective This descriptive, cross-sectional study was aimed at determining the psychosocial predictors of FOC in pregnant women. Methods The participants were 624 nulliparous and multiparous pregnant women in their last trimester. Data were collected using a personal information form, Wijma Delivery Expectancy/Experience Questionnaire A, Childbirth Self-Efficacy Inventory, Multidimensional Scale of Perceived Social Support, State-Trait Anxiety Inventory, and Prenatal Self-Evaluation Questionnaire. Hierarchical regression analysis was performed to determine the predictors of FOC. Results FOC was high among this study’s participants and severe for one fifth of them. The psychosocial variables predicting FOC were self-efficacy and trait anxiety level, and spousal support was found to be a mediator variable in the relationship between self-efficacy and FOC. Conclusion The findings suggest that psychosocial variables are key to predicting FOC

WILMS TUMOR: SINGLE CENTER EXPERİENCE

Background and AimsTo evaluate the clinical and pathological characteristics and treatmentoutcome of Wilms tumour (WT) cases treated in our institution.MethodsBetween 1988-2021, patients with WT were reviewed retrospectively.Twentysix patients were treated accoding to the TPOG-WT protocol, remainingpatients were treated according to the NWTS protocol.ResultsSixtyone patients were eligible out of 71. The median age was 44 months,M/F:0.7. Median duration of complaints was one month. There were threefamilial-WT. Genetic abnormalities were genitourinary abnormalities (n:5),hemihyperplasia (n:3), aniridia (n:1), Denys-Drash (n:1), BeckwithWiedaman(n:1), DICER 1 syndrome (n:1). Tumour was unilateral in 97% of cases.There was one patient with extrarenal-WT. Complete tumour resection wasperformed in all except two cases. There were intraoperative tumour rupture(n:6) and partial resection (n:2) in patients without neoadjuvan chemotheraphy(n:26). Stage distribution was stage-1 27%, stage-2 17%, stage-3 20%, stage-423%, stage-5 3%. There were 20 metastatic patients (pulmonary:18, liver:6,bone:2). Histopathology revealed 76% FH, 24% UH. Intraoperative complicationswere not observed in patients who were given preoperative CT, and completetumor excision could be performed in all of them. Radiotheraphy was performedto the primary tumour site in 22 cases, to whole abdomen in ten cases. Medianfollow-up-time was 43 months for all cases, and 5-years OS was 83%, 10,15-years OS were 79%. Nine patients relapsed, three of them primary, otherssystemic relapse. Median relapse time:10 months. Additional three patients hadrefractory disease. Ten patients died with disease progression. 5-years EFS was68%,10, 15-years EFS were 61%.ConclusionsObtained survival rates were similar with original protocols. No prognosticfactor could be determined owing to the limited patient number but stage andpresence of anaplasia are important criteria.</p

Inflammatory comorbidities ın the largest pediatric Familial Mediterranean fever cohort: a multicenter retrospective study of Pediatric Rheumatology Academy (PeRA)-Research Group (RG)

Aim: The aim of this study was to investigate the frequency and type of FMF-associated inflammatory diseases in a large FMF pediatric patients and to compare them to those FMF patients without concomitant inflammatory diseases. Materials and methods: Familial Mediterranean fever patients enrolled in the Pediatric Rheumatology Academy (PeRA)-Research Group (RG) were included. The patients were divided into two groups according to concomitant inflammatory disease as FMF patients who had a concomitant inflammatory disease (group 1) and FMF patients who did not have a concomitant inflammatory disease (group 1). The clinical findings and treatments were compared between the two groups. Results: The study group comprised 3475 patients with FMF. There were 294 patients (8.5%) in group 1 and 3181 patients (91.5%) in group 2. Juvenile idiopathic arthritis (n = 136) was the most common accompanying inflammatory disease. Arthritis, M694V homozygosity, and the need for biological therapy were more frequently observed in Group 1 (p < 0.05). Fever and abdominal pain were more frequently detected in Group 2 (p < 0.05). FMF patients with concomitant inflammatory diseas more frequently demonstrated colchicine resistance. There were no significant differences in the median attack frequency, chest pain, amyloidosis, erysipelas-like erythema, or family history of FMF between the two patient groups. Conclusion: To the best of our knowledge, this is the largest pediatric cohort reviewed to date. FMF patients may have different clinical profiles and colchicine responses if they have with concomitant inflammatory diseases. Key points • FMF is associated with some inflammatory comorbidities diseases. • To the best of our knowledge, this is the largest cohort evlauated pediatric FMF associated inflammatory comorbidities diseases reviewed to dat

The safety of canakinumab in systemic juvenile idiopathic arthritis and autoinflammatory diseases in pediatric patients: a multicenter study

Objective: To evaluate the safety of canakinumab using real-world data in patients with systemic juvenile idiopathic arthritis (sJIA) and autoinflammatory diseases (AID). Research design and methods: This was a cross-sectional observational, multicenter study. Patients diagnosed with AID and sJIA treated with canakinumab were included in the study. The participating 13 centers retrospectively collected their patients’ data. Results: A total of 335 patients were involved in the study. Among these patients, 280 were in the AID group and 55 were in the sJIA group. Canakinumab was administered at a median dose of 3 (2.5–4) mg/kg. The median total exposure time to canakinumab was 1.9 (0.8–3.2) years, corresponding to 759.5 patient-years. Seven hundred and seventy-nine total adverse events (AE) were identified. The total incidence of AE, and serious adverse events (SAE) throughout the study period was 1.02 per patient-years. The upper respiratory tract infection rate was 0.7 per patient-years, while the other infection rate was 0.13 per patient-years. While no death was observed in any patient, SAE were observed in 8 patients. Interstitial lung disease, anaphylaxis, or anaphylactoid reactions were not observed in any patient. Conclusions: Real-life data from a large cohort of patients suggests that canakinumab is as safe as claimed in clinical trials

Different types of exercise in Multiple Sclerosis: Aerobic exercise or Pilates, a single-blind clinical study

BACKROUND: The aim of our study is to examine effects of aerobic and Pilates exercises on disability, cognition, physical performance, balance, depression and fatigue in relapsing-remitting Multiple Sclerosis (MS) patients as compared to healthy controls

A score for predicting colchicine resistance at the time of diagnosis in familial Mediterranean fever: data from the TURPAID registry.

Objectives Colchicine forms the mainstay of treatment in FMF. Approximately 5-10% of FMF patients are colchicine resistant and require anti-IL-1 drugs. We aimed to compare the characteristics of colchicine-resistant and colchicine-responsive patients and to develop a score for predicting colchicine resistance at the time of FMF diagnosis. Methods FMF patients (0-18 years) enrolled in the Turkish Paediatric Autoinflammatory Diseases (TURPAID) registry were included. The predictive score for colchicine resistance was developed by using univariate/multivariate regression and receiver operating characteristics analyses. Results A total of 3445 FMF patients [256 (7.4%) colchicine-resistant and 3189 colchicine-responsive) were included (female:male ratio 1.02; median age at diagnosis 67.4 months). Colchicine-resistant patients had longer, more frequent attacks and were younger at symptom onset and diagnosis (P < 0.05). Fever, erysipelas-like erythema, arthralgia, arthritis, myalgia, abdominal pain, diarrhoea, chest pain, comorbidities, parental consanguinity and homozygosity/compound heterozygosity for exon 10 MEFV mutations were significantly more prevalent among colchicine-resistant than colchicine-responsive patients (P < 0.05). Multivariate logistic regression analysis in the training cohort (n = 2684) showed that age at symptom onset, attack frequency, arthritis, chest pain and having two exon 10 mutations were the strongest predictors of colchicine resistance. The score including these items had a sensitivity of 81.3% and a specificity of 49.1%. In the validation cohort (n = 671), its sensitivity was 93.5% and specificity was 53.8%. Conclusion We developed a clinician-friendly and practical predictive score that could help us identify FMF patients with a greater risk of colchicine resistance and tailor disease management individually at the time of diagnosis