123 research outputs found
Gas Sensing Properties of Rutile-tio2 (100) Films Prepared by Pulsed Laser Deposition
Gas sensing property of TiO2 thin films have been demonstrated in rutile-TiO2 (100) films grown on the a-Al2O3 (0001)substrates by Pulsed Laser Deposition (PLD). High quality rutile-TiO2 (100) films were successfully grown on a-Al2O3(0001) with the substrate temperature at 500oC under 15 mTorr of O2 gas pressure. The thickness and crystallinity ofTiO2 films were evaluated by Rutherford backscattering spectrometry combined with channeling (RBS/C) and X-raydiffraction using q-2q scans. To evaluate CO2 gas sensing property of TiO2 films, the dependence of the changing ofelectrical resistivity on the temperature was measured. It's found that high crystallinity rutile-TiO2 (100) films on the a-Al2O3 (0001) substrate kept at 100oC exhibits good gas sensing property for CO2 gas
Characterization of the effect of ion irradiation on industrially produced GdBa₂Cu₃O₇−δ superconducting tapes using a slow positron beam
To investigate the effect of irradiation-induced defects on the superconducting characteristics of industrially produced superconductor—GdBa₂Cu₃O₇−δ (GdBCO)—coated conductors (CCs), we irradiated the GdBCO CCs with Au ions at 2 or 10 MeV and probed them using a slow positron beam. Vacancy clusters were detected in both unirradiated and irradiated GdBCO CCs. However, the effect of ion irradiation on the GdBCO CCs was characterized as a slight reduction in the positron annihilation rate with low-momentum electrons. We also found a correlation between the annihilation rate of low-momentum electrons and the superconducting transition temperature
Visualization of pilot flame of an optically-accessible coaxially-staged aero-engine lean-burn fuel injector
[EN] The visualization of the pilot flame of a coaxially-staged aero-engine lean-burn fuel injector, not only downstream
but also inside of the pilot nozzle, was successfully performed at realistic aero-engine conditions. Optical access
toward the inside of the nozzle was achieved through the inner and outer shrouds, both of which were made of
transparent quartz. The image distortion caused by complex contours of the two shrouds was corrected by a
method based on optical ray tracing, which realized precise determination of spatial intensity distribution of optical
signals. Line-of-sight OH chemiluminescence, cross-sectional OH-LIF, kerosene LIF and kerosene Mie scattering
were employed as diagnostic tools. The effects of pilot local air-to-fuel ratio on spray flame structure were
revealed, both inside and downstream of the pilot nozzle under stable combustions. As the pilot mixture got rich,
the main reaction zone moved from inside of the pilot nozzle to the region near the injector lip downstream of the
injector exit. The OH-LIF signal was detected near the central axis surrounded by the fuel spray. It was also
observed near the back-step of the pilot nozzle for the rich cases. The experiments under combustion oscillation
were also conducted and the correlation of phenomena inside and downstream of the pilot nozzle was captured. It
was clarified that the reaction enhancement in the outer part of the lip vortex region was caused by the convection
of rich mixture, which appeared near the pilot atomizer lip at 150~210deg earlier oscillation phase angle.Matsuura, K.; Uesaka, S.; Iwasaki, T.; Kurosawa, Y.; Yamada, H.; Yamamoto, T.; Hayashi, S. (2017). Visualization of pilot flame of an optically-accessible coaxially-staged aero-engine lean-burn fuel injector. En Ilass Europe. 28th european conference on Liquid Atomization and Spray Systems. Editorial Universitat Politècnica de València. 855-872. https://doi.org/10.4995/ILASS2017.2017.475285587
Estimating a preference-based index from the Japanese SF-36
Objective: The main objective of the study was to estimate a preference-bascd Short Form (SF)-6D index from the SF-36 for Japan and compare it with the UK results.
Study Design and Setting: The SF-6D was translated into Japanese. Two hundred and forty-nine health states defined by this version of the SF-6D were then valued by a representative sample of 600 members of the Japanese general population using standard gamble (SG). These health-state values were modeled using classical parametric random-effect methods with individual-level data and ordinary least squares (OLS) on mean health-state values, together with a new nonparametric approach using Bayesian methods of estimation.
Results: All parametric models estimated on Japanese data were found to perform less well than their UK counterparts in terms of poorer goodness of fit, more inconsistencies, larger prediction errors and bias, and evidence of systematic bias in the predictions. Nonparametric models produce a substantial improvement in out-of-sample predictions. The physical, role, and social dimensions have relatively larger decrements than pain and mental health compared with those in the United Kingdom.
Conclusion: The differences between Japanese and UK valuations of the SF-6D make it important to use the Japanese valuation data set estimated using the nonparametric Bayesian technique presented in this article. (C) 2009 Elsevier Inc. All rights reserved
Three-dimensional imaging of a long-period stacking ordered phase in Mg₉₇Zn₁Gd₂ using high-voltage electron microscopy
Spatial configurations and lateral morphology of the 14H long-period stacking ordered (LPSO) phase have been studied by single tilt-axis electron tomography using high-voltage scanning transmission electron microscopy (STEM) operated at 1 MV. A "Quonset hut-like" lateral shape of the LPSO was found in a tomogram of a specimen as thick as 1.7 μ m. The reconstructed volume reveals spatial distribution of residual particulate precipitates of (Mg, Zn)3Gd phase 20-30 nm in diameters. The precipitates act as a source of solute elements for the formation and growth processes of 14H LPSO. 1 MV-STEM realizes enough resolution for imaging the morphology of LPSO as well as high electron transmittance (∼4.1 μ m) without any obvious electron irradiation damages on microstructures
Quantification of (-)-epigallocatechin-3-gallate Inhibition of Migration and Invasion of Oral Squamous Cell Carcinoma Cell Lines Using Real-time Cell Analysis
Catechins found in green tea, in particular (−)-epigallocatechin-3-gallate (EGCG), have antitumor activity. The primary antitumor actions of catechins are anti-oxidative, anti-angiogenic, and anti-metastatic effects. Cell migration and invasion contribute to the metastatic potential of tumors. Real-time cell analysis (RTCA) measures cell migration and invasion in vitro. In the present study, using RTCA, we investigated whether the cell migration and invasion of oral squamous cell carcinomas (OSCCs) of the tongue and floor of the mouth were inhibited by EGCG. Studies were performed using the human SCC-4 and SAS cell lines, which are poorly differentiated OSCCs of the tongue, and the HO-1-u-1 cell line, an OSCC of the floor of the mouth. SCC-4 cells exhibited high cell migration and invasion compared with the SAS and HO-1-u-1 cells. EGCG was most effective in inhibiting the migration and invasion of SCC-4 cells, and inhibited OSCC cell invasion more strongly than it inhibited cell migration. EGCG inhibited the expression of matrix metalloproteinase (MMP)-2, MMP-9, and integrin α1 and β1 mRNA in the OSCC cell lines, particularly SCC-4 cells. The findings of the present study suggest that EGCG inhibits OSCC cell migration and invasion by inhibiting MMP-2, MMP-9, and integrin α1and β1 expression. Thus, EGCG may be a suitable agent or lead compound for the inhibition of OSCC metastasis
Low-Dose Intravenous Alteplase in Wake-Up Stroke
Background and Purpose—We assessed whether lower-dose alteplase at 0.6 mg/kg is efficacious and safe for acute fluid-attenuated inversion recovery-negative stroke with unknown time of onset.
Methods—This was an investigator-initiated, multicenter, randomized, open-label, blinded-end point trial. Patients met the standard indication criteria for intravenous thrombolysis other than a time last-known-well >4.5 hours (eg, wake-up stroke). Patients were randomly assigned (1:1) to receive alteplase at 0.6 mg/kg or standard medical treatment if magnetic resonance imaging showed acute ischemic lesion on diffusion-weighted imaging and no marked corresponding hyperintensity on fluid-attenuated inversion recovery. The primary outcome was a favorable outcome (90-day modified Rankin Scale score of 0–1).
Results—Following the early stop and positive results of the WAKE-UP trial (Efficacy and Safety of MRI-Based Thrombolysis in Wake-Up Stroke), this trial was prematurely terminated with 131 of the anticipated 300 patients (55 women; mean age, 74.4±12.2 years). Favorable outcome was comparable between the alteplase group (32/68, 47.1%) and the control group (28/58, 48.3%; relative risk [RR], 0.97 [95% CI, 0.68–1.41]; P=0.892). Symptomatic intracranial hemorrhage within 22 to 36 hours occurred in 1/71 and 0/60 (RR, infinity [95% CI, 0.06 to infinity]; P>0.999), respectively. Death at 90 days occurred in 2/71 and 2/60 (RR, 0.85 [95% CI, 0.06–12.58]; P>0.999), respectively.
Conclusions—No difference in favorable outcome was seen between alteplase and control groups among patients with ischemic stroke with unknown time of onset. The safety of alteplase at 0.6 mg/kg was comparable to that of standard treatment. Early study termination precludes any definitive conclusions
The effect of febuxostat to prevent a further reduction in renal function of patients with hyperuricemia who have never had gout and are complicated by chronic kidney disease stage 3: study protocol for a multicenter randomized controlled study
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